blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2379088

EP2379088 - TREATMENT OF LUNG AND PULMONARY DISEASES AND DISORDERS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.01.2019
Database last updated on 22.08.2024
FormerThe patent has been granted
Status updated on  26.01.2018
FormerGrant of patent is intended
Status updated on  23.05.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
DePuy Synthes Products, Inc.
325 Paramount Drive
Raynham, MA 02767-0350 / US
[2018/09]
Former [2011/43]For all designated states
Advanced Technologies and Regenerative Medicine, LLC
325 Paramount Drive
Raynham, MA 02767 / US
Inventor(s)01 / COLTER, David C.
208 Irvington Place
Hamilton New Jersey 08610 / US
02 / KIHM, Anthony J.
22E Chicopee Drive
Princeton New Jersey 08540 / US
03 / WARD, Christine K.
115 Tudor Court
Malvern Pennsylvania 19355 / US
04 / GOSIEWSKA, Anna
39 Red Fox Court
Skillman New Jersey 08558 / US
 [2011/43]
Representative(s)Wise, Daniel Joseph, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2018/09]
Former [2011/43]Hallybone, Huw George, et al
Carpmaels & Ransford One Southampton Row London
WC1B 5HA / GB
Application number, filing date09796901.819.12.2009
[2018/09]
WO2009US68881
Priority number, dateUS20080139425P19.12.2008         Original published format: US 139425 P
[2011/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010071864
Date:24.06.2010
Language:EN
[2010/25]
Type: A1 Application with search report 
No.:EP2379088
Date:26.10.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 24.06.2010 takes the place of the publication of the European patent application.
[2011/43]
Type: B1 Patent specification 
No.:EP2379088
Date:28.02.2018
Language:EN
[2018/09]
Search report(s)International search report - published on:EP24.06.2010
ClassificationIPC:A61K35/28, A61K35/51, C12N5/0775
[2017/17]
CPC:
C12N5/0605 (EP,CN,US); A61K35/51 (EP,CN,US); A61K35/42 (EP,CN,US);
A61K35/44 (EP,CN,US); A61K45/06 (EP,CN,US); A61L27/3834 (EP,CN,US);
A61P11/00 (EP); C12N5/0668 (EP,CN,US); A61K2035/124 (EP,CN,US);
A61K35/12 (EP,CN,US); A61L2430/22 (EP,CN,US) (-)
Former IPC [2011/43]A61K35/44, C12N5/073
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2018/09]
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:BEHANDLUNG VON LUNGEN UND PULMONALEN ERKRANKUNGEN UND STÖRUNGEN[2017/18]
English:TREATMENT OF LUNG AND PULMONARY DISEASES AND DISORDERS[2011/43]
French:TRAITEMENT DES MALADIES ET DES TROUBLES PULMONAIRES[2017/17]
Former [2011/43]BEHANDLUNG VON LUNGENKRANKHEITEN UND STÖRUNGEN
Former [2011/43]TRAITEMENT DES POUMONS ET DES MALADIES ET TROUBLES PULMONAIRES
Entry into regional phase19.07.2011National basic fee paid 
19.07.2011Designation fee(s) paid 
19.07.2011Examination fee paid 
Examination procedure19.07.2011Examination requested  [2011/43]
13.02.2012Amendment by applicant (claims and/or description)
06.08.2014Despatch of a communication from the examining division (Time limit: M06)
16.02.2015Reply to a communication from the examining division
20.04.2016Despatch of a communication from the examining division (Time limit: M04)
10.06.2016Reply to a communication from the examining division
24.05.2017Communication of intention to grant the patent
27.09.2017Fee for grant paid
27.09.2017Fee for publishing/printing paid
27.09.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.08.2014
Opposition(s)29.11.2018No opposition filed within time limit [2019/06]
Fees paidRenewal fee
12.12.2011Renewal fee patent year 03
11.12.2012Renewal fee patent year 04
12.12.2013Renewal fee patent year 05
11.12.2014Renewal fee patent year 06
10.12.2015Renewal fee patent year 07
13.12.2016Renewal fee patent year 08
12.12.2017Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.12.2009
AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
MK28.02.2018
NL28.02.2018
PT28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
TR28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
IS28.06.2018
[2020/33]
Former [2020/31]HU19.12.2009
AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
MK28.02.2018
NL28.02.2018
PT28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
TR28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2020/30]HU19.12.2009
AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
NL28.02.2018
PT28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
TR28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2020/27]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
NL28.02.2018
PT28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
TR28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2020/16]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
TR28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2019/40]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
MC28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2019/13]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SI28.02.2018
SK28.02.2018
SM28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2018/52]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SK28.02.2018
SM28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2018/51]AT28.02.2018
CY28.02.2018
CZ28.02.2018
DK28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SK28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2018/50]AT28.02.2018
CY28.02.2018
CZ28.02.2018
EE28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
NL28.02.2018
RO28.02.2018
SE28.02.2018
SK28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2018/40]AT28.02.2018
CY28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
LV28.02.2018
NL28.02.2018
SE28.02.2018
BG28.05.2018
NO28.05.2018
GR29.05.2018
Former [2018/37]CY28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
NL28.02.2018
NO28.05.2018
GR29.05.2018
Former [2018/35]CY28.02.2018
FI28.02.2018
HR28.02.2018
LT28.02.2018
NL28.02.2018
NO28.05.2018
Cited inInternational search[XI]WO2007124594  (CELL THERAPY TECHNOLOGIES INC [CA], et al) [X] 1-5,12-26 * figure 2; claims 1,2,6 * [I] 6-11;
 [XI]WO2007089063  (SAMSUNGN LIFE PUBLIC WELFARE F [KR], et al) [X] 1-5,12-26 * examples 1-7 * [I] 6-11;
 [XI]  - SUEBLINVONG VIRANUJ ET AL, "Derivation of lung epithelium from human cord blood-derived mesenchymal stem cells.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 1 APR 2008, (20080401), vol. 177, no. 7, ISSN 1535-4970, pages 701 - 711, XP002573715 [X] 1-6,12-26 * page 704, column r, paragraph l - page 705, column r, paragraph 2 * * page 704, column l, paragraph 2 * [I] 7-11

DOI:   http://dx.doi.org/10.1164/rccm.200706-859OC
 [I]  - WEISS DANIEL J, "Stem cells and cell therapies for cystic fibrosis and other lung diseases.", PULMONARY PHARMACOLOGY & THERAPEUTICS AUG 2008, (200808), vol. 21, no. 4, ISSN 1094-5539, pages 588 - 594, XP022932220 [I] 1-26 * page 591, column l, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/j.pupt.2007.11.004
Examination   - Deryl L. Troyer ET AL, "Concise Review: Wharton's Jelly-Derived Cells Are a Primitive Stromal Cell Population", Stem Cells, (20080301), vol. 26, no. 3, doi:10.1634/stemcells.2007-0439, ISSN 1066-5099, pages 591 - 599, XP055059242

DOI:   http://dx.doi.org/10.1634/stemcells.2007-0439
    - R S Rachakatla ET AL, "Development of human umbilical cord matrix stem cell-based gene therapy for experimental lung tumors", Cancer Gene Therapy, (20070629), vol. 14, no. 10, doi:10.1038/sj.cgt.7701077, ISSN 0929-1903, pages 828 - 835, XP055132471

DOI:   http://dx.doi.org/10.1038/sj.cgt.7701077
    - WEISS MARK L ET AL, "Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, (20060301), vol. 24, no. 3, doi:10.1634/STEMCELLS.2005-0330, ISSN 1066-5099, pages 781 - 792, XP002463574

DOI:   http://dx.doi.org/10.1634/stemcells.2005-0330
    - LUND R D ET AL, "Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, (20070401), vol. 25, no. 3, ISSN 1066-5099, pages 602 - 611, XP009087718
    - Tiki Bakhshi ET AL, "Mesenchymal stem cells from the Wharton's jelly of umbilical cord segments provide stromal support for the maintenance of cord blood hematopoietic stem cells during long-term ex vivo culture", Transfusion, (20081201), vol. 48, no. 12, doi:10.1111/j.1537-2995.2008.01926.x, ISSN 0041-1132, pages 2638 - 2644, XP055071967

DOI:   http://dx.doi.org/10.1111/j.1537-2995.2008.01926.x
    - Mariane Secco ET AL, "Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!", Stem Cells, (20080101), vol. 26, no. 1, doi:10.1634/stemcells.2007-0381, ISSN 1066-5099, pages 146 - 150, XP055132784

DOI:   http://dx.doi.org/10.1634/stemcells.2007-0381
    - MATUTE-BELLO GUSTAVO ET AL, "Animal models of acute lung injury.", AMERICAN JOURNAL OF PHYSIOLOGY. LUNG CELLULAR AND MOLECULAR PHYSIOLOGY SEP 2008, (200809), vol. 295, no. 3, ISSN 1040-0605, pages L379 - L399
    - RUAN DIKE ET AL, "Differentiation of human Wharton's jelly cells toward nucleus pulposus-like cells after coculture with nucleus pulposus cells in vitro.", TISSUE ENGINEERING. PART A JAN 2012, (201201), vol. 18, no. 1-2, ISSN 1937-335X, pages 167 - 175
    - CAI JINGLI ET AL, "Stem cell and precursor cell therapy.", NEUROMOLECULAR MEDICINE 2002, (2002), vol. 2, no. 3, ISSN 1535-1084, pages 233 - 249
    - N. Gupta ET AL, "Intrapulmonary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Survival and Attenuates Endotoxin-Induced Acute Lung Injury in Mice", THE JOURNAL OF IMMUNOLOGY, US, (20070719), vol. 179, no. 3, doi:10.4049/jimmunol.179.3.1855, ISSN 0022-1767, pages 1855 - 1863, XP055265208

DOI:   http://dx.doi.org/10.4049/jimmunol.179.3.1855
by applicantUS2005032209
 US2005058631
 US2005054098
 US5670483
 US5955343
 US2002160471
 WO02062969
 US6355699
 US2002022676
 US2005058630
 US6555374
 US2004058412
 US2004005704
 WO03025149
    - SPURZEM; RENNARD, SEMIN RESPIR CRIT CARE MED, (2005), vol. 26, pages 142 - 153
    - SIAFAKAS; TZORTZAKI, RESPIR MED, (200208), vol. 96, no. 8, pages 615 - 24
    - MACNEE, PROC AM THORAC SOC., (2005), vol. 2, no. 4, pages 258 - 66
    - GUERASSIMOV, A ET AL., AM J RESPIR CRIT MED, 2004 NOV. 1, (20040728), vol. 170, no. 9, pages 974 - 80
    - YU, B ET AL., INHAL TOXICOL, (200805), vol. 20, no. 7, pages 623 - 33
    - ORTIZ, LA ET AL., PROC NATL ACAD SCI U S A., 2003 JUL. 8, 2003, (20030618), vol. 100, no. 14, pages 8407 - 11
    - ZHAO, F ET AL., TRANSPLANT PROCEEDINGS, (200806), vol. 40, no. 5, pages 1700 - 1705
    - ORTIZ, LA, PROC NATL ACAD SCI USA., (20030708), vol. 100, no. 14, pages 8407 - 11
    - ROJAS ET AL., AM J RESPIR CELL MOL BIOL, (2005), vol. 33, page 145
    - DILLER, G P ET AL., CIRCULATION, (20080610), vol. 117, no. 23, pages 3020 - 30
    - WEISS, D J ET AL., PROC AIN THORAC. SOC., (20080715), vol. 5, no. 5, pages 637 - 67
    - URBICH C; DIMMELER S, CIRC. RES., (2004), vol. 95, pages 343 - 53
    - MOMBAERTS ET AL., PROC. NAT. ACAD. SCI. U.S.A., (1991), vol. 88, pages 3084 - 87
    - TRESCO, P A ET AL., ADV. DRUG DELIVERY REV., (2000), vol. 42, pages 3 - 27
    - HUTMACHER, D W, J BIOMATER. SCI. POLYMER EDN., (2001), vol. 12, pages 107 - 174
    - ANSETH, K S ET AL., J. CONTROLLED RELEASE, (2002), vol. 78, pages 199 - 209
    - WANG, D. ET AL., BIOMATERIALS, (2003), vol. 24, pages 3969 - 3980
    - MARX, WF ET AL., AM. J. NEURORADIOL., (2001), vol. 22, pages 323 - 333
    - HAYFLICK, L, J. AM. GERIATR. SOC., (1974), vol. 22, no. 1, pages 1 - 12
    - HAYFLICK, L, GERONTOLOGIST, (1974), vol. 14, no. 1, pages 37 - 45
    - HONGPAISAN, J, CELL BIOL INT., (2000), vol. 24, pages 1 - 7
    - SORDILLO, L M ET AL., CELL BIOL INT REP., (1988), vol. 12, pages 355 - 64
    - TUSHER, V.G. ET AL., PROC. NATL. ACAD. SCI. USA, (2001), vol. 98, pages 5116 - 5121
    - MESSINA ET AL., EXPER. NEURAL., (2003), vol. 184, pages 816 - 829
    - ROSEN ET AL., CIBA FOUND. SYMP., (1997), vol. 212, pages 215 - 26
    - SALCEDO ET AL., BLOOD, (2000), vol. 96, pages 34 - 40
    - LI ET AL., J. IMMUNOL., (2003), vol. 170, pages 3369 - 76
    - HUGHES ET AL., ANN. THORAC. SURG., (2004), vol. 77, pages 812 - 8
    - CHENG ET AL., DEV. BIOL., (2003), vol. 258, pages 319 - 33
    - ABBAS; LICHTMAN, Cellular and Molecular Immunology, 5th Ed., SAUNDERS, (2003), page 171
    - COUMANS, JOURNAL OF IMMUNOLOGICAL METHODS, (1999), vol. 224, pages 185 - 196
    - BROWN, THE JOURNAL OF IMMUNOLOGY, (2003), vol. 170, pages 1257 - 1266
    - LIU, K ET AL., PNAS, (1999), vol. 96, pages 5147 - 5152
    - PLAIA ET AL., STEM CELLS, (2006), vol. 24, no. 3, pages 531 - 546
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.