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Extract from the Register of European Patents

EP About this file: EP2235218

EP2235218 - METHOD, PROCESS, AND KIT FOR DIAGNOSIS OR PROGNOSIS OF COLORECTAL CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.09.2015
Database last updated on 11.09.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
Assistance Publique Hôpitaux De Paris
3 Avenue Victoria
75001 Paris / FR
For all designated states
Université Paris-Est Créteil Val de Marne
61 avenue du Général de Gaulle
94010 Creteil Cedex / FR
[2012/24]
Former [2010/40]For all designated states
Assistance Publique Hôpitaux De Paris
3 Avenue Victoria
75001 Paris / FR
Inventor(s)01 / SOBHANI, Iradj
13 Avenue du Nord
94100 Saint Maur / FR
02 / MANSOUR, Hicham
25 rue du général Facq
92350 Le Plessis Robinson / FR
 [2014/27]
Former [2010/40]01 / SOBHANI, Iradj
13 Avenue du Nord
F-94100 Saint Maur / FR
02 / MANSOUR, Hicham
25 rue du général Facq
F92350 Le Plessis Robinson / FR
Representative(s)Wagret, Frédéric
Cabinet Wagret
6, Avenue Daniel Lesueur
75007 Paris / FR
[N/P]
Former [2014/47]Wagret, Frédéric
Cabinet Wagret
19, rue de Milan
75009 Paris / FR
Former [2010/40]Wagret, Frédéric
Cabinet Wagret 19, rue de Milan
75009 Paris / FR
Application number, filing date09706518.923.01.2009
[2010/40]
WO2009FR50101
Priority number, dateFR2008000054331.01.2008         Original published format: FR 0800543
[2010/40]
Filing languageFR
Procedural languageFR
PublicationType: A2 Application without search report
No.:WO2009095596
Date:06.08.2009
Language:FR
[2009/32]
Type: A2 Application without search report 
No.:EP2235218
Date:06.10.2010
Language:FR
The application published by WIPO in one of the EPO official languages on 06.08.2009 takes the place of the publication of the European patent application.
[2010/40]
Type: B1 Patent specification 
No.:EP2235218
Date:19.11.2014
Language:FR
[2014/47]
Search report(s)International search report - published on:EP26.11.2009
ClassificationIPC:C12Q1/68
[2010/40]
CPC:
C12Q1/6886 (EP,US); C12Q2600/154 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/40]
TitleGerman:METHODE, VERFAHREN UND KIT ZUR DIAGNOSE ODER PROGNOSE VON KOLOREKTALKARZINOM[2010/40]
English:METHOD, PROCESS, AND KIT FOR DIAGNOSIS OR PROGNOSIS OF COLORECTAL CANCER[2010/40]
French:METHODE, PROCEDE, ET KIT DE DIAGNOSTIC, PRONOSTIC DU CANCER COLORECTAL[2010/40]
Entry into regional phase25.08.2010National basic fee paid 
25.08.2010Designation fee(s) paid 
25.08.2010Examination fee paid 
Examination procedure25.08.2010Examination requested  [2010/40]
15.10.2010Amendment by applicant (claims and/or description)
27.01.2011Despatch of a communication from the examining division (Time limit: M06)
12.09.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
18.10.2011Reply to a communication from the examining division
22.06.2012Despatch of a communication from the examining division (Time limit: M06)
20.12.2012Reply to a communication from the examining division
12.06.2013Despatch of a communication from the examining division (Time limit: M04)
11.10.2013Reply to a communication from the examining division
11.06.2014Communication of intention to grant the patent
10.10.2014Receipt of the translation of the claim(s)
13.10.2014Fee for grant paid
13.10.2014Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  27.01.2011
Opposition(s)20.08.2015No opposition filed within time limit [2015/44]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
18.10.2011Request for further processing filed
18.10.2011Full payment received (date of receipt of payment)
Request granted
03.11.2011Decision despatched
Fees paidRenewal fee
28.01.2011Renewal fee patent year 03
12.01.2012Renewal fee patent year 04
31.01.2013Renewal fee patent year 05
29.01.2014Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.01.2009
AT19.11.2014
BG19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
MK19.11.2014
MT19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SI19.11.2014
SK19.11.2014
TR19.11.2014
IE23.01.2015
LU23.01.2015
BE31.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
GB19.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
[2018/30]
Former [2017/39]HU23.01.2009
AT19.11.2014
BG19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
MT19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SI19.11.2014
SK19.11.2014
TR19.11.2014
IE23.01.2015
LU23.01.2015
BE31.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
GB19.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2017/03]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
MT19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SI19.11.2014
SK19.11.2014
IE23.01.2015
LU23.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
GB19.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2016/12]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SI19.11.2014
SK19.11.2014
IE23.01.2015
LU23.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
GB19.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2016/07]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
IE23.01.2015
LU23.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
GB19.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2016/03]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
IT19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
LU23.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2015/51]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
LU23.01.2015
CH31.01.2015
LI31.01.2015
FR02.02.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2015/47]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
LU23.01.2015
CH31.01.2015
LI31.01.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
DE01.08.2015
Former [2015/43]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
MC19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
LU23.01.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/39]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
LU23.01.2015
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/37]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
SK19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/36]AT19.11.2014
CY19.11.2014
CZ19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
RO19.11.2014
SE19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/35]AT19.11.2014
CY19.11.2014
DK19.11.2014
EE19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
SE19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/26]AT19.11.2014
CY19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
SE19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/25]AT19.11.2014
ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
SE19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/24]ES19.11.2014
FI19.11.2014
HR19.11.2014
LT19.11.2014
LV19.11.2014
NL19.11.2014
PL19.11.2014
SE19.11.2014
NO19.02.2015
GR20.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/23]ES19.11.2014
FI19.11.2014
LT19.11.2014
NL19.11.2014
NO19.02.2015
IS19.03.2015
PT19.03.2015
Former [2015/22]LT19.11.2014
NO19.02.2015
PT19.03.2015
Former [2015/21]LT19.11.2014
NO19.02.2015
Former [2015/20]LT19.11.2014
Cited inInternational search[A]US2005288226  (YOU LIANG [US], et al) [A] 1-10* page 2, [10] - [19] ; exemples *;
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 [X]  - "Human soft tissue sarcoma-upregulated DNA - SEQ ID 4235.", Geneseq, (20040826), Database accession no. ADQ21415, URL: EBI, XP002485843 [X] 6-8,10 * Sequence *
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DOI:   http://dx.doi.org/10.1093/carcin/bgl246
 [Y]  - URAKAMI SHINJI ET AL, "Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 1 DEC 2006, (20061201), vol. 12, no. 23, ISSN 1078-0432, pages 6989 - 6997, XP002547094 [Y] 1-5,9 * pages 6990-6991, "Materials and methods"; page 6992, figure 1; page 6993, colonne gauche; page 6997 *

DOI:   http://dx.doi.org/10.1158/1078-0432.ccr-06-1194
 [Y]  - URAKAMI S ET AL, "COMBINATION ANALYSIS OF HYPERMETHYLATED WNT-ANTAGONIST FAMILY GENES AS A NOVEL EPIGENETIC BIOMARKER PANEL FOR BLADDER CANCER DETECTION", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20060401), vol. 12, no. 7, ISSN 1078-0432, pages 2109 - 2116, XP003015934 [Y] 1-5,9 * page 2111, tableau 1; pages 2113-2116, "Discussion" *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-05-2468
 [Y]  - LENHARD ET AL, "Analysis of promoter methylation in stool: A novel method for the detection of colorectal cancer", CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, AMERICAN GASTROENTEROLOGICAL ASSOCIATION, US, (20050201), vol. 3, no. 2, ISSN 1542-3565, pages 142 - 149, XP005120680 [Y] 1-5,9 * pages 143 - 146, "Materials and methods" *

DOI:   http://dx.doi.org/10.1016/S1542-3565(04)00624-X
 [A]  - EBERT ET AL, "Aristaless-like Homeobox-4 Gene Methylation Is a Potential Marker for Colorectal Adenocarcinomas", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, (20061111), vol. 131, no. 5, ISSN 0016-5085, pages 1418 - 1430, XP005725528 [A] 1-4 * page 1418, dernier paragraphe ; page 1419, colonne droite *

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 [X]  - KOHONEN-CORISH M R J ET AL, "Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer", ONCOGENE, BASINGSTOKE, HANTS, GB, vol. 26, no. 30, ISSN 0950-9232, (20070601), pages 4435 - 4441, (20070129), XP002477017 [X] 1-4 * page 4440, colonne gauche ; pages 4436-4437 *

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 [A]  - ZOU HONGZHI ET AL, "Highly methylated genes in colorectal neoplasia: implications for screening.", CANCER EPIDEMIOLOGY, BIOMARKERS & PREVENTION : A PUBLICATION OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, COSPONSORED BY THE AMERICAN SOCIETY OF PREVENTIVE ONCOLOGY DEC 2007, (200712), vol. 16, no. 12, ISSN 1055-9965, pages 2686 - 2696, XP002485840 [A] 1-4 * page 2687, colonne gauche ; page 2688, tableau 2 *

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DOI:   http://dx.doi.org/10.1038/sj.onc.1208910
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