Extract from the Register of European Patents

EP About this file: EP2266619

EP2266619 - PHARMACEUTICAL COMPOSITION BASED ON HEPATOPROTECTOR AND PREBIOTIC, THE PRODUCTION AND USE THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.03.2016
Database last updated on 09.04.2026
Most recent event   Tooltip08.06.2018Lapse of the patent in a contracting state
New state(s): HU
published on 11.07.2018  [2018/28]
Applicant(s)For all designated states
Dikovskiy, Aleksander Vladimirovich
Ul. Aviatsionnaya 79/3-356
Moscow 123182 / RU
[2010/52]
Inventor(s)01 / RUDOY, Boris Anatolievich
ul. Graivoronovskaya 18/3-63
Moscow 109518 / RU
02 / DOROZHKO, Oleg Valentinovich
ul. Akad. Millionschikova 21-15
Moscow 115446 / RU
 [2010/52]
Representative(s)Jeck, Anton
Jeck, Fleck & Partner mbB
Patentanwälte
Klingengasse 2
71665 Vaihingen/Enz / DE
[N/P]
Former [2015/20]Jeck, Anton
Jeck - Fleck - Herrmann
Patentanwälte
Klingengasse 2/1
71665 Vaihingen/Enz / DE
Former [2010/52]Jeck, Anton
Jeck - Fleck - Herrmann Patentanwälte Klingengasse 2/1
71665 Vaihingen/Enz / DE
Application number, filing date08873197.104.03.2008
[2010/52]
WO2008RU00122
Filing languageRU
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2009110816
Date:11.09.2009
Language:RU
[2009/37]
Type: A1 Application with search report 
No.:EP2266619
Date:29.12.2010
Language:DE
[2010/52]
Type: B1 Patent specification 
No.:EP2266619
Date:13.05.2015
Language:DE
[2015/20]
Search report(s)International search report - published on:RU11.09.2009
(Supplementary) European search report - dispatched on:EP17.06.2011
ClassificationIPC:A61K45/06, A61K31/66, A61K31/685, A61K36/28, A61P1/16, A23L1/308, A23L1/30
[2014/47]
CPC:
A61K31/685 (EP,US); A61K31/575 (US); A23L33/10 (EP,US);
A23L33/21 (EP,US); A61K31/52 (US); A61K31/66 (EP,US);
A61K31/7016 (EP,US); A61K31/702 (EP,US); A61K36/28 (EP,US);
A61K45/06 (EP,US); A61K9/0053 (US); A61P1/00 (EP);
A61P1/16 (EP); A23V2002/00 (EP,US) (-)
C-Set:
A61K31/66, A61K2300/00 (EP,US);
A61K31/685, A61K2300/00 (US,EP);
A61K36/28, A61K2300/00 (US,EP);
A23V2002/00, A23V2250/28, A23V2200/3202, A23V2200/32, A23V2250/1842, A23V2250/5046 (US,EP)
Former IPC [2010/52]A61K45/06, A61K31/66, A61K31/685, A61K36/28, A61P1/16
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/20]
Former [2010/52]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNG AUF BASIS EINES LEBERSCHÜTZENDEN MITTELS UND EINES PRÄBIOTISCHEN MITTELS, IHRE HERSTELLUNG UND VERWENDUNG[2010/52]
English:PHARMACEUTICAL COMPOSITION BASED ON HEPATOPROTECTOR AND PREBIOTIC, THE PRODUCTION AND USE THEREOF[2010/52]
French:COMPOSITION PHARMACEUTIQUE À BASE D'HÉPATOPROTECTEUR ET DE PRÉBIOTIQUE, FABRICATION ET UTILISATION DE CELLE-CI[2010/52]
Entry into regional phase28.09.2010Translation filed 
04.10.2010National basic fee paid 
04.10.2010Search fee paid 
04.10.2010Designation fee(s) paid 
04.10.2010Examination fee paid 
Examination procedure04.10.2010Examination requested  [2010/52]
30.10.2010Amendment by applicant (claims and/or description)
29.04.2013Despatch of a communication from the examining division (Time limit: M06)
06.11.2013Reply to a communication from the examining division
21.11.2014Communication of intention to grant the patent
18.03.2015Fee for grant paid
18.03.2015Fee for publishing/printing paid
18.03.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  29.04.2013
Opposition(s)16.02.2016No opposition filed within time limit [2016/16]
Fees paidRenewal fee
04.10.2010Renewal fee patent year 03
31.03.2011Renewal fee patent year 04
31.03.2012Renewal fee patent year 05
02.04.2013Renewal fee patent year 06
31.03.2014Renewal fee patent year 07
31.03.2015Renewal fee patent year 08
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Lapses during opposition  TooltipHU04.03.2008
EE13.05.2015
LT13.05.2015
LV13.05.2015
MC13.05.2015
MT13.05.2015
RO13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
[2018/28]
Former [2017/47]EE13.05.2015
LT13.05.2015
LV13.05.2015
MC13.05.2015
MT13.05.2015
RO13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
Former [2016/50]EE13.05.2015
LT13.05.2015
LV13.05.2015
MC13.05.2015
RO13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
Former [2016/49]EE13.05.2015
LT13.05.2015
LV13.05.2015
MC13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
Former [2016/09]EE13.05.2015
LT13.05.2015
LV13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
Former [2015/51]LT13.05.2015
LV13.05.2015
BG13.08.2015
IS13.09.2015
PT14.09.2015
Former [2015/49]LT13.05.2015
LV13.05.2015
PT14.09.2015
Documents cited:Search[XI] DE102004054133  (NATURPRODUKT CZ SPOL S R O et al.) [X] 1-3,8-13 * paragraphs [0003] - [0008]; example -; claim - *[I] 1-13
 [Y] EP0795604  (CAVALIERE VESELY RENATA MARIA et al.) [Y] 1-13 * page 2, line 3 - line 5 * * page 3, line 17 - line 22; claim - *
 [Y]   KRUEGER K J ET AL: "Nutritional supplements and alternative medicine", CURRENT OPINION IN GASTROENTEROLOGY, GOWER ACADEMIC JOURNALS, LONDON, GB, vol. 20, no. 2, 1 March 2003 (2003-03-01), pages 130 - 138, XP009131865, ISSN: 0267-1379 [Y] 1-13 * page 135, column 2, paragraph 3 - page 136, paragraph 2 *
 [Y]   NEYRINCK AUDREY M ET AL: "Kupffer cell activity is involved in the hepatoprotective effect of dietary oligofructose in rats with endotoxic shock", JOURNAL OF NUTRITION, vol. 134, no. 5, May 2004 (2004-05-01), pages 1124 - 1129, XP002640031, ISSN: 0022-3166 [Y] 1-13 * abstract *
International search[A]   REGISTR LEKARSTVENNYKH SREDSTV ROSSII, 2006, pages 976, 505 - 829, 895
 [A]   KOMPANIYA EVARAL. GEPATRIN (CAPSULY), July 2006 (2006-07-01), Retrieved from the Internet [retrieved on 20081106]
 [A]   INKITIN I.G. ET AL.: "Dyufalak (laktyloza) v lechenyn disbioza kishechnika pri nealkogolnom steatogepatite.", KLINICHESKIE PERSPEKTIVY GASTROENTEROLOGIYA I GEPATOLOGII, vol. 1, 2002, pages 24 - 29
by applicant  HOFMANN A.F.: "Bile acid secretion, bile flow and biliary lipid secretion in humans", HEPATOLOGI., vol. 12, 1990, pages 17S
   MEIER P.J.: "The bile salt secretory polarity of hepatocytes", J. HEPATOL., vol. 9, 1989, pages 124
   G.L. VYSHKOVSKY. M.: "RLS-2006", 2005, article "Verzeichnis der Arzneimittel von Russland. Arzneimittelhandbuch", pages: 895 - 896
   K.G. GUREVICH: "Essentielle Phospholipide bei der Behandlung der Leberkrankheiten", KLINISCHE QUALITTSPRAXIS, 2002, pages 108 - 111
   "Arzneimittelhandbuch", 2005, article "Verzeichnis der Arzneimittel von Russland", pages: 51
   N. M. GRACHEVA: "Hylak forte bei der Komplexbehandlung der Patienten mit akuten Darminfektionen und chronischen Krankheiten des Magen-Darm-Kanals mit Dysbakteriose-Erscheinungen", CONSILIUM MEDICUM, 2004, pages 31 - 34
   V.F. DEMIN: "Erfahrung bei der Anwendung von der bio-phytogenen Korrektur bei Kindern mit Dysbiose", PROBLEME DER MODERNEN KINDERHEILKUNDE, vol. 2, 2003, pages 33 - 36
   S.A. SHEVELEVA: "Probiotika, Prbiotika und probiotische Produkte", STAND VON HEUTE, 1999, pages 33 - 39
   SHOAF L. ET AL.: "Prebiotic galactooligosaccharides reduce adherence of Enteropathogenic Escherichia coli to tissue culture cells", INFECT IMMUN., 18 September 2006 (2006-09-18)
   ZDUNCZYK Z ET AL.: "Physiological effects of lactulose and inulin in the caecum of rats", ARCH ANIM NUTR., vol. 58, no. 1, 2004, pages 89 - 98
   BOUCHNIC Y. ET AL.: "Prospective, randomized Parallel-group trial to evaluate the effects of lactulose and polyethylene glycol-4000 on colonic flora in chronic idiopathic constipation", ALIMENT. PHARMACOL. THER., vol. 19, no. 8, 2004, pages 889 - 899
   I.G. NIKITIN: "Duphalac (Laktulose) bei der Behandlung der Darmdysbiose bei nicht alkoholischer Steatohepatitis. Klinische Aussichten der Gastroenterologie", HEPATOLOGIE, KOLOPROKTOLOGIE, 2002, pages 24 - 29
   V.S. SAVELIEV: "Lipiden-Distress-Syndrom in der Chirurgie", INFORMATIONSBLATT DER MILITRMEDIZINISCHEN AKADEMIE RUSSLANDS, 1999, pages 36 - 39
   "Funktionsstrung der Leber und Dysbiose beim Lipiden-Distress-Syndrom", RMZH, vol. 4, no. 10, 2002, pages 158 - 160
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