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Extract from the Register of European Patents

EP About this file: EP2203748

EP2203748 - MEANS AND METHODS FOR THE DETECTION OF CONTRAST MEDIUM-INDUCED NEPHROTOXICITY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  09.11.2012
Database last updated on 09.04.2026
Most recent event   Tooltip09.11.2012Application deemed to be withdrawnpublished on 12.12.2012  [2012/50]
Applicant(s)For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MT  NL  NO  PL  PT  RO  SE  SI  SK  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2012/08]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MT  NL  NO  PL  PT  RO  SE  SI  SK  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Former [2010/27]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MT  NL  NO 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / HESS, Georg
Oppenheimer Strasse 82
55130 Mainz / DE
02 / HORSCH, Andrea
Christian-Morgenstern-Strasse 11
68259 Mannheim / DE
03 / ZDUNEK, Dietmar
Eli Ney Strasse 3
82327 Tutzing / DE
 [2010/27]
Representative(s)Dick, Alexander, et al
Herzog Fiesser & Partner Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
[N/P]
Former [2010/27]Dick, Alexander, et al
Herzog Fiesser & Partner Patentanwälte Bad Kreuznacher Strasse 27-29
68309 Mannheim / DE
Application number, filing date08804750.125.09.2008
[2010/27]
WO2008EP62861
Priority number, dateEP2007011748728.09.2007         Original published format: EP 07117487
[2010/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009040400
Date:02.04.2009
Language:EN
[2009/14]
Type: A1 Application with search report 
No.:EP2203748
Date:07.07.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 02.04.2009 takes the place of the publication of the European patent application.
[2010/27]
Search report(s)International search report - published on:EP02.04.2009
ClassificationIPC:G01N33/68
[2010/27]
CPC:
G01N33/6893 (EP,US); G01N33/5302 (EP,US); G01N2800/347 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/27]
TitleGerman:MITTEL UND VERFAHREN ZUR ERKENNUNG KONTRASTMEDIENINDUZIERTER NEPHROTOXIZITÄT[2010/27]
English:MEANS AND METHODS FOR THE DETECTION OF CONTRAST MEDIUM-INDUCED NEPHROTOXICITY[2010/27]
French:MOYEN ET PROCÉDÉS DE DÉTECTION DE NÉPHROTOXICITÉ INDUITE PAR UN PRODUIT DE CONTRASTE[2011/51]
Former [2010/27]MOYEN ET PROCÉDÉS DE DÉTECTION DE NÉPHROTOXICITÉ INDUITE PAR UN MILIEU DE CONTRASTE
Entry into regional phase19.03.2010National basic fee paid 
19.03.2010Designation fee(s) paid 
19.03.2010Examination fee paid 
Examination procedure28.07.2009Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.03.2010Examination requested  [2010/27]
17.06.2010Amendment by applicant (claims and/or description)
11.08.2010Despatch of a communication from the examining division (Time limit: M06)
21.02.2011Reply to a communication from the examining division
30.01.2012Communication of intention to grant the patent
12.06.2012Application deemed to be withdrawn, date of legal effect  [2012/50]
17.07.2012Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2012/50]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.08.2010
Fees paidRenewal fee
07.09.2010Renewal fee patent year 03
08.09.2011Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
30.09.201205   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[Y] US2005158801  (HU HUAIZHONG et al.)
 [A] WO2007041623  (BIOSITE INC et al.)
 [X]   NAKAMURA TSUKASA ET AL: "Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy", AMERICAN JOURNAL OF KIDNEY DISEASES, W.B. SAUNDERS, PHILADELPPHIA, PA, US, vol. 47, no. 3, March 2006 (2006-03-01), pages 439 - 444, XP008085321, ISSN: 0272-6386 [X] 16,17 * the whole document *

DOI:   http://dx.doi.org/10.1053/j.ajkd.2005.11.006
 [A]   DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 2005, OHTA SATOSHI ET AL: "[Effects of intravascular contrast media on urinary excretion of liver fatty acid-binding protein]", XP002457132, Database accession no. NLM15971886 [A] 1-15 * the whole document *
 [A]   NIPPON JINZO GAKKAI SHI 2005, vol. 47, no. 4, 2005, pages 437 - 444, ISSN: 0385-2385 * pages 13,15,20 *
 [A]   SCHIAVINA G ET AL: "[Nephrotoxicity of contrast media. Comparison of iopamidol and diatrizoate by measurement of urinary enzymes after urography]", LA RADIOLOGIA MEDICA APR 1984, vol. 70, no. 4, April 1984 (1984-04-01), pages 176 - 179, XP002465050, ISSN: 0033-8362 [A] 1-17 * the whole document *
 [DY]   ANONYMOUS: "Acute tubular necrosis", MERCK MANUAL - ONLINE MEDICAL LIBRARY, May 2007 (2007-05-01), XP002465051, Retrieved from the Internet [retrieved on 20080117] [DY] 1-8,10-13,15 * abstract * * page 440, paragraph METHODS * * page 441, paragraph DISCUSSION * * page 443, lines 12-15 * * tables 2,4 *
 [A]   WIECEK ANDRZEJ ET AL: "Adiponectin--an adipokine with unique metabolic properties.", NEPHROLOGY, DIALYSIS, TRANSPLANTATION : OFFICIAL PUBLICATION OF THE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION - EUROPEAN RENAL ASSOCIATION APR 2007, vol. 22, no. 4, April 2007 (2007-04-01), pages 981 - 988, XP002465132, ISSN: 0931-0509 [A] * relevant for assessing the lack of unity * * abstract *

DOI:   http://dx.doi.org/10.1093/ndt/gfl814
by applicantWO2008084003
 US5744305
   KATZBERG, KIDNEY INT SUPPL, vol. 100, 2006, pages 3 - 7 [X] 16,17 * pages 13,15,20 *
   ASPELIN, P., NEPHROTOXICITY AND THE ROLE OF CONTRAST MEDIA, RADIATION MEDICINE, vol. 22, no. 6, 2004, pages 377 - 378 [Y] 1-9,11-15 * abstract * * page 2188, paragraph "hUII concentrations in human urine" * * page 2189, column RIGHT, paragraph 2 * * figure 3 *
   SOLOMON, R. J. ET AL.: "Cardiac Angiography in Renally Impaired Patients", CIRCULATION, vol. 112, 2007, pages 3189 - 3196 [A] 1-17 * the whole document *
   LEVEY, ANNALS OF INTERNAL MEDICINE, 1999, pages 461 - 470 [DY] 1-8,10-13,15 * abstract * * page 440, paragraph METHODS * * page 441, paragraph DISCUSSION * * page 443, lines 12-15 * * tables 2,4 *
   H AKGUN ET AL.: "Are gadolinium-based contrast media nephrotoxic? A renal biopsy study", ARCH PATHOL LAB MED, vol. 130, 2006, pages 1354 [A] * relevant for assessing the lack of unity * * abstract *
   LABARRERE, JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 18, no. 2, 2003, pages 77 - 88
   KADOWAKI ET AL.: "Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome", J CLIN INVEST., vol. 116, no. 7, 2006, pages 1784 - 1792 [Y] 1-8,10-15
   SMITH; WATERMAN, ADD. APL. MATH., vol. 2, 1981, pages 482 [Y] 14 * abstract *
   NEEDLEMAN; WUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 [A] * the whole document *
   PEARSON; LIPMAN, PROC. NATL. ACAD SCI., vol. 85, 1988, pages 2444 [A] * the whole document *
   NOLAN, TRENDS BIOTECHNOL., vol. 20, no. 1, 2002, pages 9 - 12
   KAMIJO ET AL.: "Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease", MOL. CELL BIOCHEM., vol. 284, 2006
   NAKAMURA ET AL.: "Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy", AM J KIDNEY DIS., vol. 47, no. 3, 2006, pages 439 - 44
   NAKAMURA ET AL., LOC. CIT
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.