EP2373299 - A MICROENCAPSULATION PROCESS OF SERTOLI CELLS, MICROCAPSULES OBTAINED AND THEIR USE FOR PREVENTION AND CURE OF TYPE 1 DIABETES MELLITUS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 26.01.2018 Database last updated on 22.08.2024 | |
Former | The patent has been granted Status updated on 17.02.2017 | ||
Former | Grant of patent is intended Status updated on 13.02.2017 | Most recent event Tooltip | 06.03.2020 | Lapse of the patent in a contracting state New state(s): TR | published on 08.04.2020 [2020/15] | Applicant(s) | For all designated states GH CARE INC. d/b/a AltUCell 3 Astor Court Dix Hills, NY 11746 / US | [2011/44] |
Former [2011/41] | For all designated states Universita Degli Studi Di Perugia Piazza Universita N.1 06100 Perugia / IT | Inventor(s) | 01 /
CALAFIORE, Riccardo Via della Treggia 8 I-06125 Ponte Rio PG / IT | 02 /
LUCA, Giovanni Via della Quercia 1 I-87027 Paola CS / IT | 03 /
CALVITTI, Mario Via Cortonese 74A I-06127 Perugia / IT | 04 /
BECCHETTI, Ennio Via Guerriero Guerra 11 I-06127 Perugia / IT | 05 /
PUCCETTI, Paolo Via Villaggio S. Livia 1 I-06121 Perugia / IT | 06 /
FALLARINO, Francesca Via Ruggero d'Andreotto 12 I-06124 Perugia / IT | 07 /
NASTRUZZI, Claudio Via delle Acacie 13 I-44123 Pontegradella FE / IT | [2011/41] | Representative(s) | Feltrinelli, Secondo Andrea APTA S.r.l. Patent Department Via Ca' di Cozzi, 41 37124 Verona / IT | [2011/41] | Application number, filing date | 09807677.1 | 18.12.2009 | [2017/12] | WO2009IB55847 | Priority number, date | IT2008RM00686 | 19.12.2008 Original published format: IT RM20080686 | [2011/41] | Filing language | IT | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2010070618 | Date: | 24.06.2010 | Language: | EN | [2010/25] | Type: | A2 Application without search report | No.: | EP2373299 | Date: | 12.10.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 24.06.2010 takes the place of the publication of the European patent application. | [2011/41] | Type: | B1 Patent specification | No.: | EP2373299 | Date: | 22.03.2017 | Language: | EN | [2017/12] | Search report(s) | International search report - published on: | EP | 06.01.2011 | Classification | IPC: | A61K9/50, A61K35/48, A61J3/07, A61P3/10 | [2016/44] | CPC: |
A61K9/5089 (EP,KR,US);
A61K9/5036 (EP,KR,US);
A61J3/07 (KR,US);
A61K35/48 (EP,KR,US);
A61K47/00 (KR);
A61P3/10 (EP)
|
Former IPC [2011/41] | A61K9/50, A61K35/48, A61P3/10 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2017/12] | Extension states | AL | Not yet paid | BA | Not yet paid | RS | Not yet paid | Title | German: | MIKROVERKAPSELUNGSVERFAHREN VON SERTOLI-ZELLEN, ERHALTENE MIKROKAPSELN UND IHRE VERWENDUNG ZUR PRÄVENTION UND HEILUNG VON DIABETES MELLITUS TYP 1 | [2011/45] | English: | A MICROENCAPSULATION PROCESS OF SERTOLI CELLS, MICROCAPSULES OBTAINED AND THEIR USE FOR PREVENTION AND CURE OF TYPE 1 DIABETES MELLITUS | [2011/41] | French: | PROCÉDÉ DE MICRO-ENCAPSULATION DE CELLULES DE SERTOLI, MICROCAPSULES OBTENUES ET LEUR UTILISATION POUR PRÉVENIR ET TRAITER LE DIABÈTE SUCRÉ DE TYPE 1 | [2011/41] |
Former [2011/41] | MIKROVERKAPSELUNGSVERFAHREN VON SERTOLI-ZELLEN, ERHALTENE MIKROKAPSELN UND IHRE VERWENDUNG ZUR PR?VENTION UND HEILUNG VON DIABETES MELLITUS TYP 1 | Entry into regional phase | 20.06.2011 | National basic fee paid | 20.06.2011 | Designation fee(s) paid | 20.06.2011 | Examination fee paid | Examination procedure | 20.06.2011 | Examination requested [2011/41] | 29.02.2012 | Amendment by applicant (claims and/or description) | 16.06.2014 | Despatch of a communication from the examining division (Time limit: M04) | 27.10.2014 | Reply to a communication from the examining division | 15.04.2015 | Despatch of a communication from the examining division (Time limit: M06) | 26.10.2015 | Reply to a communication from the examining division | 12.01.2016 | Despatch of a communication from the examining division (Time limit: M02) | 22.03.2016 | Reply to a communication from the examining division | 23.09.2016 | Cancellation of oral proceeding that was planned for 06.12.2016 | 10.10.2016 | Communication of intention to grant the patent | 06.12.2016 | Date of oral proceedings (cancelled) | 10.02.2017 | Fee for grant paid | 10.02.2017 | Fee for publishing/printing paid | 10.02.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 16.06.2014 | Opposition(s) | 02.01.2018 | No opposition filed within time limit [2018/09] | Fees paid | Renewal fee | 27.12.2011 | Renewal fee patent year 03 | 26.12.2012 | Renewal fee patent year 04 | 27.12.2013 | Renewal fee patent year 05 | 29.12.2014 | Renewal fee patent year 06 | 28.12.2015 | Renewal fee patent year 07 | 27.12.2016 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 18.12.2009 | AT | 22.03.2017 | CY | 22.03.2017 | CZ | 22.03.2017 | DK | 22.03.2017 | EE | 22.03.2017 | ES | 22.03.2017 | FI | 22.03.2017 | HR | 22.03.2017 | LT | 22.03.2017 | LV | 22.03.2017 | MC | 22.03.2017 | MK | 22.03.2017 | NL | 22.03.2017 | PL | 22.03.2017 | RO | 22.03.2017 | SE | 22.03.2017 | SI | 22.03.2017 | SK | 22.03.2017 | SM | 22.03.2017 | TR | 22.03.2017 | BG | 22.06.2017 | NO | 22.06.2017 | GR | 23.06.2017 | IS | 22.07.2017 | PT | 24.07.2017 | GB | 18.12.2017 | IE | 18.12.2017 | LU | 18.12.2017 | MT | 18.12.2017 | CH | 31.12.2017 | LI | 31.12.2017 | [2020/15] |
Former [2019/51] | HU | 18.12.2009 | |
AT | 22.03.2017 | ||
CY | 22.03.2017 | ||
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
MC | 22.03.2017 | ||
MK | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
CH | 31.12.2017 | ||
LI | 31.12.2017 | ||
Former [2019/46] | HU | 18.12.2009 | |
AT | 22.03.2017 | ||
CY | 22.03.2017 | ||
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
MC | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
CH | 31.12.2017 | ||
LI | 31.12.2017 | ||
Former [2019/31] | HU | 18.12.2009 | |
AT | 22.03.2017 | ||
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
MC | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
CH | 31.12.2017 | ||
LI | 31.12.2017 | ||
Former [2019/30] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
MC | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
CH | 31.12.2017 | ||
LI | 31.12.2017 | ||
Former [2018/52] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
CH | 31.12.2017 | ||
LI | 31.12.2017 | ||
Former [2018/50] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
GB | 18.12.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
Former [2018/45] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
IE | 18.12.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
Former [2018/43] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
LU | 18.12.2017 | ||
MT | 18.12.2017 | ||
Former [2018/14] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SI | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
Former [2018/09] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
DK | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
Former [2017/51] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SK | 22.03.2017 | ||
SM | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
PT | 24.07.2017 | ||
Former [2017/50] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
PL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SK | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
Former [2017/49] | AT | 22.03.2017 | |
CZ | 22.03.2017 | ||
EE | 22.03.2017 | ||
ES | 22.03.2017 | ||
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
RO | 22.03.2017 | ||
SE | 22.03.2017 | ||
SK | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
IS | 22.07.2017 | ||
Former [2017/48] | CZ | 22.03.2017 | |
FI | 22.03.2017 | ||
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
SE | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | ||
Former [2017/41] | FI | 22.03.2017 | |
HR | 22.03.2017 | ||
LT | 22.03.2017 | ||
LV | 22.03.2017 | ||
NL | 22.03.2017 | ||
SE | 22.03.2017 | ||
BG | 22.06.2017 | ||
NO | 22.06.2017 | ||
GR | 23.06.2017 | Cited in | International search | [A]US6149907 (SELAWRY HELENA P [US]) [A] 1-13* column 13, line 30 - column 14, line 63 *; | [XD] - LUCA G ET AL, "Encapsulation, in vitro characterization, and in vivo biocompatibility of Sertoli cells in alginate-based microcapsules", TISSUE ENGINEERING, LARCHMONT, NY, US LNKD- DOI:10.1089/TEN.2006.0137, (20070101), vol. 13, no. 3, ISSN 1076-3279, pages 641 - 648, XP002540887 [XD] 1-13 * the whole document * DOI: http://dx.doi.org/10.1089/ten.2006.0137 | [A] - DE VOS P ET AL, "Upscaling the production of microencapsulated pancreatic islets", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB LNKD- DOI:10.1016/S0142-9612(97)00040-9, (19970801), vol. 18, no. 16, ISSN 0142-9612, pages 1085 - 1090, XP004083116 [A] 10-13 * the whole document * DOI: http://dx.doi.org/10.1016/S0142-9612(97)00040-9 | [A] - LUCA G ET AL, "Le cellule del Sertoli migliorano la funzionalita delle insule pancreatiche di ratto adulto: potenziali applicazioni nella cura radicale del diabete mellito di tipo I previa co-microincapsulazione in microcapsule di alginato/poli-L-ornitina", ACTA TECNOLOGIAE ET LEGIS MEDICAMENTI, CASA EDITRICE MACCARI, IT, (20020101), vol. 13, no. 1, ISSN 1121-2098, pages 61 - 71, XP008109560 [A] 1-13 * the whole document * | [A] - LUCA G ET AL, "Improved function of rat islets upon co-microencapsulation with Sertoli's cells in alginate/poly-L-ornithine", AAPS PHARMSCITECH, SPRINGER NEW YORK LLC, US LNKD- DOI:10.1208/PT020315, (20010826), vol. 2, no. 3, ISSN 1530-9932, pages 15 - 1, XP008109566 [A] 1-13 * the whole document * DOI: http://dx.doi.org/10.1208/pt020315 | Examination | - S MAZZITELLI ET AL, "Multicompartimental microcapsules for cell entrapment", XVITH INTERNATIONAL CONFERENCE ON BIOENCAPSULATION, (20080906), pages P55-1 - P55-4, URL: http://impascience.eu/bioencapsulation/340_contribution_texts/2008-09-04_P55.pdf, (20140602), XP055120972 | - WALSH THOMAS ET AL, "Expression of insulin by sertoli cells reverses diabetes in scid mice", JOURNAL OF ANDROLOGY, & 33RD ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-ANDROLOGY; ALBUQUERQUE, NM, USA; APRIL 12 -15, 2008, (200803), no. Suppl. S, ISSN 0196-3635, page 44, XP008169715 | - C.G. THANOS ET AL, "Formulating the alginate-polyornithine biocapsule for prolonged stability: Evaluation of composition and manufacturing technique", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, (20070101), vol. 83A, no. 1, doi:10.1002/jbm.a.31472, ISSN 1549-3296, pages 216 - 224, XP055120966 DOI: http://dx.doi.org/10.1002/jbm.a.31472 |