Extract from the Register of European Patents

EP About this file: EP2379066

EP2379066 - USE OF OPIOID ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT IN THE TREATMENT OF RETINAL DEGENERATIVE DISEASES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.01.2015
Database last updated on 09.04.2026
Most recent event   Tooltip14.06.2019Change - lapse in a contracting statepublished on 17.07.2019  [2019/29]
Applicant(s)For all designated states
Imuneks Farma Ilaç Sanayi Ve Ticaret A.S.
Pak is Merkezi Prof. Dr. Bülent Tarcan
Sok. No: 5/1
Gayrettepe
34349 Istanbul / TR
[2014/13]
Former [2014/03]For all designated states
Imunek Farma Ilaç Sanayi Ve Ticaret A.S.
Pak is Merkezi Prof. Dr. Bülent Tarcan
Sok. No: 5/1
Gayrettepe
34349 Istanbul / TR
Former [2011/43]For all designated states
Ak Kimya Ithalat-ihracat Ve Sanayii Anonim Sirketi
Prof. Dr. Bülent Tarcan Sokak No.5 34349 Gayrettepe
Istanbul / TR
Inventor(s)01 / PISAK, Ibrahim Mustafa Iskender
Park Is Merkezi Prof. Dr. Bulent Tarcan
Sok. No: 5/1
Gayrettepe ISTANBUL 34349 / TR
02 / SELAMOGLU, Mehmet Levent
Pak Is Merkezi Prof. Dr. Bulent Tarcan
Sok. No: 5/1
Gayrettepe ISTANBUL 34349 / TR
03 / PAK, Nevhiz
Pak Is Merkezi Prof. Dr. Bulent Tarcan
Sok. No: 5/1
Gayrettepe ISTANBUL 34349 / TR
04 / BINGOL, Semra
Pak Is Merkezi Prof. Dr. Bulent Tarcan
Sok. No: 5/1
Gayrettepe ISTANBUL 34349 / TR
 [2011/43]
Representative(s)Kodron, Felix
Rechtsanwalt Postfach 2649
55016 Mainz / DE
[2011/43]
Application number, filing date08807092.516.09.2008
WO2008IB02412
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010032073
Date:25.03.2010
Language:EN
[2010/12]
Type: A1 Application with search report 
No.:EP2379066
Date:26.10.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 25.03.2010 takes the place of the publication of the European patent application.
[2011/43]
Type: B1 Patent specification 
No.:EP2379066
Date:26.03.2014
Language:EN
[2014/13]
Search report(s)International search report - published on:EP25.03.2010
ClassificationIPC:A61K31/485, A61P27/02
[2013/02]
CPC:
A61K31/00 (EP,US); A61K31/485 (EP,US); A61K9/0048 (EP,US);
A61P27/00 (EP); A61P27/02 (EP)
Former IPC [2011/43]A61K31/00, A61K31/485, A61P27/02
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2014/13]
Extension statesALNot yet paid
BANot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:VERWENDUNG VON OPIOID ANTGONISTEN ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR BEHANDLUNG VON DEGENERATIVEN NETZHAUTERKRANKUNGEN[2013/02]
English:USE OF OPIOID ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT IN THE TREATMENT OF RETINAL DEGENERATIVE DISEASES[2011/43]
French:UTILISATION D'ANTAGONISTES DES OPIACÉS POUR LA PRÉPARATION D'UN MÉDICAMENT DANS LE TRAITEMENT DE MALADIES DÉGÉNÉRATIVES DE LA RÉTINE[2014/04]
Former [2011/43]VERWENDUNG VON OPIOID-ANTAGONISTEN ZUR HERSTELLUNG EINES MEDIKAMENTS ZUR BEHANDLUNG VON DEGENERATIVEN NETZHAUTERKRANKUNGEN
Former [2011/43]UTILISATION D ANTAGONISTES DES OPIACÉS POUR LA PRÉPARATION D UN MÉDICAMENT DANS LE TRAITEMENT DE MALADIES DÉGÉNÉRATIVES DE LA RÉTINE
Entry into regional phase30.05.2011National basic fee paid 
30.05.2011Designation fee(s) paid 
30.05.2011Examination fee paid 
Examination procedure30.05.2011Examination requested  [2011/43]
13.12.2011Amendment by applicant (claims and/or description)
09.05.2012Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time
31.01.2013Communication of intention to grant the patent
10.04.2013Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
26.04.2013Fee for grant paid
26.04.2013Fee for publishing/printing paid
02.01.2014Communication of intention to grant the patent
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  31.01.2013
Opposition(s)06.01.2015No opposition filed within time limit [2015/10]
Request for further processing for:The application is deemed to be withdrawn due to non-payment of the filing fee
30.05.2011Request for further processing filed
30.05.2011Full payment received (date of receipt of payment)
Request granted
14.06.2011Decision despatched
The application is deemed to be withdrawn due to non-payment of the examination fee
30.05.2011Request for further processing filed
30.05.2011Full payment received (date of receipt of payment)
Request granted
14.06.2011Decision despatched
The application is deemed to be withdrawn due to non-payment of designation fees
TR, SK, SI, SE, RO, PT, PL, NO, NL, MT, MC, LV, LU, LT, IT, IS, IE, HU, HR, GR, GB, FR, FI, ES, EE, DK, DE, CZ, CY, CH, BG, BE, AT
30.05.2011Request for further processing filed
30.05.2011Full payment received (date of receipt of payment)
Request granted
14.06.2011Decision despatched
Fees paidRenewal fee
08.08.2011Renewal fee patent year 03
14.05.2012Renewal fee patent year 04
13.09.2012Renewal fee patent year 05
20.08.2013Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
16.04.201103   M06   Fee paid on   08.08.2011
30.09.201104   M06   Fee paid on   14.05.2012
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Former [2016/33]TR26.03.2014
Cited inInternational search[X]   NI YING-QIN ET AL: "Neuroprotective effects of naloxone against light-induced photoreceptor degeneration through inhibiting retinal microglial activation", IOVS, vol. 49, no. 6, June 2008 (2008-06-01), pages 2589 - 2598, XP002550374, ISSN: 0146-0404 [X] 1,3 * page 2594, column R - page 2597, column L *

DOI:   http://dx.doi.org/10.1167/iovs.07-1173
 [A]   LAM TIM T ET AL: "The effects of naloxone on retinal ischemia in rats", JOURNAL OF OCULAR PHARMACOLOGY, MARY ANN LIEBERT, INC. NEW YORK, NY, US, vol. 10, no. 2, 1 January 1994 (1994-01-01), pages 481 - 492, XP009124102, ISSN: 8756-3320 [A] 1-12 * abstract *

DOI:   http://dx.doi.org/10.1089/jop.1994.10.481
 [A]   ZAGON ET AL: "Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium", BRAIN RESEARCH BULLETIN, ELSEVIER SCIENCE LTD, OXFORD, GB, vol. 72, no. 1, 13 February 2007 (2007-02-13), pages 18 - 24, XP005885659, ISSN: 0361-9230 [A] 1-12 * abstract *

DOI:   http://dx.doi.org/10.1016/j.brainresbull.2006.12.007
 [A]   FISCHER A J ET AL: "OPIATE AND N-METHYL-D-ASPARTATE RECEPTORS IN FORM-DEPRIVATION MYOPIA", VISUAL NEUROSCIENCE, CAMBRIDGE UNIVERSITY PRESS, GB, vol. 15, no. 6, 1 November 1998 (1998-11-01), pages 1089 - 1096, XP009024602, ISSN: 0952-5238 [A] 1-12 * page 1092 *

DOI:   http://dx.doi.org/10.1017/S0952523898156080
 [A]   GUPTA KALPNA ET AL: "Morphine exaggerates retinopathy in transgenic sickle mice.", BLOOD, vol. 106, no. 11, Part 1, November 2005 (2005-11-01), & 47TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ATLANTA, GA, USA; DECEMBER 10 -13, 2005, pages 64A - 65A, XP002550375, ISSN: 0006-4971 [A] 1-12 * abstract *
 [A]   COOK H L ET AL: "Age-related macular degeneration: diagnosis and management", BRITISH MEDICAL BULLETIN, vol. 85, March 2008 (2008-03-01), pages 127 - 149, XP002550376, ISSN: 0007-1420 [A] 1-12 * table 1 *

DOI:   http://dx.doi.org/10.1093/bmb/ldn012
 [A]   DELYFER MARIE-NOELLE ET AL: "Inherited retinal degenerations: therapeutic prospects", BIOLOGY OF THE CELL (PARIS), vol. 96, no. 4, May 2004 (2004-05-01), pages 261 - 269, XP002550377, ISSN: 0248-4900 [A] 1-12 * page 263, column L - page 265 *

DOI:   http://dx.doi.org/10.1016/J.BIOLCEL.2004.01.006
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