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Extract from the Register of European Patents

EP About this file: EP2249842

EP2249842 - USE OF 25-HYDROXY-VITAMIN D3 AND VITAMIN D TO AFFECT HUMAN MUSCLE PHYSIOLOGY [Right-click to bookmark this link]
Former [2010/46]USE OF 25-HYDROXY-VITAMIN D3 TO AFFECT HUMAN MUSCLE PHYSIOLOGY
[2016/10]
StatusThe patent has been granted
Status updated on  24.06.2016
Database last updated on 24.08.2024
Most recent event   Tooltip04.07.2024Change: Despatch of interlocutory decision 
Applicant(s)For all designated states
DSM IP Assets B.V.
Het Overloon 1
6411 TE Heerlen / NL
[2010/46]
Inventor(s)01 / BUCK, Neil, Robert
11b
rue du Ruisseau
F-68220 Leymen / FR
02 / CLAERHOUT, Wouter
Bollwerkstrasse 12
CH-4102 Binningen / CH
03 / LEUENBERGER, Bruno, H.
Magdenerstrasse 24
CH-4123 Rheinfelden / CH
04 / STOECKLIN, Elisabeth
Sonnenweg 1
CH-4144 Arlesheim / CH
05 / URBAN, Kai
Näfelsstrasse 21
79713 Bad Säckingen / DE
06 / WOLFRAM, Swen
Am Buchenhain 24
79761 Waldshut-Tiengen / DE
 [2016/30]
Former [2010/46]01 / BUCK, Neil, Robert
11b rue du Ruisseau
F-68220 Leymen / FR
02 / CLAERHOUT, Wouter
Bollwerkstrasse 12
CH-4102 Binningen / CH
03 / LEUENBERGER, Bruno, H.
Magdenerstrasse 24
CH-4123 Rheinfelden / CH
04 / STOECKLIN, Elisabeth
Sonnenweg 1
CH-4144 Arlesheim / CH
05 / URBAN, Kai
Näfelsstrasse 21
79713 Bad Säckingen / DE
06 / WOLFRAM, Swen
Am Buchenhain 24
79761 Waldshut-Tiengen / DE
Representative(s)Kraus & Lederer PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[N/P]
Former [2016/30]Rabanus, Birgit
DSM Nutritional Products AG
Patent Department
Wurmisweg 576
4303 Kaiseraugst / CH
Former [2014/13]Schwander, Kuno, et al
DSM Nutritional Products Ltd.
Patent Department
Wurmisweg 576
4303 Kaiseraugst / CH
Former [2013/03]Schiener, Jens, et al
Lederer & Keller
Patentanwälte
Unsöldstrasse 2
80538 München / DE
Former [2012/29]Schwander, Kuno, et al
DSM Nutritional Products Ltd
Patent Department
Wurmisweg 576
4303 Kaiseraugst / CH
Former [2010/46]Schwander, Kuno
DSM Nutritional Products Ltd., Wurmisweg 576
4303 Kaiseraugst / CH
Application number, filing date09710537.312.02.2009
[2010/46]
WO2009EP51641
Priority number, dateUS20080028510P13.02.2008         Original published format: US 28510 P
US20080031671P26.02.2008         Original published format: US 31671 P
US20080036924P14.03.2008         Original published format: US 36924 P
US20080036928P15.03.2008         Original published format: US 36928 P
US20080129139P06.06.2008         Original published format: US 129139 P
[2010/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009101137
Date:20.08.2009
Language:EN
[2009/34]
Type: A1 Application with search report 
No.:EP2249842
Date:17.11.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 20.08.2009 takes the place of the publication of the European patent application.
[2010/46]
Type: B1 Patent specification 
No.:EP2249842
Date:27.07.2016
Language:EN
[2016/30]
Search report(s)International search report - published on:EP20.08.2009
ClassificationIPC:A61K31/593, A61K31/59, A23L33/155, A61P21/00, A61P43/00, A61P21/06
[2024/29]
CPC:
A61K31/593 (EP,CN,KR,US); A23L33/155 (EP,CN,US); A61K31/59 (EP,US);
A61P21/00 (EP); A61P21/06 (EP); A61P43/00 (EP);
A23V2002/00 (EP,CN,US); Y02A50/30 (EP,US) (-)
C-Set:
A61K31/593, A61K2300/00 (US,EP);
A61K31/59, A61K2300/00 (US,EP);
A23V2002/00, A23V2200/316, A23V2250/7106 (EP,US);
A23V2002/00, A23V2250/7104, A23V2250/7106, A23V2200/30 (CN)
Former IPC [2016/10]A61K31/593, A61K31/59, A61P21/00
Former IPC [2010/46]A61K31/593, A23L1/303, A61P21/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/30]
Former [2010/46]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERWENDUNG VON 25-HYDROXY-VITAMIN D3 UND VITAMIN D ZUR EINWIRKUNG AUF DIE MENSCHLICHE MUSKELPHYSIOLOGIE[2016/10]
English:USE OF 25-HYDROXY-VITAMIN D3 AND VITAMIN D TO AFFECT HUMAN MUSCLE PHYSIOLOGY[2016/10]
French:UTILISATION DE 25-HYDROXY-VITAMINE D3 ET VITAMINE D POUR AGIR SUR LA PHYSIOLOGIE MUSCULAIRE[2016/10]
Former [2010/46]VERWENDUNG VON 25-HYDROXY-VITAMIN D3 ZUR EINWIRKUNG AUF DIE MENSCHLICHE MUSKELPHYSIOLOGIE
Former [2010/46]USE OF 25-HYDROXY-VITAMIN D3 TO AFFECT HUMAN MUSCLE PHYSIOLOGY
Former [2010/46]UTILISATION DE 25-HYDROXY-VITAMINE D3 POUR AGIR SUR LA PHYSIOLOGIE MUSCULAIRE
Entry into regional phase16.07.2010National basic fee paid 
16.07.2010Designation fee(s) paid 
16.07.2010Examination fee paid 
Examination procedure16.07.2010Examination requested  [2010/46]
29.10.2010Amendment by applicant (claims and/or description)
11.04.2014Despatch of a communication from the examining division (Time limit: M04)
23.07.2014Reply to a communication from the examining division
13.03.2015Despatch of a communication from the examining division (Time limit: M04)
18.03.2015Reply to a communication from the examining division
15.03.2016Communication of intention to grant the patent
15.06.2016Fee for grant paid
15.06.2016Fee for publishing/printing paid
15.06.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.04.2014
Opposition(s)Opponent(s)01  26.04.2017    ADMISSIBLE
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Nederlandsch Octrooibureau, et al, et al
P.O. Box 29720
2502 LS The Hague / NL
 [2017/22]
07.06.2017Invitation to proprietor to file observations on the notice of opposition
04.10.2017Reply of patent proprietor to notice(s) of opposition
14.09.2018Date of oral proceedings
20.12.2018Despatch of minutes of oral proceedings
12.09.2023Despatch of a communication from the opposition division (Time limit: M02)
23.10.2023Reply to a communication from the opposition division
30.01.2024Despatch of a communication from the opposition division (Time limit: M02)
08.07.2024Despatch of interlocutory decision in opposition
Appeal following opposition19.02.2019Appeal received No.  T0578/19
30.04.2019Statement of grounds filed
03.05.2023Result of appeal procedure: maintenance in amended form
23.06.2023Despatch of the decision of the Board of Appeal
20.02.2019Appeal received No.  T0578/19
29.04.2019Statement of grounds filed
03.05.2023Result of appeal procedure: maintenance in amended form
23.06.2023Despatch of the decision of the Board of Appeal
03.05.2023Date of oral proceedings
Fees paidRenewal fee
23.02.2011Renewal fee patent year 03
15.02.2012Renewal fee patent year 04
12.02.2013Renewal fee patent year 05
12.02.2014Renewal fee patent year 06
11.02.2015Renewal fee patent year 07
10.02.2016Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.02.2009
AT27.07.2016
BE27.07.2016
CY27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
MK27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
IE12.02.2017
LU12.02.2017
MT12.02.2017
CH28.02.2017
LI28.02.2017
[2019/51]
Former [2019/46]HU12.02.2009
AT27.07.2016
BE27.07.2016
CY27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
IE12.02.2017
LU12.02.2017
MT12.02.2017
CH28.02.2017
LI28.02.2017
Former [2019/31]HU12.02.2009
AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
IE12.02.2017
LU12.02.2017
MT12.02.2017
CH28.02.2017
LI28.02.2017
Former [2018/43]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
IE12.02.2017
LU12.02.2017
MT12.02.2017
CH28.02.2017
LI28.02.2017
Former [2018/13]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
IE12.02.2017
LU12.02.2017
CH28.02.2017
LI28.02.2017
Former [2018/04]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
LU12.02.2017
CH28.02.2017
LI28.02.2017
Former [2017/51]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
CH28.02.2017
LI28.02.2017
Former [2017/45]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
MC27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
Former [2017/37]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SI27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
Former [2017/31]AT27.07.2016
BE27.07.2016
CZ27.07.2016
DK27.07.2016
EE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
NL27.07.2016
RO27.07.2016
SE27.07.2016
SK27.07.2016
BG27.10.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
Former [2017/13]AT27.07.2016
BE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
LV27.07.2016
NL27.07.2016
SE27.07.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
Former [2017/11]AT27.07.2016
BE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
NL27.07.2016
SE27.07.2016
NO27.10.2016
GR28.10.2016
IS27.11.2016
PT28.11.2016
Former [2017/10]BE27.07.2016
FI27.07.2016
HR27.07.2016
LT27.07.2016
NL27.07.2016
SE27.07.2016
NO27.10.2016
IS27.11.2016
Former [2017/09]FI27.07.2016
LT27.07.2016
NL27.07.2016
NO27.10.2016
Former [2017/07]LT27.07.2016
Cited inInternational search[DX]US2003170324  (TRITSCH JEAN-CLAUDE [US], et al) [DX] 4-6 * claims 1,26,34,48,49 * * paragraphs [0061] - [0065] *;
 [X]US2007082089  (KRAMMER STEPHANIE [DE], et al) [X] 4-6 * claims 1,2,6,7 *;
 [DX]WO2007059960  (DSM IP ASSETS BV [NL], et al) [DX] 4-6 * claim 1 * * page 3, lines 10,11 * * page 3, line 27 - page 4, line 5 *;
 [X]  - WHYTE M P ET AL, "Rickets and osteomalacia", MEDICINE,, vol. 33, no. 12, ISSN 1357-3039, (20051201), pages 70 - 74, (20051201), XP025344242 [X] 4-6 * page 72 *

DOI:   http://dx.doi.org/10.1383/medc.2005.33.12.70
 [X]  - GARAY LILLO J ET AL, "Geminis Project: Prospective, multicentric and random study for evaluating the effect of tricalcium phosphate versus tricalcium phosphate plus 25 (OH) vitamin D on the risk of fractures in elderly women", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1997), Database accession no. PREV199799742655, XP002525526 [X] 1-6 * abstract *
    [ ] - GERIATRIKA (MADRID), (1997), vol. 13, no. 6, ISSN 0212-9744, pages 24 - 28
 [X]  - EASTWOOD J B ET AL, "THE EFFECT OF 25 HYDROXY VITAMIN D3 IN THE OSTEOMALACIA OF CHRONIC RENAL FAILURE", CLINICAL SCIENCE AND MOLECULAR MEDICINE, BLACKWELL SCIENTIFIC PUBLICATIONS, OXFORD, GB, (19770101), vol. 52, no. 5, ISSN 0301-0538, pages 499 - 508, XP009085521 [X] 1-6 * abstract * * page 502, column 1, paragraph 2 * * page 503, column 1, paragraph 2 * * page 507, column 1, paragraph 1 *
 [X]  - BARBIZET J ET AL, "[Myopathy, osteomalacia, and congenital hypoalbuminemia (author's transl)]", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (1981), Database accession no. NLM7256069, XP002526397 [X] 1-6 * abstract *
    [ ] - REVUE NEUROLOGIQUE 1981, (1981), vol. 137, no. 3, ISSN 0035-3787, pages 195 - 202
 [X]  - RIMANIOL J M ET AL, "Muscle weakness in intensive care patients: initial manifestation of vitamin D deficiency.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (199411), Database accession no. NLM7706575, XP002526398 [X] 1-6 * abstract *
    [ ] - INTENSIVE CARE MEDICINE NOV 1994, (199411), vol. 20, no. 8, ISSN 0342-4642, pages 591 - 592
 [Y]  - GRANT ET AL, "Epidemiology of disease risks in relation to vitamin D insufficiency", PROGRESS IN BIOPHYSICS AND MOLECULAR BIOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 92, no. 1, ISSN 0079-6107, (20060901), pages 65 - 79, (20060901), XP025078432 [Y] 1-6 * abstract; page 66, paragraph 2 * * page 67, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/j.pbiomolbio.2006.02.013
 [Y]  - SATO YOSHIHIRO ET AL, "Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial.", CEREBROVASCULAR DISEASES (BASEL, SWITZERLAND) 2005, (2005), vol. 20, no. 3, ISSN 1015-9770, pages 187 - 192, XP009115855 [Y] 1-6 * Abstract *

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 [Y]  - BISCHOFF-FERRARI ET AL, "Vitamin D and muscle function", INTERNATIONAL CONGRESS SERIES, EXCERPTA MEDICA, AMSTERDAM, (20070301), vol. 1297, ISSN 0531-5131, pages 143 - 147, XP022003749 [Y] 1-6 * whole document *

DOI:   http://dx.doi.org/10.1016/j.ics.2006.08.007
 [Y]  - PFEIFER M ET AL, "Vitamin D and muscle function.", OSTEOPOROSIS INTERNATIONAL : A JOURNAL ESTABLISHED AS RESULT OF COOPERATION BETWEEN THE EUROPEAN FOUNDATION FOR OSTEOPOROSIS AND THE NATIONAL OSTEOPOROSIS FOUNDATION OF THE USA MAR 2002, (200203), vol. 13, no. 3, ISSN 0937-941X, pages 187 - 194, XP002526396 [Y] 1-6 * whole document *

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 [Y]  - BARGER-LUX M J ET AL, "Vitamin D and its major metabolites: Serum levels after graded oral dosing in healthy men", OSTEOPOROSIS INTERNATIONAL, XX, XX, (19980101), vol. 8, no. 3, pages 222 - 230, XP002438418 [Y] 1-6 * abstract * * table 2 *
OppositionWO2007092755
 WO2009047644
 WO2009101137
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.