-
EP2195017
European procedure
Extract from the Register of European Patents
EP About this file: EP2195017
| EP2195017 - HUMAN ANTIBODIES THAT BIND MESOTHELIN, AND USES THEREOF [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 28.08.2015 Database last updated on 18.11.2024 | Most recent event Tooltip | 28.08.2015 | No opposition filed within time limit | published on 30.09.2015 [2015/40] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [N/P] |
| Former [2014/43] | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08540 / US | ||
| Former [2010/24] | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08540 / US | Inventor(s) | 01 /
TERRETT, Jonathan A. 510 N. Castelrock Terrace Sunnyvale, CA 94087 / US | 02 /
POGUE, Sarah L. 5471 Midday Commons Fremont, CA 94555 / US | 03 /
TOY, Kristopher 521 Cottonwood Drive Milpitas, CA 95035 / US | 04 /
YANG, Lan 18668 Purissima Way Morgan Hill, CA 95037 / US | 05 /
RAO-NAIK, Chetana 565 Matterhorn Drive Walnut Creek, CA 94598 / US | 06 /
CHEN, Bingliang 118 Lawrence Road Alameda, CA 94502 / US | [2014/24] |
| Former [2010/36] | 01 /
TERRETT, Jonathan, A. 510 N. Castelrock Terrace Sunnyvale, CA 94087 / US | ||
| 02 /
POGUE, Sarah, L. 5471 Midday Commons Fremont, CA 94555 / US | |||
| 03 /
TOY, Kristopher 521 Cottonwood Drive Milpitas, CA 95035 / US | |||
| 04 /
YANG, Lan 18668 Purissima Way Morgan Hill, CA 95037 / US | |||
| 05 /
RAO-NAIK, Chetana 565 Matterhorn Drive Walnut Creek, CA 94598 / US | |||
| 06 /
CHEN, Bingliang 118 Lawrence Road Alameda, CA 94502 / US | |||
| Former [2010/27] | 01 /
TERRETT, Jonathan, A. 510 N. Castelrock Terrace Sunnyvale, CA 94087 / US | ||
| 02 /
POGUE, Sarah, L. 5471 Midday Commons Fremont, CA 94555 / US | |||
| 03 /
TOY, Kristopher 1694 Ambergrove Drive San Jose, CA 95131 / US | |||
| 04 /
YANG, Lan 18668 Purissima Way Morgan Hill, CA 95037 / US | |||
| 05 /
RAO-NAIK, Chetana 565 Matterhorn Drive Walnut Creek, CA 94598 / US | |||
| 06 /
CHEN, Bingliang 118 Lawrence Road Alameda, CA 94502 / US | |||
| Former [2010/24] | 01 /
TERRETT, Jonathan, A. 510 N. Castelrock Terrace Sunnyvale CA 94087 / US | ||
| 02 /
POGUE, Sarah, L. 5471 Midday Commons Fremont CA 94555 / US | |||
| 03 /
TOY, Kristopher 1694 Ambergrove Drive San Jose CA 95131 / US | |||
| 04 /
YANG, Lan 18668 Purissima Way Morgan Hill CA 95037 / US | |||
| 05 /
RAO-NAIK, Chetana 565 Matterhorn Drive Walnut Creek CA 94598 / US | |||
| 06 /
CHEN, Bingliang 118 Lawrence Road Alameda CA 94502 / US | Representative(s) | Tuxworth, Pamela M. J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | [2013/23] |
| Former [2010/24] | O'Brien, Dominic Paul, et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ / GB | Application number, filing date | 08836490.6 | 29.09.2008 | [2010/24] | WO2008US78123 | Priority number, date | US20070976626P | 01.10.2007 Original published format: US 976626 P | US20070991692P | 30.11.2007 Original published format: US 991692 P | US20080077397P | 01.07.2008 Original published format: US 77397 P | [2010/24] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2009045957 | Date: | 09.04.2009 | Language: | EN | [2009/15] | Type: | A1 Application with search report | No.: | EP2195017 | Date: | 16.06.2010 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.04.2009 takes the place of the publication of the European patent application. | [2010/24] | Type: | B1 Patent specification | No.: | EP2195017 | Date: | 22.10.2014 | Language: | EN | [2014/43] | Search report(s) | International search report - published on: | US | 09.04.2009 | (Supplementary) European search report - dispatched on: | EP | 26.04.2012 | Classification | IPC: | C07K16/30, A61K39/00, C12P21/08, A61P35/00, A61K47/48, A61K39/395 | [2012/21] | CPC: |
C07K16/30 (EP,KR,US);
A61K39/39558 (EP,KR,US);
A61K47/6857 (EP,US);
A61K47/6859 (EP,KR,US);
A61K47/6863 (EP,KR,US);
A61K47/6869 (EP,KR,US);
A61P35/00 (EP);
A61K2039/505 (EP,KR,US);
A61K2300/00 (KR);
C07K2317/21 (EP,KR,US);
C07K2317/41 (EP,KR,US);
C07K2317/565 (EP,KR,US);
C07K2317/73 (EP,KR,US);
C07K2317/732 (EP,KR,US);
C07K2317/76 (EP,KR,US);
| C-Set: |
A61K39/39558, A61K2300/00 (EP,US)
|
| Former IPC [2010/24] | A61K39/00, C12P21/08 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2010/24] | Extension states | RS | 30.03.2010 | Title | German: | MESOTHELIN BINDENDE HUMANE ANTIKÖRPER UND IHRE VERWENDUNG | [2010/24] | English: | HUMAN ANTIBODIES THAT BIND MESOTHELIN, AND USES THEREOF | [2010/24] | French: | ANTICORPS HUMAINS QUI SE LIENT À LA MÉSOTHÉLINE, ET UTILISATIONS DE CEUX-CI | [2010/24] | Entry into regional phase | 30.03.2010 | National basic fee paid | 30.03.2010 | Search fee paid | 30.03.2010 | Designation fee(s) paid | 30.03.2010 | Examination fee paid | Examination procedure | 30.03.2010 | Examination requested [2010/24] | 09.11.2012 | Amendment by applicant (claims and/or description) | 26.03.2013 | Despatch of a communication from the examining division (Time limit: M04) | 30.05.2013 | Reply to a communication from the examining division | 19.05.2014 | Communication of intention to grant the patent | 12.09.2014 | Fee for grant paid | 12.09.2014 | Fee for publishing/printing paid | 12.09.2014 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 26.03.2013 | Opposition(s) | 23.07.2015 | No opposition filed within time limit [2015/40] | Fees paid | Renewal fee | 14.09.2010 | Renewal fee patent year 03 | 29.09.2011 | Renewal fee patent year 04 | 12.09.2012 | Renewal fee patent year 05 | 12.09.2013 | Renewal fee patent year 06 | 12.09.2014 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XI]WO9928471 (US GOV HEALTH & HUMAN SERV [US], et al) [X] 1,7-13 * examples 1,4,5; claims 1-10; table 2 * [I] 2-6,14,15; | [XI]WO2006099141 (MORPHOTEK INC [US], et al) [X] 1,7-13 * examples 1-3; claims 1-44; table 1 * [I] 2-6,14,15; | [XI]WO2006124641 (US GOV HEALTH & HUMAN SERV [US], et al) [X] 1,7-13 * the whole document *[I] 2-6,14,15; | [XYI] - CHANG K ET AL, "CHARACTERIZATION OF THE ANTIGEN (CAK1) RECOGNIZED BY MONOCLONAL ANTIBODY K1 PRESENT ON OVARIAN CANCERS AND NORMAL MES0THELIUM", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER REREARCH, US LNKD- DOI:10.1016/S0065-230X(08)60824-6, (19920101), vol. 52, no. 1, ISSN 0008-5472, pages 181 - 186, XP002038950 [X] 1,7-12 * page 181, column r, paragraph 2 * * page 182, column l, paragraph l - column r, paragraph 1 * * page 184, column r, paragraph 1 * [Y] 14,15 [I] 2-6,14,15 DOI: http://dx.doi.org/10.1016/S0065-230X(08)60824-6 | [XI] - BRINKMANN U ET AL, "Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesothelioma and ovarian cancers", INTERNATIONAL JOURNAL OF CANCER, JOHN WILEY & SONS, INC, UNITED STATES, SWITZERLAND, GERMANY LNKD- DOI:10.1002/(SICI)1097-0215(19970516)71:4<638::AID-IJC21>3.0.CO;2-6, (19970101), vol. 71, no. 4, ISSN 0020-7136, pages 638 - 644, XP002102002 [X] 1,8-12 * abstract * * page 642, column r, paragraph 3; table I * [I] 2,7,13-15 DOI: http://dx.doi.org/10.1002/(SICI)1097-0215(19970516)71:4<638::AID-IJC21>3.0.CO;2-6 | [XI] - LI QIAN ET AL, "CYTOTOXIC ACTIVITY OF THE RECOMBINANT ANTI-MESOTHELIN IMMUNOTOXIN, SS1(DSFV)PE38, TOWARDS TUMOR CELL LINES ESTABLISHED FROM ASCITES OF PATIENTS WITH PERITONEAL MESOTHELIOMAS", ANTICANCER RESEARCH, INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH, GR, (20040501), vol. 24, no. 3A, ISSN 0250-7005, pages 1327 - 1335, XP009076010 [X] 1,7-13 * page 1328, column l, paragraph 2 * * page 1331, column l, paragraph 3 - paragraph 5 * * page 1331, column r, paragraph 2 * * page 1333, column r, paragraph l - page 1334, column l, paragraph 1 * [I] 2-6,14,15 | [XI] - HASSAN R ET AL, "ANTI-TUMOR ACTIVITY OF K1-LYSPE38QQR, AN IMMUNOTOXIN TARGETING MESOTHELIN, A CELL-SURFACE ANTIGEN OVEREXPRESSED IN OVARIAN CANCER AND MALIGNANT MESOTHELIOMA", JOURNAL OF IMMUNOTHERAPY: WITH EMPHASIS ON TUMOR IMMUNOLOGY, RAVEN PRESS, US, (20000701), vol. 23, no. 4, ISSN 1067-5583, pages 473 - 479, XP009076028 [X] 1,7-13 * page 474, column l, paragraph 3 * * page 275, column l, paragraph 2 - paragraph 3 * * page 476, column r, paragraph 1 * [I] 2-6,14,15 | [XI] - CHOWDHURY P S ET AL, "Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 20 JAN 1998 LNKD- PUBMED:9435250, (19980120), vol. 95, no. 2, ISSN 0027-8424, pages 669 - 674, XP002606066 [X] 1,7-13 * paragraph [results]; table 2 * * page 673, column l, paragraph l - column r, paragraph 1 * [I] 2-6,14,15 DOI: http://dx.doi.org/10.1073/pnas.95.2.669 | [XI] - NICOLAIDES NICHOLAS C ET AL, "MORAb-009, a monoclonal antibody that specifically targets mesothelin, a cell surface tumor adhesion molecule over-expressed in pancreatic, ovarian, and lung cancer and mesothelioma", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20070418), vol. 48, ISSN 0197-016X, pages 156 - 157, XP001539268 [X] 1,8-12 * abstract * [I] 2-7,13-15 | [Y] - SHEEHAN PETER F J ET AL, "EFFECTS OF HISTAMINE AND 5-HYDROXYTRYPTAMINE ON THE GROWTH RATE OF XENOGRAFTED HUMAN BRONCHOGENIC CARCINOMAS", EXPERIMENTAL AND CLINICAL PHARMACOLOGY - EKSPERIMENTAL'NAA IKLINICESKAA FARMACOLOGIA, MOSCOW, (19960101), vol. 23, no. 6-7, ISSN 0869-2092, pages 465 - 471, XP008074583 [Y] 14,15 * the whole document * | International search | [Y]US2003040044 (HEAVNER GEORGE [US], et al); | [X]US2006204506 (EBEL WOLFGANG [US], et al) | Examination | WO2009068204 | - GUBBELS JENNIFER AA ET AL, "Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors", MOLECULAR CANCER, BIOMED CENTRAL, LONDON, GB, (20061026), vol. 5, no. 1, doi:10.1186/1476-4598-5-50, ISSN 1476-4598, page 50, XP021024365 DOI: http://dx.doi.org/10.1186/1476-4598-5-50 | - HASSAN RAFFIT ET AL, "Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapy.", LUNG CANCER (AMSTERDAM, NETHERLANDS) JUN 2010, (201006), vol. 68, no. 3, ISSN 1872-8332, pages 455 - 459 | by applicant | WO9928471 | WO2006099141 | WO2008083312 | - RUMP, A. ET AL., J. BIOL. CHEM., (2004), vol. 279, pages 9190 - 9198 | - GUBBELS, J.A. ET AL., MOL. CANCER, (2006), vol. 5, page 50 | - CHANG ET AL., CANCER RESEARCH, (1992), vol. 52, pages 181 - 186 | - BRINKMAN ET AL., INT. J. CANCER, (1997), vol. 71, pages 638 - 644 | - LI ET AL., ANTICANCER RESEARCH, (2004), vol. 24, pages 1327 - 1335 | - HASSAN ET AL., J. IMMUNOTHERAPY, (2000), vol. 23, no. 4, pages 473 - 479 | - CHOWDHURY ET AL., PNAS USA, (1998), vol. 95, pages 669 - 674 | - NICHOLAIDES ET AL., PROC AM. ASS. FOR CANCER RES., (2007), vol. 48, pages 156 - 157 |