EP2305710 - Synthetic antibody phage libraries [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 09.10.2020 Database last updated on 30.10.2024 | |
Former | Examination is in progress Status updated on 16.01.2017 | Most recent event Tooltip | 09.10.2020 | Application deemed to be withdrawn | published on 11.11.2020 [2020/46] | Applicant(s) | For all designated states Genentech, Inc. 1 DNA Way South San Francisco, CA 94080-4990 / US | [N/P] |
Former [2011/14] | For all designated states Genentech, Inc. 1 DNA Way South San Francisco CA 94080-4990 / US | Inventor(s) | 01 /
Fuh, Germaine, G. 149 Amapola Avenue Pacifica CA 94044 / US | 02 /
Sidhu, Sachdev, S. 135 Brunswick Ave. Toronto, Ontario, M5S 2M3 / CA | [2011/25] |
Former [2011/14] | 01 /
Fuh, Germaine, G. 149 Amapola Avenue Pacifica CA 94044 / US | ||
02 /
Sidhu, Sachdev, S. 150 Freelon Street San Francisco CA 94107 / US | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [N/P] |
Former [2011/14] | Denison, Christopher Marcus, et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS / GB | Application number, filing date | 10011041.0 | 03.06.2003 | [2011/14] | Priority number, date | US20020385338P | 03.06.2002 Original published format: US 385338 P | US20030463656P | 16.04.2003 Original published format: US 463656 P | [2011/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2305710 | Date: | 06.04.2011 | Language: | EN | [2011/14] | Type: | A3 Search report | No.: | EP2305710 | Date: | 29.05.2013 | Language: | EN | [2013/22] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 29.04.2013 | Classification | IPC: | C07K16/22, C07K16/32, C07K16/42, C07K16/00, C40B40/10 | [2013/07] | CPC: |
C07K16/32 (EP,US);
C07K16/44 (KR);
A61P17/02 (EP);
A61P19/08 (EP);
A61P35/00 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/02 (EP);
A61P9/10 (EP);
C07K14/47 (KR);
C07K16/22 (EP,US);
C07K16/4283 (EP,US);
C07K19/00 (KR);
G01N33/53 (KR);
C07K2317/24 (EP,US);
C07K2317/54 (EP,US);
C07K2317/55 (EP,US);
C07K2317/565 (EP,US);
C07K2317/622 (EP,US)
(-)
|
Former IPC [2011/14] | C07K16/22, C07K16/32, C07K16/42 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR [2011/14] | Title | German: | Synthetische Antikörperphagenbibliotheken | [2011/14] | English: | Synthetic antibody phage libraries | [2011/14] | French: | Bibliothèques de phages et anticorps synthétiques | [2011/14] | Examination procedure | 22.11.2013 | Amendment by applicant (claims and/or description) | 22.11.2013 | Examination requested [2014/01] | 09.06.2016 | Despatch of a communication from the examining division (Time limit: M06) | 27.03.2017 | Reply to a communication from the examining division | 20.11.2017 | Despatch of a communication from the examining division (Time limit: M06) | 02.03.2018 | Observations by third parties | 29.05.2018 | Reply to a communication from the examining division | 12.04.2019 | Despatch of a communication from the examining division (Time limit: M04) | 06.08.2019 | Reply to a communication from the examining division | 04.02.2020 | Despatch of a communication from the examining division (Time limit: M04) | 16.06.2020 | Application deemed to be withdrawn, date of legal effect [2020/46] | 08.07.2020 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2020/46] | Parent application(s) Tooltip | EP03734379.5 / EP1513879 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030734379) is 08.09.2008 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 27.03.2017 | Request for further processing filed | 27.03.2017 | Full payment received (date of receipt of payment) Request granted | 05.04.2017 | Decision despatched | Fees paid | Renewal fee | 18.01.2011 | Renewal fee patent year 03 | 18.01.2011 | Renewal fee patent year 04 | 18.01.2011 | Renewal fee patent year 05 | 18.01.2011 | Renewal fee patent year 06 | 18.01.2011 | Renewal fee patent year 07 | 18.01.2011 | Renewal fee patent year 08 | 13.06.2011 | Renewal fee patent year 09 | 24.05.2012 | Renewal fee patent year 10 | 31.03.2013 | Renewal fee patent year 11 | 31.03.2014 | Renewal fee patent year 12 | 05.06.2015 | Renewal fee patent year 13 | 31.03.2016 | Renewal fee patent year 14 | 08.06.2017 | Renewal fee patent year 15 | 08.06.2018 | Renewal fee patent year 16 | 10.06.2019 | Renewal fee patent year 17 | 31.03.2020 | Renewal fee patent year 18 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A] - GARRARD & D J HENNER L J, "Selection of an anti-IGF-1 Fab from a Fab phage library created by mutagenesis of multiple CDR loops", GENE, ELSEVIER, AMSTERDAM, NL, (19930101), vol. 128, doi:10.1016/0378-1119(93)90160-5, ISSN 0378-1119, pages 103 - 109, XP025516241 [A] 1-36 * page 104, column 1, paragraph 2 - page 105; tables 1-4 * DOI: http://dx.doi.org/10.1016/0378-1119(93)90160-5 | [A] - PINI A ET AL, "Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (19980821), vol. 273, no. 34, doi:10.1074/JBC.273.34.21769, ISSN 0021-9258, pages 21769 - 21776, XP002124781 [A] 1-36 * page 21770, column 1 * DOI: http://dx.doi.org/10.1074/jbc.273.34.21769 | [A] - KNAPPIK A ET AL, "Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20000211), vol. 296, no. 1, doi:10.1006/JMBI.1999.3444, ISSN 0022-2836, pages 57 - 86, XP004461525 [A] 1-36 DOI: http://dx.doi.org/10.1006/jmbi.1999.3444 | [A] - WU H ET AL, "STEPWISE IN VITRO AFFINITY MATURATION OF VITAXIN, AN ALPHAVBETA3-SPECIFIC HUMANIZED MAB", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, (19980501), vol. 95, doi:10.1073/PNAS.95.11.6037, ISSN 0027-8424, pages 6037 - 6042, XP000918969 [A] 1-36 DOI: http://dx.doi.org/10.1073/pnas.95.11.6037 | [T] - SIDHU S S ET AL, "Phage-displayed Antibody Libraries of Synthetic Heavy Chain Complementarity Determining Regions", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20040423), vol. 338, no. 2, doi:10.1016/J.JMB.2004.02.050, ISSN 0022-2836, pages 299 - 310, XP004500301 DOI: http://dx.doi.org/10.1016/j.jmb.2004.02.050 | [T] - FUH GERMAINE, "Synthetic antibodies as therapeutics", EXPERT OPINION ON BIOLOGICAL THERAPY, ASHLEY, LONDON, GB, (20070101), vol. 7, no. 1, ISSN 1471-2598, pages 73 - 87, XP009099132 [T] * page 76 - page 78 * | by applicant | EP0266032 | EP0404097 | WO9201047 | WO9220791 | WO9306213 | WO9311161 | WO9311236 | WO9319172 | EP0368684 | US5427908 | US5432018 | US5498530 | US5534615 | US5580717 | US5658727 | US5667780 | US5688666 | US5723286 | US5733743 | US5750373 | US5821337 | US5837242 | US5969108 | WO0006717 | US6054297 | US6172197 | - BASS, S., PROTEINS, (1990), vol. 8, page 309 | - LOWMAN; WELLS, METHODS: A COMPANION TO METHODS IN ENZYMOLOGY, (1991), vol. 3, page 205 | - SMITH ET AL., SCIENCE, (1985), vol. 228, page 1315 | - SKERRA; PLUCKTHUN, SCIENCE, (1988), vol. 240, page 1038 | - HOGENBOOM, IMMUNOTECHNIQUES, (1988), vol. 4, pages 1 - 20 | - BARBAS; BURTON, TRENDS BIOTECH, (1996), vol. 14, page 230 | - GRIFFITHS ET AL., EMBO J., (1994), vol. 13, page 3245 | - VAUGHAN ET AL., NAT. BIOTECH., (1996), vol. 14, page 309 | - VAUGHAN ET AL., NATURE BIOTECH, (1996), vol. 14, page 309 | - KNAPPIK ET AL., J. MOL. BIOL., (1999), vol. 296, page 57 | - DENG ET AL., J. BIOL. CHEM., (1994), vol. 269, page 9533 | - ULRICH ET AL., PNAS, (1995), vol. 92, pages 11907 - 11911 | - FORSBERG ET AL., J. BIOL. CHEM., (1997), vol. 272, page 12430 | - TOMLINSON, NATURE BIOTECH., (2000), vol. 18, pages 989 - 994 | - BARBAS, PNAS, (1994), vol. 91, page 3809 | - YELTON, DE, J. IMMUNOLOGY, (1995), vol. 155, page 1994 | - JACKSON, J.R., J. IMMUNOLOGY, (1995), vol. 154, page 3310 | - HAWKINS, RE, J. MOL. BIOLOGY, (1992), vol. 226, page 889 | - GARRARD; HENNER, GENE, (1993), vol. 128, page 103 | - Sequences of Proteins of Immunological Interest, U.S. NATIONAL INSTITUTES OF HEALTH | - CHOTHIA; LESK, J. MOL. BIOL., (1987), vol. 196, pages 901 - 917 | - KNAPPEK ET AL., J. MOL. BIOL., (1999), vol. 296, pages 57 - 86 | - PLUCKTHUN, The Pharmacology of Monoclonal Antibodies, SPRINGER-VERLAG, (1994), vol. 113, pages 269 - 315 | - HOLLINGER ET AL., PROC. NATL. ACAD. SCI. USA, (1993), vol. 90, pages 6444 - 6448 | - ZAPATA ET AL., PROTEIN ENG., (1995), vol. 8, no. 10, pages 1057 - 1062 | - WELLS; LOWMAN, CURR. OPIN. STRUCT. BIOL., (1992), vol. 3, pages 355 - 362 | - LOWMAN; WELLS, METHODS: A COMPANION TO METHODS IN ENZYMOLOGY, (1991), vol. 3, pages 205 - 0216 | - FROESHLER ET AL., NUCL. ACIDS, RES., (1986), vol. 14, pages 5399 - 5407 | - ENGELS ET AL., AGNEW. CHEM. INT. ED. ENGL., (1989), vol. 28, pages 716 - 734 | - LEE; RICHARDS, J. MOL. BIOL., (1971), vol. 55, page 379 | - CONNOLLY, J. APPL. CRYST., (1983), vol. 16, page 548 | - PACIOS, "ARVOMOL/CONTOUR: molecular surface areas and volumes on Personal Computers", COMPUT. CHEM., (1994), vol. 18, no. 4, pages 377 - 386 | - "Variations of Surface Areas and Volumes in Distinct Molecular Surfaces of Biomolecules", J. MOL. MODEL., (1995), vol. 1, pages 46 - 53 | - CARTER ET AL., PNAS, (1992), vol. 89, page 4285 | - J MOL. BIOL., (1993), vol. 229, page 969 | - "Variations of Surface Areas and Volumes in Distinct Molecular Surfaces of Biomolecules", J MOL. MODEL., (1995), vol. 1, pages 46 - 53 | - KUNKEL ET AL., METHODS ENZYMOL., (1987), vol. 154, pages 367 - 382 | - ZOLLER ET AL., NUCLEIC ACIDS RES., (1987), vol. 10, pages 6487 - 6504 | - CREA ET AL., PROC. NAT'L. ACAD. SCI. USA, (1978), vol. 75, page 5765 | - VIERA ET AL., METH. ENZYMOL., (1987), vol. 153, page 3 | - J IMMUNOL METHODS., (19991210), vol. 231, no. 1-2, pages 39 - 51 | - PROTEIN SCI, (200004), vol. 9, no. 4, pages 647 - 54 | - J VIROL., (200108), vol. 75, no. 15, pages 7107 - 13 | - NAT BIOTECHNOL., (200101), vol. 19, no. 1, pages 75 - 8 | - NUCLEIC ACIDS RES., (20010515), vol. 29, no. 10, pages E50 - 0 | - WONG ET AL., GENE, (1983), vol. 68, page 1931 | - CHANG ET AL., GENE, (1987), vol. 55, page 189 | - DAVIS ET AL., Microbiology, HARPER & ROW, (1980), pages 237,245 - 47,374 | - BULLOCK ET AL., BIOTECHNIQUES, (1987), vol. 5, pages 376 - 379 | - H. R. HOOGENBOOM; G. WINTER, J. MOL. BIOL., (1992), vol. 227, pages 381 - 388 | - SIDHU ET AL., METHODS ENZYMOL, (2000), vol. 328, pages 333 - 363 | - METHODS IN ENZYMOLOGY, (1976), page 44 | - SIDHU ET AL., J. MOL. BIOL., (2000), vol. 296, pages 487 - 495 | - SIDHU ET AL., METHODS ENZYMOL., (2000), vol. 328, pages 333 - 363 | - BASS ET AL., PROTEINS, (1990), vol. 8, pages 309 - 314 | - CARTER ET AL., PNAS, (1992), vol. 89, pages 4285 - 4289 | - GRAY ET AL., J. MOL. BIOL., (1981), vol. 146, pages 621 - 627 | - CRISSMAN, VIROLOGY, (1984), vol. 132, pages 445 - 455 | - WIESMANN ET AL., CELL, (1997), vol. 91, pages 695 - 704 | - FUH ET AL., J. BIOL. CHEM., (1998), vol. 273, pages 11197 - 11204 |