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Extract from the Register of European Patents

EP About this file: EP2185698

EP2185698 - KINASE INHIBITORS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.02.2016
Database last updated on 13.07.2024
Most recent event   Tooltip13.10.2017Lapse of the patent in a contracting state
New state(s): BG, CY, HU, SE, TR		published on 15.11.2017  [2017/46]
Applicant(s)For all designated states
Purdue Research Foundation
1281 Win Hentschel Boulevard
West Lafayette, IN 47906 / US
[2014/19]
Former [2010/20]For all designated states
Purdue Research Foundation
3000 Kent Avenue
West Lafayette, IN 47906-1075 / US
Inventor(s)01 / PANITCH, Alyssa
807 Hillcrest Road
West Lafayette, IN 47906 / US
02 / SEAL, Brandon
3722 Litchfield Place
West Lafayette, IN 47906 / US
03 / WARD, Brian
8845 N. County Rd 925 E.
Brownsburg, IN 46112-9266 / US
 [2014/32]
Former [2010/20]01 / PANITCH, Alyssa
807 Hillcrest Road
West Lafayette, IN 47906 / US
02 / SEAL, Brandon
3722 Litchfield Place
West Lafayette, IN 47906 / US
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2015/17]
Former [2010/47]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Former [2010/20]Beresford, Keith Denis Lewis, et al
Beresford & Co. 16 High Holborn London
WC1V 6BX / GB
Application number, filing date08797416.807.08.2008
[2010/20]
WO2008US72525
Priority number, dateUS20070963941P07.08.2007         Original published format: US 963941 P
US20070994970P24.09.2007         Original published format: US 994970 P
[2010/20]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009021137
Date:12.02.2009
Language:EN
[2009/07]
Type: A2 Application without search report 
No.:EP2185698
Date:19.05.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 12.02.2009 takes the place of the publication of the European patent application.
[2010/20]
Type: B1 Patent specification 
No.:EP2185698
Date:22.04.2015
Language:EN
[2015/17]
Search report(s)International search report - published on:US09.07.2009
(Supplementary) European search report - dispatched on:EP27.02.2012
ClassificationIPC:C12N9/12, A61K38/00, C07K7/06, C07K7/08, C07K14/47
[2012/13]
CPC:
A61K38/005 (EP,US); C07K14/4747 (US); A61K38/16 (US);
A61P35/00 (EP); A61P35/02 (EP); A61P43/00 (EP);
C07K14/4703 (EP,US); C07K7/06 (EP,US); C07K7/08 (EP,US) (-)
Former IPC [2010/20]C12N9/12
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/17]
Former [2010/20]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesALNot yet paid
BANot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:KINASEHEMMER UND IHRE VERWENDUNG[2010/20]
English:KINASE INHIBITORS AND USES THEREOF[2010/20]
French:INHIBITEURS DE KINASE ET LEURS UTILISATIONS[2010/20]
Entry into regional phase01.03.2010National basic fee paid 
01.03.2010Search fee paid 
01.03.2010Designation fee(s) paid 
01.03.2010Examination fee paid 
Examination procedure01.03.2010Examination requested  [2010/20]
25.09.2012Amendment by applicant (claims and/or description)
11.02.2013Despatch of a communication from the examining division (Time limit: M04)
14.06.2013Reply to a communication from the examining division
26.09.2013Despatch of a communication from the examining division (Time limit: M04)
06.02.2014Reply to a communication from the examining division
20.05.2014Communication of intention to grant the patent
26.09.2014Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
03.11.2014Communication of intention to grant the patent
11.03.2015Fee for grant paid
11.03.2015Fee for publishing/printing paid
11.03.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.02.2013
Opposition(s)25.01.2016No opposition filed within time limit [2016/13]
Fees paidRenewal fee
17.08.2010Renewal fee patent year 03
25.08.2011Renewal fee patent year 04
27.08.2012Renewal fee patent year 05
27.08.2013Renewal fee patent year 06
27.08.2014Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU07.08.2008
BG22.04.2015
CY22.04.2015
EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
MC22.04.2015
MT22.04.2015
PL22.04.2015
RO22.04.2015
SE22.04.2015
SI22.04.2015
SK22.04.2015
TR22.04.2015
NO22.07.2015
GR23.07.2015
LU07.08.2015
IS22.08.2015
PT24.08.2015
[2017/39]
Former [2017/21]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
MC22.04.2015
MT22.04.2015
PL22.04.2015
RO22.04.2015
SI22.04.2015
SK22.04.2015
NO22.07.2015
GR23.07.2015
LU07.08.2015
IS22.08.2015
PT24.08.2015
Former [2016/24]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
MC22.04.2015
PL22.04.2015
RO22.04.2015
SI22.04.2015
SK22.04.2015
NO22.07.2015
GR23.07.2015
LU07.08.2015
IS22.08.2015
PT24.08.2015
Former [2016/18]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
MC22.04.2015
PL22.04.2015
RO22.04.2015
SK22.04.2015
NO22.07.2015
GR23.07.2015
LU07.08.2015
IS22.08.2015
PT24.08.2015
Former [2016/17]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
PL22.04.2015
RO22.04.2015
SK22.04.2015
NO22.07.2015
GR23.07.2015
LU07.08.2015
IS22.08.2015
PT24.08.2015
Former [2016/10]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
PL22.04.2015
RO22.04.2015
SK22.04.2015
NO22.07.2015
GR23.07.2015
IS22.08.2015
PT24.08.2015
Former [2016/09]EE22.04.2015
FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
NO22.07.2015
GR23.07.2015
IS22.08.2015
PT24.08.2015
Former [2015/50]FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
NO22.07.2015
GR23.07.2015
IS22.08.2015
PT24.08.2015
Former [2015/49]FI22.04.2015
HR22.04.2015
LT22.04.2015
LV22.04.2015
NO22.07.2015
GR23.07.2015
PT24.08.2015
Documents cited:Search[XA]WO2006053315  (MASSACHUSETTS INST TECHNOLOGY [US], et al) [X] 1,7-14 * claims 1-9,16-18 * [A] 2-6;
 [A]WO2007053512  (UNIV ARIZONA STATE [US], et al) [A] 1-14 * claim -; sequence 4 *;
 [XDA]  - HAYESS K ET AL, "Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, vol. 53, no. 9, doi:10.1016/S0006-2952(96)00877-5, ISSN 0006-2952, (19970509), pages 1239 - 1247, (19971217), XP008119459 [XD] 1,7-14 * abstract * [A] 2-6

DOI:   http://dx.doi.org/10.1016/S0006-2952(96)00877-5
International search[X]US2007078092  (LIVNAH NURIT [IL], et al);
 [X]  - KWON ET AL., "The cdk2 Binding Domain of p27Kip Correlates with the Inhibition of the Kinase Activity of cdk2/Cyclin Complexes", BIOCHEM BIOPHYS RES COMM, (1996), vol. 220, pages 703 - 709, XP005176770

DOI:   http://dx.doi.org/10.1006/bbrc.1996.0468
 [Y]  - KOONIN ET AL., "Origin and evolution of eukaryotic apoptosis: the bacterial connection", CELL DEATH DIFFER., (200204), vol. 9, no. 4, pages 394 - 404, XP008130373
 [Y]  - DE MARZO ET AL., "Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells", AM J PATHOL, (199809), vol. 153, no. 3, pages 911 - 919, XP002199162
 [Y]  - WORM ET AL., "Aberrant p27Kip1 promoter methylation in malignant melanoma'", ONCOGENE, (20001019), vol. 19, no. 44, pages 5111 - 5115, XP008130371
 [Y]  - WANG ET AL., "p27Kip1 overexpression causes apoptotic death of mammalian cells", ONCOGENE, (19971211), vol. 15, no. 24, pages 2991 - 2997, XP008130378
 [Y]  - AMANO ET AL., "µFormation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho- Kinase", SCIENCE, (19970228), vol. 275, no. 5304, pages 1308 - 1311, XP002947561

DOI:   http://dx.doi.org/10.1126/science.275.5304.1308
 [Y]  - HAAPASALO ET AL., "Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival'.", BIOCHEM BIOPHY RES COMMUN, (20010209), vol. 280, no. 5, pages 1352 - 1358, XP008130380

DOI:   http://dx.doi.org/10.1006/bbrc.2001.4296
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.