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Extract from the Register of European Patents

EP About this file: EP2157979

EP2157979 - CALCIUM CHANNEL PROTEINS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.05.2019
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  08.06.2018
FormerGrant of patent is intended
Status updated on  22.05.2018
FormerExamination is in progress
Status updated on  10.04.2018
FormerGrant of patent is intended
Status updated on  26.11.2017
FormerExamination is in progress
Status updated on  02.10.2017
FormerGrant of patent is intended
Status updated on  21.05.2017
FormerExamination is in progress
Status updated on  10.05.2017
Most recent event   Tooltip23.07.2021Lapse of the patent in a contracting state
New state(s): MT		published on 25.08.2021  [2021/34]
Applicant(s)For all designated states
Calcimedica, Inc.
505 Coast Blvd S., Ste 209
La Jolla, CA 92037 / US
[2010/09]
Inventor(s)01 / STAUDERMAN, Kenneth, A.
3615 Lotus Drive
San Diego, CA 92106 / US
02 / ROOS, Jack
10527 Stony Ridge Ct.
San Diego, CA 92131 / US
03 / VELICELEBI, Gonul
4688 Tarantella Lane
San Diego, CA 92130 / US
 [2010/09]
Representative(s)Avidity IP
Broers Building
Hauser Forum
21 JJ Thomson Avenue
Cambridge CB3 0FA / GB
[2018/28]
Former [2010/09]Cole, William Gwyn, et al
HLBBshaw Merlin House Falconry Court Baker's Lane
Epping, Essex CM16 5DQ / GB
Application number, filing date08756325.027.05.2008
[2010/09]
WO2008US64915
Priority number, dateUS20070939922P24.05.2007         Original published format: US 939922 P
[2010/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008148108
Date:04.12.2008
Language:EN
[2008/49]
Type: A1 Application with search report 
No.:EP2157979
Date:03.03.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 04.12.2008 takes the place of the publication of the European patent application.
[2010/09]
Type: B1 Patent specification 
No.:EP2157979
Date:11.07.2018
Language:EN
[2018/28]
Search report(s)International search report - published on:KR04.12.2008
(Supplementary) European search report - dispatched on:EP25.05.2010
ClassificationIPC:A61K38/17, C07H21/04, C07K14/435
[2010/09]
CPC:
G01N33/5008 (EP,US); G01N33/5076 (EP,US); G01N33/6872 (EP,US);
G01N2333/705 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2018/28]
Former [2010/09]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:KALZIUMKANALPROTEINE UND IHRE VERWENDUNGEN[2010/09]
English:CALCIUM CHANNEL PROTEINS AND USES THEREOF[2010/09]
French:PROTÉINES DE CANAL DE CALCIUM ET LEUR UTILISATION[2010/09]
Entry into regional phase17.12.2009National basic fee paid 
17.12.2009Search fee paid 
17.12.2009Designation fee(s) paid 
17.12.2009Examination fee paid 
Examination procedure17.12.2009Examination requested  [2010/09]
05.04.2011Amendment by applicant (claims and/or description)
04.04.2012Despatch of a communication from the examining division (Time limit: M06)
15.10.2012Reply to a communication from the examining division
07.10.2013Despatch of a communication from the examining division (Time limit: M04)
15.05.2014Reply to a communication from the examining division
27.06.2014Despatch of a communication from the examining division (Time limit: M06)
04.02.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
13.04.2015Reply to a communication from the examining division
24.07.2015Despatch of a communication from the examining division (Time limit: M04)
26.11.2015Reply to a communication from the examining division
09.05.2016Despatch of a communication from the examining division (Time limit: M04)
02.08.2016Reply to a communication from the examining division
22.05.2017Communication of intention to grant the patent
27.09.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
27.09.2017Fee for grant paid
27.09.2017Fee for publishing/printing paid
27.11.2017Communication of intention to grant the patent
06.04.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
22.05.2018Information about intention to grant a patent
22.05.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.04.2012
Opposition(s)12.04.2019No opposition filed within time limit [2019/25]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
13.04.2015Request for further processing filed
13.04.2015Full payment received (date of receipt of payment)
Request granted
15.05.2015Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
15.05.2014Request for further processing filed
15.05.2014Full payment received (date of receipt of payment)
Request granted
30.05.2014Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
05.04.2011Request for further processing filed
05.04.2011Full payment received (date of receipt of payment)
Request granted
18.04.2011Decision despatched
Fees paidRenewal fee
25.06.2010Renewal fee patent year 03
25.05.2011Renewal fee patent year 04
25.05.2012Renewal fee patent year 05
10.05.2013Renewal fee patent year 06
12.06.2014Renewal fee patent year 07
12.05.2015Renewal fee patent year 08
27.05.2016Renewal fee patent year 09
30.05.2017Renewal fee patent year 10
29.05.2018Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
31.05.201003   M06   Fee paid on   25.06.2010
31.05.201407   M06   Fee paid on   12.06.2014
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.05.2008
AT11.07.2018
CY11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
MT11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
TR11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
PT11.11.2018
[2021/34]
Former [2021/32]HU27.05.2008
AT11.07.2018
CY11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
TR11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
PT11.11.2018
Former [2021/26]AT11.07.2018
CY11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
TR11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
PT11.11.2018
Former [2020/29]AT11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
TR11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
PT11.11.2018
Former [2020/16]AT11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
TR11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2020/07]AT11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
MC11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/37]AT11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
PL11.07.2018
RO11.07.2018
SI11.07.2018
SK11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/24]AT11.07.2018
CZ11.07.2018
EE11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
PL11.07.2018
RO11.07.2018
SK11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/22]AT11.07.2018
CZ11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
PL11.07.2018
RO11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/21]AT11.07.2018
ES11.07.2018
HR11.07.2018
IT11.07.2018
LT11.07.2018
LV11.07.2018
PL11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/12]AT11.07.2018
ES11.07.2018
HR11.07.2018
LT11.07.2018
LV11.07.2018
PL11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/11]AT11.07.2018
HR11.07.2018
LT11.07.2018
PL11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/10]AT11.07.2018
LT11.07.2018
PL11.07.2018
BG11.10.2018
NO11.10.2018
GR12.10.2018
IS11.11.2018
Former [2019/08]LT11.07.2018
NO11.10.2018
IS11.11.2018
Former [2019/07]LT11.07.2018
Documents cited:Search[XP]WO2007139926  (UNIV CALIFORNIA [US], et al) [XP] 1-10,13-15 * page 21 - page 22 *;
 [A]  - YEROMIN A V ET AL, "Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai", NATURE, NATURE PUBLISHING GROUP, LONDON, GB LNKD- DOI:10.1038/NATURE05108, vol. 443, no. 7108, ISSN 0028-0836, (20060914), pages 226 - 229, (20060820), XP002489915 [A] 1-10,13-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/nature05108
 [X]  - STRANGE ET AL, "Physiological roles of STIM1 and Orai1 homologs and CRAC channels in the genetic model organism Caenorhabditis elegans", CELL CALCIUM (EDINBURGH), CHURCHILL LIVINGSTONE MEDICAL JOURNALS, EDINBURGH, GB LNKD- DOI:10.1016/J.CECA.2007.02.007, (20070321), vol. 42, no. 2, ISSN 0143-4160, pages 193 - 203, XP022136170 [X] 6-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ceca.2007.02.007
 [A]  - PUTNEY ET AL, "Recent breakthroughs in the molecular mechanism of capacitative calcium entry (with thoughts on how we got here)", CELL CALCIUM (EDINBURGH), CHURCHILL LIVINGSTONE MEDICAL JOURNALS, EDINBURGH, GB, (20070308), vol. 42, no. 2, ISSN 0143-4160, pages 103 - 110, XP022136161 [A] 1-10,13-16 * the whole document *
International search[X]  - LORIN-NEBEL C. ET AL., "CRAC channel activity in C. elegans is mediated by orai1 and STIM1 homologues and is essential for ovulation and fertility", J. PHYSIOL., (2007), vol. 580, pages 67 - 85, XP008125064

DOI:   http://dx.doi.org/10.1113/jphysiol.2006.124883
 [X]  - SOBOLOFF J. ET AL., "Calcium signals mediated by STIM and Orai proteins-a new paradigm in inter-organelle communication", BIOCHIMICA, ET BIOPHYSICA ACTA, (2006), vol. 1763, pages 1161 - 1168, XP005776843

DOI:   http://dx.doi.org/10.1016/j.bbamcr.2006.09.023
 [X]  - SMYTH J.T. ET AL., "Emerging perspectives in store-prepared Ca2+entry: Roles of Orai, Stim and TRP", BIOCHIMICA ET BIOPHYSICA ACTA, (2006), vol. 1763, pages 1147 - 1160, XP005776842

DOI:   http://dx.doi.org/10.1016/j.bbamcr.2006.08.050
 [Y]  - KUHNS D.B. ET AL., "Ca2+-dependent production and release of IL-8 in human neutrophils", J. IMMUNOL., (1998), vol. 161, pages 4332 - 4339, XP008124922
Examination   - PEINELT CHRISTINE ET AL, "Amplification of CRAC current by STIM1 and CRACM1 (Orai1)", NATURE CELL BIOLOGY, MACMILLAN MAGAZINES LTD, vol. 8, no. 7, doi:10.1038/NCB1435, ISSN 1465-7392, (20060701), pages 771 - 773,1, (20060530), XP002489913

DOI:   http://dx.doi.org/10.1038/ncb1435
    - R Tsien ET AL, "Mechanisms of calcium channel modulation by [beta]-adrenergic agents and dihydropyridine calcium agonists", Journal of Molecular and Cellular Cardiology, (19860701), vol. 18, no. 7, doi:10.1016/S0022-2828(86)80941-5, ISSN 0022-2828, pages 691 - 710, XP055080963

DOI:   http://dx.doi.org/10.1016/S0022-2828(86)80941-5
by applicantWO2007081804
 US2007031814
 US2007105160
 US2002034728
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.