Extract from the Register of European Patents

EP About this file: EP2139848

EP2139848 - DEUTERIUM LABELLED KETAMINE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.03.2011
Database last updated on 09.04.2026
Most recent event   Tooltip25.03.2011Application deemed to be withdrawnpublished on 27.04.2011  [2011/17]
Applicant(s)For all designated states
Auspex Pharmaceuticals, Inc.
1261 Liberty Way, Suite C
Vista, CA 92081-8356 / US
[2010/01]
Inventor(s)01 / GANT, Thomas, G.
1261 Liberty Way, Suite C
Vista, CA 92081-8356 / US
02 / SARSHAR, Sepehr
1261 Liberty Way, Suite C
Vista, CA 92081-8356 / US
 [2010/01]
Representative(s)Smaggasgale, Gillian Helen
WP Thompson
138 Fetter Lane
London EC4A 1BT / GB
[N/P]
Former [2010/01]Smaggasgale, Gillian Helen
W.P. Thompson & Co, 55 Drury Lane
London WC2B 5SQ / GB
Application number, filing date08746923.525.04.2008
[2010/01]
WO2008US61598
Priority number, dateUS20070914121P26.04.2007         Original published format: US 914121 P
[2010/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008134525
Date:06.11.2008
Language:EN
[2008/45]
Type: A1 Application with search report 
No.:EP2139848
Date:06.01.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 06.11.2008 takes the place of the publication of the European patent application.
[2010/01]
Search report(s)International search report - published on:EP06.11.2008
ClassificationIPC:C07C225/20, A61K31/135, A61K51/00, A61P23/00, A61P25/00
[2010/01]
CPC:
A61K45/06 (EP,US); A61P17/02 (EP); A61P23/00 (EP);
A61P25/00 (EP); A61P25/04 (EP); A61P25/28 (EP);
A61P29/00 (EP); A61P31/04 (EP); A61P39/00 (EP);
A61P43/00 (EP); A61P9/10 (EP); C07C225/20 (EP,US);
C07B2200/05 (EP,US); C07C2601/14 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/01]
TitleGerman:DEUTERIUM-MARKIERTE KETAMINE[2010/01]
English:DEUTERIUM LABELLED KETAMINE[2010/01]
French:KETAMINE MARQUEE PAR DEUTERIUM[2010/01]
Entry into regional phase26.10.2009National basic fee paid 
26.10.2009Designation fee(s) paid 
26.10.2009Examination fee paid 
Examination procedure26.10.2009Examination requested  [2010/01]
05.01.2010Amendment by applicant (claims and/or description)
03.11.2010Application deemed to be withdrawn, date of legal effect  [2011/17]
09.12.2010Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2011/17]
Fees paidPenalty fee
Additional fee for renewal fee
30.04.201003   M06   Not yet paid
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Cited inInternational search[X]   LOUIS Y LEUNGT AND THOMAS A BAILLIE: "Studies on the biotransformation of ketamine. II-Quanitative Significance of the N-Demethylation pathway in rats in vivo determined by a novel stable isotope technique", BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, WILEY, LONDON, vol. 18, 1 January 1989 (1989-01-01), pages 401 - 404, XP009103139, ISSN: 0887-6134 [X] 1-27 * the whole document *

DOI:   http://dx.doi.org/10.1002/bms.1200180607
 [X]   MIN-KUN HUANG ET AL.: "Quantitative detection of ketamine, norketamine, and dehydronorketamine in urine using chemical derivatization followed by gas chromatography-mass spectrometry", JOURNAL OF CHROMATOGRAPHY B, vol. 820, 26 April 2005 (2005-04-26), pages 165 - 173, XP002488176 [X] 1-27 * abstract * * page 1666: Experimental 2.1. Chemicals and reagents *

DOI:   http://dx.doi.org/10.1016/j.jchromb.2005.03.004
 [X]   DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TREVOR, ANTHONY J. ET AL: "Stereoselective metabolism of ketamine enantiomers", XP002488177, retrieved from STN Database accession no. 103:89 [X] 1-27 * abstract *
 [X]   PHENCYCLIDINE RELAT. ARYLCYCLOHEXYLAMINES: PRESENT FUTURE APPL., PROC. JT. FR.-US SEMIN. CHEM., PHARMACOL., PRESENT FUTURE THER. APPL. DRUG ABUSE ASPECTS ARYLCYCLOHEXYLAMINES , MEETING DATE 1982, 279-89. EDITOR(S): KAMENKA, JEAN MARC; DOMINO, EDWAR, 1983
 [Y]   HARTVIG PER ET AL: "Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers", CLINICAL PHARMACOLOGY & THERAPEUTICS, MOSBY-YEAR BOOK, ST LOUIS, MO, US, vol. 58, no. 2, 1 August 1995 (1995-08-01), pages 165 - 173, XP009103120, ISSN: 0009-9236 [Y] 28-89 * abstract *

DOI:   http://dx.doi.org/10.1016/0009-9236(95)90194-9
 [Y]   SHIUE C ET AL: "Carbon-11 Labelled Ketamine--Synthesis, Distribution in Mice and PET Studies in Baboons", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 24, no. 2, 1 February 1997 (1997-02-01), pages 145 - 150, XP004058585, ISSN: 0969-8051 [Y] 28-89 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0969-8051(96)00186-2
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