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Extract from the Register of European Patents

EP About this file: EP2300043

EP2300043 - ANALGESIC EFFECTS OF PEPTIDE TOXIN APETX2 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.08.2013
Database last updated on 17.09.2024
Most recent event   Tooltip03.07.2015Lapse of the patent in a contracting state
New state(s): MK		published on 05.08.2015  [2015/32]
Applicant(s)For all designated states
Centre National de la Recherche Scientifique (C.N.R.S.)
3 rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université Nice Sophia Antipolis
Grand Château Parc Valrose 28, avenue Valrose
06108 Nice Cedex 2 / FR
[N/P]
Former [2011/13]For all designated states
Centre National de la Recherche Scientifique - CNRS
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Université Nice Sophia Antipolis
Grand Château Parc Valrose 28, avenue Valrose
06108 Nice Cedex 2 / FR
Inventor(s)01 / DEVAL, Emmanuel
212 avenue Georges Pompidou
Résidence Parc Monceau, bât. A1, appt.209
F-06220 Golfe Juan / FR
02 / DIOCHOT, Sylvie
12 Placettes des Eglantiers
F-06560 Valbonne / FR
03 / LAZDUNSKI, Michel
21 avenue Colombo
F-06000 Nice / FR
04 / LINGUEGLIA, Eric
37 avenue Edith Cavell
F-06000 Nice / FR
05 / NOEL, Jacques
17 avenue de Gairault
F-06100 Nice / FR
 [2012/42]
Former [2011/19]01 / DEVAL, Emmanuel
212 avenue Georges Pompidou Résidence Parc Monceau, bât. A1, appt.209
F-06220 Golfe Juan / FR
02 / DIOCHOT, Sylvie
12 Placettes des Eglantiers
F-06560 Valbonne / FR
03 / LAZDUNSKI, Michel
21 avenue Colombo
F-06000 Nice / FR
04 / LINGUEGLIA, Eric
37 avenue Edith Cavell
F-06000 Nice / FR
05 / NOEL, Jacques
17 avenue de Gairault
F-06100 Nice / FR
Former [2011/13]01 / DEVAL, Emmanuel
212 avenue Georges Pompidou
F-06220 Golfe Juan / FR
02 / DIOCHOT, Sylvie
12 Placettes des Eglantiers
F-06560 Valbonne / FR
03 / LAZDUNSKI, Michel
21 avenue Colombo
F-06000 Nice / FR
04 / LINGUEGLIA, Eric
37 avenue Edith Cavell
F-06000 Nice / FR
05 / NOEL, Jacques
17 avenue de Gairault
F-06100 Nice / FR
Representative(s)Patarin, Stephanie
Novagraaf Technologies
122, rue Edouard Vaillant
92593 Levallois-Perret Cedex / FR
[N/P]
Former [2012/42]Patarin, Stephanie
Novagraaf Technologies 122, rue Edouard Vaillant
92593 Levallois-Perret Cedex / FR
Former [2011/13]Patarin, Stephanie
Novagraaf Technologies 122, rue Edouard Vaillant
92593 Levallois-Perret Cedex / FR
Application number, filing date09757702.704.06.2009
[2011/13]
WO2009FR00657
Priority number, dateFR2008000315806.06.2008         Original published format: FR 0803158
[2011/13]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2009147326
Date:10.12.2009
Language:FR
[2009/50]
Type: A1 Application with search report 
No.:EP2300043
Date:30.03.2011
Language:FR
The application published by WIPO in one of the EPO official languages on 10.12.2009 takes the place of the publication of the European patent application.
[2011/13]
Type: B1 Patent specification 
No.:EP2300043
Date:17.10.2012
Language:FR
[2012/42]
Search report(s)International search report - published on:EP10.12.2009
ClassificationIPC:A61K38/16, A61P29/00, A61P17/04
[2011/13]
CPC:
A61K38/16 (EP,US); A61P17/04 (EP); A61P19/00 (EP);
A61P27/02 (EP); A61P29/00 (EP); A61P31/00 (EP);
A61P35/00 (EP); A61P9/00 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/13]
TitleGerman:ANALGETISCHE WIRKUNGEN VON PEPTIDTOXIN APETX2[2011/13]
English:ANALGESIC EFFECTS OF PEPTIDE TOXIN APETX2[2011/13]
French:EFFETS ANALGESIQUES DE LA TOXINE PEPTIDIQUE APETX2[2011/13]
Entry into regional phase15.12.2010National basic fee paid 
15.12.2010Designation fee(s) paid 
15.12.2010Examination fee paid 
Examination procedure15.12.2010Examination requested  [2011/13]
10.02.2011Amendment by applicant (claims and/or description)
30.06.2011Despatch of a communication from the examining division (Time limit: M04)
07.10.2011Reply to a communication from the examining division
22.05.2012Communication of intention to grant the patent
31.08.2012Fee for grant paid
31.08.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  30.06.2011
Opposition(s)18.07.2013No opposition filed within time limit [2013/39]
Fees paidRenewal fee
29.06.2011Renewal fee patent year 03
27.06.2012Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY17.10.2012
CZ17.10.2012
EE17.10.2012
HR17.10.2012
LT17.10.2012
LV17.10.2012
MK17.10.2012
MT17.10.2012
RO17.10.2012
SI17.10.2012
SK17.10.2012
BG17.01.2013
IS17.02.2013
[2015/32]
Former [2015/13]CY17.10.2012
CZ17.10.2012
EE17.10.2012
HR17.10.2012
LT17.10.2012
LV17.10.2012
MT17.10.2012
RO17.10.2012
SI17.10.2012
SK17.10.2012
BG17.01.2013
IS17.02.2013
Former [2013/52]CY17.10.2012
CZ17.10.2012
EE17.10.2012
HR17.10.2012
LT17.10.2012
LV17.10.2012
RO17.10.2012
SI17.10.2012
SK17.10.2012
BG17.01.2013
IS17.02.2013
Former [2013/37]CZ17.10.2012
EE17.10.2012
HR17.10.2012
LT17.10.2012
LV17.10.2012
RO17.10.2012
SI17.10.2012
SK17.10.2012
BG17.01.2013
IS17.02.2013
Former [2013/35]CZ17.10.2012
EE17.10.2012
HR17.10.2012
LT17.10.2012
LV17.10.2012
SI17.10.2012
SK17.10.2012
BG17.01.2013
IS17.02.2013
Former [2013/34]HR17.10.2012
LT17.10.2012
LV17.10.2012
SI17.10.2012
BG17.01.2013
IS17.02.2013
Former [2013/26]HR17.10.2012
LT17.10.2012
LV17.10.2012
SI17.10.2012
IS17.02.2013
Former [2013/23]HR17.10.2012
LT17.10.2012
LV17.10.2012
IS17.02.2013
Former [2013/22]LT17.10.2012
IS17.02.2013
Former [2013/20]LT17.10.2012
Cited inInternational search[PX]US2008181881  (CHEN CHIH-CHENG [TW], et al) [PX] 1-11 * page 6, paragraph 25 *;
 [PX]  - DEVAL EMMANUEL ET AL, "ASIC3, a sensor of acidic and primary inflammatory pain", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, (200811), vol. 27, no. 22, ISSN 0261-4189, pages 3047 - 3055, XP009110553 [PX] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1038/emboj.2008.213
 [PY]  - CHEN CHIH-CHENG, "ASIC3 and muscle pain", NOVEL TRENDS IN BRAIN SCIENCE:BRAIN IMAGING, LEARNING AND MEMORY, STRESS AND FEAR, AND PAIN SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES, (2008), ISSN 978-4-431-73241-9(H), pages 225 - 232, XP002509971 [PY] 1-11 * the whole document *
 [DY]  - DIOCHOT S ET AL, "A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons", EMBO JOURNAL 20040407 GB, (20040407), vol. 23, no. 7, ISSN 0261-4189, pages 1516 - 1525, XP009110554 [DY] 1-11 * abstract * * page 1522, column R, paragraphs 3,4 - page 1523, column L, paragraph 1 * * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.emboj.7600177
 [Y]  - CHEN C -C ET AL, "A role for ASIC3 in the modulation of high-intensity pain stimuli", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 20020625 US, (20020625), vol. 99, no. 13, ISSN 0027-8424, pages 8992 - 8997, XP002509972 [Y] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1073/PNAS.122245999
 [Y]  - TOMOHIRO HONMA ET AL, "Peptide Toxins in Sea Anemones: Structural and Functional Aspects", MARINE BIOTECHNOLOGY, SPRINGER-VERLAG, NE, (20060101), vol. 8, no. 1, ISSN 1436-2236, pages 1 - 10, XP019368183 [Y] 1-11 * abstract * * page 5, column R, paragraph L - page 6, column L, paragraph 1 *
 [Y]  - MOLLIVER DEREK C ET AL, "ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons", MOLECULAR PAIN, BIOMED CENTRAL, LONDON, GB, (20051123), vol. 1, no. 1, ISSN 1744-8069, page 35, XP021011227 [Y] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1186/1744-8069-1-35
 [Y]  - VOILLEY N ET AL, "Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors", JOURNAL OF NEUROSCIENCE 20011015 US, (20011015), vol. 21, no. 20, ISSN 0270-6474, pages 8026 - 8033, XP002509973 [Y] 1-11 * the whole document *
 [Y]  - DIOCHOT ET AL, "Peptides inhibitors of acid-sensing ion channels", TOXICON, ELMSFORD, NY, US, (20070126), vol. 49, no. 2, ISSN 0041-0101, pages 271 - 284, XP005738071 [Y] 1-11 * abstract * * page 273, column R, paragraph L - page 274, column R, paragraph 1 * * page 276, column L, paragraph L - column R, paragraph 1 * * the whole document *

DOI:   http://dx.doi.org/10.1016/j.toxicon.2006.09.026
 [A]  - CHAGOT BENJAMIN ET AL, "Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels", PROTEIN SCIENCE, CAMBRIDGE UNIVERSITY PRESS, CAMBRIDGE, GB, (20050629), vol. 14, no. 8, ISSN 0961-8368, pages 2003 - 2010, XP009110558 [A] 1-11 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.