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EP2194987
European procedure
Extract from the Register of European Patents
EP About this file: EP2194987
| EP2194987 - NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 24.03.2017 Database last updated on 08.10.2024 | Most recent event Tooltip | 24.03.2017 | No opposition filed within time limit | published on 26.04.2017 [2017/17] | Applicant(s) | For all designated states Boston Biomedical, Inc. 640 Memorial Drive Cambridge, MA 02139 / US | [2016/06] |
| Former [2010/24] | For all designated states Boston Biomedical, Inc. 333 Providence Highway Norwood, MA 02062 / US | Inventor(s) | 01 /
JIANG, Zhiwei 27 Kettle Plain Road Stow MA 01775 / US | 02 /
LI, Chiang, Jia Unit 1606 8 Museum Way Cambridge, MA 02141 / US | 03 /
LI, Wei 18 Oak Street Wayland MA 01778 / US | 04 /
LEGGETT, David 5 Lincoln Street Milton MA 02186 / US | [2016/20] |
| Former [2010/24] | 01 /
JIANG, Zhiwei 27 Kettle Plain Road Stow MA 01775 / US | ||
| 02 /
LI, Chiang, Jia Unit 1606 8 Museum Way Cambridge, MA 02141 / US | |||
| 03 /
LI, Wei 18 Oak Street Wayland MA 01778 / US | |||
| 04 /
LEGGETT, David 5 Lincoln Street Milton MA 02186 / US | Representative(s) | Finnie, Isobel Lara, et al Haseltine Lake LLP Lincoln House, 5th Floor 300 High Holborn London WC1V 7JH / GB | [2016/20] |
| Former [2013/15] | Mintz Levin Cohn Ferris Glovsky and Popeo LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | ||
| Former [2011/51] | Rands, Peter David, et al Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | ||
| Former [2010/24] | Viering, Jentschura & Partner Grillparzerstrasse 14 81675 München / DE | Application number, filing date | 08830471.2 | 10.09.2008 | [2010/24] | WO2008US75848 | Priority number, date | US20070971144P | 10.09.2007 Original published format: US 971144 P | US20070013372 | 13.12.2007 Original published format: US 13372 | [2010/24] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2009036059 | Date: | 19.03.2009 | Language: | EN | [2009/12] | Type: | A2 Application without search report | No.: | EP2194987 | Date: | 16.06.2010 | Language: | EN | The application published by WIPO in one of the EPO official languages on 19.03.2009 takes the place of the publication of the European patent application. | [2010/24] | Type: | B1 Patent specification | No.: | EP2194987 | Date: | 18.05.2016 | Language: | EN | [2016/20] | Search report(s) | International search report - published on: | KR | 02.07.2009 | (Supplementary) European search report - dispatched on: | EP | 03.11.2011 | Classification | IPC: | A61K31/505, A61K31/55, A61K38/17 | [2010/24] | CPC: |
C07D307/92 (EP,US);
A61K31/343 (CN,US);
A61K31/38 (EP,US);
A61K47/24 (CN);
A61K47/42 (CN);
A61K47/44 (CN);
A61P1/00 (EP);
A61P1/04 (EP);
A61P11/06 (EP);
A61P17/02 (EP);
A61P17/06 (EP);
A61P17/12 (EP);
A61P19/02 (EP);
A61P25/00 (EP);
A61P25/02 (EP);
A61P25/28 (EP);
A61P29/00 (EP);
A61P31/00 (EP);
A61P35/00 (EP,US);
A61P35/02 (EP);
A61P35/04 (EP);
A61P37/00 (EP);
A61P37/02 (EP);
A61P37/06 (EP);
A61P37/08 (EP);
A61P43/00 (EP);
A61P7/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07D333/74 (EP,US);
Y02A50/30 (EP,US)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2016/20] |
| Former [2010/24] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR | Extension states | AL | Not yet paid | BA | Not yet paid | MK | Not yet paid | RS | Not yet paid | Title | German: | NEUE STAT3-PFAD-HEMMER UND KREBS-STAMMZELL-HEMMER | [2010/24] | English: | NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS | [2010/24] | French: | NOUVEAUX INHIBITEURS DE LA VOIE STAT3 ET NOUVEAUX INHIBITEURS DE CELLULES SOUCHES CANCÉREUSES | [2010/24] | Entry into regional phase | 30.03.2010 | National basic fee paid | 30.03.2010 | Search fee paid | 30.03.2010 | Designation fee(s) paid | 30.03.2010 | Examination fee paid | Examination procedure | 30.03.2010 | Examination requested [2010/24] | 21.09.2012 | Amendment by applicant (claims and/or description) | 16.09.2013 | Despatch of a communication from the examining division (Time limit: M06) | 22.04.2014 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 26.06.2014 | Reply to a communication from the examining division | 26.03.2015 | Despatch of a communication from the examining division (Time limit: M04) | 29.06.2015 | Reply to a communication from the examining division | 21.09.2015 | Communication of intention to grant the patent | 25.01.2016 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 25.01.2016 | Fee for grant paid | 25.01.2016 | Fee for publishing/printing paid | 18.03.2016 | Communication of intention to grant the patent | 12.04.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | EP16156290.5 / EP3058941 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 16.09.2013 | Opposition(s) | 21.02.2017 | No opposition filed within time limit [2017/17] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 26.06.2014 | Request for further processing filed | 26.06.2014 | Full payment received (date of receipt of payment) Request granted | 10.07.2014 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 21.09.2012 | Request for further processing filed | 21.09.2012 | Full payment received (date of receipt of payment) Request granted | 01.10.2012 | Decision despatched | Fees paid | Renewal fee | 30.09.2010 | Renewal fee patent year 03 | 30.09.2011 | Renewal fee patent year 04 | 25.09.2012 | Renewal fee patent year 05 | 27.09.2013 | Renewal fee patent year 06 | 26.09.2014 | Renewal fee patent year 07 | 28.09.2015 | Renewal fee patent year 08 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | EP0466094 [ ] (CANON KK [JP]); | JPH1165141 [ ] (CANON KK); | [X]WO9962909 (UNIV NORTH CAROLINA [US], et al) [X] 14,15 * claim 12 * * pages 6,11 * * pages 19-20,27 * * page 9 *; | [X]WO2004026253 (MULLER KLAUS [DE], et al) [X] 14,15 * claim - * * pages 4,9-10 * * pages 19,22 * * pages 24-25 *; | [XP]EP1860103 (TAHEEBO JAPAN CO LTD [JP]) [XP] 14,15 * claim 17 *; | [X] - CHEN, CHENG CHANG ET AL, "Constituents of Markhamia hildebrandtii (Baker) Sprague and their antitumor activity", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1986:568912, URL: STN, XP002661423 [X] 7,11-15 * abstract * | [X] - GAFNER S ET AL, "ANTIFUNGAL AND ANTIBACTERIAL NAPHTOQUINONES FROM NEWBOULDIA LAEVIS ROOTS", PHYTOCHEMISTRY, PERGAMON PRESS, GB, (19960101), vol. 42, no. 5, doi:10.1016/0031-9422(96)00135-5, ISSN 0031-9422, pages 1315 - 1320, XP001026085 [X] 7,11 * table 3; compounds 1-10 * DOI: http://dx.doi.org/10.1016/0031-9422(96)00135-5 | [X] - GORMANN R ET AL, "Furanonaphthoquinones, atraric acid and a benzofuran from the stem barks of Newbouldia laevis", PHYTOCHEMISTRY, PERGAMON PRESS, GB, (20040101), vol. 64, no. 2, doi:10.1016/S0031-9422(03)00277-2, ISSN 0031-9422, pages 583 - 587, XP004448678 [X] 7,11 * compounds 3-5 * DOI: http://dx.doi.org/10.1016/S0031-9422(03)00277-2 | [X] - KIKUCHI, TOSHIHIRO ET AL, "Electrophotographic photosensitive member", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1992:245248, URL: STN, XP002661424 [X] 7,11 * abstract * | [X] - MARUYAMA, AKIO ET AL, "Electrophotographic photoreceptor, process cartridge and electrophotographic apparatus using same", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1999:157137, URL: STN, XP002661425 [X] 7,11 * abstract * | [X] - KOBAYASHI, KAZUHIRO ET AL, "An improved method for the preparation of 4,7-dioxo-4,7-dihydrobenzo[b]thiophene-2-carboxylates from 2-acyl-1,4-benzoquinones and mercaptoacetates", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2002:33229, URL: STN, XP002661426 [X] 1,2,11 * abstract * | [X] - OGAWA MASAYUKI ET AL, "Cytotoxic activity toward KB cells of 2-substituted naphtho[2,3-b]furan-4,9-diones and their related compounds", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, (200604), vol. 70, no. 4, ISSN 0916-8451, pages 1009 - 1012, XP002661427 [X] 14,15 * table 2 * DOI: http://dx.doi.org/10.1271/bbb.70.1009 | [X] - ITOIGAWA M ET AL, "CANCER CHEMOPREVENTIVE ACTIVITY OF NAPHTHOQUINONES AND THEIR ANALOGS FROM AVICENNIA PLANTS", CANCER LETTERS, NEW YORK, NY, US, (20011228), vol. 174, no. 2, doi:10.1016/S0304-3835(01)00707-8, ISSN 0304-3835, pages 135 - 139, XP008047525 [X] 14,15 * pages 136-137 * DOI: http://dx.doi.org/10.1016/S0304-3835(01)00707-8 | [X] - WILLIAMS RUSSELL B ET AL, "Two new cytotoxic naphthoquinones from Mendoncia cowanii from the rainforest of Madagascar", PLANTA MEDICA, (200605), vol. 72, no. 6, ISSN 0032-0943, pages 564 - 566, XP002661428 [X] 14,15 * page 565 * DOI: http://dx.doi.org/10.1055/S-2006-931554 | [X] - DESMOND JULIAN C ET AL, "The synthetic furanonaphthoquinone induces growth arrest, apoptosis and differentiation in a variety of leukaemias and multiple myeloma cells", BRITISH JOURNAL OF HAEMATOLOGY, (200511), vol. 131, no. 4, ISSN 0007-1048, pages 520 - 529, XP002661429 [X] 14,15 * page 528 * DOI: http://dx.doi.org/10.1111/J.1365-2141.2005.05803.X | [A] - SONG HUI ET AL, "A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (200503), vol. 102, no. 13, ISSN 0027-8424, pages 4700 - 4705, XP002661430 [A] 1-15 * abstract * DOI: http://dx.doi.org/10.1073/PNAS.0409894102 | [A] - YAO ET AL., "Experimental study on the growth inhibition of bladder cancer cells by signal conduction blocker AG490", JOURNAL OF CLINICAL UROLOGY, (200605), vol. 21, no. 5, pages 380 - 382, XP002661431 [A] 1-15 * abstract * | International search | [X]US6337346 (LEE KUO-HSIUNG [US], et al); | [A]US6828337 (BELLONI PAULA NANETTE [US], et al); | [X] - SERGIO R. PERAZA-SNCHEZ ET AL., "Cytotoxic Constituents of the Roots ofEkmanianthe longiflora", JOURNAL OF NATURAL PRODUCTS, (2000), vol. 63, pages 492 - 495, XP008132280 DOI: http://dx.doi.org/10.1021/np990528l |