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Extract from the Register of European Patents

EP About this file: EP2011875

EP2011875 - Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  18.11.2011
Database last updated on 16.07.2024
Most recent event   Tooltip18.11.2011Application deemed to be withdrawnpublished on 21.12.2011  [2011/51]
Applicant(s)For all designated states
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799 / US
[2009/02]
Inventor(s)01 / Silbiger, Scott M.
21550 Burbank Boulevard, No. 320
Woodland Hills California 91367 / US
02 / Koski, Raymond A.
7 Meeting House Lane
Old Lyme Road Connecticut 06371 / US
 [2009/32]
Former [2009/05]01 / Silbiger, Scott M.
21520 Burbank Boulevard, No. 320
Woodland Hills California 91367 / US
02 / Koski, Raymond A.
7 Meeting House Lane
Old Lyme Connecticut 06371 / US
Former [2009/02]01 / Silbiger, Scott M.
21520 Burbank Boulevard No.114
Woodland Hills California 91367 / US
02 / Koski, Raymond A.
7 Meeting House Lane
Old Lyme Connecticut 06371 / US
Representative(s)Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2009/47]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP 20 Red Lion Street London
WC1R 4PJ / GB
Former [2009/02]Schnappauf, Georg, et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München / DE
Application number, filing date08015056.804.10.1994
[2009/02]
Priority number, dateUS1993013423106.10.1993         Original published format: US 134231
[2009/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2011875
Date:07.01.2009
Language:EN
[2009/02]
Search report(s)(Supplementary) European search report - dispatched on:EP03.12.2008
ClassificationIPC:C12N15/15, C07K14/81, C12N1/21, C12N5/10, A61K48/00, A61K38/57, A61K38/43, A61K38/17, A61K38/48, C07K16/38
[2009/02]
CPC:
A61K38/57 (EP,US); C07K14/8146 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2009/02]
Extension statesLT17.06.2009
SI17.06.2009
TitleGerman:Gewebeinhibitor von Metalloprotease-Typ 3-Zusammensetzung und Verfahren[2009/02]
English:Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods[2009/02]
French:Inhibiteur de tissu d'une composition de métalloprotéase de type trois (TIMP-3) et procédés[2009/02]
Examination procedure03.02.2009Amendment by applicant (claims and/or description)
17.06.2009Examination requested  [2009/31]
03.02.2010Despatch of a communication from the examining division (Time limit: M04)
19.05.2010Reply to a communication from the examining division
07.02.2011Communication of intention to grant the patent
17.06.2011Application deemed to be withdrawn, date of legal effect  [2011/51]
01.08.2011Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2011/51]
Parent application(s)   TooltipEP03005363.1  / EP1319669
EP94115578.0  / EP0648838
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19940115578) is  25.06.1998
Fees paidRenewal fee
26.08.2008Renewal fee patent year 03
26.08.2008Renewal fee patent year 04
26.08.2008Renewal fee patent year 05
26.08.2008Renewal fee patent year 06
26.08.2008Renewal fee patent year 07
26.08.2008Renewal fee patent year 08
26.08.2008Renewal fee patent year 09
26.08.2008Renewal fee patent year 10
26.08.2008Renewal fee patent year 11
26.08.2008Renewal fee patent year 12
26.08.2008Renewal fee patent year 13
26.08.2008Renewal fee patent year 14
26.08.2008Renewal fee patent year 15
13.10.2009Renewal fee patent year 16
12.10.2010Renewal fee patent year 17
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - N. KISHNANI ET AL, "Metalloproteinase inhibitors in the extracellular matrix of cultured human cells", FASEB JOURNAL, BETHESDA, MD US, (19930219), vol. 7, no. 3, page A371, XP001148941 [A] * abstract 2148 *
 [DA]  - N. PAVLOFF ET AL, "A new inhibitor of metalloproteinases from chicken: ChIMP-3", JOURNAL OF BIOLOGICAL CHEMISTRY., BALTIMORE US, (19920825), vol. 267, no. 24, pages 17321 - 17326, XP002250340 [DA] * the whole document *
 [A]  - W. STETLER-STEVENSON ET AL, "Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues", JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS), BALTIMORE, MD US, (19900815), vol. 265, no. 23, pages 13933 - 13938, XP002242912
 [PXY]  - S. SILBIGER ET AL, "Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family", GENE., AMSTERDAM NL, (199406), vol. 141, pages 293 - 297, XP001148985 [PX] 1-20 * the whole document * [Y] 1-20

DOI:   http://dx.doi.org/10.1016/0378-1119(94)90588-6
 [PXY]  - J. URIA ET AL, "Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family", CANCER RESEARCH, (19940415), vol. 54, pages 2091 - 2094, XP001148943 [PX] 1-20 * the whole document * [Y] 1-20
 [PXY]  - APTE SUNEEL S ET AL, "Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22.", GENOMICS, (1994), vol. 19, no. 1, ISSN 0888-7543, pages 86 - 90, XP002250342 [PX] 1-20 * the whole document * [Y] 1-20

DOI:   http://dx.doi.org/10.1006/geno.1994.1016
 [DY]  - WILLENBROCK F ET AL, "The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON, PA.; US, (19930101), vol. 32, no. 16, ISSN 0006-2960, pages 4330 - 4337, XP002985945 [DY] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1021/bi00067a023
 [PA]  - K. LECO ET AL, "Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues", JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS), BALTIMORE, MD US, (19940325), vol. 269, no. 12, pages 9352 - 9360, XP002250343 [PA] * the whole document *
Examination   - HERRON G S ET AL, "Secretion of metalloproteinases by stimulated capillary endothelial cells. II. EXPRESSION OF COLLAGENASE AND STROMELYSIN ACTIVITIES IS REGULATED BY ENDOGENOUS INHIBITORS", JOURNAL OF BIOLOGICAL CHEMISTRY.(MICROFILMS), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19860225), vol. 261, no. 6, pages 2814 - 2818, XP002250341
by applicantUS4179337
 WO8304053
 EP0189784
 US4710473
 EP0398753
    - WILLENBROCK ET AL., BIOCHEMISTRY, (1993), vol. 32, pages 4330 - 4337
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.