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Extract from the Register of European Patents

EP About this file: EP2340258

EP2340258 - METHODS FOR SYNTHESIS AND USES OF INHIBITORS OF GHRELIN O-ACYLTRANSFERASE AS POTENTIAL THERAPEUTIC AGENTS FOR OBESITY AND DIABETES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  01.08.2014
Database last updated on 15.07.2024
Most recent event   Tooltip01.08.2014Application deemed to be withdrawnpublished on 03.09.2014  [2014/36]
Applicant(s)For all designated states
The Johns Hopkins University
3400 North Charles Street
Baltimore, MD 21218 / US
[2011/27]
Inventor(s)01 / COLE, Philip A.
725 North Wolfe Street
Baltimore Maryland 21205 / US
02 / BARNETT, Bradley P.
725 North Wolfe Street
Baltimore Maryland 21205 / US
03 / HWANG, Yousang
725 North Wolfe Street
Baltimore Maryland 21205 / US
04 / BOEKE, Jef D.
733 North Broadway
Baltimore Maryland 21205 / US
 [2011/27]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[N/P]
Former [2012/09]von Kreisler Selting Werner
Patentanwälte
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
Former [2011/27]von Kreisler, Alek
Von Kreisler Selting Werner Deichmannhaus am Dom Bahnhofsvorplatz 1
50667 Köln / DE
Application number, filing date09818229.818.09.2009
[2011/27]
WO2009US57512
Priority number, dateUS20080102549P03.10.2008         Original published format: US 102549 P
[2011/27]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010039461
Date:08.04.2010
Language:EN
[2010/14]
Type: A2 Application without search report 
No.:EP2340258
Date:06.07.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 08.04.2010 takes the place of the publication of the European patent application.
[2011/27]
Search report(s)International search report - published on:KR01.07.2010
(Supplementary) European search report - dispatched on:EP21.01.2013
ClassificationIPC:C07K7/00, A61K38/08, A61K38/10, A61P3/10, A61K47/48
[2013/08]
CPC:
C07K14/60 (EP,US); A61K47/645 (EP,US); A61P1/00 (EP);
A61P3/04 (EP); A61P3/10 (EP); A61P7/12 (EP);
A61K38/00 (EP,US) (-)
Former IPC [2011/27]C07K7/00, A61K38/08, A61K38/10, A61P3/10
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/27]
TitleGerman:VERFAHREN ZUR SYNTHESE UND ANWENDUNGEN VON INHIBITOREN VON GHRELIN-O-ACYLTRANSFERASE ALS POTENTIELLE THERAPEUTISCHE MITTEL GEGEN OBESITAS UND DIABETES[2011/27]
English:METHODS FOR SYNTHESIS AND USES OF INHIBITORS OF GHRELIN O-ACYLTRANSFERASE AS POTENTIAL THERAPEUTIC AGENTS FOR OBESITY AND DIABETES[2011/27]
French:PROCÉDÉS DE SYNTHÈSE ET D'UTILISATION D'INHIBITEURS DE LA GRHÉLINE O-ACYLTRANSFÉRASE COMME AGENTS THÉRAPEUTIQUES POTENTIELS POUR TRAITER L'OBÉSITÉ ET LE DIABÈTE[2011/27]
Entry into regional phase21.04.2011National basic fee paid 
21.04.2011Search fee paid 
21.04.2011Designation fee(s) paid 
21.04.2011Examination fee paid 
Examination procedure21.04.2011Examination requested  [2011/27]
16.08.2013Amendment by applicant (claims and/or description)
01.04.2014Application deemed to be withdrawn, date of legal effect  [2014/36]
29.04.2014Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2014/36]
Fees paidRenewal fee
25.10.2011Renewal fee patent year 03
25.09.2012Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
30.09.201103   M06   Fee paid on   25.10.2011
30.09.201305   M06   Not yet paid
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Documents cited:Search[I]WO2007041278  (SOD CONSEILS RECH APPLIC [FR], et al) [I] 1-14 * the whole document *;
 [I]  - JING YANG ET AL, "Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 105, no. 31, doi:10.1073/PNAS.0805353105, ISSN 0027-8424, (20080805), pages 10750 - 10755, (20080731), XP008145947 [I] 1-14 * the whole document * * page 10753; figure 8 *

DOI:   http://dx.doi.org/10.1073/pnas.0805353105
 [T]  - B. P. BARNETT ET AL, "Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor", SCIENCE, (20101217), vol. 330, no. 6011, doi:10.1126/science.1196154, ISSN 0036-8075, pages 1689 - 1692, XP055048732

DOI:   http://dx.doi.org/10.1126/science.1196154
International search[T]US2010086955  (HARRAN PATRCIK G [US], et al);
 [A]  - MASAYASU KOJIMA ET AL., "Ghrelin: Structure and Function", PHYSIOLGICAL REVIEWS, (2005), vol. 85, pages 495 - 522, XP002453764

DOI:   http://dx.doi.org/10.1152/physrev.00012.2004
 [A]  - JING YANG ET AL., "Inhibition of ghrelin 0-acyltransferase (GOAT) by octanoylated pentapeptides", PNAS, (20080805), vol. 105, no. 31, pages 10750 - 10755, XP008145947

DOI:   http://dx.doi.org/10.1073/pnas.0805353105
 [A]  - ORESTEN GUALILLO ET AL., "Introducing GOAT: a target for obesity and anti- diabetic drugs?", TRENDS IN PHARMACOLOGICAL SCIENCES, (20080706), vol. 29, no. 8, pages 398 - 401, XP027070052

DOI:   http://dx.doi.org/10.1016/j.tips.2008.06.003
 [A]  - COMMERCIAL CATALOG OF PHOENIX PHARMACEUTICALS, INC., (2010), URL: http://www.phoenixpeptide.com/catalog/pnxfoget.php?id=pnxnews_000000635&title=Compound&sum=Function, XP008145948
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.