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Extract from the Register of European Patents

EP About this file: EP2195462

EP2195462 - PREDICTION OF SLEEP PARAMETER AND RESPONSE TO SLEEP-INDUCING COMPOUND BASED ON PER3 VNTR GENOTYPE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.04.2014
Database last updated on 17.09.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
Vanda Pharmaceuticals Inc.
9605 Medical Center Drive, Suite 300
Rockville, MD 20850 / US
[2013/12]
Former [2010/24]For all designated states
Vanda Pharmaceuticals Inc.
9605 Medical Center Drive, Suite 300
Rockville NY 20850 / US
Inventor(s)01 / LAVEDAN, Christian
22 Eldwick Court
Potomac MD 20854 / US
02 / POLYMEROPOULOS, Mihael H.
11300 Ridge Mist Terrace
Potomac, MD 20854 / US
03 / BIRZNIEKS, Gunther
6321 Tone Court
Bethesda MD 20817 / US
 [2013/09]
Former [2010/24]01 / LAVEDAN, Christian
22 Eldwick Court
Potomac MD 20854 / US
02 / POLYMEROPOULOS, Mihael, H.
11300 RidgeMist Terrace
Potomac MD 20854 / US
03 / BIRZNIEKS, Gunther
6321 Tone Court
Bethesda MD 20817 / US
Representative(s)Schiffer, Axel Martin, et al
Weber & Heim Patentanwälte
Partnerschaftsgesellschaft mbB
Irmgardstrasse 3
81479 München / DE
[N/P]
Former [2013/24]Schiffer, Axel Martin, et al
Weber & Heim Patentanwälte
Irmgardstrasse 3
81479 München / DE
Former [2010/24]Schiffer, Axel Martin, et al
Weber & Heim Patentanwälte Irmgardstrasse 3
81479 München / DE
Application number, filing date08830209.612.09.2008
[2010/24]
WO2008US76147
Priority number, dateUS20070972196P13.09.2007         Original published format: US 972196 P
[2010/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009036257
Date:19.03.2009
Language:EN
[2009/12]
Type: A1 Application with search report 
No.:EP2195462
Date:16.06.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 19.03.2009 takes the place of the publication of the European patent application.
[2010/24]
Type: B1 Patent specification 
No.:EP2195462
Date:12.06.2013
Language:EN
[2013/24]
Search report(s)International search report - published on:EP19.03.2009
ClassificationIPC:C12Q1/68, A61K31/16
[2010/24]
CPC:
C12Q1/6883 (EP,US); A61K31/16 (EP,US); A61P25/00 (EP);
A61P25/20 (EP); A61P43/00 (EP); C07D307/81 (US);
C12Q2600/106 (EP,US); C12Q2600/156 (EP,US); Y10T436/143333 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/24]
TitleGerman:PROGNOSE VON SCHLAFPARAMETERN UND REAKTIONEN AUF EINE SCHLAFFÖRDERNDE VERBINDUNG AUF BASIS DES GENOTYPS PER3 VNTR[2010/24]
English:PREDICTION OF SLEEP PARAMETER AND RESPONSE TO SLEEP-INDUCING COMPOUND BASED ON PER3 VNTR GENOTYPE[2010/24]
French:PRÉVISION D'UN PARAMÈTRE DU SOMMEIL ET DE LA RÉPONSE À UN COMPOSÉ INDUISANT LE SOMMEIL À BASE DU GÉNOTYPE DU MINISATELLITE (VNTR) PER3[2010/24]
Entry into regional phase24.03.2010National basic fee paid 
24.03.2010Designation fee(s) paid 
24.03.2010Examination fee paid 
Examination procedure24.03.2010Examination requested  [2010/24]
02.06.2010Amendment by applicant (claims and/or description)
06.08.2010Despatch of a communication from the examining division (Time limit: M04)
16.12.2010Reply to a communication from the examining division
10.11.2011Despatch of a communication from the examining division (Time limit: M04)
19.03.2012Reply to a communication from the examining division
11.01.2013Communication of intention to grant the patent
29.04.2013Fee for grant paid
29.04.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.08.2010
Opposition(s)13.03.2014No opposition filed within time limit [2014/21]
Fees paidRenewal fee
27.09.2010Renewal fee patent year 03
26.09.2011Renewal fee patent year 04
25.09.2012Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.09.2008
AT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
MT12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
TR12.06.2013
BG12.09.2013
GB12.09.2013
IE12.09.2013
LU12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
CH30.09.2013
FR30.09.2013
LI30.09.2013
IS12.10.2013
PT14.10.2013
[2015/34]
Former [2015/32]AT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
MT12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
TR12.06.2013
BG12.09.2013
GB12.09.2013
IE12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
CH30.09.2013
FR30.09.2013
LI30.09.2013
IS12.10.2013
PT14.10.2013
Former [2015/30]AT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GB12.09.2013
IE12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
CH30.09.2013
FR30.09.2013
LI30.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/37]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GB12.09.2013
IE12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
CH30.09.2013
FR30.09.2013
LI30.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/34]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GB12.09.2013
IE12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
CH30.09.2013
LI30.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/33]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
IE12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/24]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/21]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/20]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/14]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/11]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/10]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/09]AT12.06.2013
BE12.06.2013
EE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
PT14.10.2013
Former [2014/08]BE12.06.2013
FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
PT14.10.2013
Former [2014/02]FI12.06.2013
HR12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/51]FI12.06.2013
HR12.06.2013
LT12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/50]FI12.06.2013
LT12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/49]FI12.06.2013
LT12.06.2013
SE12.06.2013
SI12.06.2013
NO12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/48]LT12.06.2013
NO12.09.2013
ES23.09.2013
Former [2013/47]LT12.06.2013
NO12.09.2013
Cited inInternational search[XY]WO2004038043  (UNIV SURREY [GB], et al) [X] 1,3-5,10,11 * the whole document * * page 3 - page 4 * * page 9 - page 11; figure 1; claims 1-8 * * claims 22-32 * [Y] 12-18;
 [Y]WO2005063297  (SEPRACOR INC [US], et al) [Y] 12-18 * the whole document *;
 [PA]WO2007137244  (VANDA PHARMACEUTICALS INC [US], et al) [PA] * the whole document *;
 [A]  - ARCHER S N ET AL, "A length polymorphism in the circadian clock gene PER3 is linked to delayed sleep syndrome and extreme diurnal preference", SLEEP, ALLEN PRESS, LAWRENCE, KS, US, (20030615), vol. 26, no. 4, ISSN 0161-8105, pages 4134 - 15, XP008029828 [A] * the whole document *
 [A]  - VIOLA ET AL, "PER3 Polymorphism Predicts Sleep Structure and Waking Performance", CURRENT BIOLOGY, CURRENT SCIENCE, GB, (20070402), vol. 17, no. 7, ISSN 0960-9822, pages 613 - 618, XP022009295 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/j.cub.2007.01.073
 [A]  - EBISAWA T ET AL, "ASSOCIATION OF STRUCTURAL POLYMORPHISMS IN THE HUMAN PERIOD3 GENE WITH DELAYED SLEEP PHASE SYNDROME", EMBO REPORTS, (20010101), vol. 2, no. 4, pages 342 - 346, XP001187591 [A] * the whole document *

DOI:   http://dx.doi.org/10.1093/embo-reports/kve070
 [DY]  - NIMISH N VACHHARAJANI ET AL, "PRECLINICAL PHARMACOKINETICS AND METABOLISM OF BMS-214778, A NOVEL MELATONIN RECEPTOR AGONIST", JOURNAL OF PHARMACEUTICAL SCIENCE,, (20030401), vol. 92, no. 4, ISSN 0022-3549, pages 760 - 772, XP008074135 [DY] 12-18 * the whole document *

DOI:   http://dx.doi.org/10.1002/jps.10348
 [A]  - RAJARATNAM S M ET AL, "The melatonin agonist VEC-162 immediately phase-advances the human circadian system", SLEEP (ROCHESTER), & 20TH ANNUAL MEETING OF THE ASSOCIATED-PROFESSIONAL-SLEEP-SOCIETIES; SALT LAKE CITY, UT, USA; JUNE 17 -22, 2006, (2006), vol. 29, no. Suppl. S, ISSN 0161-8105, page A54, XP008098612 [A] * abstract *
 [PA]  - BIRZNIEKS G ET AL, "Melatonin agonist VEC-162 improves sleep onset and maintenance in a model of transient insomnia", SLEEP (ROCHESTER), & 21ST ANNUAL MEETING OF THE ASSOCIATION-PROFESSIONAL-SLEEP-SOCIETIES; MINNEAPOLIS, MN, USA; JUNE 09 -14, 2007, (2007), vol. 30, no. Suppl. S, ISSN 0161-8105, page A264, XP008098611 [PA] * abstract *
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