EP2288613 - PHENYL-SUBSTITUTED 2-IMINO-3-METHYL PYRROLO PYRIMIDINONE COMPOUNDS AS BACE-1 INHIBITORS, COMPOSITIONS, AND THEIR USE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 19.05.2017 Database last updated on 22.08.2024 | Most recent event Tooltip | 06.03.2020 | Lapse of the patent in a contracting state New state(s): TR | published on 08.04.2020 [2020/15] | Applicant(s) | For all designated states Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2016/28] |
Former [2012/33] | For all designated states Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway NJ 07065-0907 / US | ||
Former [2011/09] | For all designated states Schering Corporation 2000 Galloping Hill Road Kenilworth, NJ 07033 / US | Inventor(s) | 01 /
STAMFORD, Andrew, W. 27 Overlook Road Chatham Township NJ 07928 / US | 02 /
ZHU, Zhaoning 6 Cypress Court Plainsboro NJ 08536 / US | 03 /
MANDAL, Mihirbaran 181 Spruce Mill Lane 181 Scotch Plains NJ 07076 / US | 04 /
WU, Yusheng 235 East 40th Street Apt. 20c New York NY 10016 / US | 05 /
CUMMING, Jared, N. 417 Center Street Garwood NJ 07027 / US | 06 /
LIU, Xiaoxiang 551 Cleveland Avenue River Vale NJ 07675 / US | 07 /
LI, Guoqing 19 Waters Lane Belle Mead NJ 08502 / US | 08 /
ISERLOH, Ulrich 1110 Park Avenue Apt. 2l Hoboken NJ 07030 / US | [2011/09] | Representative(s) | Jaap, David Robert, et al Merck Sharp & Dohme Corp. 120 Moorgate London, EC2M 6UR / GB | [N/P] |
Former [2016/28] | Buchan, Gavin MacNicol Merck & Co., Inc. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | ||
Former [2011/09] | Buchan, Gavin MacNicol Merck & Co., Inc. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | Application number, filing date | 09734237.2 | 21.04.2009 | [2011/09] | WO2009US41202 | Priority number, date | US20080047006P | 22.04.2008 Original published format: US 47006 P | [2016/26] |
Former [2011/09] | US20080047006 | 22.04.2008 | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2009131975 | Date: | 29.10.2009 | Language: | EN | [2009/44] | Type: | A1 Application with search report | No.: | EP2288613 | Date: | 02.03.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 29.10.2009 takes the place of the publication of the European patent application. | [2011/09] | Type: | B1 Patent specification | No.: | EP2288613 | Date: | 13.07.2016 | Language: | EN | [2016/28] | Search report(s) | International search report - published on: | EP | 29.10.2009 | Classification | IPC: | C07D487/04, A61P25/28, A61K31/519 | [2011/09] | CPC: |
C07D487/04 (EP,US);
A61P11/02 (EP);
A61P13/12 (EP);
A61P25/00 (EP);
A61P25/16 (EP);
A61P25/28 (EP);
A61P27/00 (EP);
A61P27/06 (EP);
A61P3/10 (EP);
A61P31/00 (EP);
A61P43/00 (EP);
A61P7/08 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2016/28] |
Former [2011/09] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR | Extension states | AL | 22.11.2010 | BA | 22.11.2010 | RS | 22.11.2010 | Title | German: | PHENYLSUBSTITUIERTE 2-IMINO-3-METHYLPYRROLOPYRIMIDINONVERBINDUNGEN ALS BACE-1-INHIBITOREN, ZUSAMMENSETZUNGEN UND DEREN VERWENDUNG | [2011/09] | English: | PHENYL-SUBSTITUTED 2-IMINO-3-METHYL PYRROLO PYRIMIDINONE COMPOUNDS AS BACE-1 INHIBITORS, COMPOSITIONS, AND THEIR USE | [2011/09] | French: | COMPOSES DE 2-IMINO-3-METHYL-PYRROLO PYRIMIDINONE SUBSTITUES PAR PHENYLE UTILISES EN TANT QU INHIBITEURS BACE-1, COMPOSITIONS ET UTILISATION ASSOCIEES | [2011/09] | Entry into regional phase | 22.11.2010 | National basic fee paid | 22.11.2010 | Designation fee(s) paid | 22.11.2010 | Examination fee paid | Examination procedure | 08.11.2010 | Amendment by applicant (claims and/or description) | 22.11.2010 | Examination requested [2011/09] | 16.06.2014 | Despatch of a communication from the examining division (Time limit: M04) | 15.10.2014 | Reply to a communication from the examining division | 11.03.2015 | Despatch of a communication from the examining division (Time limit: M06) | 16.09.2015 | Reply to a communication from the examining division | 03.02.2016 | Communication of intention to grant the patent | 26.05.2016 | Receipt of the translation of the claim(s) | 27.05.2016 | Fee for grant paid | 27.05.2016 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 16.06.2014 | Opposition(s) | 18.04.2017 | No opposition filed within time limit [2017/25] | Fees paid | Renewal fee | 06.04.2011 | Renewal fee patent year 03 | 21.03.2012 | Renewal fee patent year 04 | 26.03.2013 | Renewal fee patent year 05 | 26.03.2014 | Renewal fee patent year 06 | 08.04.2015 | Renewal fee patent year 07 | 30.03.2016 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 21.04.2009 | AT | 13.07.2016 | BE | 13.07.2016 | CY | 13.07.2016 | CZ | 13.07.2016 | DK | 13.07.2016 | EE | 13.07.2016 | ES | 13.07.2016 | FI | 13.07.2016 | HR | 13.07.2016 | IT | 13.07.2016 | LT | 13.07.2016 | LV | 13.07.2016 | MC | 13.07.2016 | MK | 13.07.2016 | NL | 13.07.2016 | PL | 13.07.2016 | RO | 13.07.2016 | SE | 13.07.2016 | SI | 13.07.2016 | SK | 13.07.2016 | TR | 13.07.2016 | BG | 13.10.2016 | NO | 13.10.2016 | GR | 14.10.2016 | IS | 13.11.2016 | PT | 14.11.2016 | [2020/15] |
Former [2019/51] | HU | 21.04.2009 | |
AT | 13.07.2016 | ||
BE | 13.07.2016 | ||
CY | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
MC | 13.07.2016 | ||
MK | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SI | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2019/46] | HU | 21.04.2009 | |
AT | 13.07.2016 | ||
BE | 13.07.2016 | ||
CY | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
MC | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SI | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2019/31] | HU | 21.04.2009 | |
AT | 13.07.2016 | ||
BE | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
MC | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SI | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2018/06] | AT | 13.07.2016 | |
BE | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
MC | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SI | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2017/37] | AT | 13.07.2016 | |
BE | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SI | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2017/31] | AT | 13.07.2016 | |
BE | 13.07.2016 | ||
CZ | 13.07.2016 | ||
DK | 13.07.2016 | ||
EE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
RO | 13.07.2016 | ||
SE | 13.07.2016 | ||
SK | 13.07.2016 | ||
BG | 13.10.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2017/13] | AT | 13.07.2016 | |
BE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
LV | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
SE | 13.07.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2017/11] | AT | 13.07.2016 | |
BE | 13.07.2016 | ||
ES | 13.07.2016 | ||
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
SE | 13.07.2016 | ||
NO | 13.10.2016 | ||
GR | 14.10.2016 | ||
IS | 13.11.2016 | ||
PT | 14.11.2016 | ||
Former [2017/10] | BE | 13.07.2016 | |
FI | 13.07.2016 | ||
HR | 13.07.2016 | ||
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
NL | 13.07.2016 | ||
PL | 13.07.2016 | ||
SE | 13.07.2016 | ||
NO | 13.10.2016 | ||
IS | 13.11.2016 | ||
Former [2017/09] | FI | 13.07.2016 | |
IT | 13.07.2016 | ||
LT | 13.07.2016 | ||
NL | 13.07.2016 | ||
NO | 13.10.2016 | ||
Former [2017/07] | LT | 13.07.2016 | Cited in | International search | [ID]WO2006138264 (SCHERING CORP [US], et al) [ID] 1,18,20,29,34 * page 16, line 14 * * page 34, line 20 - line 23 ** claims 1,17,29,32,35,36 * |