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Extract from the Register of European Patents

EP About this file: EP2150618

EP2150618 - IL-12 IMMUNOTHERAPY FOR CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.08.2018
Database last updated on 13.07.2024
FormerThe patent has been granted
Status updated on  08.09.2017
FormerGrant of patent is intended
Status updated on  04.09.2017
FormerExamination is in progress
Status updated on  09.08.2017
FormerGrant of patent is intended
Status updated on  20.03.2017
Most recent event   Tooltip26.06.2020Lapse of the patent in a contracting state
New state(s): CY
published on 29.07.2020  [2020/31]
Applicant(s)For all designated states
University Health Network
R. Fraser Elliott Building, Room 1S-417 190 Elizabeth Street
Toronto, ON M5G 2C4 / CA
[2010/06]
Inventor(s)01 / MEDIN, Jeffrey, A.
251 Cocksfield Avenue
North York, Ontario M3H 3T6 / CA
02 / PAIGE, Christopher, J.
39 McKenzie Ave.
Toronto, Ontario M4W 1K1 / CA
 [2010/06]
Representative(s)Daniels, Jeffrey Nicholas, et al
Page White & Farrer Limited
Bedford House
21A John Street
London WC1N 2BF / GB
[N/P]
Former [2017/41]Daniels, Jeffrey Nicholas, et al
Page White & Farrer
Bedford House
John Street
London WC1N 2BF / GB
Former [2010/06]Hill, Christopher Michael, et al
Page White & Farrer Bedford House John Street
London, WC1N 2BF / GB
Application number, filing date08748251.905.05.2008
[2010/06]
WO2008CA00849
Priority number, dateUS20070916136P04.05.2007         Original published format: US 916136 P
[2010/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008134879
Date:13.11.2008
Language:EN
[2008/46]
Type: A1 Application with search report 
No.:EP2150618
Date:10.02.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 13.11.2008 takes the place of the publication of the European patent application.
[2010/06]
Type: B1 Patent specification 
No.:EP2150618
Date:11.10.2017
Language:EN
[2017/41]
Search report(s)International search report - published on:CA13.11.2008
(Supplementary) European search report - dispatched on:EP06.05.2011
ClassificationIPC:C12N15/867, A61K38/20, A61K39/00, A61K48/00, A61P35/00, A61P35/02, A61P37/04, C07K14/54, C12N15/24, C12N5/10, C12P21/02
[2010/06]
CPC:
A61K38/208 (EP,US); A61K35/545 (US); A61K39/00114 (US);
A61K39/4611 (EP); A61K39/4613 (EP); A61K39/46444 (EP);
A61K48/005 (EP,US); A61P35/00 (EP); A61P35/02 (EP);
A61P37/04 (EP); C07K14/5434 (US); C12N15/86 (EP,US);
C12N7/00 (US); A61K2039/515 (US); A61K2039/53 (US);
A61K2039/585 (US); A61K2239/31 (EP); A61K2239/38 (EP);
A61K2239/48 (EP); C07K2319/00 (US); C12N2710/16122 (US);
C12N2730/10122 (US); C12N2740/13043 (EP,US); C12N2740/15043 (US);
C12N2740/15071 (US); C12N2740/16022 (US); C12N2800/40 (US);
C12N2830/48 (US); C12N2830/60 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/41]
Former [2010/06]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:IL-12-IMMUNTHERAPIE GEGEN KREBS[2010/06]
English:IL-12 IMMUNOTHERAPY FOR CANCER[2010/06]
French:IMMUNOTHÉRAPIE DU CANCER AVEC L'IL-2[2010/06]
Entry into regional phase04.12.2009National basic fee paid 
04.12.2009Search fee paid 
04.12.2009Designation fee(s) paid 
04.12.2009Examination fee paid 
Examination procedure04.12.2009Examination requested  [2010/06]
21.10.2010Observations by third parties
01.12.2011Amendment by applicant (claims and/or description)
16.03.2012Despatch of a communication from the examining division (Time limit: M04)
26.07.2012Reply to a communication from the examining division
12.05.2014Despatch of a communication from the examining division (Time limit: M06)
24.11.2014Reply to a communication from the examining division
29.05.2015Despatch of a communication from the examining division (Time limit: M06)
08.12.2015Reply to a communication from the examining division
05.01.2016Despatch of a communication from the examining division (Time limit: M04)
05.05.2016Reply to a communication from the examining division
21.03.2017Communication of intention to grant the patent
31.07.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
31.07.2017Fee for grant paid
31.07.2017Fee for publishing/printing paid
04.09.2017Information about intention to grant a patent
04.09.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17184090.3  / EP3293266
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.03.2012
Opposition(s)12.07.2018No opposition filed within time limit [2018/38]
Fees paidRenewal fee
30.04.2010Renewal fee patent year 03
27.05.2011Renewal fee patent year 04
29.05.2012Renewal fee patent year 05
31.05.2013Renewal fee patent year 06
30.05.2014Renewal fee patent year 07
29.05.2015Renewal fee patent year 08
31.05.2016Renewal fee patent year 09
30.05.2017Renewal fee patent year 10
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU05.05.2008
AT11.10.2017
CY11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
PT11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
TR11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
MT05.05.2018
BE31.05.2018
CH31.05.2018
LI31.05.2018
[2020/31]
Former [2020/27]HU05.05.2008
AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
PT11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
TR11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
MT05.05.2018
BE31.05.2018
CH31.05.2018
LI31.05.2018
Former [2020/16]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
TR11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
MT05.05.2018
BE31.05.2018
CH31.05.2018
LI31.05.2018
Former [2020/08]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
MT05.05.2018
BE31.05.2018
CH31.05.2018
LI31.05.2018
Former [2019/24]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
BE31.05.2018
CH31.05.2018
LI31.05.2018
Former [2019/19]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
IE05.05.2018
LU05.05.2018
CH31.05.2018
LI31.05.2018
Former [2019/17]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
LU05.05.2018
CH31.05.2018
LI31.05.2018
Former [2019/12]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
CH31.05.2018
LI31.05.2018
Former [2019/06]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
MC11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/52]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SI11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/42]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
NL11.10.2017
PL11.10.2017
RO11.10.2017
SE11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/37]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
NL11.10.2017
PL11.10.2017
SE11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/35]AT11.10.2017
CZ11.10.2017
DK11.10.2017
EE11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
NL11.10.2017
SE11.10.2017
SK11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/24]AT11.10.2017
FI11.10.2017
HR11.10.2017
LT11.10.2017
LV11.10.2017
NL11.10.2017
SE11.10.2017
BG11.01.2018
NO11.01.2018
GR12.01.2018
IS11.02.2018
Former [2018/21]FI11.10.2017
LT11.10.2017
NL11.10.2017
NO11.01.2018
Former [2018/17]NL11.10.2017
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DOI:   http://dx.doi.org/10.1038/sj.cgt.7700201
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DOI:   http://dx.doi.org/10.1089/hum.1997.8.18-2217
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DOI:   http://dx.doi.org/10.1038/MT.SJ.6300122
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DOI:   http://dx.doi.org/10.1038/sj.gt.3302947
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DOI:   http://dx.doi.org/10.1038/SJ.MT.6300060
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DOI:   http://dx.doi.org/10.2174/1381612033454261
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DOI:   http://dx.doi.org/10.1111/J.1582-4934.2008.00412.X
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DOI:   http://dx.doi.org/10.1186/1742-4690-1-37
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DOI:   http://dx.doi.org/10.1096/FJ.02-0900FJE
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DOI:   http://dx.doi.org/10.1016/S1368-8375(00)00093-2
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    - SZYMCZAK AL; VIGNALI DA, "Development of 2A peptide-based strategies in the design of multicistronic vectors", EXPERT OPIN BIOL THER., (2005), vol. 5, no. 5, doi:doi:10.1517/14712598.5.5.627, pages 627 - 638, XP055378453

DOI:   http://dx.doi.org/10.1517/14712598.5.5.627
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DOI:   http://dx.doi.org/10.1089/hum.1997.8.18-2217
    - PIZZAFERRATO,E., "B7-2 Expression Above A Threshold Elicits Anti-Tumor Immunity As Effective As Interleukin-12 And Prolongs Survival In Murine B-Cell Lymphoma", INT.J.CANCER, PITTSBURGH, PA, USA, (2004), vol. 110, pages 61 - 69, XP003028068

DOI:   http://dx.doi.org/10.1002/ijc.20085
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.