blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2249774

EP2249774 - MEANS AND METHODS FOR CONTROLLING COMMENSALES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.03.2015
Database last updated on 20.12.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK
published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
B.R.A.I.N.
BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG Darmstädter Strasse 34-36
64673 Zwingenberg / DE
[2010/46]
Inventor(s)01 / DECHERT, Ute
Moosbergstrasse 10
64285 Darmstadt / DE
02 / ECK, Jürgen
Jacobsweg 48
64425 Bensheim / DE
03 / KROHN, Michael
Alexanderstrasse 8
64653 Lorsch / DE
 [2010/46]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2014/20]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Former [2010/46]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date09712381.418.02.2009
[2010/46]
WO2009EP01135
Priority number, dateEP2008000296318.02.2008         Original published format: EP 08002963
[2010/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009103500
Date:27.08.2009
Language:EN
[2009/35]
Type: A1 Application with search report 
No.:EP2249774
Date:17.11.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 27.08.2009 takes the place of the publication of the European patent application.
[2010/46]
Type: B1 Patent specification 
No.:EP2249774
Date:14.05.2014
Language:EN
[2014/20]
Search report(s)International search report - published on:EP27.08.2009
ClassificationIPC:A61K8/35, A61Q19/10, A61P17/10, A61Q19/00
[2010/46]
CPC:
A61K8/35 (EP,US); A61L27/54 (EP,US); A61L29/16 (EP,US);
A61L31/16 (EP,US); A61P17/10 (EP); A61Q17/005 (EP,US);
A61L2300/404 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/46]
TitleGerman:MITTEL UND VERFAHREN ZUR KONTROLLE VON KOMMENSALEN[2010/46]
English:MEANS AND METHODS FOR CONTROLLING COMMENSALES[2010/46]
French:MOYENS ET PROCÉDÉS DE LUTTE CONTRE LES COMMENSAUX[2010/46]
Entry into regional phase09.09.2010National basic fee paid 
09.09.2010Designation fee(s) paid 
09.09.2010Examination fee paid 
Examination procedure09.09.2010Examination requested  [2010/46]
14.10.2010Amendment by applicant (claims and/or description)
15.11.2011Despatch of a communication from the examining division (Time limit: M04)
26.03.2012Reply to a communication from the examining division
09.10.2013Cancellation of oral proceeding that was planned for 21.10.2013
21.10.2013Date of oral proceedings (cancelled)
20.11.2013Communication of intention to grant the patent
28.03.2014Fee for grant paid
28.03.2014Fee for publishing/printing paid
28.03.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.11.2011
Opposition(s)17.02.2015No opposition filed within time limit [2015/17]
Fees paidRenewal fee
21.02.2011Renewal fee patent year 03
23.02.2012Renewal fee patent year 04
25.02.2013Renewal fee patent year 05
21.02.2014Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.02.2009
AT14.05.2014
BE14.05.2014
BG14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
MC14.05.2014
MK14.05.2014
MT14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SI14.05.2014
SK14.05.2014
TR14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
[2018/30]
Former [2017/39]HU18.02.2009
AT14.05.2014
BE14.05.2014
BG14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
MC14.05.2014
MT14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SI14.05.2014
SK14.05.2014
TR14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2017/03]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
MC14.05.2014
MT14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SI14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/46]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
MC14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SI14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/36]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SI14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/22]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
IT14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/11]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
RO14.05.2014
SE14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/10]AT14.05.2014
BE14.05.2014
CY14.05.2014
CZ14.05.2014
DK14.05.2014
EE14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
SE14.05.2014
SK14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/08]AT14.05.2014
BE14.05.2014
CY14.05.2014
DK14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
SE14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2015/02]AT14.05.2014
CY14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
SE14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
PT15.09.2014
Former [2014/51]AT14.05.2014
CY14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
SE14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
Former [2014/50]CY14.05.2014
ES14.05.2014
FI14.05.2014
HR14.05.2014
LT14.05.2014
LV14.05.2014
PL14.05.2014
SE14.05.2014
NO14.08.2014
GR15.08.2014
IS14.09.2014
Former [2014/49]CY14.05.2014
FI14.05.2014
LT14.05.2014
NO14.08.2014
IS14.09.2014
Former [2014/48]CY14.05.2014
LT14.05.2014
Former [2014/47]CY14.05.2014
Cited inInternational search[X]KR20070100046  (KOREA RES INST OF BIOSCIENCE [KR], et al) [X] 1,4-8 * the whole document *;
 [DX]WO2005055995  (KOREA RES INST OF BIOSCIENCE [KR], et al) [DX] 1,4-8 * the whole document *;
 [DX]  - JOAN MALMSTROEM ET AL, "Bioactive Metabolites from a Marine-Derived Strain of the Fungus Emericella variecolor", JOURNAL OF NATURAL PRODUCTS, XX, XX, (20020101), vol. 65, ISSN 0163-3864, pages 364 - 367, XP002308197 [DX] 1-3,6-8 * the whole document *

DOI:   http://dx.doi.org/10.1021/np0103214
Examination   - CH.C.ZOUBOULIS, "Moderne Aknetherapie", AKTUELLE DERMATOLOGIE, (2003), vol. 29, no. 1-2, ISSN 0340-2541, pages 49 - 57
by applicantWO2005055995
 WO2006053613
    - BURKHART, C.N.; BURKHART, C.G., "Microbiology's principle of biofilms as a major factor in the pathogenesis of acne vulgaris", INT. J. DERMATOL., (2003), vol. 42, pages 925 - 927
    - CLUTTERBUCK, P.W.; RAISTRICK, H.; REUTER, F., "Studies in the biochemistry of micro- organisms: The molecular constitution of terrein, a metabolic product of Aspergillus terreus Thom", BIOCHEM. J., (1937), vol. 62, pages 987 - 1002
    - DEL ROSSO, J.Q., "Combination topical therapy in the treatment of acne", CUTIS, CUTANEOUS MEDICINE FOR THE PRACTITIONER, (2006), vol. 78, pages 5 - 12
    - DONLAN, R. M., "Biofilm formation: a clinically relevant microbiological process", CLIN INFECT DIS., (2001), vol. 33, pages 1387 - 1392
    - EADY, E.A.; GLOOR, M.; LEYDEN, J.J., "Propionibacterium acnes resistance: a worldwide problem", DERMATOLOGY, (2003), vol. 206, pages 54 - 56
    - HE, J.; LION, U.; SATTLER, I.; GOLLMICK, F.A.; GRABLEY, S.; CAI, J.; MEINERS, M.; SCHÜNKE, H.; SCHAUMANN, K.; DECHERT, U., "Diastereomeric Quinolinone Alkaloids from the Marine-Derived Fungus Penicillium janczewskii", J. NAT. PROD., (2005), vol. 68, pages 1397 - 1399
    - LEE, T.-W.; KIM, J.-C.; HWANG, S.-J, "Hydrogel patches containing triclosan for acne treatment", EUR. J. PHARM. BIOPHARM., (2003), vol. 56, pages 407 - 412
    - LEE, S.; KIM, W.-G.; KIM, E.; RYOO, I.-J.; LEE, H.K.; KIM, J.N.; JUNG, S.-H.; YOO, I.-D., "Synthesis and melanin biosynthesis inhibitory activity of (+/-)-terrein produced by Penicillium sp. 20135", BIOORG. MED. CHEM.LETT., (2005), vol. 15, pages 471 - 473
    - MALMSTROM, J.; CHRISTOPHERSEN, C.; BARRERO, A.F.; OLTRA, J.E.; JUSTICIA, J.; ROSALES, A., "Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor", J. NAT. PROD., (2002), vol. 65, pages 364 - 367
    - MACK, D.; DAVIES, A.P.; HARRIS, L.G.; ROHDE, H.; HORSTKOTTE, M.A.; KNOBLOCH, J.K.-M., "Microbial interactions in Staphylococcus epidermidis biofilms", ANAL. BIOANAL. CHEM., (2007), vol. 387, pages 399 - 408
    - NADELL, C.D.; XAVIER, J.B.; LEVIN, S.A.; FOSTER, K.R., "The evolution of quorum sensing in bacterial biofilms", PIOS BIOL., (2008), vol. 6, page E14
    - NENOFF, P.; HAUSTEIN, U.-F.; HITTEL, N., "Activity of nadifloxacin (OPC-7251) and seven other antimicrobial agents against aerobic and anaerobic Gram-positive bacteria isolated from bacterial skin infections", CHEMOTHERAPY, (2004), vol. 50, pages 196 - 201
    - O'TOOLE, G.A.; KOLTER, R., "Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis", MOL. MICROBIOL., (1998), vol. 28, pages 449 - 461
    - PARK, S.-H.; KIM, D.-S.; KIM, W.-G.; RYOO, I.-J.; LEE, D.-H.; HUH, C.-H.; YOUN, S.-W.; YOO, I.-D.; PARK, K.-C., "Terrein: a new melanogenesis inhibitor and its mechanism, Cell", MOL, LIFE SCI., (2004), vol. 61, pages 2878 - 2885
    - RAISTRICK, H.; SMITH, G., "Studies in the biochemistry of micro-organisms: The metabolic products of Aspergillus terreus Thom. A new mould metabolic product- terrein", BIOCHEM. J., (1935), vol. 29, pages 606 - 611
    - ROSS, J.I.; SNELLING, A.M.; EADY, E.A.; COVE, J.H.; CUNLIFFE, W.J.; LEYDEN, J.J.; COLLIGNON, P.; DRENO, B.; REYNAUD, A.; FLUHR, J., "Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia", BR. J. DERMATOL, (2001), vol. 144, pages 339 - 346
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.