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EP About this file: EP2297202

EP2297202 - ANTI-IL-6/IL-6R ANTIBODIES AND METHODS OF USE THEREOF [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 18.11.2016 Database last updated on 13.11.2024
Most recent event Tooltip	20.07.2018	Lapse of the patent in a contracting state New state(s): MT	published on 22.08.2018 [2018/34]
Applicant(s)	For all designated states NovImmune SA 14 ch. Des Aulx Plan-Les Ouates 1228 Geneva / CH
	[2016/02]
Former [2012/08]	For all designated states NovImmune SA 14 ch. Des Aulx Plan-Les Ouates 1228 Geneva / CH
Former [2011/12]	For all designated states Novimmune Sa 14 Ch. Des Aulx 1228 Plan-les-Ouates Geneva / CH
Inventor(s)	01 / FERLIN, Walter Villa de L'archet 217 Rue de L'archet F-74140 Saint Cergues / FR
	02 / KOSCO-VILBOIS, Marie Le Cret F-74270 Minzier / FR
	03 / ELSON, Greg 222 Route De Bossey F-74160 Collonges sous Saleve / FR
	04 / LEGER, Olivier 603 Route Des Luches F-74800 St.-Sixt / FR
	05 / GUILHOT, Florence 9 Avenue de Ternier Residence L'Ambassade F-74160 Saint Julien en Genevois / FR
	[2016/02]
Former [2011/29]	01 / FERLIN, Walter Villa de L'archet 217 Rue de L'archet F-74140 Saint Cergues / FR
	02 / KOSCO-VILBOIS, Marie Le Cret F-74270 Minzier / FR
	03 / ELSON, Greg 222 Route De Bossey F-74160 Collonges sous Saleve / FR
	04 / LEGER, Olivier 603 Route Des Luches F-74800 St.-Sixt / FR
	05 / GUILHOT, Florence 9 Avenue de Ternier Residence L'Ambassade F-74160 Saint Julien en Genevois / FR
Former [2011/12]	01 / FERLIN, Walter Villa de L'archet 217 Rue de L'archet F-74140 Saint Cergues / FR
	02 / KOSCO-VILBOIS, Marie Le Cret F-74270 Minzier / FR
	03 / ELSON, Greg 222 Route De Bossey F-74160 Collonges Sous Saleve / FR
	04 / LEGER, Olivier 603 Route Des Luches F-74800 St.-Sixt / FR
	05 / GUILHOT, Florence 9 Avenue de Ternier Residence L'Ambassade F-74160 Saint Julien en Genevois / FR
Representative(s)	Cooley (UK) LLP 22 Bishopsgate London EC2N 4BQ / GB
	[N/P]
Former [2016/02]	Cooley (UK) LLP Dashwood 69 Old Broad Street London EC2M 1QS / GB
Former [2013/15]	Mintz Levin Cohn Ferris Glovsky and Popeo LLP Alder Castle 10 Noble Street London EC2V 7JX / GB
Former [2011/12]	Clarke, Victoria, et al Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP Alder Castle 10 Noble Street London EC2V 7JX / GB
Application number, filing date	09747432.4	13.05.2009
	[2011/12]
	WO2009US43734
Priority number, date	US20080194156	25.09.2008 Original published format: US 194156
	US20080127403	13.05.2008 Original published format: US 127403
	[2011/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2009140348
	Date:	19.11.2009
	Language:	EN
	[2009/47]
	Type:	A2 Application without search report
	No.:	EP2297202
	Date:	23.03.2011
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 19.11.2009 takes the place of the publication of the European patent application.
	[2011/12]
	Type:	B1 Patent specification
	No.:	EP2297202
	Date:	13.01.2016
	Language:	EN
	[2016/02]
Search report(s)	International search report - published on:	US	07.01.2010
	(Supplementary) European search report - dispatched on:	EP	25.09.2012
Classification	IPC:	C07K16/24, C12P21/08	[2011/12]
	CPC:	C07K16/2866 (EP,US); A61P1/04 (EP); A61P11/06 (EP); A61P17/06 (EP); A61P19/02 (EP); A61P25/00 (EP); (+) A61P25/28 (EP); A61P29/00 (EP); A61P35/00 (EP); A61P37/00 (EP); A61P37/06 (EP); C07K16/248 (EP,US); C07K2317/21 (EP,US); C07K2317/32 (EP,US); C07K2317/33 (US); C07K2317/56 (EP,US); C07K2317/565 (EP,US); C07K2317/73 (EP,US); C07K2317/76 (EP,US); C07K2317/92 (EP,US) (-)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2016/02]
Former [2011/12]	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR
Title	German:	ANTI-IL-6/IL-6R-ANTIKÖRPER UND VERFAHREN ZU IHRER VERWENDUNG	[2011/12]
	English:	ANTI-IL-6/IL-6R ANTIBODIES AND METHODS OF USE THEREOF	[2011/12]
	French:	ANTICORPS ANTI-IL-6/IL-6R ET PROCÉDÉS D'UTILISATION	[2011/12]
Entry into regional phase	26.11.2010	National basic fee paid
	26.11.2010	Search fee paid
	26.11.2010	Designation fee(s) paid
	26.11.2010	Examination fee paid
Examination procedure	26.11.2010	Examination requested [2011/12]
	18.04.2013	Amendment by applicant (claims and/or description)
	04.11.2013	Despatch of a communication from the examining division (Time limit: M06)
	06.05.2014	Reply to a communication from the examining division
	02.07.2015	Communication of intention to grant the patent
	04.11.2015	Fee for grant paid
	04.11.2015	Fee for publishing/printing paid
	23.11.2015	Information about intention to grant a patent
	23.11.2015	Receipt of the translation of the claim(s)
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 04.11.2013
Opposition(s)	14.10.2016	No opposition filed within time limit [2016/51]
Fees paid	Renewal fee
	25.05.2011	Renewal fee patent year 03
	25.05.2012	Renewal fee patent year 04
	28.05.2013	Renewal fee patent year 05
	29.05.2014	Renewal fee patent year 06
	21.05.2015	Renewal fee patent year 07
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	13.05.2009
	CY	13.01.2016
	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	MC	13.01.2016
	MK	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SI	13.01.2016
	SK	13.01.2016
	TR	13.01.2016
	BG	13.04.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
	MT	31.05.2016
	[2018/32]
Former [2018/29]	HU	13.05.2009
	CY	13.01.2016
	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	MC	13.01.2016
	MK	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SI	13.01.2016
	SK	13.01.2016
	TR	13.01.2016
	BG	13.04.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
Former [2018/28]	HU	13.05.2009
	CY	13.01.2016
	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	MC	13.01.2016
	MK	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SI	13.01.2016
	SK	13.01.2016
	BG	13.04.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
Former [2017/15]	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SI	13.01.2016
	SK	13.01.2016
	BG	13.04.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
Former [2017/10]	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SK	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
Former [2016/50]	CZ	13.01.2016
	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	PL	13.01.2016
	RO	13.01.2016
	SK	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
	BE	31.05.2016
Former [2016/49]	EE	13.01.2016
	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	PL	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
	BE	31.05.2016
Former [2016/39]	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	LV	13.01.2016
	PL	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
	BE	31.05.2016
Former [2016/38]	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	PL	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	IS	13.05.2016
	PT	13.05.2016
	BE	31.05.2016
Former [2016/36]	FI	13.01.2016
	HR	13.01.2016
	LT	13.01.2016
	PL	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
	BE	31.05.2016
Former [2016/35]	FI	13.01.2016
	HR	13.01.2016
	NO	13.04.2016
	GR	14.04.2016
Documents cited:	Search	[AD]WO9713781 (YEDA RES & DEV [IL], et al) [AD] 1-15 * page 17 *;
		[I]WO2007076927 (MERCK PATENT GMBH [DE], et al) [I] 1-15 * figure 8; examples 6,7 * * page 27 *;
		[IP]WO2008065384 (ASTRAZENECA AB [SE], et al) [IP] 1-15 * page 80, line 32 - line 35 * * example 5 *;
		[A] - JAKOBOVITS AYA ET AL, "From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 25, no. 10, doi:10.1038/NBT1337, ISSN 1087-0156, (20071001), pages 1134 - 1143, (20071005), XP002556637 [A] 1-15 * page 1336 * DOI: http://dx.doi.org/10.1038/nbt1337
		[A] - GAILLARD J P ET AL, "Identification of a Novel Antigenic Structure of the Human Receptor for Interleukin-6 Involved in the Interaction with the Glycoprotein 130 Chain", IMMUNOLOGY, BLACKWELL PUBLISHING, OXFORD, GB, (19960901), vol. 89, no. 1, doi:10.1046/J.1365-2567.1996.D01-709.X, ISSN 0019-2805, pages 135 - 141, XP008145320 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1046/j.1365-2567.1996.d01-709.x
	International search	[A]US2005074821 (WILD KENNETH D [US], et al);
		[Y]US2007280945 (STEVENS SEAN [US], et al);
		[Y] - GAILLARD, J. P ET AL., "Identification of a Novel Antigenic Structure of the Human Receptor for Interleukin-6 Involved in the Interaction with the Glycoprotein 130 Chain.", IMMUNOLOGY., (199609), vol. 89, no. 1, pages 135 - 141, XP008145320 DOI: http://dx.doi.org/10.1046/j.1365-2567.1996.d01-709.x
		[Y] - GRUBE, B. J. ET AL., "Identification of a Regulatory Domain of the Interieukin-6 Receptor.", THE JOUMAL OF BIOLOGICAL CHEMISTRY., (199408), vol. 269, no. 32, pages 20791 - 20797, XP002054920
	Examination	- KALAI M ET AL, "Analysis of the mechanism of action of anti-human interleukin-6 and anti-human interleukin-6 receptor-neutralising monoclonal antibodies", EUROPEAN JOURNAL OF BIOCHEMISTRY, PUBLISHED BY SPRINGER-VERLAG ON BEHALF OF THE FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES, (19971101), vol. 249, no. 3, doi:10.1111/J.1432-1033.1997.T01-2-00690.X, ISSN 0014-2956, pages 690 - 700, XP002551736 DOI: http://dx.doi.org/10.1111/j.1432-1033.1997.t01-2-00690.x
		- GAILLARD J P ET AL, "Identification of a Novel Antigenic Structure of the Human Receptor for Interleukin-6 Involved in the Interaction with the Glycoprotein 130 Chain", IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, (19960901), vol. 89, no. 1, doi:10.1046/J.1365-2567.1996.D01-709.X, ISSN 0019-2805, pages 135 - 141, XP008145320 DOI: http://dx.doi.org/10.1046/j.1365-2567.1996.d01-709.x

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