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Extract from the Register of European Patents

EP About this file: EP2070535

EP2070535 - Drugs for relieving carbonyl stress and peritoneal dialysates [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.05.2016
Database last updated on 20.09.2024
Most recent event   Tooltip08.12.2017Lapse of the patent in a contracting state
New state(s): LU
published on 10.01.2018  [2018/02]
Applicant(s)For all designated states
Kurokawa, Kiyoshi
Ichigaya Hills 401, 49 Ichigaya-yanagimachi Shinjuku-ku
Tokyo 162-0061 / JP
For all designated states
Miyata, Toshio
20-1-1-43, Sanjomachi
Aoba-ku
Sendai-shi, Miyagi 981-0935 / JP
For all designated states
TOKAI UNIVERSITY EDUCATIONAL SYSTEM
2-28-4 Tomigaya, Shibuya-ku
Tokyo 151-8677 / JP
[2015/16]
Former [2009/25]For all designated states
Kurokawa, Kiyoshi
Ichigaya Hills 401, 49 Ichigaya-yanagimachi Shinjuku-ku
Tokyo 162-0061 / JP
For all designated states
Miyata, Toshio
102 Ekuseru Isehara, 16-25, Sakuradai 2-chome Isehara-shi
Kanagawa 259-1132 / JP
For all designated states
TOKAI UNIVERSITY EDUCATIONAL SYSTEM
2-28-4 Tomigaya, Shibuya-ku
Tokyo 151-8677 / JP
Inventor(s)01 / Toshio, Miyata
20-1-1-43, Sanjomachi, Aoba-ku
Sendai-shi, Miyagi 981-0935 / JP
 [2009/25]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2015/28]
Former [2009/25]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Application number, filing date09002868.923.08.1999
[2009/25]
Priority number, dateJP1998023710824.08.1998         Original published format: JP 23710898
JP1999015539302.06.1999         Original published format: JP 15539399
[2009/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2070535
Date:17.06.2009
Language:EN
[2009/25]
Type: B1 Patent specification 
No.:EP2070535
Date:08.07.2015
Language:EN
[2015/28]
Search report(s)(Supplementary) European search report - dispatched on:EP11.05.2009
ClassificationIPC:A61K31/4415, A61P7/08
[2009/25]
CPC:
A61K31/203 (EP,US); A61K31/44 (KR); A61K31/155 (EP,US);
A61K31/4965 (EP,US); A61K33/00 (EP,US); A61M1/287 (EP,US);
A61P13/12 (EP); A61P43/00 (EP); A61P7/08 (EP) (-)
C-Set:
A61K31/203, A61K2300/00 (EP,US);
A61K31/4965, A61K2300/00 (US,EP);
A61K33/00, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2015/28]
Former [2009/25]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:Wirkstoffe zur Minderung von Carbonylstress und Peritonealdialysaten[2009/25]
English:Drugs for relieving carbonyl stress and peritoneal dialysates[2009/25]
French:Médicaments pour décharger le stress carbonyle et les dialysats péritonéaux[2009/25]
Examination procedure27.02.2009Examination requested  [2009/25]
15.12.2009Amendment by applicant (claims and/or description)
24.01.2011Despatch of a communication from the examining division (Time limit: M04)
31.05.2011Reply to a communication from the examining division
02.10.2012Despatch of a communication from the examining division (Time limit: M06)
14.02.2013Reply to a communication from the examining division
29.11.2013Despatch of a communication from the examining division (Time limit: M01)
12.12.2013Reply to a communication from the examining division
01.12.2014Communication of intention to grant the patent
05.03.2015Fee for grant paid
05.03.2015Fee for publishing/printing paid
05.03.2015Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP99938581.8  / EP1108434
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19990938581) is  17.07.2008
Opposition(s)11.04.2016No opposition filed within time limit [2016/24]
Fees paidRenewal fee
27.02.2009Renewal fee patent year 03
27.02.2009Renewal fee patent year 04
27.02.2009Renewal fee patent year 05
27.02.2009Renewal fee patent year 06
27.02.2009Renewal fee patent year 07
27.02.2009Renewal fee patent year 08
27.02.2009Renewal fee patent year 09
27.02.2009Renewal fee patent year 10
27.02.2009Renewal fee patent year 11
25.08.2010Renewal fee patent year 12
24.08.2011Renewal fee patent year 13
23.08.2012Renewal fee patent year 14
23.08.2013Renewal fee patent year 15
25.08.2014Renewal fee patent year 16
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT08.07.2015
CY08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
NL08.07.2015
SE08.07.2015
IE23.08.2015
LU23.08.2015
BE31.08.2015
CH31.08.2015
LI31.08.2015
FR08.09.2015
GB08.10.2015
GR09.10.2015
PT09.11.2015
DE01.03.2016
[2018/02]
Former [2017/40]AT08.07.2015
CY08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
NL08.07.2015
SE08.07.2015
IE23.08.2015
BE31.08.2015
CH31.08.2015
LI31.08.2015
FR08.09.2015
GB08.10.2015
GR09.10.2015
PT09.11.2015
DE01.03.2016
Former [2016/36]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
SE08.07.2015
IE23.08.2015
CH31.08.2015
LI31.08.2015
FR08.09.2015
GB08.10.2015
GR09.10.2015
PT09.11.2015
DE01.03.2016
Former [2016/34]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
SE08.07.2015
IE23.08.2015
CH31.08.2015
LI31.08.2015
GB08.10.2015
GR09.10.2015
PT09.11.2015
DE01.03.2016
Former [2016/33]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
SE08.07.2015
IE23.08.2015
CH31.08.2015
LI31.08.2015
GR09.10.2015
PT09.11.2015
DE01.03.2016
Former [2016/22]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
SE08.07.2015
CH31.08.2015
LI31.08.2015
GR09.10.2015
PT09.11.2015
Former [2016/21]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/20]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/11]AT08.07.2015
ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/10]ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/09]FI08.07.2015
GR09.10.2015
Documents cited:Search[Y]WO9709981  (UNIV KANSAS MEDICAL CENTER [US]) [Y] 1-11 * claim 13 *;
 [Y]  - LAMB E J ET AL, "IN VITRO FORMATION OF ADVANCED GLYCATION END PRODUCTS IN PERITONEALDIALYSIS FLUID", KIDNEY INTERNATIONAL, NEW YORK, NY, US, (199506), vol. 47, no. 6, ISSN 0085-2538, pages 1768 - 1774, XP000964894 [Y] 1-11 * page 1768, abstract * * page 1769, right-hand column, last paragraph *

DOI:   http://dx.doi.org/10.1038/ki.1995.244
 [Y]  - POSTHUMA NYNKE ET AL, "In vitro advanced glycation and product formation in glucose and icodextrin containing peritoneal dialysis fluids with and without aminoguanidine", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, WILLIAMS AND WILKINS, BALTIMORE, MD, US, (199709), vol. 9, no. Program and Abstr, ISSN 1046-6673, page 270A, XP009095333 [Y] 1-11 * abstract *
 [Y]  - BOOTH A A ET AL, "PYRIDOXAMINE AND THIAMINE PYROPHOSPHATE INHIBIT FORMATION OF ANTIGENIC ANVANCED GLYCATION END PRODUCTS (AGE): COMPARISON WITH AMINOGUANIDINE USING OVERALL AND ISOLATED POST-AMADORI KINETICS", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, US, (19960401), vol. 10, no. 6, ISSN 0892-6638, page A1100, XP000891764 [Y] 1-11 * abstract *
 [Y]  - KHALIFAH R G ET AL, "EFFECTS OF PYRIDOXAMINE, A NOVEL POST-AMADORI AGE INHIBITOR, ON NEPHROPATHY INDUCED BY GLYCATED ALBUMIN", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, WILLIAMS AND WILKINS, BALTIMORE, MD, US, (19970901), vol. 9, no. PROGRAM ABSTR, ISSN 1046-6673, page 641A, XP000965172 [Y] 1-11 * abstract *
 [Y]  - BOOTH A A ET AL, "THIAMINE PYROPHOSPHATE AND PYRIDOXAMINE INHIBIT THE FORMATION OF ANTIGENIC ADVANCED GLYCATION END-PRODUCTS: COMPARISON WITH AMINOGUANIDINE", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (19960101), vol. 220, no. 1, ISSN 0006-291X, pages 113 - 119, XP002024845 [Y] 1-11 * page 113, abstract *

DOI:   http://dx.doi.org/10.1006/bbrc.1996.0366
Examination   - SHINOHARA M ET AL, "OVEREXPRESSION OF GLYOXALASE-I BOVINE ENDOTHELIAL CELLS INHIBITS INTRACELLULAR ADVANCED GLYCATION ENDPRODUCT FORMATION AND PREVENTS HYPERGLYCEMIA-INDUCED INCREASES IN MACROMOLECULAR ENDOCYTOSIS", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US, (19980301), vol. 101, no. 5, doi:10.1172/JCI119885, ISSN 0021-9738, pages 1142 - 1147, XP001005287

DOI:   http://dx.doi.org/10.1172/JCI119885
    - VOZIYAN P A ET AL., "A Post-Amadori Inhibitor Pyridoxamine Also Inhibits Chemical Modification of Proteins by Scavenging Carbonyl Intermediates of Carbohydrate and Lipid Degradation", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (20020201), vol. 277, no. 5, pages 3397 - 3403
by applicantJPS58169458
 JPS62142114
 JPS62249908
 JPS62249709
 JPS6319149
 JPS6456614
 JPS6483059
 JPH02156
 JPH02765
 JPH02753
 JPH0242053
 JPH0262885
 JPH02167264
 JPH03148220
 JPH03161441
 WO9111997
 JPH03204874
 JPH03240725
 JPH03261772
 JPH049375
 JPH04502611
 JPH04308586
 JPH059114
 JPH05105633
 JPH05505189
 JPH05201993
 JPH05255130
 JPH05310565
 JPH069380
 WO9404520
 JPH06135968
 JPH06192089
 JPH06206818
 JPH06256280
 JPH06287179
 JPH06287180
 JPH06298737
 JPH06298738
 JPH06305964
 JPH06305959
 JPH07500580
 JPH07500811
 JPH07503713
 JPH07133264
 JPH07196498
 JPH07206838
 JPH07247296
 JPH07323084
 JPH0859485
 JPH0871146
 JPH0885701
 JPH08131541
 JPH08157473
 JPH0940626
 JPH0940519
 JPH0959258
 JPH0959233
 WO9709981
 JPH09124471
 JPH09221427
 JPH09241165
 JPH09315960
 JPH1094598
 JPH10158244
 JPH10158265
 JPH10167965
 JPH10175954
 JPH10182460
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.