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Extract from the Register of European Patents

EP About this file: EP2242496

EP2242496 - METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.02.2018
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  03.03.2017
FormerGrant of patent is intended
Status updated on  01.11.2016
Most recent event   Tooltip26.06.2020Lapse of the patent in a contracting state
New state(s): CY, MK		published on 29.07.2020  [2020/31]
Applicant(s)For all designated states
Liu, Kui
Askims Svartmosseväg 36
436 39 Askim / SE
[2017/14]
Former [2010/43]For all designated states
Liu, Kui
Sjöfruvägen 99
907 51 Umeå / SE
Inventor(s)01 / see applicant
...
 [2010/43]
Representative(s)Zacco Sweden AB
P.O. Box 5581
Löjtnantsgatan 21
114 85 Stockholm / SE
[N/P]
Former [2017/14]Zacco Sweden AB
Valhallavägen 117
Box 5581
114 85 Stockholm / SE
Former [2010/43]Fagerlin, Heléne, et al
Albihns.Zacco Valhallavägen 117 Box 5581
114 85 Stockholm / SE
Application number, filing date09702221.419.01.2009
[2010/43]
WO2009SE50049
Priority number, dateUS2008002163917.01.2008         Original published format: US 21639
US2008002421029.01.2008         Original published format: US 24210
[2010/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009091332
Date:23.07.2009
Language:EN
[2009/30]
Type: A1 Application with search report 
No.:EP2242496
Date:27.10.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 23.07.2009 takes the place of the publication of the European patent application.
[2010/43]
Type: B1 Patent specification 
No.:EP2242496
Date:05.04.2017
Language:EN
[2017/14]
Search report(s)International search report - published on:SE23.07.2009
(Supplementary) European search report - dispatched on:EP08.04.2011
ClassificationIPC:A61K33/24, A61P15/08, A61P43/00, G01N33/573
[2010/43]
CPC:
A61B17/43 (US); A61B17/435 (US); A61P15/00 (EP);
A61P15/08 (EP); A61P43/00 (EP); C12N15/8776 (US);
C12N5/0609 (US); C12N5/0682 (US); C12Q1/42 (EP,US);
G01N33/502 (EP,US); C12N2501/73 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/14]
Former [2010/43]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERFAHREN ZUR IN-VITRO-REIFUNG VON OVARIALFOLLIKELN[2010/43]
English:METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES[2010/43]
French:PROCÉDÉS DE MATURATION IN VITRO DE FOLLICULES OVARIENS[2010/43]
Entry into regional phase16.08.2010National basic fee paid 
16.08.2010Search fee paid 
16.08.2010Designation fee(s) paid 
16.08.2010Examination fee paid 
Examination procedure17.11.2009Request for preliminary examination filed
International Preliminary Examining Authority: SE
16.08.2010Examination requested  [2010/43]
25.10.2011Amendment by applicant (claims and/or description)
01.02.2013Despatch of a communication from the examining division (Time limit: M04)
03.06.2013Reply to a communication from the examining division
12.01.2016Despatch of a communication from the examining division (Time limit: M06)
08.07.2016Reply to a communication from the examining division
02.11.2016Communication of intention to grant the patent
15.02.2017Fee for grant paid
15.02.2017Fee for publishing/printing paid
15.02.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.02.2013
Opposition(s)08.01.2018No opposition filed within time limit [2018/11]
Fees paidRenewal fee
26.04.2011Renewal fee patent year 03
20.01.2012Renewal fee patent year 04
15.01.2013Renewal fee patent year 05
23.01.2014Renewal fee patent year 06
19.01.2015Renewal fee patent year 07
26.01.2016Renewal fee patent year 08
30.01.2017Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.01.201103   M06   Fee paid on   26.04.2011
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.01.2009
AT05.04.2017
CY05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
MC05.04.2017
MK05.04.2017
NL05.04.2017
PL05.04.2017
PT05.04.2017
RO05.04.2017
SE05.04.2017
SI05.04.2017
SK05.04.2017
TR05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
[2020/31]
Former [2020/27]HU19.01.2009
AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
MC05.04.2017
NL05.04.2017
PL05.04.2017
PT05.04.2017
RO05.04.2017
SE05.04.2017
SI05.04.2017
SK05.04.2017
TR05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2020/15]AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
MC05.04.2017
NL05.04.2017
PL05.04.2017
RO05.04.2017
SE05.04.2017
SI05.04.2017
SK05.04.2017
TR05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2019/30]AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
MC05.04.2017
NL05.04.2017
PL05.04.2017
RO05.04.2017
SE05.04.2017
SI05.04.2017
SK05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2018/25]AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
NL05.04.2017
PL05.04.2017
RO05.04.2017
SE05.04.2017
SI05.04.2017
SK05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2018/11]AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
IT05.04.2017
LT05.04.2017
LV05.04.2017
NL05.04.2017
PL05.04.2017
RO05.04.2017
SE05.04.2017
SK05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2018/10]AT05.04.2017
CZ05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
LT05.04.2017
LV05.04.2017
NL05.04.2017
PL05.04.2017
RO05.04.2017
SE05.04.2017
SK05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2018/09]AT05.04.2017
DK05.04.2017
EE05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
LT05.04.2017
LV05.04.2017
NL05.04.2017
PL05.04.2017
SE05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2017/50]AT05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
LT05.04.2017
LV05.04.2017
NL05.04.2017
PL05.04.2017
SE05.04.2017
BG05.07.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2017/49]AT05.04.2017
ES05.04.2017
FI05.04.2017
HR05.04.2017
LT05.04.2017
NL05.04.2017
NO05.07.2017
GR06.07.2017
IS05.08.2017
Former [2017/48]NL05.04.2017
Documents cited:Search[X]  - CUMMINGS CATHY ET AL, "A peroxovanadium compound induces Xenopus oocyte maturation: Inhibition by a neutralizing anti-insulin receptor antibody", DEVELOPMENTAL BIOLOGY, (1996), vol. 175, no. 2, ISSN 0012-1606, pages 338 - 346, XP002630582 [X] 1-10 * abstract * * page 340, columns l-h, paragraph l - columns r-h, paragraph 2; figure 1 * * page 343, columns r-h, paragraph 2 *

DOI:   http://dx.doi.org/10.1006/dbio.1996.0119
International search[Y]WO2005019440  (NORTH SYDNEY AREA HEALTH SERV [AU], et al);
 [X]  - SCHMID, ANNETTE C. ET AL., "Bisperoxovanadium compounds are potent PTEN inhibitors", FEBS LETTERS, (2004), pages 35 - 38, XP008155698

DOI:   http://dx.doi.org/10.1016/j.febslet.2004.03.102
 [X]  - ROSIVATZ, E. ET AL., "A small-molecule inhibitor for phasphatase and tensin homologue deleted on chromosome 10 (PTEN)", ACS CHEMICAL BIOLOGY, (2006), vol. 1, no. 12, doi:doi:10.1021/CB60352F, pages 780 - 790, XP003025184

DOI:   http://dx.doi.org/10.1021/CB60352F
 [Y]  - HSU, S.-Y. ET AL., "Synergistic induction of ovulation and prostaglandin synthesis in goldfish (carassius auratus) follicles by sodium orthovanadate and hydrogen peroxide", BIOLOGY OF REPRODUCTION, (1991), vol. 45, doi:doi:10.1095/biolreprod45.6.912, pages 912 - 917, XP003025185

DOI:   http://dx.doi.org/10.1095/biolreprod45.6.912
 [Y]  - POSNER, B. I. ET AL., "Peroxovanadium compounds", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (1994), vol. 269, no. 6, pages 4596 - 4604, XP008155700
 [YP]  - FAN, H.-Y. ET AL., "Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells", MOLECULAR ENDOCRINOLOGY, (2008), vol. 22, no. 9, doi:doi:10.1210/ME.2008-0095, pages 2128 - 2140, XP003025186

DOI:   http://dx.doi.org/10.1210/ME.2008-0095
 [YP]  - REDDY, P. ET AL., "Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool", SCIENCE, (2008), vol. 319, doi:doi:10.1126/SCIENCE.1152257, pages 611 - 613, XP003025187

DOI:   http://dx.doi.org/10.1126/SCIENCE.1152257
 [A]  - GOETZ, F. W., "Involvement of Protein Kinase C in Agonist-Stimulated Goldfish Ovulation", BIOLOGY OF REPRODUCTION, (1993), vol. 48, doi:doi:10.1095/biolreprod48.4.846, pages 846 - 850, XP003025188

DOI:   http://dx.doi.org/10.1095/biolreprod48.4.846
 [A]  - CHANG, K. J. ET AL., "Differential effects of gonadotropin and orthovanadate on oocyte maturation, ovulation and prostaglandin synthesis by rana ovarian follicles in vitro", THE JOURNAL OF EXPERIMENTAL ZOOLOGY, (1997), vol. 277, pages 155 - 165, XP003025189
 [A]  - HSU, S.-Y. ET AL., "Oxoanions stimulate in vitro ovulation and signal transduction pathways in goldfish (Carrasius auratus) follicles", AMERICAN JOURNAL OF PHYSIOLOGY (ENDOCRINOL. METAB. 26), (1992), vol. 263, pages E943 - E949
 [A]  - HAINAUT, P. ET AL., "Insulin-like effects of vanadate on glucose uptake and on maturation in Xenopus laevis oocytes", CELL REGULATION, (1991), vol. 2, pages 317 - 327, XP003025190
 [A]  - MAILHES, J. B. ET AL., "Vanadate, an inhibitor of tyrosine phosphatases, induced premauture anaphase in oocytes and aneuploidy and polyploidy in mouse bone marrow cells", MUTATION RESEARCH, (2003), vol. 538, doi:doi:10.1016/S1383-5718(03)00108-6, pages 101 - 107, XP003025191

DOI:   http://dx.doi.org/10.1016/S1383-5718(03)00108-6
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.