EP2295551 - Thermostable reverse transcriptases and uses thereof [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 10.02.2017 Database last updated on 09.09.2024 | Most recent event Tooltip | 13.07.2018 | Lapse of the patent in a contracting state New state(s): CY, LU, TR | published on 15.08.2018 [2018/33] | Applicant(s) | For all designated states Life Technologies Corporation 5823 Newton Drive Carlsbad, CA 92008 / US | [2016/47] |
Former [2011/11] | For all designated states Life Technologies Corporation 5791 Van Allen Way Carlsbad, CA 92008 / US | Inventor(s) | 01 /
Smith, Michael D. 14005 Shippers Lane Rockville, MD 20853 / US | 02 /
Potter, Robert Jason 6519 Himes Avenue Frederick, MD 21703 / US | 03 /
Dhariwal, Gulshan 10612 Maplecrest Lane Potomac, MD 20854 / US | 04 /
Gerard, Gary F. 8393 William Drive Frederick, MD 21704 / US | 05 /
Rosenthal, Kim 25525 Long Corner Road Laytonsville, MD 20882 / US | [2011/11] | Representative(s) | Weber, Birgit, et al Life Technologies GmbH Frankfurter Strasse 129 B 64293 Darmstadt / DE | [2016/14] |
Former [2012/43] | Weber, Birgit, et al Life Technologies GmbH Frankfurter Strasse 129 B 64293 Darmstadt / DE | ||
Former [2011/11] | Harrison Goddard Foote 4th Floor Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG / GB | Application number, filing date | 10167769.8 | 25.05.2001 | [2011/11] | Priority number, date | US20000207196P | 26.05.2000 Original published format: US 207196 P | US20010808124 | 15.03.2001 Original published format: US 808124 | US20010845157 | 01.05.2001 Original published format: US 845157 | [2011/11] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2295551 | Date: | 16.03.2011 | Language: | EN | [2011/11] | Type: | B1 Patent specification | No.: | EP2295551 | Date: | 06.04.2016 | Language: | EN | [2016/14] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.01.2011 | Classification | IPC: | C12N9/12 | [2011/11] | CPC: |
C12N9/1276 (EP)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2016/14] |
Former [2011/11] | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR | Extension states | AL | 29.06.2010 | LT | 29.06.2010 | LV | 29.06.2010 | MK | 29.06.2010 | RO | 29.06.2010 | SI | 29.06.2010 | Title | German: | Thermostabile reverse Transkriptase und deren Anwendungen | [2011/11] | English: | Thermostable reverse transcriptases and uses thereof | [2011/11] | French: | Transcriptases inverses thermostables et utilisations | [2011/11] | Examination procedure | 16.09.2011 | Amendment by applicant (claims and/or description) | 16.09.2011 | Examination requested [2011/43] | 24.03.2015 | Despatch of a communication from the examining division (Time limit: M04) | 01.07.2015 | Reply to a communication from the examining division | 12.11.2015 | Communication of intention to grant the patent | 11.02.2016 | Fee for grant paid | 11.02.2016 | Fee for publishing/printing paid | 11.02.2016 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP01950251.7 / EP1290149 | Divisional application(s) | EP16163948.9 / EP3093341 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20010950251) is 06.03.2008 | Opposition(s) | 10.01.2017 | No opposition filed within time limit [2017/11] | Fees paid | Renewal fee | 29.06.2010 | Renewal fee patent year 03 | 29.06.2010 | Renewal fee patent year 04 | 29.06.2010 | Renewal fee patent year 05 | 29.06.2010 | Renewal fee patent year 06 | 29.06.2010 | Renewal fee patent year 07 | 29.06.2010 | Renewal fee patent year 08 | 29.06.2010 | Renewal fee patent year 09 | 29.06.2010 | Renewal fee patent year 10 | 25.05.2011 | Renewal fee patent year 11 | 25.05.2012 | Renewal fee patent year 12 | 28.05.2013 | Renewal fee patent year 13 | 27.05.2014 | Renewal fee patent year 14 | 12.05.2015 | Renewal fee patent year 15 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 06.04.2016 | BE | 06.04.2016 | CY | 06.04.2016 | DK | 06.04.2016 | FI | 06.04.2016 | IT | 06.04.2016 | MC | 06.04.2016 | NL | 06.04.2016 | SE | 06.04.2016 | TR | 06.04.2016 | IE | 25.05.2016 | LU | 25.05.2016 | GR | 07.07.2016 | PT | 08.08.2016 | [2018/29] |
Former [2017/38] | AT | 06.04.2016 | |
BE | 06.04.2016 | ||
DK | 06.04.2016 | ||
FI | 06.04.2016 | ||
IT | 06.04.2016 | ||
MC | 06.04.2016 | ||
NL | 06.04.2016 | ||
SE | 06.04.2016 | ||
IE | 25.05.2016 | ||
GR | 07.07.2016 | ||
PT | 08.08.2016 | ||
Former [2017/07] | AT | 06.04.2016 | |
BE | 06.04.2016 | ||
DK | 06.04.2016 | ||
FI | 06.04.2016 | ||
IT | 06.04.2016 | ||
MC | 06.04.2016 | ||
NL | 06.04.2016 | ||
SE | 06.04.2016 | ||
GR | 07.07.2016 | ||
PT | 08.08.2016 | ||
Former [2017/03] | AT | 06.04.2016 | |
BE | 06.04.2016 | ||
FI | 06.04.2016 | ||
IT | 06.04.2016 | ||
NL | 06.04.2016 | ||
SE | 06.04.2016 | ||
GR | 07.07.2016 | ||
PT | 08.08.2016 | ||
Former [2016/52] | AT | 06.04.2016 | |
FI | 06.04.2016 | ||
NL | 06.04.2016 | ||
SE | 06.04.2016 | ||
BE | 31.05.2016 | ||
GR | 07.07.2016 | ||
PT | 08.08.2016 | ||
Former [2016/51] | AT | 06.04.2016 | |
FI | 06.04.2016 | ||
NL | 06.04.2016 | ||
BE | 31.05.2016 | ||
GR | 07.07.2016 | ||
PT | 08.08.2016 | ||
Former [2016/50] | AT | 06.04.2016 | |
FI | 06.04.2016 | ||
NL | 06.04.2016 | ||
BE | 31.05.2016 | ||
Former [2016/49] | FI | 06.04.2016 | |
NL | 06.04.2016 | ||
BE | 31.05.2016 | ||
Former [2016/44] | NL | 06.04.2016 | |
BE | 31.05.2016 | ||
Former [2016/37] | BE | 31.05.2016 | Documents cited: | Search | [I]WO9847912 (LIFE TECHNOLOGIES INC [US]) [I] 1-26 * the whole document *; | [I]JP2000139457 (TOYO BOSEKI) [I] 1-26 * the whole document *; | [A]US5405776 (KOTEWICZ MICHAEL L [US], et al) [A] 1-26 * the whole document *; | [A]WO9823733 (UNIV WASHINGTON [US]) [A] 1-26 * the whole document *; | [E]WO0168895 (INVITROGEN CORP [US]) [E] 1-26 * the whole document * | [I] - GERARD G F ET AL, "REVERSE TRANSCRIPTASE: THE USE OF CLONED MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO SYNTHESIZE DNA FROM RNA", MOLECULAR BIOTECHNOLOGY, HUMANA PRESS, INC, US, (19970101), vol. 8, no. 1, doi:10.1007/BF02762340, ISSN 1073-6085, pages 61 - 77, XP001157038 [I] 1-26 * the whole document * DOI: http://dx.doi.org/10.1007/BF02762340 | [A] - CADWELL R AND JOYCE G ET AL, "Randomization of genes by PCR mutagenesis", PCR METHODS & APPLICATIONS, COLD SPRING HARBOR LABORATORY PRESS, US, (19920101), vol. 2, ISSN 1054-9803, pages 28 - 33, XP002087462 [A] 1-26 * the whole document * | [A] - HALVAS E K ET AL, "Development of an in vivo assay to identify structural determinants in murine leukemia virus reverse transcriptase important for fidelity", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20000101), vol. 74, no. 1, ISSN 0022-538X, pages 312 - 319, XP002232188 [A] 1-26 * the whole document * | [A] - KAUSHIK NEERJA ET AL, "Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (19990302), vol. 38, no. 9, doi:10.1021/BI9824285, ISSN 0006-2960, pages 2617 - 2627, XP002232187 [A] 1-26 * the whole document * DOI: http://dx.doi.org/10.1021/bi9824285 | by applicant | US4663290 | US4889818 | US4965188 | WO9610640 | US5374553 | US5948614 | US6015668 | US5668005 | US6063608 | WO9847912 | US5244797 | US5017492 | US5405776 | US5436149 | US5512462 | WO9206188 | WO9206200 | WO9806736 | US5098893 | US4891319 | US5556771 | WO9915702 | WO9851699 | US4683195 | US4683202 | US5455166 | EP0684315 | US5409818 | EP0329822 | EP0534858 | US4962022 | US5498523 | - LE GRICE, S.F.J. ET AL., EMBO JOURNAL, (1991), vol. 10, page 3905 | - HOSTOMSKY, Z. ET AL., J. VIROL., (1992), vol. 66, page 3179 | - HIZI, A.; JOKLIK, W.K., J. BIOL. CHEM., (1977), vol. 252, page 2281 | - GRANDGENETT, D.P. ET AL., PROC. NAT. ACAD. SCI. USA, (1973), vol. 70, page 230 | - SOLTIS, D.A.; SKALKA, A.M., PROC. NAT. ACAD. SCI. USA, (1988), vol. 85, page 3372 | - ALEXANDER, F. ET AL., J. VIROL., (1987), vol. 61, page 534 | - ANDERSON, D. ET AL., FOCUS, (1995), vol. 17, page 53 | - WERNER S.; WOHRL B.M., EUR. J. BIOCHEM., (2000), vol. 267, pages 4740 - 4744 | - WERNER S.; WOHRL B.M., J. VIROL., (2000), vol. 74, pages 3245 - 3252 | - WERNER S.; WOHRL B.M., J. BIOL. CHEM., (1999), vol. 274, pages 26329 - 26336 | - HERNOV, A.P. ET AL., BIOMED. SCI., (1991), vol. 2, page 49 | - GERARD, G.F. ET AL., FOCUS, (1989), vol. 11, no. 4, page 60 | - GERARD, G.F. ET AL., FOCUS, (1992), vol. 14, no. 3, page 91 | - ECKERT; KUNKEL, NUCL. ACIDS RES., (1990), vol. 18, pages 3739 - 3744 | - BOYER J.C. ET AL., METHODS EIIZYMOL., (1996), vol. 275, page 523 | - MAO ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., (1996), vol. 227, pages 489 - 93 | - CRISTOFARI ET AL., JOUR. BIOL. CHEM, (1999), vol. 274, pages 36643 - 36648 | - MULES ET AL., JOUR. VIROL., (1998), vol. 72, pages 6490 - 6503 | - SAIKI, R.K. ET AL., SCIENCE, (1988), vol. 239, pages 487 - 491 | - THOMPSON, J.D. ET AL., NUCLEIC ACIDS RES., (1994), vol. 22, pages 4673 - 4680 | - N KOTEWICZ, M.L. ET AL., NUCL. ACIDS RES., (1988), vol. 16, page 265 | - GERARD, G.F. ET AL., FOCUS, (1992), vol. 14, no. 5, page 91 | - HOUTS, G.E. ET AL., J. VIROL., (1979), vol. 29, page 517 | - KOTEWICZ, M.L. ET AL., NUCL. ACIDS RES., (1988), vol. 16, page 265 | - SOLTIS, D.A.; SKALKA, A.M., PROC. NATL. ACAD. SCI. USA, (1988), vol. 85, pages 3372 - 3376 | - KENDALL ET AL., J. BACTERIOL., (1987), vol. 169, pages 4177 - 4183 | - JOHN ET AL., RAD. INSEC. DIS., (1986), vol. 8, pages 693 - 704 | - IGAKI, JPN. J. BACTERIOL., (1978), vol. 33, pages 729 - 742 | - DARZINS; CHAKRABARTY, J. BACTERIOL., (1984), vol. 159, pages 9 - 18 | - SHINNICK ET AL., NATURE, (1981), vol. 293, pages 543 - 548 | - GEORGIADIS ET AL., STRUCTURE, (1995), vol. 3, pages 879 - 892 | - JOLIOT ET AL., VIROLOGY, (1993), vol. 195, pages 812 - 819 | - SCHWARTZ ET AL., CELL, (1983), vol. 32, pages 853 - 859 | - WONG-STAAL ET AL., NATURE, (1985), vol. 313, pages 277 - 284 | - GUZMAN ET AL., J. BACTERIOL., (1995), vol. 177, no. 14, pages 4121 - 4130 | - ULMANEN ET AL., J. BACTERIOL, (1985), vol. 162, pages 176 - 182 | - WARD ET AL., MOL. GEN. GENET., (1986), vol. 203, page 468478 | - GLICK, J., IND. MICROBIOL., (1987), vol. 1, pages 277 - 282 | - CENATIEMPTO, Y., BIOCHIMIE, (1986), vol. 68, pages 505 - 516 | - GOTTESMAN, ANN. REV. GENET., (1984), vol. 18, pages 415 - 442 | - GOLD ET AL., ANN. REV. MICROBIOL., (1981), vol. 35, page 365404 | - BARNES, W.M., GENE, (1992), vol. 112, pages 29 - 35 | - LAWYER, F.C. ET AL., PCR METH. APPL., (1993), vol. 2, pages 275 - 287 | - FLAMAN, J.-M. ET AL., NUCL. ACIDS RES., (1994), vol. 22, no. 15, pages 3259 - 3260 | - MANIATIS, T. ET AL., CELL, (1978), vol. 15, pages 687 - 701 | - OKAYAMA, H.; BERG, P., MOL. CELL. BIOL., (1982), vol. 2, pages 161 - 170 | - GUBLER, U.; HOFFMAN, B.J., GENE, (1983), vol. 25, pages 263 - 269 | - KRUG, M.S.; BERGER, S.L., METH. ENZYMOL., (1987), vol. 152, pages 316 - 325 | - WILLIAMS, J.G.K. ET AL., NUCL. ACIDS RES., (1990), vol. 18, no. 22, pages 6531 - 6535 | - WELSH, J.; MCCLELLAND, M., NUCL. ACIDS RES., (1990), vol. 18, no. 24, pages 7213 - 7218 | - CAETANO-ANOLLéS ET AL., BIOLTEEHNOLOGY, (1991), vol. 9, pages 553 - 557 | - HEATH, D.D. ET AL., NUCL. ACIDS RES., (1993), vol. 21, no. 24, pages 5782 - 5785 | - VOS, P. ET AL., NUCL. ACIDS RES., (1995), vol. 23, no. 21, pages 4407 - 4414 | - LIN, J.J.; KUO, J., FOCUS, (1995), vol. 17, no. 2, pages 66 - 70 | - KUNKEL, T.A. ET AL., METHODS ENZYMOL., (1991), vol. 204, page 125 | - PRESTON, B.D. ET AL., SCIENCE, (1988), vol. 242, page 1168 | US20010808124 | US20000189454 | US19970801720 |