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Extract from the Register of European Patents

EP About this file: EP2154147

EP2154147 - A TRUNCATED L1 PROTEIN OF HUMAN PAPILLOMAVIRUS 16 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.08.2016
Database last updated on 07.10.2024
Most recent event   Tooltip17.08.2018Lapse of the patent in a contracting state
New state(s): BG		published on 19.09.2018  [2018/38]
Applicant(s)For all designated states
Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
No. 31 Kexueyuan Road Changping District Beijing
102206 / CN
For all designated states
Xiamen University
No. 422 Si Ming Nan Road Siming District
Xiamen, Fujian 361005 / CN
[2010/07]
Inventor(s)01 / GU, Ying
No. 422 Simingnan Road
Siming District
Xiamen, Fujian 361005 / CN
02 / LI, Shaowei
No. 422 Simingnan Road
Siming District
Xiamen, Fujian 361005 / CN
03 / WEI, Minxi
No. 422 Simingnan Road
Siming District
Xiamen, Fujian 361005 / CN
04 / XIAN, Yangling
No. 422 Simingnan Road
Siming District
Xiamen, Fujian 361005 / CN
05 / LUO, Wenxin
No.422 Si Ming Nan Road
Siming District
Xiamen, Fujian 361005 / CN
06 / XIA, Ningshao
No.422 Si Ming Nan Road
Siming District
Xiamen, Fujian 361005 / CN
 [2015/41]
Former [2010/07]01 / GU, Ying
No. 422 Simingnan Road Siming District
Xiamen, Fujian 361005 / CN
02 / LI, Shaowei
No. 422 Simingnan Road Siming District
Xiamen, Fujian 361005 / CN
03 / WEI, Minxi
No. 422 Simingnan Road Siming District
Xiamen, Fujian 361005 / CN
04 / XIAN, Yangling
No. 422 Simingnan Road Siming District
Xiamen, Fujian 361005 / CN
05 / LUO, Wenxin
No.422 Si Ming Nan Road Siming District
Xiamen, Fujian 361005 / CN
06 / XIA, Ningshao
No.422 Si Ming Nan Road Siming District
Xiamen, Fujian 361005 / CN
Representative(s)van Heuvel, Margaretha, et al
De Vries & Metman
Overschiestraat 180
1062 XK Amsterdam / NL
[2015/41]
Former [2010/07]van Heuvel, Margaretha, et al
De Vries & Metman Overschiestraat 180
1062 XK Amsterdam / NL
Application number, filing date08748431.729.04.2008
[2010/07]
WO2008CN00872
Priority number, dateCN200719776229.04.2007         Original published format: CN200710097762
CN200810876123.01.2008         Original published format: CN200810008761
[2010/07]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008134934
Date:13.11.2008
Language:ZH
[2008/46]
Type: A1 Application with search report 
No.:EP2154147
Date:17.02.2010
Language:EN
[2010/07]
Type: B1 Patent specification 
No.:EP2154147
Date:07.10.2015
Language:EN
[2015/41]
Search report(s)International search report - published on:CN13.11.2008
(Supplementary) European search report - dispatched on:EP04.10.2011
ClassificationIPC:C12N7/02, C07K14/025, A61K39/12
[2015/13]
CPC:
C07K14/005 (EP,US); A61K39/12 (EP,US); A61P15/02 (EP);
A61P31/20 (EP); A61P35/00 (EP); A61P37/04 (EP);
C12N7/00 (EP,US); A61K2039/5258 (EP,US); A61K2039/55505 (EP,US);
A61K2039/55566 (EP,US); A61K2039/70 (EP,US); C12N2710/20022 (EP,US);
C12N2710/20034 (EP,US) (-)
Former IPC [2010/07]C07K14/025, C12N15/37, C12N7/02, C07K1/18, A61K39/12, A61P31/20, A61P15/02, A61P35/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/41]
Former [2010/07]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL24.11.2009
BA24.11.2009
MK24.11.2009
RS24.11.2009
TitleGerman:GEKÜRZTES L1-PROTEIN DES HUMANEN PAPILLOMAVIRUS 16[2010/07]
English:A TRUNCATED L1 PROTEIN OF HUMAN PAPILLOMAVIRUS 16[2010/07]
French:PROTÉINE L1 TRONQUÉE DU PAPILLOMAVIRUS 16 HUMAIN[2010/07]
Entry into regional phase24.11.2009Translation filed 
24.11.2009National basic fee paid 
24.11.2009Search fee paid 
24.11.2009Designation fee(s) paid 
24.11.2009Examination fee paid 
Examination procedure24.11.2009Examination requested  [2010/07]
01.05.2012Amendment by applicant (claims and/or description)
14.02.2013Despatch of a communication from the examining division (Time limit: M06)
14.08.2013Reply to a communication from the examining division
26.11.2013Cancellation of oral proceeding that was planned for 17.12.2013
05.12.2013Despatch of a communication from the examining division (Time limit: M02)
17.12.2013Date of oral proceedings (cancelled)
12.02.2014Reply to a communication from the examining division
16.12.2014Despatch of a communication from the examining division (Time limit: M02)
17.12.2014Reply to a communication from the examining division
29.04.2015Communication of intention to grant the patent
24.08.2015Fee for grant paid
24.08.2015Fee for publishing/printing paid
24.08.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.02.2013
Opposition(s)08.07.2016No opposition filed within time limit [2016/37]
Fees paidRenewal fee
31.03.2010Renewal fee patent year 03
27.04.2011Renewal fee patent year 04
28.03.2012Renewal fee patent year 05
29.04.2013Renewal fee patent year 06
25.03.2014Renewal fee patent year 07
10.04.2015Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU29.04.2008
AT07.10.2015
BE07.10.2015
BG07.10.2015
CY07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
MC07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
TR07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
IE29.04.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
MT30.04.2016
[2018/38]
Former [2018/32]HU29.04.2008
AT07.10.2015
BE07.10.2015
CY07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
MC07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
TR07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
IE29.04.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
MT30.04.2016
Former [2018/29]HU29.04.2008
AT07.10.2015
BE07.10.2015
CY07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
MC07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
TR07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
IE29.04.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
Former [2018/28]HU29.04.2008
AT07.10.2015
BE07.10.2015
CY07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
MC07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
IE29.04.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
Former [2017/38]AT07.10.2015
BE07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
IE29.04.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
Former [2017/07]AT07.10.2015
BE07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
LU29.04.2016
CH30.04.2016
LI30.04.2016
Former [2017/04]AT07.10.2015
BE07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
LU29.04.2016
Former [2017/03]AT07.10.2015
BE07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
Former [2016/49]AT07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SI07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
BE30.04.2016
Former [2016/36]AT07.10.2015
CZ07.10.2015
EE07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
RO07.10.2015
SE07.10.2015
SK07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
BE30.04.2016
Former [2016/34]AT07.10.2015
CZ07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
SE07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
Former [2016/25]AT07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
LV07.10.2015
PL07.10.2015
SE07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
Former [2016/24]AT07.10.2015
ES07.10.2015
FI07.10.2015
HR07.10.2015
LT07.10.2015
PL07.10.2015
SE07.10.2015
NO07.01.2016
GR08.01.2016
IS07.02.2016
PT08.02.2016
Former [2016/23]ES07.10.2015
HR07.10.2015
LT07.10.2015
SE07.10.2015
NO07.01.2016
IS07.02.2016
Former [2016/22]ES07.10.2015
LT07.10.2015
NO07.01.2016
IS07.02.2016
Former [2016/21]ES07.10.2015
LT07.10.2015
NO07.01.2016
Former [2016/20]ES07.10.2015
LT07.10.2015
Documents cited:Search[XI]  - CHEN X S ET AL, "Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, (20010316), vol. 307, no. 1, doi:10.1006/JMBI.2000.4464, ISSN 0022-2836, pages 173 - 182, XP004469210 [X] 1-7,9 * page 173 - page 181; figure 4; table 1 * [I] 10-13

DOI:   http://dx.doi.org/10.1006/jmbi.2000.4464
International search[X]WO0054730  (HARVARD COLLEGE [US], et al);
 [Y]WO03078455  (GLAXOSMITHKLINE BIOLOG SA [BE], et al);
 [XP]US6649167  (HALLEK MICHAEL [DE], et al);
 [X]CN1478790  (MA RUNLIN [CN]);
 [X]CN1821410  (ZENG YI [CN]);
 [X]CN101153280  (XIAMEN UNIVERSITY BEIJING WANT [CN]);
 [X]  - CHEN X.S. ET AL., "Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16", MOLECULAR CELL, (200003), vol. 5, no. 3, pages 557 - 567, XP002216859

DOI:   http://dx.doi.org/10.1016/S1097-2765(00)80449-9
 [A]  - SUN X. ET AL., "Purification of human papillomavirus type 16 major capsid protein L1", JOURNAL OF CHENDE MEDICAL COLLEGE, (20020601), vol. 19, no. 2, pages 85 - 87
ExaminationWO9420137
 US2002193565
 WO2004056389
    - DE VILLIERS E-M ET AL, "Classification of papillomaviruses", VIROLOGY, ELSEVIER, AMSTERDAM, NL, (20040620), vol. 324, no. 1, doi:10.1016/J.VIROL.2004.03.033, ISSN 0042-6822, pages 17 - 27, XP004512668

DOI:   http://dx.doi.org/10.1016/j.virol.2004.03.033
    - JANA S ET AL, "Strategies for efficient production of heterologous proteins in Escherichia coli", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, (20050501), vol. 67, no. 3, doi:10.1007/S00253-004-1814-0, ISSN 1432-0614, pages 289 - 298, XP019331816

DOI:   http://dx.doi.org/10.1007/s00253-004-1814-0
    - LUO W X ET AL, "[Construction and application of an Escherichia coli high effective expression vector with an enhancer].", SHENG WU GONG CHENG XUE BAO = CHINESE JOURNAL OF BIOTECHNOLOGY SEP 2000, (200009), vol. 16, no. 5, ISSN 1000-3061, pages 578 - 581, XP008166031
    - NING-XIA FANG ET AL, "Post translational modifications of recombinant human Papillomavirus type 6b major capsid protein", VIRUS RESEARCH, (19990401), vol. 60, no. 2, doi:10.1016/S0168-1702(98)00117-8, ISSN 0168-1702, pages 113 - 121, XP055090344

DOI:   http://dx.doi.org/10.1016/S0168-1702(98)00117-8
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    - BANKS, L.; G MATLASHEWSKI ET AL., J GEN VIROL, (1987), vol. 68, no. 12, pages 3081 - 9
    - KELSALL, S. R.; J. K. KULSKI, J VIROL METHODS, (1995), vol. 53, no. 1, pages 75 - 90
    - LI, M.; T. P. CRIPE ET AL., J VIROL, (1997), vol. 71, no. 4, pages 2988 - 95
    - LUO XINWEN ET AL., CHINESE JOURNAL OF BIOTECHNOLOGY, (2000), vol. 16, pages 53 - 57
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    - The Molecular Cloning Experiment Guide
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.