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Extract from the Register of European Patents

EP About this file: EP2251439

EP2251439 - Nucleic acid amplification method [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.07.2014
Database last updated on 13.07.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
Olink AB
Dag Hammarskjölds väg 54A
751 83 Uppsala / SE
[2010/46]
Inventor(s)01 / Landegren, Ulf
Norra Parkvägen 29
756 45 Uppsala / SE
02 / Gullberg, Mats
Rådjursstigen 64
191 46 Sollentuna / SE
03 / Nilsson, Mats
Allévägen 4
167 52 Bromma / SE
 [2010/46]
Representative(s)Dzieglewska, Hanna Eva
Dehns
St Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[N/P]
Former [2013/37]Dzieglewska, Hanna Eva
Dehns
St Bride's House
10 Salisbury Square
London
EC4Y 8JD / GB
Former [2010/46]Dzieglewska, Hanna Eva
Dehns St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Application number, filing date10003586.412.07.2002
[2010/46]
Priority number, dateGB2001001895903.08.2001         Original published format: GB 0118959
[2010/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2251439
Date:17.11.2010
Language:EN
[2010/46]
Type: B1 Patent specification 
No.:EP2251439
Date:11.09.2013
Language:EN
[2013/37]
Search report(s)(Supplementary) European search report - dispatched on:EP24.09.2010
ClassificationIPC:C12Q1/68
[2010/46]
CPC:
C12Q1/6848 (EP,US)
C-Set:
C12Q1/6848, C12Q2561/113, C12Q2531/125, C12Q2525/131 (US,EP);
C12Q1/6848, C12Q2561/125, C12Q2531/125, C12Q2525/131 (EP,US);
C12Q1/6848, C12Q2565/501, C12Q2531/125, C12Q2525/131 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2010/46]
TitleGerman:Verfahren zur Amplifikation von Nukleinsäure[2010/46]
English:Nucleic acid amplification method[2010/46]
French:Procédé d'amplification d'acide nucléique[2010/46]
Examination procedure16.05.2011Amendment by applicant (claims and/or description)
16.05.2011Examination requested  [2011/25]
05.08.2011Despatch of a communication from the examining division (Time limit: M04)
15.12.2011Reply to a communication from the examining division
26.03.2013Communication of intention to grant the patent
30.07.2013Fee for grant paid
30.07.2013Fee for publishing/printing paid
Parent application(s)   TooltipEP02741612.2  / EP1423532
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20020741612) is  01.12.2006
Opposition(s)12.06.2014No opposition filed within time limit [2014/34]
Fees paidRenewal fee
31.03.2010Renewal fee patent year 03
31.03.2010Renewal fee patent year 04
31.03.2010Renewal fee patent year 05
31.03.2010Renewal fee patent year 06
31.03.2010Renewal fee patent year 07
31.03.2010Renewal fee patent year 08
23.07.2010Renewal fee patent year 09
20.07.2011Renewal fee patent year 10
19.07.2012Renewal fee patent year 11
15.07.2013Renewal fee patent year 12
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
MC11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
TR11.09.2013
GR12.12.2013
PT13.01.2014
[2016/33]
Former [2016/25]AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
MC11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
PT13.01.2014
Former [2016/21]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
MC11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
PT13.01.2014
Former [2014/41]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
PT13.01.2014
Former [2014/38]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
PT13.01.2014
Former [2014/28]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
PT13.01.2014
Former [2014/24]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
Former [2014/23]BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
FI11.09.2013
NL11.09.2013
SE11.09.2013
SK11.09.2013
GR12.12.2013
Former [2014/22]BE11.09.2013
CY11.09.2013
FI11.09.2013
NL11.09.2013
SE11.09.2013
GR12.12.2013
Former [2014/18]BE11.09.2013
CY11.09.2013
FI11.09.2013
SE11.09.2013
GR12.12.2013
Former [2014/12]CY11.09.2013
FI11.09.2013
SE11.09.2013
GR12.12.2013
Former [2014/10]CY11.09.2013
SE11.09.2013
Former [2014/09]SE11.09.2013
Documents cited:Search[X]US6183960  (LIZARDI PAUL M [MX]) [X] 1-9 * col. 3, lines 14-30; col. 5, lines 20-23; col. 5, line 60 - col. 6, line 3; col. 7, lines 11-15; col. 10, line 39 - line 60; col. 11, lines 50-67; col. 21, line 33 - col. 22, line 23; col. 23, lines 5-40 *;
 [X]WO9949079  (LANDEGREN ULF [SE]) [X] 1-3,6-9 * page 13, lines 9-29; Fig. 5 *;
 [A]WO0006778  (NEW YORK HEALTH RES INST [US]) [A] 1-9 * the whole document *
 [A]  - LIZARDI P M ET AL, "MUTATION DETECTION AND SINGLE-MOLECULE COUNTING USING ISOTHERMAL ROLLING-CIRCLE AMPLIFICATION", NATURE GENETICS, NATURE PUBLISHING GROUP, NEW YORK, US LNKD- DOI:10.1038/898, (19980701), vol. 19, no. 3, ISSN 1061-4036, pages 225 - 232, XP000856939 [A] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1038/898
by applicantUS5854033
 US6124120
 US6143495
 US6183960
 US6210884
 WO9949079
 WO9201813
 US5714320
 JPH04304900
 WO0036141
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    - CARMI N.; BALKHI S. R.; BREAKER R. R., "Cleaving DNA with DNA", PROC NATL ACAD SCI U S A, (1998), vol. 95, pages 2233 - 7
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DOI:   http://dx.doi.org/10.1038/375611a0
    - DAUBENDIEK, S.L.; KOOL, E.T., "Generation of catalytic RNAs by rolling transcription of synthetic DNA nanocirdes", NAT BIOTECHNOL, (1997), vol. 15, doi:doi:10.1038/nbt0397-273, pages 273 - 277, XP002071364

DOI:   http://dx.doi.org/10.1038/nbt0397-273
    - DAUWERSE, J.G.; WIEGANT, J.; RAAP, A.K.; BREUNING, M.H.; VAN OMMEN, G.-J.B., "Multiple colors by fluorescence in situ hybridization using ratio-labelled DNA probes create a molecular karyotype", HUM MOL GENET, (1992), vol. 1, pages 593 - 598
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DOI:   http://dx.doi.org/10.1038/898
    - LYAMICHEV V.; MAST A. L.; HALL J. G.; PRUDENT J. R.; KAISER M. W.; TAKOVA T.; KWIATKOWSKI R. W.; SANDER T. J.; DE ARRUDA M.; ARCO, "Polymorphism identification and quantitative detection of genomic DNA by invasive cleavage of oligonucleotide probes", NAT. BIOTECHNOL., (1999), vol. 17, doi:doi:10.1038/7044, pages 292 - 296, XP002121762

DOI:   http://dx.doi.org/10.1038/7044
    - NEDERLOF, P.M.; VAN, D.F.S.; VROLIJK, J.; TANKE, H.J.; RAAP, A.K., "Fluorescence ratio measurements of double-labeled probes for multiple in situ hybridization by digital imaging microscopy", CYTOMETRY, (1992), vol. 13, doi:doi:10.1002/cyto.990130806, pages 839 - 845, XP002964616

DOI:   http://dx.doi.org/10.1002/cyto.990130806
    - NILSSON, M.; MALMGREN, H.; SAMIOTAKI, M.; KWIATKOWSKI, M.; CHOWDHARY, B.P.; LANDEGREN, U., "Padlock probes: Circularizing oligonucleotides for localized DNA detection", SCIENCE, (1994), vol. 265, pages 2085 - 2088
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DOI:   http://dx.doi.org/10.1038/nbt0396-303
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