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Extract from the Register of European Patents

EP About this file: EP2106446

EP2106446 - STABILIZATION OF CYCLIC PEPTIDE STRUCTURES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  19.12.2014
Database last updated on 06.07.2024
Most recent event   Tooltip19.12.2014Application deemed to be withdrawnpublished on 21.01.2015  [2015/04]
Applicant(s)For all designated states
University of Saskatchewan
Industry Liaison Office 501- 121 Research Dirve
Saskatoon, SK S7N 1K2 / CA
[2009/41]
Inventor(s)01 / GEYER, Ronald, C.
University of Saskatchewan
Health Sciences Building
107 Wiggins Road
Saskatoon, Saskatchewan S7N 5E5 / CA
02 / BARRETO, Kris Michael
14-102 104th Street
Saskatoon, Saskatchewan, S7N 1M8 / CA
 [2013/42]
Former [2009/41]01 / GEYER, Ronald, C.
University of Saskatchewan Health Sciences Building 107 Wiggins Road
Saskatoon, Saskatchewan S7N 5E5 / CA
Representative(s)Zacco Denmark A/S
Arne Jacobsens Allé 15
2300 Copenhagen S / DK
[N/P]
Former [2013/03]Zacco Denmark A/S
Hans Bekkevolds Allé 7
2900 Hellerup / DK
Former [2010/02]Nilausen, Kim
Zacco Denmark A/S Hans Bekkevolds Allé 7
2900 Hellerup / DK
Former [2009/41]Nilausen, Kim
Zacco Denmark A/S Hans Bekkevolds Allé 7
DK-2900 Hellerup / DK
Application number, filing date08700513.810.01.2008
[2009/41]
WO2008CA00048
Priority number, dateUS20070884279P10.01.2007         Original published format: US 884279 P
[2013/42]
Former [2009/41]US20070844279P10.01.2007
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008083493
Date:17.07.2008
Language:EN
[2008/29]
Type: A1 Application with search report 
No.:EP2106446
Date:07.10.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 17.07.2008 takes the place of the publication of the European patent application.
[2009/41]
Search report(s)International search report - published on:CA17.07.2008
(Supplementary) European search report - dispatched on:EP17.05.2010
ClassificationIPC:C12N15/62, C07K16/00, C07K16/46, C07K19/00, C07K7/64, C12N15/11, C12N15/13, C12N15/52, C12N9/00, C12P21/00, C12P21/04, C12Q1/00, G01N33/53, G01N33/68
[2009/41]
CPC:
C07K16/00 (EP,US); G01N33/5008 (EP,US); C07K2317/565 (EP,US);
C07K2317/622 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/41]
TitleGerman:STABILISIERUNG CYCLISCHER PEPTIDSTRUKTUREN[2009/41]
English:STABILIZATION OF CYCLIC PEPTIDE STRUCTURES[2009/41]
French:STABILISATION DE STRUCTURES DE PEPTIDES CYCLIQUES[2009/41]
Entry into regional phase05.08.2009National basic fee paid 
05.08.2009Search fee paid 
05.08.2009Designation fee(s) paid 
05.08.2009Examination fee paid 
Examination procedure05.08.2009Examination requested  [2009/41]
10.12.2010Amendment by applicant (claims and/or description)
13.02.2012Despatch of a communication from the examining division (Time limit: M06)
14.08.2012Reply to a communication from the examining division
10.03.2014Despatch of a communication from the examining division (Time limit: M04)
22.07.2014Application deemed to be withdrawn, date of legal effect  [2015/04]
18.08.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/04]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.02.2012
Fees paidRenewal fee
13.01.2010Renewal fee patent year 03
14.01.2011Renewal fee patent year 04
11.01.2012Renewal fee patent year 05
10.01.2013Renewal fee patent year 06
21.01.2014Renewal fee patent year 07
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]WO0036093  (PENN STATE RES FOUND [US], et al) [Y] 12,13 * page 39 - page 40 *;
 [AP]EP1811031  (MILLEGEN [FR]) [AP] 1-16 * the whole document *;
 [I]  - IWAI H ET AL, "Cyclic green fluorescent protein produced in vivo using an artificially split PI-PfuI intein from Pyrococcus furiosus.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 11 MAY 2001 LNKD- PUBMED:11278952, (20010511), vol. 276, no. 19, ISSN 0021-9258, pages 16548 - 16554, XP002579320 [I] 1,2 * the whole document *

DOI:   http://dx.doi.org/10.1074/JBC.M011639200
 [I]  - XU M-Q ET AL, "THE MECHANISM OF PROTEIN SPLICING AND ITS MODULATION BY MUTATION", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, (19961001), vol. 15, no. 19, ISSN 0261-4189, pages 5146 - 5153, XP001063196 [I] 1,2 * page 5148 *
 [Y]  - WORN A ET AL, "Stability engineering of antibody single-chain Fv fragments", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB LNKD- DOI:10.1006/JMBI.2000.4265, (20010202), vol. 305, no. 5, ISSN 0022-2836, pages 989 - 1010, XP004465987 [Y] 3-16 * page 1001, column L *

DOI:   http://dx.doi.org/10.1006/jmbi.2000.4265
 [Y]  - XU M Q ET AL, "Intein-mediated ligation and cyclization of expressed proteins.", METHODS (SAN DIEGO, CALIF.) JUL 2001 LNKD- PUBMED:11403575, (200107), vol. 24, no. 3, ISSN 1046-2023, pages 257 - 277, XP002579321 [Y] 3-16 * page 271, column R *

DOI:   http://dx.doi.org/10.1006/METH.2001.1187
 [A]  - DING Y ET AL, "Crystal Structure of a Mini-intein Reveals a Conserved Catalytic Module Involved in Side Chain Cyclization of Asparagine during Protein Splicing", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US LNKD- DOI:10.1074/JBC.M306197200, (20031003), vol. 278, no. 40, ISSN 0021-9258, pages 39133 - 39142, XP008111031 [A] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M306197200
 [T]  - BARRETO K ET AL, "A Genetic Screen for Isolating Lariat Peptide Inhibitors of Protein Function", CHEMISTRY AND BIOLOGY, CURRENT BIOLOGY, LONDON, GB LNKD- DOI:10.1016/J.CHEMBIOL.2009.10.012, vol. 16, no. 11, ISSN 1074-5521, (20091125), pages 1148 - 1157, (20091126), XP026782604 [T] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.chembiol.2009.10.012
 [A]  - SALEH LANA ET AL, Protein splicing in cis and in trans., CHEMICAL RECORD (NEW YORK, N.Y.) 2006 LNKD- PUBMED:16900466, VOL. 6, NR. 4, PAGE(S) 183 - 193, (2006), ISSN 1527-8999, XP002579322 [A] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1002/tcr.20082
International search[X]WO0036093  (PENN STATE RES FOUND [US], et al);
 [Y]  - XU M.-Q. AND PERLER F.B., "The mechanism of protein splicing and its modulation by mutation", EMBO J., (199610), vol. 15, no. 19, pages 5146 - 5153, XP001063196
 [Y]  - COOPER A.A. ET AL., "Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision", EMBO J., (199306), vol. 12, no. 6, pages 2575 - 2583, XP002105837
 [Y]  - KAWASAKI M. ET AL., "Identification of three core regions essential for protein splicing of the yeast Vma1 protozyme", J. BIOL. CHEM., (199706), vol. 272, no. 25, pages 15668 - 15674, XP008111032

DOI:   http://dx.doi.org/10.1074/jbc.272.25.15668
 [Y]  - PERLER F.B. ET AL., "Compilation and analysis of intein sequences", NUC. ACIDS RES., (199703), vol. 25, no. 6, pages 1087 - 1093, XP002154590

DOI:   http://dx.doi.org/10.1093/nar/25.6.1087
 [A]  - DING Y. ET AL., "Crystal Structure of a Mini-intein Reveals a Conserved Catalytic Module Involved in Side Chain Cyclization of Asparagine during Protein Splicing", J. BIOL. CHEM., (20031003), vol. 278, no. 40, pages 39133 - 39142, XP008111031

DOI:   http://dx.doi.org/10.1074/jbc.M306197200
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.