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Extract from the Register of European Patents

EP About this file: EP2338913

EP2338913 - Chromosome 13-linked breast cancer susceptibility gene [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.11.2015
Database last updated on 02.11.2024
Most recent event   Tooltip04.11.2015Application deemed to be withdrawnpublished on 02.12.2015  [2015/49]
Applicant(s)For all designated states
The University of Utah Research Foundation
615 Arapeen Drive, Suite 310
Salt Lake City, Utah 84108 / US
For all designated states
Endo Recherche Inc.
2989 de la Promenade Sainte-Foy
Quebec G1W 2J5 / CA
For all designated states
The Trustees of The University of Pennsylvania
3700 Market Street, Suite 300
Philadelphia, Pennsylvania 19104 / US
For all designated states
HSC Research and Development Limited Partnership
555 University Avenue, Suite 5270 Toronto
Ontario M5G 1X8 / CA
[N/P]
Former [2011/26]For all designated states
The University of Utah Research Foundation
615 Arapeen Drive, Suite 310 Salt Lake City
Utah 84108 / US
For all designated states
Endo Recherche Inc.
2989 de la Promenade Sainte-Foy
Quebec G1W 2J5 / CA
For all designated states
The Trustees of The University of Pennsylvania
3700 Market Street, Suite 300
Philadelphia, Pennsylvania 19104 / US
For all designated states
HSC Research and Development Limited Partnership
555 University Avenue, Suite 5270 Toronto
Ontario M5G 1X8 / CA
Inventor(s)01 / Tavtigian, Sean V.
557 East 1st Avenue Apt. 3
Salt Lake City, UT 84103 / US
02 / Kamb, Alexander
1103 East 600 South
Salt Lake City, UT 84102 / US
03 / Simard, Jacques
4808 Pilet
St-Augustin de Desmaures Québec G3A 1Z9 / CA
04 / Couch, Fergus
250 Iven Avenue Apt. 2B
St. David, PA 19087 / US
05 / Rommens, Johanna M.
10 McCaul Street
Toronto Ontario M5T 2X4 / CA
06 / Weber, Barbara L.
331 Mallwyd Road
Merion, PA 19066 / US
 [2011/26]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2011/26]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date10158057.917.12.1996
[2011/26]
Priority number, dateUS1995057377918.12.1995         Original published format: US 573779
US1995057535920.12.1995         Original published format: US 575359
US1995057655921.12.1995         Original published format: US 576559
US1996058539111.01.1996         Original published format: US 585391
US1996063950129.04.1996         Original published format: US 639501
[2011/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2338913
Date:29.06.2011
Language:EN
[2011/26]
Search report(s)(Supplementary) European search report - dispatched on:EP09.05.2011
ClassificationIPC:C07K14/82, C12Q1/68, G01N33/53, A01K67/027
[2011/26]
CPC:
C07K14/4703 (EP,US); A61K48/00 (EP,US); Y10S530/828 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2011/26]
TitleGerman:Chromosom 13 verbundene Brustkrebsempfindlichkeitsgen BRCA2[2011/26]
English:Chromosome 13-linked breast cancer susceptibility gene[2011/26]
French:Gène BRCA2 impliqué dans la susceptibilité au cancer du sein , du chromosome 13[2011/26]
Examination procedure30.11.2011Amendment by applicant (claims and/or description)
30.11.2011Examination requested  [2012/02]
04.12.2012Observations by third parties
17.04.2013Despatch of a communication from the examining division (Time limit: M04)
26.08.2013Reply to a communication from the examining division
01.07.2015Application deemed to be withdrawn, date of legal effect  [2015/49]
28.07.2015Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2015/49]
Parent application(s)   TooltipEP02006768.2  / EP1260520
EP96309211.9  / EP0785216
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19960309211) is  05.03.1999
Fees paidRenewal fee
26.03.2010Renewal fee patent year 03
26.03.2010Renewal fee patent year 04
26.03.2010Renewal fee patent year 05
26.03.2010Renewal fee patent year 06
26.03.2010Renewal fee patent year 07
26.03.2010Renewal fee patent year 08
26.03.2010Renewal fee patent year 09
26.03.2010Renewal fee patent year 10
26.03.2010Renewal fee patent year 11
26.03.2010Renewal fee patent year 12
26.03.2010Renewal fee patent year 13
26.03.2010Renewal fee patent year 14
22.11.2010Renewal fee patent year 15
07.12.2011Renewal fee patent year 16
07.12.2012Renewal fee patent year 17
06.12.2013Renewal fee patent year 18
Penalty fee
Additional fee for renewal fee
31.12.201419   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[E]WO9719110  (CANCER RES CAMPAIGN TECH [GB], et al) [E] 1-10 * abstract * * page 8, lines 4-22 * * page 4, lines 20-32 * * page 6, lines 22-26 * * page 24, line 34 - page 25, line 2 * * page 27, line 11 - page 28, line 23 * * page 44, line 10 - page 46, line 20 * * claims 15,50 *;
 [YP]  - WOOSTER R ET AL, "IDENTIFICATION OF THE BREAST-CANCER SUSCEPTIBILITY GENE BRCA2", NATURE, (199512), vol. 378, pages 789 - 792, XP002029512 [YP] 1-10 * abstract * * page 790, column 1, paragraph 1 - page 792, column 1, paragraph 3 * * figures 1,2 *

DOI:   http://dx.doi.org/10.1038/378789a0
 [Y]  - MIKI Y ET AL, "A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.", SCIENCE, UNITED STATES, (19941007), vol. 266, pages 66 - 71, XP000202410 [Y] 1-10 * page 66 * * page 71, column L, paragraph 2 *

DOI:   http://dx.doi.org/10.1126/science.7545954
 [A]  - WOOSTER R ET AL, "Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.", SCIENCE,, UNITED STATES, (19940930), vol. 265, pages 2088 - 2090, XP002029509 [A] 1-10 * abstract *

DOI:   http://dx.doi.org/10.1126/science.8091231
 [A]  - GUDMUNDSSON J ET AL, "Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.", CANCER RES, UNITED STATES, (19951101), vol. 55, pages 4830 - 4832, XP002029510 [A] 1-10 * abstract *
 [A]  - KERANGUEVEN F ET AL, "Patterns of loss of heterozygosity at loci from chromosome arm 13q suggests a possible involvement of BRCA2 in sporadic breast tumors.", GENES, CHROMOSOMES & CANCER. UNITED STATES AUG 1995, (199508), vol. 13, no. 4, ISSN 1045-2257, pages 291 - 294, XP008009196 [A] 1-10 * the whole document *
 [X]  - FOSTER KA ET AL, "SOMATIC AND GERMLINE MUTATIONS OF THE BRCA2 GENE IN SPORADIC OVARIAN-CANCER", CANCER RESEARCH, (1996), vol. 56, pages 3622 - 3625, XP002029513 [X] 1-10 * abstract *
 [XP]  - BERMAN D. ET AL., "A COMMON MUTATION IN BRCA2 THAT PREDISPOSES TO A VARIETY OF CANCERS IS FOUND IN BOTH JEWISH ASHKENAZI AND NON-JEWISH INDIVIDUALS", CANCER RESEARCH, (199608), vol. 56, pages 3409 - 3414, XP002029514 [XP] 1-10 * abstract *
 [X]  - JACOB ANK ET AL, "ISOLATION OF EXPRESSED SEQUENCES THAT INCLUDE A GENE FOR FAMILIAL BREAST-CANCER (BRCA2) AND OTHER NOVEL TRANSCRIPTS FROM A 5-MEGABASE REGION ON CHROMOSOME 13Q12", ONCOGENE, 1996, 13, 213-221, (1996), vol. 13, pages 213 - 221, XP000618318 [X] 1-10 * abstract *
 [X]  - COUCH FJ ET AL, "GENERATION OF AN INTEGRATED TRANSCRIPTION MAP OF THE BRCA2 REGION ON CHROMOSOME 13Q12-Q13", GENOMICS, (1996), vol. 36, pages 86 - 99, XP000647994 [X] 1-10 * abstract *

DOI:   http://dx.doi.org/10.1006/geno.1996.0428
 [XP]  - TAVTIGIAN S V ET AL, "The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds", NATURE GENETICS, NEW YORK, NY, US, (19960301), vol. 3, no. 12, ISSN 1061-4036, pages 333 - 337, XP002076942 [XP] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1038/ng0396-333
 [XP]  - NEUHAUSEN S ET AL, "Recurrent BRCA2 6174delT mutations in Ashkenazi jewish women affected by breast cancer", NATURE GENETICS, NEW YORK, NY, US, (1996), vol. 13, ISSN 1061-4036, pages 126 - 128, XP002091558 [XP] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1038/ng0596-126
 [A]  - THOMPSON M E ET AL, "DECREASED EXPRESSION OF BRCA1 ACCELERATES GROWTH AND IS OFTEN PRESENT DURING SPORADIC BREAST CANCER PROGRESSION", NATURE GENETICS, NATURE PUBLISHING GROUP, NEW YORK, US, (19950401), vol. 9, no. 4, doi:10.1038/NG0495-444, ISSN 1061-4036, pages 444 - 450, XP001011260 [A] 1-10 * abstract * * page 444, column 2, paragraphs 2,3 * * page 446, column 1, paragraph 2 - page 447, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1038/ng0495-444
 [A]  - BROWN M A ET AL, "Regulation of BRCA1", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, (19941222), vol. 372, no. 6508, doi:10.1038/372733A0, ISSN 0028-0836, page 733, XP002283560 [A] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1038/372733a0
by applicantUS3817837
 US3850752
 US3939350
 US3996345
 US4275149
 US4277437
 US4366241
 US4376110
 EP0073675
 WO8403564
 US4486530
 EP0225807
 US4683195
 US4683202
 US4816567
 EP0332435
 US4868105
 WO9307282
 US5252479
 WO9719110
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