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Extract from the Register of European Patents

EP About this file: EP2210612

EP2210612 - Macrocyclic antagonists of the motilin receptor [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.08.2017
Database last updated on 31.08.2024
Most recent event   Tooltip06.03.2020Lapse of the patent in a contracting state
New state(s): TR		published on 08.04.2020  [2020/15]
Applicant(s)For all designated states
Ocera Therapeutics, Inc.
525 University Avenue, Suite 610
Palo Alto, CA 94301 / US
[2015/24]
Former [2010/30]For all designated states
Tranzyme Pharma Inc.
3001 12e avenue Nord IPS Sherbrooke
Quebec J1H 5N4 / CA
Inventor(s)01 / Marsault, Eric
540 Meilleur
Sherbrooke, Québec J1J 2P6 / CA
02 / Benakli, Kamel
10736 Saint Denis
Montreal, Québec H3L 2J5 / CA
03 / Peterson, Mark
3588 rue Alfred-Desrochers
Rock Forest, Québec J1N 2X1 / CA
04 / Beaubien, Sylvie
4070 Rouleau
Sherbrooke, Québec J1L 1L5 / CA
05 / St-Louis, Carl
2355 Rue des Sapins
Sherbrooke, Québec J1R 0G5 / CA
06 / Ouellet, Luc
1191 Aubry
Sherbrooke, Québec J1G 2Z4 / CA
07 / Beauchemin, Sophie
3695 La Verendrye
Sherbrooke, Québec J1L 1W6 / CA
08 / Hoveyda, Hamid
615 Victoria Street, No. 3
Sherbrooke Québec J1H 3J4 / CA
 [2010/30]
Representative(s)McNab, Donald C.
Marks & Clerk LLP The Beacon
176 St Vincent Street
Glasgow G2 5SG / GB
[N/P]
Former [2016/40]McNab, Donald C.
Marks & Clerk LLP
Aurora
120 Bothwell Street
Glasgow
G2 7JS / GB
Former [2010/30]McNab, Donald C.
Marks & Clerk LLP Aurora 120 Bothwell Street Glasgow
G2 7JS / GB
Application number, filing date10001568.418.06.2004
[2010/30]
Priority number, dateUS20030479223P18.06.2003         Original published format: US 479223 P
[2010/30]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2210612
Date:28.07.2010
Language:EN
[2010/30]
Type: A3 Search report 
No.:EP2210612
Date:24.11.2010
[2010/47]
Type: B1 Patent specification 
No.:EP2210612
Date:05.10.2016
Language:EN
[2016/40]
Search report(s)(Supplementary) European search report - dispatched on:EP22.10.2010
ClassificationIPC:A61K38/22, C07K5/08, C07C13/00, C07C15/00, C07D213/00
[2010/30]
CPC:
A61K38/12 (EP,US); C07C213/08 (US); A61K38/2214 (EP,US);
A61P1/00 (EP); A61P1/04 (EP); A61P1/12 (EP);
A61P1/18 (EP); A61P25/00 (EP); A61P3/04 (EP);
A61P3/10 (EP); A61P43/00 (EP); C07C41/18 (US);
C07C67/343 (US); C07D273/00 (EP,US); C07D413/06 (EP,US);
C07D498/04 (EP,US); C07K5/0812 (EP,US); C07K5/0821 (EP,US);
C07K5/0827 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/40]
Former [2010/30]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Makrozyklische Motilin Rezeptorantagonisten[2010/49]
English:Macrocyclic antagonists of the motilin receptor[2010/30]
French:Antagonistes macrocycliques du récepteur de motiline[2010/49]
Former [2010/30]Makrozyklische Motilin Rezeptorantagonisten
Former [2010/30]Antagonistes macrocycliques du récépteur de motiline
Examination procedure17.05.2011Examination requested  [2011/26]
20.05.2011Amendment by applicant (claims and/or description)
15.12.2011Despatch of a communication from the examining division (Time limit: M06)
06.06.2012Reply to a communication from the examining division
12.08.2013Despatch of a communication from the examining division (Time limit: M08)
15.04.2014Reply to a communication from the examining division
13.06.2014Despatch of a communication from the examining division (Time limit: M06)
20.01.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
30.03.2015Reply to a communication from the examining division
19.04.2016Communication of intention to grant the patent
26.08.2016Fee for grant paid
26.08.2016Fee for publishing/printing paid
26.08.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP04737852.6  / EP1633774
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20040737852) is  28.04.2006
Opposition(s)06.07.2017No opposition filed within time limit [2017/37]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
30.03.2015Request for further processing filed
30.03.2015Full payment received (date of receipt of payment)
Request granted
09.04.2015Decision despatched
Fees paidRenewal fee
16.02.2010Renewal fee patent year 03
16.02.2010Renewal fee patent year 04
16.02.2010Renewal fee patent year 05
16.02.2010Renewal fee patent year 06
25.06.2010Renewal fee patent year 07
27.06.2011Renewal fee patent year 08
26.06.2012Renewal fee patent year 09
27.06.2013Renewal fee patent year 10
27.10.2014Renewal fee patent year 11
29.06.2015Renewal fee patent year 12
27.06.2016Renewal fee patent year 13
Penalty fee
Additional fee for renewal fee
30.06.201411   M06   Fee paid on   27.10.2014
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.06.2004
AT05.10.2016
BE05.10.2016
CY05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
TR05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
LU18.06.2017
CH30.06.2017
FR30.06.2017
LI30.06.2017
[2020/15]
Former [2019/46]HU18.06.2004
AT05.10.2016
BE05.10.2016
CY05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
LU18.06.2017
CH30.06.2017
FR30.06.2017
LI30.06.2017
Former [2019/31]HU18.06.2004
AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
LU18.06.2017
CH30.06.2017
FR30.06.2017
LI30.06.2017
Former [2018/29]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
LU18.06.2017
CH30.06.2017
FR30.06.2017
LI30.06.2017
Former [2018/21]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
LU18.06.2017
CH30.06.2017
LI30.06.2017
Former [2018/11]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
MC05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
Former [2017/52]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SI05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
Former [2017/38]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SK05.10.2016
BG05.01.2017
GR06.01.2017
PT06.02.2017
Former [2017/36]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
SK05.10.2016
GR06.01.2017
PT06.02.2017
Former [2017/35]AT05.10.2016
BE05.10.2016
CZ05.10.2016
DK05.10.2016
EE05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
RO05.10.2016
SE05.10.2016
GR06.01.2017
PT06.02.2017
Former [2017/33]AT05.10.2016
BE05.10.2016
DK05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
SE05.10.2016
GR06.01.2017
PT06.02.2017
Former [2017/29]AT05.10.2016
BE05.10.2016
ES05.10.2016
FI05.10.2016
NL05.10.2016
PL05.10.2016
SE05.10.2016
GR06.01.2017
PT06.02.2017
Documents cited:Search[X]EP0818431  (LILLY CO ELI [US]) [X] 1* 2-[[2-[[(phenylmethyl)amino]methyl]phenyl]thio]-Benzenemethanol (RN 202198-90-1).; page 24, line 57 - line 58 *;
 [X]WO0125257  (NEOKIMIA INC [CA]) [X] 1,2,11-15 * T8; page 34, line 15 * * T2; page 39, line 25 *;
 [A]  - HALAB LILIANE ET AL, "Design, synthesis, and conformational analysis of azacycloalkane amino acids as conformationally constrained probes for mimicry of peptide secondary structures", BIOPOLYMERS, NEW YORK, NY, US LNKD- DOI:10.1002/1097-0282(2000)55:2<101::AID-BIP20>3.0.CO;2-O, (20001103), vol. 55, no. 2, ISSN 0006-3525, pages 101 - 122, XP002267272 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/1097-0282(2000)55:2<101::AID-BIP20>3.0.CO;2-O
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