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Extract from the Register of European Patents

EP About this file: EP2373299

EP2373299 - A MICROENCAPSULATION PROCESS OF SERTOLI CELLS, MICROCAPSULES OBTAINED AND THEIR USE FOR PREVENTION AND CURE OF TYPE 1 DIABETES MELLITUS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.01.2018
Database last updated on 22.08.2024
FormerThe patent has been granted
Status updated on  17.02.2017
FormerGrant of patent is intended
Status updated on  13.02.2017
Most recent event   Tooltip06.03.2020Lapse of the patent in a contracting state
New state(s): TR		published on 08.04.2020  [2020/15]
Applicant(s)For all designated states
GH CARE INC. d/b/a AltUCell
3 Astor Court
Dix Hills, NY 11746 / US
[2011/44]
Former [2011/41]For all designated states
Universita Degli Studi Di Perugia
Piazza Universita N.1
06100 Perugia / IT
Inventor(s)01 / CALAFIORE, Riccardo
Via della Treggia 8
I-06125 Ponte Rio PG / IT
02 / LUCA, Giovanni
Via della Quercia 1
I-87027 Paola CS / IT
03 / CALVITTI, Mario
Via Cortonese 74A
I-06127 Perugia / IT
04 / BECCHETTI, Ennio
Via Guerriero Guerra 11
I-06127 Perugia / IT
05 / PUCCETTI, Paolo
Via Villaggio S. Livia 1
I-06121 Perugia / IT
06 / FALLARINO, Francesca
Via Ruggero d'Andreotto 12
I-06124 Perugia / IT
07 / NASTRUZZI, Claudio
Via delle Acacie 13
I-44123 Pontegradella FE / IT
 [2011/41]
Representative(s)Feltrinelli, Secondo Andrea
APTA S.r.l. Patent Department Via Ca' di Cozzi, 41
37124 Verona / IT
[2011/41]
Application number, filing date09807677.118.12.2009
[2017/12]
WO2009IB55847
Priority number, dateIT2008RM0068619.12.2008         Original published format: IT RM20080686
[2011/41]
Filing languageIT
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010070618
Date:24.06.2010
Language:EN
[2010/25]
Type: A2 Application without search report 
No.:EP2373299
Date:12.10.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 24.06.2010 takes the place of the publication of the European patent application.
[2011/41]
Type: B1 Patent specification 
No.:EP2373299
Date:22.03.2017
Language:EN
[2017/12]
Search report(s)International search report - published on:EP06.01.2011
ClassificationIPC:A61K9/50, A61K35/48, A61J3/07, A61P3/10
[2016/44]
CPC:
A61K9/5089 (EP,KR,US); A61K9/5036 (EP,KR,US); A61J3/07 (KR,US);
A61K35/48 (EP,KR,US); A61K47/00 (KR); A61P3/10 (EP)
Former IPC [2011/41]A61K9/50, A61K35/48, A61P3/10
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2017/12]
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:MIKROVERKAPSELUNGSVERFAHREN VON SERTOLI-ZELLEN, ERHALTENE MIKROKAPSELN UND IHRE VERWENDUNG ZUR PRÄVENTION UND HEILUNG VON DIABETES MELLITUS TYP 1[2011/45]
English:A MICROENCAPSULATION PROCESS OF SERTOLI CELLS, MICROCAPSULES OBTAINED AND THEIR USE FOR PREVENTION AND CURE OF TYPE 1 DIABETES MELLITUS[2011/41]
French:PROCÉDÉ DE MICRO-ENCAPSULATION DE CELLULES DE SERTOLI, MICROCAPSULES OBTENUES ET LEUR UTILISATION POUR PRÉVENIR ET TRAITER LE DIABÈTE SUCRÉ DE TYPE 1[2011/41]
Former [2011/41]MIKROVERKAPSELUNGSVERFAHREN VON SERTOLI-ZELLEN, ERHALTENE MIKROKAPSELN UND IHRE VERWENDUNG ZUR PR?VENTION UND HEILUNG VON DIABETES MELLITUS TYP 1
Entry into regional phase20.06.2011National basic fee paid 
20.06.2011Designation fee(s) paid 
20.06.2011Examination fee paid 
Examination procedure20.06.2011Examination requested  [2011/41]
29.02.2012Amendment by applicant (claims and/or description)
16.06.2014Despatch of a communication from the examining division (Time limit: M04)
27.10.2014Reply to a communication from the examining division
15.04.2015Despatch of a communication from the examining division (Time limit: M06)
26.10.2015Reply to a communication from the examining division
12.01.2016Despatch of a communication from the examining division (Time limit: M02)
22.03.2016Reply to a communication from the examining division
23.09.2016Cancellation of oral proceeding that was planned for 06.12.2016
10.10.2016Communication of intention to grant the patent
06.12.2016Date of oral proceedings (cancelled)
10.02.2017Fee for grant paid
10.02.2017Fee for publishing/printing paid
10.02.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.06.2014
Opposition(s)02.01.2018No opposition filed within time limit [2018/09]
Fees paidRenewal fee
27.12.2011Renewal fee patent year 03
26.12.2012Renewal fee patent year 04
27.12.2013Renewal fee patent year 05
29.12.2014Renewal fee patent year 06
28.12.2015Renewal fee patent year 07
27.12.2016Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.12.2009
AT22.03.2017
CY22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
MC22.03.2017
MK22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
TR22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
[2020/15]
Former [2019/51]HU18.12.2009
AT22.03.2017
CY22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
MC22.03.2017
MK22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
Former [2019/46]HU18.12.2009
AT22.03.2017
CY22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
MC22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
Former [2019/31]HU18.12.2009
AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
MC22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
Former [2019/30]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
MC22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
Former [2018/52]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
CH31.12.2017
LI31.12.2017
Former [2018/50]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
GB18.12.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
Former [2018/45]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
IE18.12.2017
LU18.12.2017
MT18.12.2017
Former [2018/43]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
LU18.12.2017
MT18.12.2017
Former [2018/14]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SI22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
Former [2018/09]AT22.03.2017
CZ22.03.2017
DK22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
Former [2017/51]AT22.03.2017
CZ22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SK22.03.2017
SM22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
PT24.07.2017
Former [2017/50]AT22.03.2017
CZ22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
PL22.03.2017
RO22.03.2017
SE22.03.2017
SK22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
Former [2017/49]AT22.03.2017
CZ22.03.2017
EE22.03.2017
ES22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
RO22.03.2017
SE22.03.2017
SK22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
IS22.07.2017
Former [2017/48]CZ22.03.2017
FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
SE22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
Former [2017/41]FI22.03.2017
HR22.03.2017
LT22.03.2017
LV22.03.2017
NL22.03.2017
SE22.03.2017
BG22.06.2017
NO22.06.2017
GR23.06.2017
Cited inInternational search[A]US6149907  (SELAWRY HELENA P [US]) [A] 1-13* column 13, line 30 - column 14, line 63 *;
 [XD]  - LUCA G ET AL, "Encapsulation, in vitro characterization, and in vivo biocompatibility of Sertoli cells in alginate-based microcapsules", TISSUE ENGINEERING, LARCHMONT, NY, US LNKD- DOI:10.1089/TEN.2006.0137, (20070101), vol. 13, no. 3, ISSN 1076-3279, pages 641 - 648, XP002540887 [XD] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1089/ten.2006.0137
 [A]  - DE VOS P ET AL, "Upscaling the production of microencapsulated pancreatic islets", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB LNKD- DOI:10.1016/S0142-9612(97)00040-9, (19970801), vol. 18, no. 16, ISSN 0142-9612, pages 1085 - 1090, XP004083116 [A] 10-13 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0142-9612(97)00040-9
 [A]  - LUCA G ET AL, "Le cellule del Sertoli migliorano la funzionalita delle insule pancreatiche di ratto adulto: potenziali applicazioni nella cura radicale del diabete mellito di tipo I previa co-microincapsulazione in microcapsule di alginato/poli-L-ornitina", ACTA TECNOLOGIAE ET LEGIS MEDICAMENTI, CASA EDITRICE MACCARI, IT, (20020101), vol. 13, no. 1, ISSN 1121-2098, pages 61 - 71, XP008109560 [A] 1-13 * the whole document *
 [A]  - LUCA G ET AL, "Improved function of rat islets upon co-microencapsulation with Sertoli's cells in alginate/poly-L-ornithine", AAPS PHARMSCITECH, SPRINGER NEW YORK LLC, US LNKD- DOI:10.1208/PT020315, (20010826), vol. 2, no. 3, ISSN 1530-9932, pages 15 - 1, XP008109566 [A] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1208/pt020315
Examination   - S MAZZITELLI ET AL, "Multicompartimental microcapsules for cell entrapment", XVITH INTERNATIONAL CONFERENCE ON BIOENCAPSULATION, (20080906), pages P55-1 - P55-4, URL: http://impascience.eu/bioencapsulation/340_contribution_texts/2008-09-04_P55.pdf, (20140602), XP055120972
    - WALSH THOMAS ET AL, "Expression of insulin by sertoli cells reverses diabetes in scid mice", JOURNAL OF ANDROLOGY, & 33RD ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-ANDROLOGY; ALBUQUERQUE, NM, USA; APRIL 12 -15, 2008, (200803), no. Suppl. S, ISSN 0196-3635, page 44, XP008169715
    - C.G. THANOS ET AL, "Formulating the alginate-polyornithine biocapsule for prolonged stability: Evaluation of composition and manufacturing technique", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, (20070101), vol. 83A, no. 1, doi:10.1002/jbm.a.31472, ISSN 1549-3296, pages 216 - 224, XP055120966

DOI:   http://dx.doi.org/10.1002/jbm.a.31472
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