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Extract from the Register of European Patents

EP About this file: EP2344202

EP2344202 - MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.01.2021
Database last updated on 28.03.2026
FormerThe patent has been granted
Status updated on  07.02.2020
FormerGrant of patent is intended
Status updated on  26.09.2019
FormerExamination is in progress
Status updated on  09.12.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
CHILDREN'S MEDICAL CENTER CORPORATION
55 Shattuck Street
Boston, Massachusetts 02115 / US
[2011/29]
Inventor(s)01 / LENCER, Wayne I.
60 Louder Lane
Jamaica Plain MA 02130 / US
02 / CHINNAPEN, Daniel JF
3 Primrose Circle
Quincy, Massachusetts 02169 / US
 [2020/11]
Former [2011/29]01 / LENCER, Wayne, I.
60 Louder Lane
Jamaica Plain MA 02130 / US
02 / CHINNAPEN, Daniel, JF
120 Holmes Street Unit 220
Quincy, MA 02171 / US
Representative(s)EIP
Fairfax House
15 Fulwood Place
London WC1V 6HU / GB
[N/P]
Former [2020/11]Bridle, Andrew Barry, et al
Bridle
Intellectual Property Limited
6F Thomas Way
Lakesview Internat. Business Park
Canterbury, Kent CT3 4JZ / GB
Former [2011/29]Bridle, Andrew Barry, et al
Bridle Intellectual Property Limited 6F Thomas Way Lakesview Internat. Business Park
Canterbury, Kent CT3 4JZ / GB
Application number, filing date09744219.804.09.2009
[2011/29]
WO2009US04986
Priority number, dateUS20080191468P08.09.2008         Original published format: US 191468 P
[2011/29]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010027479
Date:11.03.2010
Language:EN
[2010/10]
Type: A2 Application without search report 
No.:EP2344202
Date:20.07.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 11.03.2010 takes the place of the publication of the European patent application.
[2011/29]
Type: B1 Patent specification 
No.:EP2344202
Date:11.03.2020
Language:EN
[2020/11]
Search report(s)International search report - published on:EP07.10.2010
ClassificationIPC:A61K47/54, A61K47/61
[2019/41]
CPC:
A61K47/549 (EP,US); A61K31/4164 (EP,US); A61K38/26 (EP,US);
A61K39/15 (US); A61K47/543 (EP,US); A61K47/544 (US);
A61K47/61 (EP,US); A61P43/00 (EP); C12N7/00 (US);
C12N2720/12322 (US); C12N2720/12334 (US) (-)
Former IPC [2011/29]A61K47/48
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2020/11]
Former [2011/29]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:MUKOSALE ABGABE VON THERAPEUTISCHEN MOLEKÜLEN, PROTEINEN ODER TEILCHEN, DIE AN CERAMID-LIPID GEKOPPELT SIND[2011/29]
English:MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS[2011/29]
French:ADMINISTRATION MUCOSALE DE MOLÉCULES, PROTÉINES OU PARTICULES THÉRAPEUTIQUES COUPLÉES À DES LIPIDES CÉRAMIDES[2019/41]
Former [2011/29]ADMINISTRATION MUCOSALE DE MOLÉCULES, PROTÉINES OU PARTICULES THÉRAPEUTIQUES COUPLÉES À DES LIPIDES CÉRAMIQUES
Entry into regional phase06.04.2011National basic fee paid 
06.04.2011Designation fee(s) paid 
06.04.2011Examination fee paid 
Examination procedure06.04.2011Amendment by applicant (claims and/or description)
06.04.2011Examination requested  [2011/29]
31.05.2016Despatch of a communication from the examining division (Time limit: M06)
06.12.2016Reply to a communication from the examining division
04.09.2017Despatch of a communication from the examining division (Time limit: M06)
05.03.2018Reply to a communication from the examining division
01.10.2018Despatch of a communication from the examining division (Time limit: M04)
08.02.2019Reply to a communication from the examining division
27.09.2019Communication of intention to grant the patent
31.01.2020Fee for grant paid
31.01.2020Fee for publishing/printing paid
31.01.2020Receipt of the translation of the claim(s)
Divisional application(s)EP20159473.6  / EP3741391
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  31.05.2016
Opposition(s)14.12.2020No opposition filed within time limit [2021/07]
Fees paidRenewal fee
23.11.2011Renewal fee patent year 03
25.09.2012Renewal fee patent year 04
27.09.2013Renewal fee patent year 05
29.09.2014Renewal fee patent year 06
28.09.2015Renewal fee patent year 07
27.09.2016Renewal fee patent year 08
27.09.2017Renewal fee patent year 09
27.09.2018Renewal fee patent year 10
27.09.2019Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
30.09.201103   M06   Fee paid on   23.11.2011
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.09.2009
AT11.03.2020
CY11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
MK11.03.2020
MT11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
TR11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
CH30.09.2020
LI30.09.2020
[2022/32]
Former [2022/27]HU04.09.2009
AT11.03.2020
CY11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
MT11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
TR11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
CH30.09.2020
LI30.09.2020
Former [2022/26]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
TR11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
CH30.09.2020
LI30.09.2020
Former [2021/37]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
CH30.09.2020
LI30.09.2020
Former [2021/36]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
LU04.09.2020
BE30.09.2020
Former [2021/27]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
LU04.09.2020
Former [2021/23]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
MC11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2021/11]AT11.03.2020
CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
PL11.03.2020
RO11.03.2020
SE11.03.2020
SI11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2021/08]CZ11.03.2020
DK11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
RO11.03.2020
SE11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2020/50]CZ11.03.2020
EE11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
RO11.03.2020
SE11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2020/49]CZ11.03.2020
FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
RO11.03.2020
SE11.03.2020
SK11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2020/48]FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
RO11.03.2020
SE11.03.2020
SM11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
PT05.08.2020
Former [2020/47]FI11.03.2020
HR11.03.2020
LT11.03.2020
LV11.03.2020
NL11.03.2020
SE11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
Former [2020/46]FI11.03.2020
HR11.03.2020
LV11.03.2020
NL11.03.2020
SE11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
IS11.07.2020
Former [2020/45]FI11.03.2020
HR11.03.2020
LV11.03.2020
NL11.03.2020
SE11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
Former [2020/39]FI11.03.2020
HR11.03.2020
LV11.03.2020
SE11.03.2020
BG11.06.2020
NO11.06.2020
GR12.06.2020
Former [2020/38]FI11.03.2020
HR11.03.2020
LV11.03.2020
SE11.03.2020
NO11.06.2020
GR12.06.2020
Former [2020/37]FI11.03.2020
HR11.03.2020
LV11.03.2020
SE11.03.2020
NO11.06.2020
Former [2020/35]FI11.03.2020
NO11.06.2020
Cited inInternational search[I] WO9943356  (HSC RES DEV LP et al.) [I] 1-67 * page 51 * * figure 6 *
 [I] WO9401138  (OREGON STATE et al.) [I] 1-67 * example 7 *
 [I] WO9915201  (SLOAN KETTERING INST CANCER et al.) [I] 1-67 * claim - *
 [IP] WO2008111916  (AGENCY SCIENCE TECH & RES et al.) [IP] 1-67 * example . * * figure 14/14 *
 [I]   L. FRANCHINI ET AL: "Synthesis of a fluorescent sulfatide for the study of CD1 antigen binding properties.", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2004, no. 23, December 2004 (2004-12-01), pages 4755 - 4761, XP002596009, ISSN: 1099-0690, DOI: 10.1002ejoc.200400398 [I] 1-67 * figure 1 *

DOI:   http://dx.doi.org/10.1002/ejoc.200400398
 [I]   CHIGORNO V ET AL: "Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture", FEBS LETTERS, vol. 263, no. 2, 24 April 1990 (1990-04-24), pages 329 - 331, XP025601899, ISSN: 0014-5793, [retrieved on 19900424], DOI: 10.1016/0014-5793(90)81406-E [I] 1-67 * page 329, column l * * page 330, column l *

DOI:   http://dx.doi.org/10.1016/0014-5793(90)81406-E
 [I]   BAGAI S ET AL: "Reconstituted Sendai virus envelopes as biological carriers: dual role of F protein in binding and fusion with liver cells", BIOCHIMICA ET BIOPHYSICA ACTA. BIOMEMBRANES, vol. 1152, no. 1, 10 October 1993 (1993-10-10), pages 15 - 25, XP023352288, ISSN: 0005-2736, [retrieved on 19931010], DOI: 10.1016/0005-2736(93)90226-P [I] 1-67 * page 21, column r, paragraph 1; figure 6 * * page 22; table III *

DOI:   http://dx.doi.org/10.1016/0005-2736(93)90226-P
 [IP]   PANASIEWICZ M ET AL: "Preparation of Alexa Fluor 350-conjugated nonradioactive or <3>H-labeled GM1 ganglioside derivatives with different ceramides", ANALYTICAL BIOCHEMISTRY, vol. 385, no. 1, 1 February 2009 (2009-02-01), pages 168 - 170, XP025838530, ISSN: 0003-2697, [retrieved on 20081021], DOI: 10.1016/J.AB.2008.10.017 [IP] 1-67 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ab.2008.10.017
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.