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Extract from the Register of European Patents

EP About this file: EP2233495

EP2233495 - GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  03.01.2014
Database last updated on 20.09.2024
Most recent event   Tooltip03.01.2014Application deemed to be withdrawnpublished on 05.02.2014  [2014/06]
Applicant(s)For all designated states
Shionogi & Co., Ltd.
1-8 Doshomachi 3-chome
Chuo-ku
Osaka-shi
Osaka 541-0045 / JP
[N/P]
Former [2010/39]For all designated states
Shionogi & Co., Ltd.
1-8 Doshomachi 3-chome Chuo-ku Osaka-shi
Osaka 541-0045 / JP
Inventor(s)01 / MATSUI, Kouhei
c/o Shionogi&Co. Ltd. 12-4, Sagisu 5-chome Fukushima-ku
Osaka-shi Osaka 553-0002 / JP
02 / MINAGAWA, Kazuyuki
c/o Shionogi&Co. Ltd. 12-4, Sagisu 5-chome Fukushima-ku
Osaka-shi Osaka 553-0002 / JP
03 / YOSHIDA, Osamu
c/o Shionogi&Co. Ltd. 12-4, Sagisu 5-chome Fukushima-ku
Osaka-shi Osaka 553-0002 / JP
04 / MORIMOTO, Kenji
c/o Shionogi&Co. Ltd. 1-1, Futabacho 3-chome
Toyonaka-shi Osaka 561-0825 / JP
05 / OGATA, Yuuki
c/o Shionogi&Co. Ltd. 12-4, Sagisu 5-chome Fukushima-ku
Osaka-shi Osaka 553-0002 / JP
 [2010/39]
Representative(s)Webster, Jeremy Mark, et al
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2010/39]Webster, Jeremy Mark, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date08863497.725.12.2008
[2010/39]
WO2008JP73511
Priority number, dateJP2007033340826.12.2007         Original published format: JP 2007333408
[2010/39]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009081958
Date:02.07.2009
Language:JA
[2009/27]
Type: A1 Application with search report 
No.:EP2233495
Date:29.09.2010
Language:EN
[2010/39]
Search report(s)International search report - published on:JP02.07.2009
(Supplementary) European search report - dispatched on:EP24.02.2011
ClassificationIPC:C07K9/00, C07G11/00, A61K38/00, A61P9/00, A61P31/04
[2010/39]
CPC:
C07K9/008 (EP,US); A61P11/00 (EP); A61P17/00 (EP);
A61P19/02 (EP); A61P31/04 (EP); A61P9/00 (EP);
A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/39]
Extension statesAL12.07.2010
BA12.07.2010
MK12.07.2010
RS12.07.2010
TitleGerman:ANTIBIOTISCHES GLYKOSILIERTES GLYKOPEPTIDDERIVAT[2010/39]
English:GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVE[2010/39]
French:DÉRIVÉ ANTIBIOTIQUE DE GLYCOPEPTIDE GLYCOSYLÉ[2010/39]
Entry into regional phase13.07.2010Translation filed 
12.07.2010National basic fee paid 
12.07.2010Search fee paid 
12.07.2010Designation fee(s) paid 
12.07.2010Examination fee paid 
Examination procedure13.07.2010Examination requested  [2010/39]
19.09.2011Amendment by applicant (claims and/or description)
23.04.2013Despatch of a communication from the examining division (Time limit: M04)
04.09.2013Application deemed to be withdrawn, date of legal effect  [2014/06]
01.10.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2014/06]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.04.2013
Fees paidRenewal fee
21.12.2010Renewal fee patent year 03
20.12.2011Renewal fee patent year 04
20.12.2012Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[ID]  - RITTER THOMAS K ET AL, "A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin.", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH) 6 OCT 2003 LNKD- PUBMED:14533156, (20031006), vol. 42, no. 38, ISSN 1433-7851, pages 4657 - 4660, XP002620449 [ID] 1-15 * the whole document * * in particular compound 4e and page 4659, first paragraph *

DOI:   http://dx.doi.org/10.1002/anie.200351534
International search[Y]US2004259228  (THORSON JON [US]);
 [Y]WO2006057288  (UNIV NAGOYA NAT UNIV CORP [JP], et al);
 [Y]JP2006503015  (K.U. LEUVEN RESEARCH AND DEVELOPMENT);
 [Y]JP2003026725  (TOYO BOSEKI);
 [A]JPH04108800  (LILLY CO ELI);
 [A]JP2006528188  (THERAVANCE, INC.);
 [A]JP2002520422  (PRINCETON UNIVERSITY);
 [A]JP2007505841  (ALPHARMA APS);
 [A]WO2006057303  (UNIV NAGOYA NAT UNIV CORP [JP], et al);
 [A]WO0181373  (MERCK & CO INC [US]);
 [A]JPH01240196  (SHIONOGI & CO);
 [A]WO0041710  (UNIV PRINCETON [US]);
 [A]WO0181372  (UNIV PRINCETON [US]);
 [A]JP2001163898  (SHIONOGI & CO);
 [A]WO2006003456  (ISIS INNOVATION [GB], et al)
 [Y]  - GRIFFITH B.R. ET AL., "'Sweetening' natural products via glycorandomization", CURRENT OPINION BIOTECHNOLOGY, (2005), vol. 16, doi:doi:10.1016/j.copbio.2005.10.002, pages 622 - 630, XP005173494

DOI:   http://dx.doi.org/10.1016/j.copbio.2005.10.002
 [Y]  - SALAS, J.A ET AL., "Engineering the glycosylation of natural products in actinomycetes", TRENDS IN MICROBIOL., (20070406), vol. 15, no. 5, doi:doi:10.1016/j.tim.2007.03.004, pages 219 - 232, XP022053528

DOI:   http://dx.doi.org/10.1016/j.tim.2007.03.004
 [Y]  - LU.W. ET AL., "Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin", PROC.NATL.ACAD.SCI.USA, (2004), vol. 101, no. 13, pages 4390 - 4395
 [Y]  - OBERTHUER, M. ET AL., "A systematic investigation of the synthetic utility of glycopeptides glycosyltransferases", J.AM.CHEM. SOC., (2005), vol. 127, no. 30, pages 10747 - 10752
 [Y]  - MULICHAK, A.M. ET AL., "Structure of the UDP- glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics", STRUCTURE, (2001), vol. 9, pages 547 - 557
 [A]  - FU, X. ET AL., "Antibiotic optimization via in vitro glycorandomization", NATURE BIOTECH., (2003), vol. 21, no. 12, pages 1467 - 1469
 [A]  - GRDADOLNIK, S.G. ET AL., "Vancomycin: Conformational consequences of the sugar substituent.", J. MEDICINAL CHEM., (1998), vol. 41, pages 2090 - 2099
 [A]  - GRIFFITH, B.R. ET AL., "Model for antibiotic optimization via neoglycosylation: synthesis of liponeoglycopeptides active against VRE.", J.AM. CHEM.SOC., (2007), vol. 129, no. 26, doi:doi:10.1021/ja068602r, pages 8150 - 8155, XP002488143

DOI:   http://dx.doi.org/10.1021/ja068602r
by applicantJPH01240196
 JP2001163898
 WO2006003456
 US2005239689
 US2003068669
 US2004259228
 US2005266523
 WO2004019970
 WO0181373
 WO0181372
 WO0069893
 WO0059528
 WO0042067
 WO0004044
 WO9303060
 EP0301785
 EP0273727
 WO2006057303
 JPS61251699
 JPH07258289
 WO9630401
 WO0039156
 JP2000302687
 WO2004044222
 US4639433
 US4643987
 US4497802
 US4698327
 US5591714
 US5840684
 US5843889
 EP0802199
 EP0801075
 EP0667353
 WO9728812
 WO9738702
 WO9852589
 WO9852592
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    - PROC. NATL. ACAD. SCI. U.S.A., (2004), vol. 101, no. 13, pages 4390 - 4395
    - CHEM. ASIAN. J., (2006), vol. 1, pages 445 - 452
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.