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Extract from the Register of European Patents

EP About this file: EP2279746

EP2279746 - SURFACE PROTEINS IN NEISSERIA MENINGITIDIS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.08.2014
Database last updated on 13.07.2024
Most recent event   Tooltip30.08.2019Change - lapse in a contracting statepublished on 02.10.2019  [2019/40]
Applicant(s)For all designated states
Novartis Vaccines and Diagnostics S.r.l.
Via Fiorentina 1
53100 Siena (SI) / IT
[2011/05]
Inventor(s)01 / Norais, Nathalie
Novartis Vaccines
Via Fiorentina 1
53100 Siena / IT
02 / Grandi, Guido
Novartis Vaccines
Via Fliorentina 1
53100 Siena / IT
 [2013/40]
Former [2011/05]01 / Norais, Nathalie
Novartis Vaccines Via Fiorentina 1
53100 Siena / IT
02 / Grandi, Guido
Novartis Vaccines Via Fliorentina 1
53100 Siena / IT
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2013/40]
Former [2011/05]Carpmaels & Ransford
One Southampton Row London
WC1B 5HA / GB
Application number, filing date10004682.017.11.2003
[2011/05]
Priority number, dateGB2002002673415.11.2002         Original published format: GB 0226734
GB2003000713127.03.2003         Original published format: GB 0307131
[2011/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2279746
Date:02.02.2011
Language:EN
[2011/05]
Type: A3 Search report 
No.:EP2279746
Date:25.05.2011
[2011/21]
Type: B1 Patent specification 
No.:EP2279746
Date:02.10.2013
Language:EN
[2013/40]
Search report(s)(Supplementary) European search report - dispatched on:EP29.04.2011
ClassificationIPC:A61K39/095, C07K14/22
[2011/05]
CPC:
C07K14/22 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2011/05]
TitleGerman:OBERFLÄCHENPROTEINE IN NEISSERIA MENINGITIDIS[2011/05]
English:SURFACE PROTEINS IN NEISSERIA MENINGITIDIS[2011/05]
French:PROTEINES DE SURFACE DE NEISSERIA MENINGITIDIS[2011/05]
Examination procedure25.11.2011Amendment by applicant (claims and/or description)
25.11.2011Examination requested  [2012/07]
24.02.2012Despatch of a communication from the examining division (Time limit: M04)
12.06.2012Reply to a communication from the examining division
06.07.2012Despatch of a communication from the examining division (Time limit: M06)
14.01.2013Reply to a communication from the examining division
03.04.2013Communication of intention to grant the patent
02.08.2013Fee for grant paid
02.08.2013Fee for publishing/printing paid
Parent application(s)   TooltipEP03780503.3  / EP1562982
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030780503) is  07.11.2008
Opposition(s)03.07.2014No opposition filed within time limit [2014/37]
Fees paidRenewal fee
04.05.2010Renewal fee patent year 03
04.05.2010Renewal fee patent year 04
04.05.2010Renewal fee patent year 05
04.05.2010Renewal fee patent year 06
04.05.2010Renewal fee patent year 07
12.11.2010Renewal fee patent year 08
14.11.2011Renewal fee patent year 09
13.11.2012Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU17.11.2003
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
GR02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
LU17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
GB02.01.2014
DK31.01.2014
NL01.06.2014
DE03.06.2014
[2019/40]
Former [2015/38]HU17.11.2003
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
GR02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
LU17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
GB02.01.2014
DK31.01.2014
NL01.06.2014
DE03.06.2014
Former [2015/34]HU17.11.2003
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
LU17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
GB02.01.2014
DK31.01.2014
NL01.06.2014
DE03.06.2014
Former [2015/08]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
GB02.01.2014
DK31.01.2014
NL01.06.2014
DE03.06.2014
Former [2014/51]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
GB02.01.2014
NL01.06.2014
DE03.06.2014
Former [2014/48]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
IE17.11.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
NL01.06.2014
DE03.06.2014
Former [2014/42]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
SE18.11.2013
BE30.11.2013
CH30.11.2013
LI30.11.2013
NL01.06.2014
DE03.06.2014
Former [2014/39]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
SE18.11.2013
CH30.11.2013
LI30.11.2013
NL01.06.2014
DE03.06.2014
Former [2014/38]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
IT02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
SE18.11.2013
CH30.11.2013
LI30.11.2013
DE03.06.2014
Former [2014/37]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
RO02.10.2013
SI02.10.2013
SK02.10.2013
SE18.11.2013
CH30.11.2013
LI30.11.2013
DE03.06.2014
Former [2014/36]CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
SI02.10.2013
CH30.11.2013
LI30.11.2013
Former [2014/34]CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
SI02.10.2013
CH30.11.2013
LI30.11.2013
Former [2014/26]CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
SI02.10.2013
Former [2014/24]CZ02.10.2013
ES02.10.2013
FI02.10.2013
SI02.10.2013
Former [2014/23]CZ02.10.2013
FI02.10.2013
SI02.10.2013
Former [2014/22]FI02.10.2013
SI02.10.2013
Former [2014/12]SI02.10.2013
Documents cited:Search[Y]WO0025811  (MICROBIOLOGICAL RES AUTHORITY [GB], et al) [Y] 1-13 * page 2 - page 6 *;
 [XY]WO0071725  (CHIRON SPA [IT], et al) [X] 9-13 * pages 2,3,55; example -; claim -; sequence 8012 * [Y] 1-13;
 [A]WO0109350  (SMITHKLINE BEECHAM BIOLOG [BE], et al) [A] 1-13 * examples 3-5 *;
 [Y]WO0152885  (CHIRON SPA [IT], et al) [Y] 1-13 * page 2 - page 10 * * page 50 - page 52 *;
 [Y]  - CLAASSEN I ET AL, "Production, characterization and control of a Neisseria meningitidis hexavalent class 1 outer membrane protein containing vesicle vaccine", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, (19960701), vol. 14, no. 10, ISSN 0264-410X, pages 1001 - 1008, XP004057632 [Y] 1-13 * page 1002, column L * * same citations *

DOI:   http://dx.doi.org/10.1016/0264-410X(96)00020-5
 [A]  - VAN DER LEY P ET AL, "Construction of Neisseria meningitidis strains carrying multiple chromosomal copies of the porA gene for use in the production of a multivalent outer membrane vesicle vaccine", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, (1995), vol. 13, no. 4, ISSN 0264-410X, pages 401 - 407, XP004057740 [A] 1-13 * page 404, column R, paragraph 2 - page 405, column R, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/0264-410X(95)98264-B
 [Y]  - NORAIS NATHALIE ET AL, "Combined automated PCR cloning, in vitro transcription/translation and two-dimensional electrophoresis for bacterial proteome analysis", PROTEOMICS, (200111), vol. 1, no. 11, ISSN 1615-9853, pages 1378 - 1389, XP009032238 [Y] 1-13 * page 1382, column L, paragraph 1 - page 1383, column L, paragraph 1; table 2 *

DOI:   http://dx.doi.org/10.1002/1615-9861(200111)1:11<1378::AID-PROT1378>3.0.CO;2-S
 [XY]  - TETTELIN H ET AL, "COMPLETE GENOME SEQUENCE OF NEISSERIA MENINGITIDIS SEROGROUP B STRAIN MC58", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, (2000), vol. 287, ISSN 0036-8075, pages 1809 - 1815, XP000914963 [X] 9-13 * the whole document * [Y] 1-13

DOI:   http://dx.doi.org/10.1126/science.287.5459.1809
 [XY]  - TETTELIN ET AL., "SubName: Full=Putative uncharacterized protein", UniProt, EBI, (20001001), Database accession no. Q9JY11, XP002610937 [X] 9-13 * the whole document * [Y] 1-13
 [A]  - GRIFANTINI R ET AL, "Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, (200209), vol. 20, no. 9, ISSN 1087-0156, pages 914 - 921, XP002272872 [A] 1-13 * page 917, column R, paragraph 2 - page 918, column L, paragraph 1; figure 2; tables 2,3 *

DOI:   http://dx.doi.org/10.1038/nbt728
 [A]  - PIZZA M ET AL, "IDENTIFICATION OF VACCINE CANDIDATES AGAINST SEROGROUP B MENINGOCOCCUS BY WHOLE-GENOME SEQUENCING", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, (20000310), vol. 287, no. 5459, ISSN 0036-8075, pages 1816 - 1820, XP000986271 [A] 1-13 * page 1817 - page 1818; table 1 *

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 [A]  - JOLLEY KEITH A ET AL, "Immunization with recombinant Opc outer membrane protein from Neisseria meningitidis: Influence of sequence variation and levels of expression on the bactericidal immune response against meningococci", INFECTION AND IMMUNITY, (200106), vol. 69, no. 6, ISSN 0019-9567, pages 3809 - 3916, XP002284891 [A] 1-13 * page 3810 *

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 [A]  - WRIGHT J CLAIRE ET AL, "Immunization with the recombinant PorB outer membrane protein induces a bactericidal immune response against Neisseria meningitidis", INFECTION AND IMMUNITY, (200208), vol. 70, no. 8, ISSN 0019-9567, pages 4028 - 4034, XP002284892 [A] 1-13 * page 4029 *

DOI:   http://dx.doi.org/10.1128/IAI.70.8.4028-4034.2002
 [A]  - POLLARD A J ET AL, "The meningococcus tamed?", ARCHIVES OF DISEASE IN CHILDHOOD. ENGLAND JUL 2002, (200207), vol. 87, no. 1, ISSN 1468-2044, pages 13 - 17, XP002284893 [A] 1-13 * page 15; table 2 *

DOI:   http://dx.doi.org/10.1136/adc.87.1.13
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