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Extract from the Register of European Patents

EP About this file: EP2094726

EP2094726 - COMPOSITIONS AND METHODS RELATED TO TOLL-LIKE RECEPTOR-3 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.04.2017
Database last updated on 12.11.2024
Most recent event   Tooltip21.09.2018Lapse of the patent in a contracting state
New state(s): MT
published on 24.10.2018  [2018/43]
Applicant(s)For all designated states
THE TEXAS A&M UNIVERSITY SYSTEM
3369 Tamu
College Station, TX 77843-3369 / US
[2016/23]
Former [2009/36]For all designated states
THE TEXAS A & M UNIVERSITY SYSTEM
3369 Tamu
College Station, TX 77843-3369 / US
Inventor(s)01 / KAO, Cheng C.
1817 Honde Drive
College Station, TX 77840 / US
02 / THARACHAPARAMBA, Ranjith Kumar
2128 Tamu, Room 103
College Station, TX 77843 / US
 [2009/36]
Representative(s)Glawe, Delfs, Moll
Partnerschaft mbB von
Patent- und Rechtsanwälten
Postfach 13 03 91
20103 Hamburg / DE
[N/P]
Former [2016/23]Glawe, Delfs, Moll
Partnerschaft mbB von
Patent- und Rechtsanwälten
Rothenbaumchaussee 58
20148 Hamburg / DE
Former [2009/36]Glawe, Delfs, Moll
Patent- und Rechtsanwälte Rothenbaumchaussee 58
20148 Hamburg / DE
Application number, filing date07870874.015.11.2007
[2009/36]
WO2007US23825
Priority number, dateUS20060859085P15.11.2006         Original published format: US 859085 P
[2009/36]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2008063493
Date:29.05.2008
Language:EN
[2008/22]
Type: A2 Application without search report 
No.:EP2094726
Date:02.09.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 29.05.2008 takes the place of the publication of the European patent application.
[2009/36]
Type: B1 Patent specification 
No.:EP2094726
Date:08.06.2016
Language:EN
[2016/23]
Search report(s)International search report - published on:US16.10.2008
(Supplementary) European search report - dispatched on:EP16.02.2012
ClassificationIPC:C07K14/705, C07K16/00, C07K16/28, C07H21/04, C12P21/02, A61K38/00, A61K39/00, A61P29/00
[2012/13]
CPC:
A61K38/177 (EP); A61P1/16 (EP); A61P11/00 (EP);
A61P11/06 (EP); A61P13/12 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P29/00 (EP); A61P35/00 (EP);
A61P37/06 (EP); A61P43/00 (EP); A61P9/00 (EP);
A61K38/00 (EP) (-)
C-Set:
A61K38/177, A61K2300/00 (EP)
Former IPC [2012/12]C07K14/705, C07K16/00, C07K16/28, C07H21/04, C12P21/02, C12N5/07, A61K38/00, A61K39/00
Former IPC [2009/36]C07K14/705, C07K16/00, C07K16/28, C07H21/04, C12P21/02, C12N5/06, A61K38/00, A61K39/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/23]
Former [2009/36]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL15.06.2009
BA15.06.2009
HR15.06.2009
MK15.06.2009
RS15.06.2009
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN IN ZUSAMMENHANG MIT DEM TOLL-LIKE-REZEPTOR 3[2009/36]
English:COMPOSITIONS AND METHODS RELATED TO TOLL-LIKE RECEPTOR-3[2009/36]
French:COMPOSITIONS ET PROCÉDÉS ASSOCIÉS AU RÉCEPTEUR-3 DE TYPE TOLL[2009/51]
Former [2009/36]COMPOSITIONS ET PROCEDES ASSOCIES AU RECEPTEUR-3 DE TYPE TOLL
Entry into regional phase15.06.2009National basic fee paid 
15.06.2009Search fee paid 
15.06.2009Designation fee(s) paid 
15.06.2009Examination fee paid 
Examination procedure15.06.2009Examination requested  [2009/36]
17.09.2012Amendment by applicant (claims and/or description)
24.02.2015Despatch of a communication from the examining division (Time limit: M04)
23.06.2015Reply to a communication from the examining division
04.01.2016Communication of intention to grant the patent
02.05.2016Fee for grant paid
02.05.2016Fee for publishing/printing paid
02.05.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  24.02.2015
Opposition(s)09.03.2017No opposition filed within time limit [2017/20]
Fees paidRenewal fee
24.11.2009Renewal fee patent year 03
23.11.2010Renewal fee patent year 04
29.11.2011Renewal fee patent year 05
27.11.2012Renewal fee patent year 06
28.11.2013Renewal fee patent year 07
22.12.2014Renewal fee patent year 08
25.11.2015Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
30.11.201408   M06   Fee paid on   22.12.2014
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.11.2007
AT08.06.2016
BE08.06.2016
BG08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
TR08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE15.11.2016
MT15.11.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
[2018/43]
Former [2018/38]HU15.11.2007
AT08.06.2016
BE08.06.2016
BG08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
TR08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE15.11.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
Former [2018/29]HU15.11.2007
AT08.06.2016
BE08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
TR08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE15.11.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
Former [2018/28]HU15.11.2007
AT08.06.2016
BE08.06.2016
CY08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
MC08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE15.11.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
Former [2017/51]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
IE15.11.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
Former [2017/43]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
CH30.11.2016
LI30.11.2016
LU30.11.2016
Former [2017/37]AT08.06.2016
BE08.06.2016
CZ08.06.2016
DK08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SI08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
CH30.11.2016
LI30.11.2016
Former [2017/11]AT08.06.2016
BE08.06.2016
CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
PT10.10.2016
Former [2017/10]BE08.06.2016
CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
PL08.06.2016
RO08.06.2016
SE08.06.2016
SK08.06.2016
GR09.09.2016
IS08.10.2016
Former [2017/09]CZ08.06.2016
EE08.06.2016
ES08.06.2016
FI08.06.2016
IT08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
RO08.06.2016
SE08.06.2016
GR09.09.2016
Former [2016/52]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
NL08.06.2016
SE08.06.2016
GR09.09.2016
Former [2016/51]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
GR09.09.2016
Former [2016/50]ES08.06.2016
FI08.06.2016
LT08.06.2016
LV08.06.2016
Former [2016/49]FI08.06.2016
LT08.06.2016
Former [2016/46]LT08.06.2016
Documents cited:Search[X]WO03022296  (UNIV BOSTON [US], et al) [X] 1,4-7 * [0016],[0044],[0057],[0062]-[0063];; claims 7,10,12 *;
 [A]  - DE BOUTEILLER ODETTE ET AL, "Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 280, no. 46, doi:10.1074/JBC.M507163200, ISSN 0021-9258, (20050906), pages 38133 - 38145, (20050906), XP002522758 [A] 1-10 * page 38136, column 2, paragraph 2 - page 38137, column 1, paragraph 2; figure 2 *

DOI:   http://dx.doi.org/10.1074/JBC.M507163200
 [A]  - ALEXOPOULOU L ET AL, "Recognition of double-stranded RNA and activation of NF-kB by toll-like receptor 3", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20011018), vol. 413, doi:10.1038/35099560, ISSN 0028-0836, pages 732 - 738, XP002968529 [A] 1-10 * page 734, column 2, line 5 - page 735, column 1, line 3; figure 1c *

DOI:   http://dx.doi.org/10.1038/35099560
 [AP]  - C. T. RANJITH-KUMAR ET AL, "Effects of Single Nucleotide Polymorphisms on Toll-like Receptor 3 Activity and Expression in Cultured Cells", JOURNAL OF BIOLOGICAL CHEMISTRY, (20070601), vol. 282, no. 24, doi:10.1074/jbc.M700209200, ISSN 0021-9258, pages 17696 - 17705, XP055018029 [AP] 1-10 * page 17703, column 2, paragraph 3 - page 17704, column 2, paragraph 3; figures 3,6,7 *

DOI:   http://dx.doi.org/10.1074/jbc.M700209200
 [AP]  - RANJITH-KUMAR C T ET AL, "Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain", JOURNAL OF BIOLOGICAL CHEMISTRY 20070302 AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY INC. US,, (20070302), vol. 282, no. 10, pages 7668 - 7678, XP007914953 [AP] 1-10 * the whole document *
 [AP]  - ZHANG SHEN-YING ET AL, "TLR3 deficiency in patients with herpes simplex encephalitis", SCIENCE (WASHINGTON D C), (200709), vol. 317, no. 5844, ISSN 0036-8075, pages 1522 - 1527, XP002668826 [AP] 1-10 * page 1527, column 1, line 4 - line 8 *

DOI:   http://dx.doi.org/10.1126/science.1139522
International search[Y]US2003032090  (HARDIMAN GERARD T [US], et al) [Y] 1-3, 7-12, 16-30, 34-44, 48-49 * , abstract, throughout the document, Figures 1-4, Examples and claims *;
 [Y]WO2006111946  (TRINITY COLLEGE DUBLIN [IE], et al) [Y] 1-3, 7-12, 16-30, 34-44, 48-49 * , abstract, throughout the document, and claims. *;
 [Y]US2003022302  (LEWIS ALAN PETER [GB], et al) [Y] 1-3, 7-12, 16-30, 34-44, 48-49 * , abstract, throughout the document, Example and claims *
by applicantWO03022296
 US5225539
 US2004162413
 US5698155
    - "Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signalling requires multimerization and an acidic pH", DE BOUTEILER ODETTE ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, (20050906), vol. 280, pages 38133 - 38145
    - "Recognition of double-stranded RNA and activation of NF-kB by toll-like receptor 3", ALEXOPOULOU L ET AL., NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, (20011018), vol. 413, pages 732 - 738
    - CHOE, J.; KELKER, M. S.; WILSON, 1. A., SCIENCE, (2005), vol. 309, pages 581 - 585
    - BELL, J. K.; BOTOS, 1.; HALL, P. R.; ASKINS, J.; SHILOACH, J.; SEGAL, D. M.; DAVIES, D. R., PROC NATL ACAD SCI USA, (2005), vol. 102, pages 10976 - 10980
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.