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Extract from the Register of European Patents

EP About this file: EP2120915

EP2120915 - POLYELECTROLYTE PRECIPITATION AND PURIFICATION OF ANTIBODIES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.08.2012
Database last updated on 25.09.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Genentech, Inc.
1 DNA Way
South San Francisco, CA 94080 / US
[2009/48]
Inventor(s)01 / FAHRNER, Robert, L.
3816 Pasadena Drive
San Mateo, California 94403 / US
02 / FRANKLIN, Jayme
1715 Marina Court, Apt. E
San Mateo, California 94403 / US
03 / MCDONALD, Paul, J.
534 Valley St.
San Francisco, California 94131 / US
04 / PERAM, Thanmaya
174 Lu Anne Drive
Campbell, California 95008 / US
05 / SISODIYA, Vikram
849 DiFiore Drive, No. 1
San José, California 95128 / US
06 / VICTA, Corazon
50 Iron Horse Lane
Walnut Creek, California 94597 / US
 [2009/48]
Representative(s)van der Hoff, Hilary Mary, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2009/48]King, Hilary Mary, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date08705841.810.01.2008
[2009/48]
WO2008US50747
Priority number, dateUS20070886068P22.01.2007         Original published format: US 886068 P
US2007001344613.12.2007         Original published format: US 13446
[2009/48]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2008091740
Date:31.07.2008
Language:EN
[2008/31]
Type: A2 Application without search report 
No.:EP2120915
Date:25.11.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 31.07.2008 takes the place of the publication of the European patent application.
[2009/48]
Type: B1 Patent specification 
No.:EP2120915
Date:28.09.2011
Language:EN
[2011/39]
Search report(s)International search report - published on:EP20.11.2008
ClassificationIPC:A61K31/198, C07K1/30, C07K1/36, C07K16/00, C07K16/28
[2009/48]
CPC:
C07K16/00 (EP,US); C07K1/36 (EP,KR,US); A61K31/198 (KR);
C07K1/32 (EP,US); C07K16/28 (KR); C07K16/2803 (EP,US);
C07K16/2863 (EP,US); C07K16/2878 (EP,US); C07K16/2887 (EP,US);
C07K2317/24 (EP,US); C07K2317/734 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/48]
Extension statesAL10.08.2009
BA10.08.2009
MK10.08.2009
RS10.08.2009
TitleGerman:ABSCHEIDUNG VON POLYELEKTROLYTEN UND REINIGUNG VON ANTIKÖRPERN[2009/48]
English:POLYELECTROLYTE PRECIPITATION AND PURIFICATION OF ANTIBODIES[2009/48]
French:PRÉCIPITATION DE POLYÉLECTROLYTE ET PURIFICATION DE PROTÉINES[2009/48]
Entry into regional phase10.08.2009National basic fee paid 
10.08.2009Designation fee(s) paid 
10.08.2009Examination fee paid 
Examination procedure07.08.2009Amendment by applicant (claims and/or description)
10.08.2009Examination requested  [2009/48]
19.04.2010Despatch of a communication from the examining division (Time limit: M04)
25.08.2010Reply to a communication from the examining division
09.09.2010Despatch of a communication from the examining division (Time limit: M04)
26.10.2010Reply to a communication from the examining division
10.06.2011Communication of intention to grant the patent
12.08.2011Fee for grant paid
12.08.2011Fee for publishing/printing paid
Divisional application(s)EP11173495.0  / EP2377527
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.04.2010
Opposition(s)29.06.2012No opposition filed within time limit [2012/36]
Fees paidRenewal fee
13.01.2010Renewal fee patent year 03
14.01.2011Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU10.01.2008
AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
MT28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
TR28.09.2011
BG28.12.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
LU10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
[2014/34]
Former [2014/27]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
MT28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
TR28.09.2011
BG28.12.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
LU10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2014/21]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
MT28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
TR28.09.2011
BG28.12.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2013/35]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
MT28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
BG28.12.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2013/29]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
BG28.12.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2013/08]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
NO28.12.2011
GR29.12.2011
IE10.01.2012
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2012/37]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
PL28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
NO28.12.2011
GR29.12.2011
IS28.01.2012
PT30.01.2012
MC31.01.2012
Former [2012/35]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
DK28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
NO28.12.2011
GR29.12.2011
IS28.01.2012
PT30.01.2012
Former [2012/23]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
EE28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
RO28.09.2011
SI28.09.2011
SK28.09.2011
NO28.12.2011
GR29.12.2011
IS28.01.2012
PT30.01.2012
Former [2012/21]AT28.09.2011
BE28.09.2011
CY28.09.2011
CZ28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
SI28.09.2011
NO28.12.2011
GR29.12.2011
IS28.01.2012
Former [2012/18]AT28.09.2011
BE28.09.2011
CY28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
SI28.09.2011
NO28.12.2011
GR29.12.2011
Former [2012/13]AT28.09.2011
CY28.09.2011
FI28.09.2011
HR28.09.2011
LT28.09.2011
LV28.09.2011
SI28.09.2011
NO28.12.2011
GR29.12.2011
Cited inInternational search[A]US3737377  (STERNBERG M) [A] 1-23 * the whole document *;
 [A]EP0162034  (MONSANTO CO [US]) [A] 1-23 * page 14, lines 1-26 * * page 17, line 1 - page 19, line 9 * * page 14, line 18 - page 15, line 14 * * claims 1-18 *;
 [A]WO9314110  (MIDDLESEX SCIENCES INC [US]) [A] 1-23 * the whole document *;
 [XA]US5641870  (RINDERKNECHT ERNST H [US], et al) [X] 24 * page 17, column L, lines 39-48 * [A] 1-23,25-38;
 [A]WO0000038  (MICHAEL FOODS INC [US]) [A] 24-38 * the whole document *;
 [A]EP1275437  (KANEGAFUCHI CHEMICAL IND [JP]) [A] 1-23 * the whole document *;
 [A]US2004121339  (ZHOU JIZHONG [US], et al) [A] 1-23 * page 2, column R, paragraph 5 * * page 3, column L, paragraph 3 * * page 6, column L, paragraph 3 - column R, paragraph 1 *;
 [XA]WO2004092393  (GENENTECH INC [US], et al) [X] 24 * page 2, line 34 - page 3, line 26 * [A] 1-23,25-38;
 [A]WO2005051359  (UNIV ILLINOIS [US], et al) [A] 1-23 * page 27, paragraph 1 * * page 30, paragraph 3 - page 31, paragraph 1 * * page 36 * * page 49 - page 50 *;
 [A]  - KERSCHER L ET AL, "Precipitation methods for the determination of LDL-cholesterol.", CLINICAL BIOCHEMISTRY APR 1985, (198504), vol. 18, no. 2, ISSN 0009-9120, pages 118 - 125, XP002475905 [A] 1-23 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0009-9120(85)80093-X
 [A]  - SHALOVA IRINA N ET AL, "Interaction of polyanions with basic proteins, 2(a) : influence of complexing polyanions on the thermo-aggregation of oligomeric enzymes.", MACROMOLECULAR BIOSCIENCE 15 DEC 2005, (20051215), vol. 5, no. 12, ISSN 1616-5187, pages 1184 - 1192, XP002493855 [A] 1-23 * the whole document *

DOI:   http://dx.doi.org/10.1002/mabi.200500142
 [A]  - MUSTAFAEV M., "Functionally Biopolymer Systems", SIGMA, JOURNAL OF ENGINEERING AND NATURAL SCIENCES, ISTANBUL, (2004), vol. 4, pages 1 - 28, XP002493856 [A] 1-23 * page 2 - page 4 * * figures 10,16,17 *
 [A]  - BERDICK M ET AL, "The interaction of catalase with synthetic polyelectrolytes.", THE JOURNAL OF BIOLOGICAL CHEMISTRY FEB 1954, (195402), vol. 206, no. 2, ISSN 0021-9258, pages 959 - 971, XP002493857 [A] 1-23 * the whole document *
 [A]  - BOZZANO A G ET AL, "SEPARATION OF PROTEINS FROM POLYELECTROLYTES BY ULTRAFILTRATION", JOURNAL OF MEMBRANE SCIENCE, ELSEVIER SCIENTIFIC PUBL.COMPANY. AMSTERDAM, NL, (19910101), vol. 55, no. 1 / 02, ISSN 0376-7388, pages 181 - 198, XP000175418 [A] 1-23 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0376-7388(00)82334-0
 [A]  - FISHER R R ET AL, "Polyelectrolyte precipitation of proteins: I. The effect of reactor conditions.", BIOTECHNOLOGY AND BIOENGINEERING 5 SEP 1988, (19880905), vol. 32, no. 6, ISSN 0006-3592, pages 777 - 785, XP002493858 [A] 1-23 * the whole document *

DOI:   http://dx.doi.org/10.1002/bit.260320609
 [XA]  - RISKE ET AL, "The use of chitosan as a flocculant in mammalian cell culture dramatically improves clarification throughput without adversely impacting monoclonal antibody recovery", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 128, no. 4, ISSN 0168-1656, (20070113), pages 813 - 823, (20080828), XP005916242 [X] 24,25,28,31,34-38 * page 814, column R, paragraph 3 - page 815, column R, paragraph 1 * * page 816, column R, paragraph 2 - page 817, column L, paragraph 1 * * page 820, column R, paragraph 1; table 2 * * page 822, column L, paragraph 2 - column R, paragraph 2 * [A] 26,27,29,30,32,33

DOI:   http://dx.doi.org/10.1016/j.jbiotec.2006.12.023
 [A]  - MOERBE J L ET AL, "Release of miniantibodies from E. coli cells into the supernatant at low and high cell densities", MICROBIOLOGICAL RESEARCH, (199712), vol. 152, no. 4, ISSN 0944-5013, pages 385 - 394, XP008095547 [A] 24-38 * the whole document *
 [A]  - AUNINS J G ET AL, "INDUCED FLOCCULATION OF ANIMAL CELLS IN SUSPENSION CULTURE", BIOTECHNOLOGY AND BIOENGINEERING, (1989), vol. 34, no. 5, ISSN 0006-3592, pages 629 - 638, XP002493859 [A] 24-38 * the whole document *

DOI:   http://dx.doi.org/10.1002/bit.260340507
 [A]  - ALDINGTON ET AL, "Scale-up of monoclonal antibody purification processes", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES & APPLICATIONS, ELSEVIER, AMSTERDAM, NL, (20070116), vol. 848, no. 1, ISSN 1570-0232, pages 64 - 78, XP005922828 [A] 24-38 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jchromb.2006.11.032
 [A]  - SCOPES ET AL, "Protein Purification - Principles and Practice", PROTEIN PURIFICATION. PRINCIPLES AND PRACTICE, NEW YORK, SPRINGER VERLAG, US, (19870101), pages 21 - 71, XP002109597 [A] 1-38 * the whole document *
 [A]  - "PLASMA MEMBRANE: RAPID ISOLATION AND EXPOSURE OF The CYTOPLASMIC SURFACE BY USE OF POSITIVELY CHARGED BEADS", SCIENCE, WASHINGTON, DC, (19770121), vol. 195, no. 4275, ISSN 0036-8075, pages 302 - 304, XP009016723 [A] 24-38 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.831278
by applicantUS5641870
 WO2004092393
    - WANG ET AL., BIOTECHNOL. PROG., (1996), vol. 12, pages 356 - 362
    - VEIS, A., AM. CHEM. SOC. DIV. POLYM. CHEM. PREPR., (1991), vol. 32, no. 1, page 596
    - DAINIAK ET AL., ANALYTICAL BIOCHEM., (2000), vol. 277, pages 58 - 66
    - DUBIN ET AL., SEP. PURIF. METHODS, (1994), vol. 23, pages 1 - 16
    - COOPER ET AL., CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, (2005), vol. 10, pages 52 - 78
    - MATTISON ET AL., MACROMOL. SYMP., (1999), vol. 140, pages 53 - 76
    - CARLSSON ET AL., J. AM. CHEM. SOC., (2003), vol. 125, pages 3140 - 3149
    - RISKE ET AL., J BIOTECH., (2007), vol. 128, pages 813 - 823
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.