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Extract from the Register of European Patents

EP About this file: EP2269071

EP2269071 - METHODS AND AGENTS FOR THE DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOMA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.08.2015
Database last updated on 25.09.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
China Synthetic Rubber Corporation
8th Floor, No. 113, Section 2
Zhongshan North Rd.
Taipei 104
Taiwan / TW
[2014/38]
Former [2011/01]For all designated states
China Synthetic Rubber Corporation
7th Floor, n 113, Section 2, Zhongshan Norh Rd.
Taipei 104 / TW
Inventor(s)01 / KAO, Kuo-Jang
119 NW 101st Court
Gainesville, FL 32607 / US
02 / HUANG, Andrew T.
4841 Moriah Hill Road
Durham, NC 27707 / US
 [2011/01]
Representative(s)Potter Clarkson
Chapel Quarter
Mount Street
Nottingham NG1 6HQ / GB
[N/P]
Former [2014/40]Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham, NG1 5GG / GB
Former [2013/37]Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham
NG1 5GG / GB
Former [2011/01]Simpson, Mark Geoffrey, et al
Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham
NG1 5DD / GB
Application number, filing date09723224.318.03.2009
[2011/01]
WO2009US01689
Priority number, dateUS20080069910P19.03.2008         Original published format: US 69910 P
[2011/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009117096
Date:24.09.2009
Language:EN
[2009/39]
Type: A1 Application with search report 
No.:EP2269071
Date:05.01.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 24.09.2009 takes the place of the publication of the European patent application.
[2011/01]
Type: B1 Patent specification 
No.:EP2269071
Date:01.10.2014
Language:EN
[2014/40]
Search report(s)International search report - published on:EP24.09.2009
ClassificationIPC:G01N33/574, C07K16/28, C07K16/30, C12Q1/68, C07K14/705
[2011/01]
CPC:
C07K16/28 (EP,KR,US); A61K39/395 (KR); A61K39/39558 (US);
A61K45/06 (US); A61K51/1018 (US); A61K51/1027 (EP,US);
A61K51/1057 (EP,US); A61P1/16 (EP); A61P35/00 (EP);
A61P43/00 (EP); C07K14/705 (KR); C07K16/303 (EP,US);
C12Q1/68 (KR); G01N33/574 (KR); G01N33/57438 (EP,US);
G01N33/577 (US); C07K2317/56 (EP,US); C07K2317/565 (EP,US);
C07K2317/92 (EP,US); C07K2319/21 (EP,US); C12Q1/6886 (EP,US);
G01N2333/47 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/01]
TitleGerman:VERFAHREN UND WIRKSTOFFE ZUR DIAGNOSE UND BEHANDLUNG EINES LEBERZELLENKARZINOMS[2011/01]
English:METHODS AND AGENTS FOR THE DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOMA[2011/01]
French:PROCÉDÉS ET AGENTS POUR LE DIAGNOSTIC ET LE TRAITEMENT D UN CARCINOME HÉPATOCELLULAIRE[2011/01]
Entry into regional phase15.10.2010National basic fee paid 
15.10.2010Designation fee(s) paid 
15.10.2010Examination fee paid 
Examination procedure15.10.2010Examination requested  [2011/01]
07.12.2010Amendment by applicant (claims and/or description)
02.05.2011Despatch of a communication from the examining division (Time limit: M04)
30.08.2011Reply to a communication from the examining division
08.12.2011Despatch of a communication from the examining division (Time limit: M06)
25.05.2012Reply to a communication from the examining division
07.01.2013Despatch of a communication from the examining division (Time limit: M06)
12.07.2013Reply to a communication from the examining division
11.04.2014Communication of intention to grant the patent
20.08.2014Fee for grant paid
20.08.2014Fee for publishing/printing paid
20.08.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  02.05.2011
Opposition(s)02.07.2015No opposition filed within time limit [2015/37]
Fees paidRenewal fee
29.03.2011Renewal fee patent year 03
26.03.2012Renewal fee patent year 04
27.03.2013Renewal fee patent year 05
27.03.2014Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.03.2009
BG01.10.2014
CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
MK01.10.2014
MT01.10.2014
PL01.10.2014
RO01.10.2014
SI01.10.2014
SK01.10.2014
TR01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
IE18.03.2015
LU18.03.2015
[2018/30]
Former [2017/39]HU18.03.2009
BG01.10.2014
CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
MT01.10.2014
PL01.10.2014
RO01.10.2014
SI01.10.2014
SK01.10.2014
TR01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
IE18.03.2015
LU18.03.2015
Former [2017/03]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
MT01.10.2014
PL01.10.2014
RO01.10.2014
SI01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
IE18.03.2015
LU18.03.2015
Former [2016/12]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
PL01.10.2014
RO01.10.2014
SI01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
IE18.03.2015
LU18.03.2015
Former [2016/07]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
PL01.10.2014
RO01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
IE18.03.2015
LU18.03.2015
Former [2015/47]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
PL01.10.2014
RO01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
LU18.03.2015
Former [2015/46]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
MC01.10.2014
PL01.10.2014
RO01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/37]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
PL01.10.2014
RO01.10.2014
SK01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/36]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
PL01.10.2014
RO01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/35]CY01.10.2014
CZ01.10.2014
EE01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
PL01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/26]CY01.10.2014
CZ01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
PL01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/24]CZ01.10.2014
FI01.10.2014
HR01.10.2014
LT01.10.2014
LV01.10.2014
PL01.10.2014
GR02.01.2015
IS01.02.2015
PT02.02.2015
Former [2015/23]CZ01.10.2014
FI01.10.2014
LT01.10.2014
IS01.02.2015
PT02.02.2015
Former [2015/22]LT01.10.2014
PT02.02.2015
Former [2015/20]LT01.10.2014
Cited inInternational search[X]WO03023008  (CURAGEN CORP [US], et al) [X] 18-20,23-33,60,61 * page 229 - page 230 * * page 444 - page 460 *;
 [X]WO03024392  (GENENTECH INC [US]) [X] 18-20,23-33,60,61 * page 132, lines 1-11 * * figure 54 *;
 [PX]WO2008091781  (MAYO FOUNDATION [US], et al) [PX] 1-3,5,9-11,17-34,37,54-56,60-66,71-74* the whole document *;
 [X]  - STRICKLAND LAURA A ET AL, "Plasmalemmal vesicle-associated protein (PLVAP) is expressed by tumour endothelium and is upregulated by vascular endothelial growth factor-A (VEGF).", THE JOURNAL OF PATHOLOGY AUG 2005, (200508), vol. 206, no. 4, ISSN 0022-3417, pages 466 - 475, XP002535808 [X] 38-53,64,65,73-80 * page 476 *

DOI:   http://dx.doi.org/10.1002/PATH.1805
Examination   - WOLFF ANTONIO C ET AL, "AMERICAN SOCIETY OF CLINICAL ONCOLOGY/COLLEGE OF AMERICAN PATHOLOGISTS GUIDELINE RECOMMENDATIONS FOR HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 TESTING IN BREAST CANCER", ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, COLLEGE OF AMERICAN PATHOLOGISTS, US, (20070101), vol. 131, no. 1, ISSN 0003-9985, pages 18 - 43, XP008077476
    - HO S ET AL, "INTERNAL RADIATION THERAPY FOR PATIENTS WITH PRIMARY OR METASTATIC HEPATIC CANCER: A REVIEW", CANCER, AMERICAN CANCER SOCIETY, PHILADELPHIA, PA, US, (19981101), vol. 83, no. 9, doi:10.1002/(SICI)1097-0142(19981101)83:9<,1894::AID-CNCR4>,3.0.CO,2, ISSN 0008-543X, pages 1894 - 1907, XP009067538

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0142(19981101)83:9<1894::AID-CNCR4>3.0.CO;2-O
    - YANG JIAHUI ET AL, "Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies.", PLOS ONE 2011 LNKD- PUBMED:21698301, (2011), vol. 6, no. 6, ISSN 1932-6203, page e21018
    - OERNTOFT T F ET AL, "GENOME-WIDE STUDY OF GENE COPY NUMBERS, TRANSCRIPTS, AND PROTEIN LEVELS IN PAIRS OF NON-INVASIVE AND INVASIVE HUMAN TRANSITIONAL CELL CARCINOMAS", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, (20020101), vol. 1, no. 1, doi:10.1074/MCP.M100019-MCP200, ISSN 1535-9476, pages 37 - 45, XP008015037

DOI:   http://dx.doi.org/10.1074/mcp.M100019-MCP200
by applicantUS5545806
 US5545807
 WO9713852
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.