EP2046396 - METHODS AND AGENTS FOR PREPARING 18F-RADIOLABELED FLUORINATING AGENTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.05.2014 Database last updated on 31.08.2024 | Most recent event Tooltip | 15.07.2016 | Lapse of the patent in a contracting state New state(s): TR | published on 17.08.2016 [2016/33] | Applicant(s) | For all designated states The Board of Regents of the University of Nebraska 3835 Holdrege Street Lincoln, NE 68503 / US | [2009/16] | Inventor(s) | 01 /
DIMAGNO, Stephen, G. 2300 Van Dorn Street Lincoln, NE 68502 / US | 02 /
SUN, Haoran 2224 U Street, Apt. No.102 Lincoln, NE 68503 / US | [2009/16] | Representative(s) | Hackney, Nigel John, et al Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB | [N/P] |
Former [2013/29] | Hackney, Nigel John, et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS / GB | ||
Former [2009/16] | Hackney, Nigel John, et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS / GB | Application number, filing date | 07872250.1 | 16.07.2007 | [2009/16] | WO2007US73623 | Priority number, date | US20060831460P | 18.07.2006 Original published format: US 831460 P | [2009/16] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2008082695 | Date: | 10.07.2008 | Language: | EN | [2008/28] | Type: | A2 Application without search report | No.: | EP2046396 | Date: | 15.04.2009 | Language: | EN | The application published by WIPO in one of the EPO official languages on 10.07.2008 takes the place of the publication of the European patent application. | [2009/16] | Type: | B1 Patent specification | No.: | EP2046396 | Date: | 17.07.2013 | Language: | EN | [2013/29] | Search report(s) | International search report - published on: | US | 23.10.2008 | (Supplementary) European search report - dispatched on: | EP | 23.07.2009 | Classification | IPC: | A61K51/04, C07B59/00 | [2009/34] | CPC: |
A61K51/04 (EP,US)
|
Former IPC [2009/16] | A61K51/04 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2009/16] | Title | German: | VERFAHREN UND MITTEL ZUR HERSTELLUNG 18F-STRAHLENMARKIERTER FLUORINIERENDER MITTEL | [2009/16] | English: | METHODS AND AGENTS FOR PREPARING 18F-RADIOLABELED FLUORINATING AGENTS | [2009/16] | French: | PROCÉDÉS ET AGENTS PERMETTANT DE PRÉPARER DES AGENTS FLUORANTS RADIOMARQUÉS 18F | [2009/16] | Entry into regional phase | 09.02.2009 | National basic fee paid | 09.02.2009 | Search fee paid | 09.02.2009 | Designation fee(s) paid | 09.02.2009 | Examination fee paid | Examination procedure | 09.02.2009 | Examination requested [2009/16] | 20.11.2009 | Despatch of a communication from the examining division (Time limit: M08) | 14.07.2010 | Reply to a communication from the examining division | 25.01.2011 | Despatch of a communication from the examining division (Time limit: M08) | 27.09.2011 | Reply to a communication from the examining division | 24.01.2013 | Communication of intention to grant the patent | 28.05.2013 | Fee for grant paid | 28.05.2013 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 20.11.2009 | Opposition(s) | 22.04.2014 | No opposition filed within time limit [2014/26] | Fees paid | Renewal fee | 28.07.2009 | Renewal fee patent year 03 | 26.07.2010 | Renewal fee patent year 04 | 25.07.2011 | Renewal fee patent year 05 | 25.07.2012 | Renewal fee patent year 06 | 06.05.2013 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 16.07.2007 | BG | 17.07.2013 | CY | 17.07.2013 | CZ | 17.07.2013 | EE | 17.07.2013 | FI | 17.07.2013 | LT | 17.07.2013 | LV | 17.07.2013 | MC | 17.07.2013 | MT | 17.07.2013 | PL | 17.07.2013 | RO | 17.07.2013 | SI | 17.07.2013 | SK | 17.07.2013 | TR | 17.07.2013 | GR | 18.10.2013 | IS | 17.11.2013 | [2016/33] |
Former [2016/32] | HU | 16.07.2007 | |
BG | 17.07.2013 | ||
CY | 17.07.2013 | ||
CZ | 17.07.2013 | ||
EE | 17.07.2013 | ||
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
MC | 17.07.2013 | ||
MT | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
SK | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2016/28] | BG | 17.07.2013 | |
CY | 17.07.2013 | ||
CZ | 17.07.2013 | ||
EE | 17.07.2013 | ||
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
MC | 17.07.2013 | ||
MT | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
SK | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2016/25] | BG | 17.07.2013 | |
CY | 17.07.2013 | ||
CZ | 17.07.2013 | ||
EE | 17.07.2013 | ||
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
MC | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
SK | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2016/21] | CY | 17.07.2013 | |
CZ | 17.07.2013 | ||
EE | 17.07.2013 | ||
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
MC | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
SK | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2014/23] | CY | 17.07.2013 | |
CZ | 17.07.2013 | ||
EE | 17.07.2013 | ||
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
SK | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2014/22] | CY | 17.07.2013 | |
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
PL | 17.07.2013 | ||
RO | 17.07.2013 | ||
SI | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2014/18] | CY | 17.07.2013 | |
FI | 17.07.2013 | ||
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
PL | 17.07.2013 | ||
SI | 17.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2014/12] | FI | 17.07.2013 | |
LT | 17.07.2013 | ||
LV | 17.07.2013 | ||
PL | 17.07.2013 | ||
SI | 17.07.2013 | ||
CY | 31.07.2013 | ||
GR | 18.10.2013 | ||
IS | 17.11.2013 | ||
Former [2014/11] | FI | 17.07.2013 | |
LT | 17.07.2013 | ||
PL | 17.07.2013 | ||
CY | 31.07.2013 | ||
IS | 17.11.2013 | ||
Former [2014/10] | LT | 17.07.2013 | |
CY | 31.07.2013 | ||
IS | 17.11.2013 | ||
Former [2014/08] | LT | 17.07.2013 | Documents cited: | Search | [X]US2006089514 (DIMAGNO STEPHEN G [US], et al) [X] 14,17-23 * the whole document *; | [X] - KARL O.CHRISTE ET AL., "Syntheses, properties and structures of anhydrous tetramethylammonium fluoride and its 1:1 adduct with trans-3-amino-2-butenenitrile", J. AM. CHEM. SOC., (1990), vol. 112, pages 7619 - 7625, XP002535739 [X] 14,17-23 * Synthesis of N(CH3)4F left hand column page 7621 * DOI: http://dx.doi.org/10.1021/JA00177A025 | [A] - JAE MIN JEONG ET AL, "Synthesis of No-Carrier-Added [18F]Fluoroacetate", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, JOHN WILEY, CHICHESTER, GB, (19970101), vol. 39, no. 5, ISSN 0362-4803, pages 395 - 399, XP002432125 [A] 1-23 * page 397, preparation of [18F]TBAF * DOI: http://dx.doi.org/10.1002/(SICI)1099-1344(199705)39:5<395::AID-JLCR985>3.0.CO;2-4 | [A] - ROBERT F. CUNICO ET AL., "geminal-Dehalosilylation of alpha-halo-beta,beta-dimethylvinyltrimethylsilanes: generation of isopropylidene carbene", J. ORGANOMET. CHEM., (1978), vol. 162, pages 1 - 16, XP002535740 [A] 1-23 * p10,11 synthesis of tetramethylammonium fluoride and elemental analysis * DOI: http://dx.doi.org/10.1016/S0022-328X(00)89075-0 | [A] - RAMESH K. SHARMA ET AL., "Instability of anhydrous tetra-n-alkylammonium fluorides", J. ORG. CHEM., (1983), vol. 48, pages 2112 - 2114, XP002535741 [A] 1-23 * the whole document * DOI: http://dx.doi.org/10.1021/jo00160a041 | International search | [A] - FORD W.T., "Synthesis of Trineopentylamine", JOURNAL OF ORGANIC CHEMISTRY, vol. 38, no. 20, pages 3614 - 3615, XP008102438 DOI: http://dx.doi.org/10.1021/jo00960a038 | Examination | US4978769 | EP0534317 | US6103659 | - PLESCHKE A. ET AL., "Halex reactions of aromatic compounds catalysed by 2-azaallenium, carbophsophazenium, aminophosphonium and diphosphazenium salts: a carbophosphazenium, a comparative study", J. FLUOR. CHEM., (2004), vol. 125, no. 6, pages 1031 - 1038 | - SHEPPARD T., "Metal catalysed halogen exchange reactions of aryl halides", ORG. BIOMOL. CHEM., (2009), vol. 7, pages 1043 - 1052 | - AMII H ET AL., "C-F Bond Activation in Organic Synthesis", CHEM. REV., (2009), vol. 109, pages 2119 - 2183 | - DIMANGO S. ET AL., "Anhydrous Tetrabutylammonium Fluoride", J. AM. CHEM. SOC., (2005), vol. 127, pages 2050 - 2051 | by applicant | - JAE MIN JEONG ET AL., "Synthesis of No-Carrier-Added [18F]Fluoroacetate", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (19970101), vol. 39, no. 5, doi:doi:10.1002/(SICI)1099-1344(199705)39:5<395::AID-JLCR985>3.0.CO;2-4, pages 395 - 300, XP002432125 DOI: http://dx.doi.org/10.1002/(SICI)1099-1344(199705)39:5<395::AID-JLCR985>3.0.CO;2-4 |