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Extract from the Register of European Patents

EP About this file: EP2351851

EP2351851 - METHOD FOR MEASURING CYTOKERATIN-19 MRNA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.05.2016
Database last updated on 03.10.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
Tosoh Corporation
4560, Kaisei-cho Shunan-shi
Yamaguchi 746-8501 / JP
[2011/31]
Inventor(s)01 / OMOTO, Daisuke
c/o TOSOH CORPORATION
Tokyo Research Center
2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
02 / SAITO, Juichi
c/o TOSOH CORPORATION
Tokyo Research Center
2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
03 / OONAKA, Satoru
c/o TOSOH CORPORATION
Tokyo Research Center
2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
04 / HAYASHI, Toshinori
c/o TOSOH CORPORATION
Tokyo Research Center
2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
 [2015/28]
Former [2011/31]01 / OMOTO, Daisuke
c/o TOSOH CORPORATION Tokyo Research Center 2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
02 / SAITO, Juichi
c/o TOSOH CORPORATION Tokyo Research Center 2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
03 / OONAKA, Satoru
c/o TOSOH CORPORATION Tokyo Research Center 2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
04 / HAYASHI, Toshinori
c/o TOSOH CORPORATION Tokyo Research Center 2743-1 Hayakawa
Ayase-shi Kanagawa 252-1123 / JP
Representative(s)Vigand, Philippe, et al
Novagraaf International SA
Chemin de l'Echo 3
1213 Onex - Genève / CH
[N/P]
Former [2015/28]Kügele, Bernhard, et al
Novagraaf International SA
Chemin de l'Echo 3
1213 Onex / CH
Former [2011/31]Kügele, Bernhard, et al
Novagraaf International SA Chemin de l'Echo 3
1213 Onex / CH
Former [2011/31]Kügele, Bernhard, et al
Novagraaf International SA 25, avenue du Pailly
CH-1220 Les Avanchets-Genève / CH
Application number, filing date09829212.130.11.2009
[2011/31]
WO2009JP70439
Priority number, dateJP2008030363728.11.2008         Original published format: JP 2008303637
[2011/31]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010061981
Date:03.06.2010
Language:JA
[2010/22]
Type: A1 Application with search report 
No.:EP2351851
Date:03.08.2011
Language:EN
[2011/31]
Type: B1 Patent specification 
No.:EP2351851
Date:08.07.2015
Language:EN
[2015/28]
Search report(s)International search report - published on:JP03.06.2010
(Supplementary) European search report - dispatched on:EP28.09.2011
ClassificationIPC:C12Q1/68, C12N15/09
[2011/31]
CPC:
C12Q1/6853 (EP,US); C12Q1/6865 (EP,US)
C-Set:
C12Q1/6853, C12Q2525/143, C12Q2545/114, C12Q2561/113 (EP,US);
C12Q1/6865, C12Q2531/143, C12Q2525/143, C12Q2521/107, C12Q1/6865, C12Q2545/114, C12Q2561/113 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2015/28]
Former [2011/31]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
Extension statesALNot yet paid
BANot yet paid
RSNot yet paid
TitleGerman:VERFAHREN ZUR CYTOKERATIN-19-MRNA-MESSUNG[2011/31]
English:METHOD FOR MEASURING CYTOKERATIN-19 MRNA[2011/31]
French:PROCÉDÉ POUR MESURER L'ARNM DE CYTOKÉRATINE-19[2011/31]
Entry into regional phase20.05.2011Translation filed 
20.05.2011National basic fee paid 
20.05.2011Search fee paid 
20.05.2011Designation fee(s) paid 
20.05.2011Examination fee paid 
Examination procedure20.05.2011Examination requested  [2011/31]
03.08.2012Amendment by applicant (claims and/or description)
29.10.2012Despatch of a communication from the examining division (Time limit: M04)
26.02.2013Reply to a communication from the examining division
05.11.2013Despatch of a communication from the examining division (Time limit: M04)
11.03.2014Reply to a communication from the examining division
04.12.2014Communication of intention to grant the patent
30.01.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
24.02.2015Communication of intention to grant the patent
27.05.2015Fee for grant paid
27.05.2015Fee for publishing/printing paid
27.05.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  29.10.2012
Opposition(s)11.04.2016No opposition filed within time limit [2016/24]
Fees paidRenewal fee
22.11.2011Renewal fee patent year 03
19.11.2012Renewal fee patent year 04
15.10.2013Renewal fee patent year 05
29.09.2014Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.11.2009
AT08.07.2015
BE08.07.2015
BG08.07.2015
CY08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
MK08.07.2015
MT08.07.2015
NL08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
SM08.07.2015
TR08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
IE30.11.2015
LI30.11.2015
LU30.11.2015
[2018/30]
Former [2017/38]HU30.11.2009
AT08.07.2015
BE08.07.2015
BG08.07.2015
CY08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
MT08.07.2015
NL08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
SM08.07.2015
TR08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
IE30.11.2015
LI30.11.2015
LU30.11.2015
Former [2017/03]AT08.07.2015
BE08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
IE30.11.2015
LI30.11.2015
LU30.11.2015
Former [2016/45]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
IE30.11.2015
LI30.11.2015
LU30.11.2015
Former [2016/36]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
LI30.11.2015
LU30.11.2015
Former [2016/34]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
CH30.11.2015
LI30.11.2015
LU30.11.2015
Former [2016/31]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
LU30.11.2015
Former [2016/28]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
MC08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/23]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
PL08.07.2015
RO08.07.2015
SE08.07.2015
SK08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/22]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
PL08.07.2015
SE08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/20]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
PL08.07.2015
SE08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/11]AT08.07.2015
ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
PL08.07.2015
SE08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/10]ES08.07.2015
FI08.07.2015
HR08.07.2015
LT08.07.2015
LV08.07.2015
PL08.07.2015
SE08.07.2015
NO08.10.2015
GR09.10.2015
IS08.11.2015
PT09.11.2015
Former [2016/09]FI08.07.2015
LT08.07.2015
LV08.07.2015
NO08.10.2015
GR09.10.2015
Former [2016/08]LT08.07.2015
NO08.10.2015
Former [2016/07]LT08.07.2015
Documents cited:Search[Y]EP1475445  (TOSOH CORP [JP]) [Y] 1-9 * the whole document *;
 [Y]EP1783232  (TOSOH CORP [JP]) [Y] 1-9 * the whole document *;
 [Y]EP1780289  (TOSOH CORP [JP]) [Y] 1-9 * the whole document *;
 [Y]EP0855447  (TOSOH CORP [JP]) [Y] 1-9 * the whole document *;
 [Y]WO9617079  (AKZO NOBEL NV [NL], et al) [Y] 1-9 * the whole document *;
 [X]WO0173031  (CORIXA CORP [US], et al) [X] 8,9 * sequence 29 *;
 [X]US6504010  (WANG TONGTONG [US], et al) [X] 8,9 * sequence 1377 *;
 [Y]  - Premierbiosoft, "NASBA Technology", (19940101), URL: http://www.premierbiosoft.com/tech_notes/NASBA.html, (20110817), XP055004958 [Y] 1-9 * the whole document *
 [Y]  - KIEVITS T ET AL, "NASBA TM ISOTHERMAL ENZYMATIC IN VITRO NUCLEIC ACID AMPLIFICATION OPTIMIZED FOR THE DIAGNOSIS OF HIV-1 INFECTION", JOURNAL OF VIROLOGICAL METHODS, ELSEVIER BV, NL, (19911201), vol. 35, no. 3, doi:10.1016/0166-0934(91)90069-C, ISSN 0166-0934, pages 273 - 286, XP000576430 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/0166-0934(91)90069-C
 [Y]  - ISHIGURO T ET AL, "INTERCALATION ACTIVATING FLUORESCENCE DNA PROBE AND ITS APPLICATION TO HOMOGENEOUS QUANTIFICATION OF A TARGET SEQUENCE BY ISOTHERMAL SEQUENCE AMPLIFICATION IN A CLOSED VESSEL", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, (20030101), vol. 314, doi:10.1016/S0003-2697(02)00618-8, ISSN 0003-2697, pages 77 - 86, XP001165733 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0003-2697(02)00618-8
 [Y]  - LAMBRECHTS A C ET AL, "COMPARISON OF IMMUNOCYTOCHEMISTRY, REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION, AND NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION FOR THE DETECTION OF CIRCULATING BREAST CANCER CELLS", BREAST CANCER RESEARCH AND TREATMENT, SPRINGER, NEW YORK, NY, (19990801), vol. 56, no. 3, doi:10.1023/A:1006261731125, ISSN 0167-6806, pages 219 - 231, XP009035704 [Y] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.1023/A:1006261731125
International search[Y]JP2007275016  (HOFFMANN LA ROCHE, et al);
 [Y]JP2008194028  (SYSMEX CORP);
 [Y]JP2000014400  (TOSOH CORP);
 [Y]JP2003033182  (TOSOH CORP);
 [Y]JP2003289869  (TOSOH CORP);
 [Y]JP2001333783  (TOSOH CORP);
 [Y]JP2002320481  (TOSOH CORP);
 [Y]JP2008000112  (SYSMEX CORP);
 [X]WO03026584  (GEN HOSPITAL CORP [US], et al);
 [Y]  - ISHIGURO, T. ET AL., "Intercalation activating fluorescence DNA probe and its application to homogeneous quantification of a target sequence by isothermal sequence amplification in a closed vessel.", ANALYTICAL BIOCHEMISTRY, (2003), vol. 314, pages 77 - 86, XP001165733

DOI:   http://dx.doi.org/10.1016/S0003-2697(02)00618-8
 [YP]  - OMOTO, D. ET AL., "TRC-ho ni yoru Nyugan Sentinel Lymph-setsu Ten'i no Shindan no Yuyosei", THE JAPAN SOCIETY FOR CLINICAL LABORATORY AUTOMATION DAI 41 KAI TAIKAI SHOROKUSHU, (20090901), page 578, XP008147159
 [YP]  - OMOTO, D. ET AL., "Nyugan Sentinel Lymph-setsu Seiken ni Okeru TRC CK19 mRNA Sokutei no Yuyosei", DAI 56 KAI JAPANESE SOCIETY OF LABORATORY MEDICINE GAKUJUTSU SHUKAI, (20090728), page 296, XP008148249
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.