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Extract from the Register of European Patents

EP About this file: EP1985714

EP1985714 - Method and kit for detecting a target molecule employing at least two affinity probes and rolling circle replication of padlock probes [Right-click to bookmark this link]
Former [2008/44]Method for detecting a target molecule employing at least two affinity probes and rolling circle replication of padlock probes
[2011/35]
StatusNo opposition filed within time limit
Status updated on  04.01.2013
Database last updated on 03.10.2024
Most recent event   Tooltip11.01.2013Lapse of the patent in a contracting state
New state(s): CH, LI		published on 13.02.2013  [2013/07]
Applicant(s)For all designated states
Olink AB
Dag Hammarskjölds väg 54A
751 83 Uppsala / SE
[2008/44]
Inventor(s)01 / Landegren, Ulf
Norra Parkvägen 29
75 645 Uppsala / SE
 [2011/41]
Former [2008/44]01 / see applicant
...
Representative(s)Dzieglewska, Hanna Eva, et al
Dehns
St Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[N/P]
Former [2008/44]Dzieglewska, Hanna Eva, et al
Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Application number, filing date08005289.725.03.1999
[2008/44]
Priority number, dateEP1998030227825.03.1998         Original published format: EP 98302278
[2008/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1985714
Date:29.10.2008
Language:EN
[2008/44]
Type: B1 Patent specification 
No.:EP1985714
Date:29.02.2012
Language:EN
[2012/09]
Search report(s)(Supplementary) European search report - dispatched on:EP26.09.2008
ClassificationIPC:C12Q1/68, G01N33/532
[2011/35]
CPC:
C12Q1/6816 (EP,US); C12Q1/6844 (EP,US)
C-Set:
C12Q1/6816, C12Q2531/125, C12Q2525/307, C12Q2521/313 (US,EP);
C12Q1/6816, C12Q2531/125, C12Q2525/307, C12Q2525/301 (EP,US);
C12Q1/6844, C12Q2531/125, C12Q2521/301 (US,EP);
C12Q1/6844, C12Q2531/125, C12Q2525/307, C12Q2521/313 (US,EP)
Former IPC [2008/44]C12Q1/68
Designated contracting statesBE,   CH,   DE,   DK,   FR,   GB,   IT,   LI,   NL,   SE [2008/44]
TitleGerman:Zwei Affinitätsproben und Rolling-Circle-Replikation zur Detektion eines Zielmoleküls verwendende Verfahren und Kit[2011/35]
English:Method and kit for detecting a target molecule employing at least two affinity probes and rolling circle replication of padlock probes[2011/35]
French:Un procédé et une trousse pour détecter un cible utilisant la réplication de cercle de roulement et deux sondes d'affinité[2011/35]
Former [2008/44]Ein Verfahren das zwei Affinitätsproben und Rolling-Circle-Replikation zur Detektion eines Zielmoleküls verwendet
Former [2008/44]Method for detecting a target molecule employing at least two affinity probes and rolling circle replication of padlock probes
Former [2008/44]Un procédé pour détecter un cible utilisant la réplication de cercle de roulement et deux sondes d'affinité
Examination procedure24.04.2009Amendment by applicant (claims and/or description)
24.04.2009Examination requested  [2009/24]
21.09.2011Communication of intention to grant the patent
05.01.2012Fee for grant paid
05.01.2012Fee for publishing/printing paid
Parent application(s)   TooltipEP99917891.6  / EP1066414
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19990917891) is  15.09.2004
Opposition(s)30.11.2012No opposition filed within time limit [2013/06]
Fees paidRenewal fee
20.03.2008Renewal fee patent year 03
20.03.2008Renewal fee patent year 04
20.03.2008Renewal fee patent year 05
20.03.2008Renewal fee patent year 06
20.03.2008Renewal fee patent year 07
20.03.2008Renewal fee patent year 08
20.03.2008Renewal fee patent year 09
20.03.2008Renewal fee patent year 10
20.03.2009Renewal fee patent year 11
26.03.2010Renewal fee patent year 12
18.03.2011Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBE29.02.2012
DK29.02.2012
IT29.02.2012
NL29.02.2012
SE29.02.2012
CH31.03.2012
LI31.03.2012
[2013/07]
Former [2012/50]BE29.02.2012
DK29.02.2012
IT29.02.2012
NL29.02.2012
SE29.02.2012
Former [2012/49]BE29.02.2012
DK29.02.2012
NL29.02.2012
SE29.02.2012
Former [2012/48]BE29.02.2012
NL29.02.2012
SE29.02.2012
Former [2012/37]BE29.02.2012
NL29.02.2012
Former [2012/35]NL29.02.2012
Documents cited:Search[A]WO9719193  (UNIV YALE [US]) [A] 1-7 * see whole doc., esp. claims and figures;; example 5 *;
 [A]  - JOERGER R D ET AL, "ANALYTE DETECTION WITH DNA-LABELED ANTIBODIES AND POLYMERASE CHAIN REACTION", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, (19950901), vol. 41, no. 9, ISSN 0009-9147, pages 1371 - 1377, XP001018334 [A] 1-7 * abstract *
 [A]  - TAKESHI SANO ET AL, "IMMUNO-PCR: VERY SENSITIVE ANTIGEN DETECTION BY MEANS OF SPECIFIC ANTIBODY-DNA CONJUGATES", SCIENCE, WASHINGTON, DC, (19921002), vol. 258, no. 5079, ISSN 0036-8075, pages 120 - 122, XP000384402 [A] 1-7 * abstract *
 [DPX]  - BANER J. ET AL.,, "Signal amplification of padlock probes by rolling circle replication", NUCLEIC ACIDS RESEARCH, (19981115), vol. 26, no. 22, pages 5073 - 5078, XP002112357 [DPX] 1-7 * abstract *

DOI:   http://dx.doi.org/10.1093/nar/26.22.5073
 [PA]  - SCHWEITZER B ET AL, "Inaugural article: immunoassays with rolling circle DNA amplification: a versatile platform for ultrasensitive antigen detection", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, (20000829), vol. 97, no. 18, ISSN 0027-8424, pages 10113 - 10119, XP002207138 [PA] 1-7 * abstract *

DOI:   http://dx.doi.org/10.1073/pnas.170237197
Examination   - JARVIUS MALIN ET AL, "In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, vol. 6, no. 9, doi:10.1074/MCP.M700166-MCP200, ISSN 1535-9476, (20070901), pages 1500 - 1509, (20070612), XP002635677

DOI:   http://dx.doi.org/10.1074/MCP.M700166-MCP200
    - SÖDERBERG O ET AL, "Direct observation of individual endogenous protein complexes in situ by proximity ligation", NATURE METHODS, NATURE PUBLISHING GROUP, GB, vol. 3, no. 12, doi:10.1038/NMETH947, ISSN 1548-7091, (20061201), pages 995 - 1000, (20061029), XP002522344

DOI:   http://dx.doi.org/10.1038/NMETH947
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