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Extract from the Register of European Patents

EP About this file: EP2227545

EP2227545 - MODULATION OF FACTOR 7 EXPRESSION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.03.2016
Database last updated on 11.09.2024
Most recent event   Tooltip25.03.2016Application deemed to be withdrawnpublished on 27.04.2016  [2016/17]
Applicant(s)For all designated states
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[2016/07]
Former [2011/39]For all designated states
Isis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
Former [2010/37]For all designated states
Isis Pharmaceuticals, Inc.
1896 Rutherford Road
Carlsbad, CA 92008 / US
Inventor(s)01 / FREIER, Susan, M.
2946 Renault Street
San Diego, CA 92122 / US
02 / MONIA, Brett, P.
2306 Casa Hermosa Court
Encinitas, CA 92024 / US
03 / ZHANG, Hong
3339 Cadencia St.
Carlsbad, CA 92009 / US
04 / CROSBY, Jeffrey, R.
2292 B Chinquapin Avenue
Carlsbad, CA 92008 / US
05 / ZHAO, Chenguang
5809 Brittany Forrest Lane
San Diego, CA 92130 / US
 [2010/37]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2010/37]Carpmaels & Ransford
One Southampton Row London
WC1B 5HA / GB
Application number, filing date08847806.005.11.2008
[2010/37]
WO2008US82526
Priority number, dateUS20070986928P09.11.2007         Original published format: US 986928 P
[2010/37]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009061851
Date:14.05.2009
Language:EN
[2009/20]
Type: A2 Application without search report 
No.:EP2227545
Date:15.09.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 14.05.2009 takes the place of the publication of the European patent application.
[2010/37]
Search report(s)International search report - published on:EP16.07.2009
ClassificationIPC:C12N15/11, A61K31/7088, A61P7/02
[2010/37]
CPC:
C12N15/1137 (EP,US); A61P11/00 (EP); A61P29/00 (EP);
A61P35/00 (EP); A61P7/02 (EP); A61P9/00 (EP);
A61P9/14 (EP); C12Y304/21021 (EP,US); C12N2310/11 (EP,US);
C12N2310/315 (EP,US); C12N2310/321 (EP,US); C12N2310/3341 (EP,US);
C12N2310/341 (EP,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/37]
TitleGerman:MODULATION DER EXPRESSION VON FAKTOR 7[2010/37]
English:MODULATION OF FACTOR 7 EXPRESSION[2010/37]
French:MODULATION DE L'EXPRESSION DU FACTEUR 7[2010/37]
Entry into regional phase09.06.2010National basic fee paid 
09.06.2010Designation fee(s) paid 
09.06.2010Examination fee paid 
Examination procedure09.06.2010Amendment by applicant (claims and/or description)
09.06.2010Examination requested  [2010/37]
20.09.2013Invitation to indicate the basis for amendments (Time limit: M01)
30.10.2013Reply to an invitation to indicate the basis for amendments
15.11.2013Despatch of a communication from the examining division (Time limit: M06)
23.05.2014Reply to a communication from the examining division
19.09.2014Despatch of a communication from the examining division (Time limit: M06)
30.03.2015Reply to a communication from the examining division
08.07.2015Despatch of a communication from the examining division (Time limit: M04)
19.11.2015Application deemed to be withdrawn, date of legal effect  [2016/17]
16.12.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2016/17]
Divisional application(s)EP15192408.1  / EP3000884
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.11.2013
Fees paidRenewal fee
22.10.2010Renewal fee patent year 03
07.11.2011Renewal fee patent year 04
07.11.2012Renewal fee patent year 05
07.11.2013Renewal fee patent year 06
07.11.2014Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
30.11.201508   M06   Not yet paid
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Cited inInternational search[XY]WO2004016754  (PHARMACIA CORP [US], et al) [X] 19-23,26,27,30,31 * page 135 * * page 24, paragraph 40 * * page 25, paragraph 42; claims 13,17 * * pages 52-53, paragraph 105 * [Y] 28,29;
 [Y]  - BECKER R C ET AL, "NUCLEIC ACID APTAMERS IN THERAPEUTIC ANTICOAGULATION TECHNOLOGY, DEVELOPMENT AND CLINICAL APPLICATION", THROMBOSIS AND HAEMOSTASIS, STUTTGART, DE, (20050601), vol. 93, no. 6, ISSN 0340-6245, pages 1014 - 1020, XP009055852 [Y] 1-18,24,25,32,33 * page 1016, column L, paragraph 2; figure 3 * * page 1014, column R, lines 1-3 *
 [Y]  - SHIRK REBECCA A ET AL, "Inhibitors of Factor VIIa/tissue factor.", ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY SEP 2007, (200709), vol. 27, no. 9, ISSN 1524-4636, pages 1895 - 1900, XP002526314 [Y] 1-18,24,25,28,29,32,33 * abstract * * page 1899, column L, paragraphs 1,2 *

DOI:   http://dx.doi.org/10.1161/ATVBAHA.107.148304
ExaminationWO2004094636
 WO2006020768
    - JOHN MATTHIAS ET AL, "Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE (AND SUPPLEMENTARY INFORMATION), NATURE PUBLISHING GROUP, UNITED KINGDOM, (20071001), vol. 449, no. 7163, doi:10.1038/NATURE06179, ISSN 0028-0836, pages 745 - 748, XP002519570

DOI:   http://dx.doi.org/10.1038/NATURE06179
    - GREG HANNON ET AL, "Small hairpin RNA (shRNA) probe V2HS_83726 for Homo sapiens gene coagulation factor VII (F7)", PROBE, XP002566899
by applicantWO9914226
 US2004171570
 US7399845
 US7427672
 WO2008US64591
 WO2008US68922
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.