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Extract from the Register of European Patents

EP About this file: EP2345745

EP2345745 - Methods and nucleic acids for analyses of colorectal cell proliferative disorders [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.06.2012
Database last updated on 11.09.2024
Most recent event   Tooltip15.06.2012Application deemed to be withdrawnpublished on 18.07.2012  [2012/29]
Applicant(s)For all designated states
Epigenomics AG
IP Department
Kleine Präsidentstrasse 1
10178 Berlin / DE
[N/P]
Former [2011/29]For all designated states
Epigenomics AG
IP Department Kleine Präsidentstrasse 1
10178 Berlin / DE
Inventor(s)01 / Lofton-Day, Cathy
4816 Linden Ave N
Seattle, WA 98103 / US
02 / Model, Fabian
Debenzer Str. 73
12683, Berlin / DE
03 / Sledziewski, Andrew
17736 15th Ave. NW
Shoreline, WA 98177 / US
04 / Rujan, Tamas
Wintererstraße 47a
79104, Freiburg / DE
05 / Lewin, Jörn
Schwartzkopffstr. 10
10115, Berlin / DE
06 / Distler, Jürgen
Herderstr. 24
12163, Berlin / DE
 [2011/29]
Representative(s)Zwicker, Jörk, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2011/47]Zwicker, Jörk, et al
Dr. Volker Vossius
Patent- und Rechtsanwaltskanzlei
Partnerschaft
Geibelstrasse 6
81679 München / DE
Former [2011/46]Vossius, Volker, et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München / DE
Application number, filing date10174719.423.06.2004
[2011/29]
Priority number, dateUS2003060249423.06.2003         Original published format: US 602494
US2003060313823.06.2003         Original published format: US 603138
EP2004009017506.05.2004         Original published format: EP 04090175
EP2004009007227.02.2004         Original published format: EP 04090072
US2003067906203.10.2003         Original published format: US 679062
[2011/29]
Previously filed application, dateWO2004US2033623.06.2004
[2011/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2345745
Date:20.07.2011
Language:EN
[2011/29]
Search report(s)(Supplementary) European search report - dispatched on:EP10.06.2011
ClassificationIPC:C12Q1/68, C07H21/00
[2011/29]
CPC:
C12Q1/6886 (EP,US); C12Q2600/112 (EP,US); C12Q2600/154 (EP,US);
C12Q2600/156 (EP,US); C12Q2600/16 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/29]
TitleGerman:Verfahren und Nukleinsäuren zur Analyse von Störungen der Proliferation kolorektaler Zellen[2011/29]
English:Methods and nucleic acids for analyses of colorectal cell proliferative disorders[2011/29]
French:Procédés et acides nucléiques d'analyse des troubles de prolifération de cellules colorectales[2011/29]
Examination procedure21.01.2012Application deemed to be withdrawn, date of legal effect  [2012/29]
28.02.2012Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2012/29]
Parent application(s)   TooltipEP04777046.6  / EP1636386
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20040777046) is  06.10.2008
Fees paidRenewal fee
31.08.2010Renewal fee patent year 03
31.08.2010Renewal fee patent year 04
31.08.2010Renewal fee patent year 05
31.08.2010Renewal fee patent year 06
31.08.2010Renewal fee patent year 07
21.06.2011Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]WO0224056  (UNIV CASE WESTERN RESERVE [US], et al) [I] 1-10,15-17 * the whole document *;
 [I]WO03014388  (EPIGENOMICS AG [DE], et al) [I] 1-10,15-17 * page 8, line 32 - page 20, line 31 * * page 23, line 1 - page 24, line 8; claims 1-40; table 1 *;
 [X]  - "Homo sapiens cDNA FLJ30489 fis, clone BRAWH2000142, highly similar to Rattus norvegicus vesicular GABA transporter (VGAT) mRNA.", EMBL, (20011031), Database accession no. AK055051, URL: EBI, XP002638259 [X] 11-14 * the whole document *
 [X]  - "Immunostimulatory nucleic acid SEQ ID NO: 260.", Geneseq, (20010612), Database accession no. AAF99133, URL: EBI, XP002638260 [X] 11-14 * the whole document *
 [I]  - TOYOTA M ET AL, "CpG island methylator phenotype in colorectal cancer", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (199907), vol. 96, ISSN 0027-8424, pages 8681 - 8686, XP002307651 [I] 1-10,15-17 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.96.15.8681
 [I]  - RASHID ASIF ET AL, "CpG island methylation in colorectal adenomas", AMERICAN JOURNAL OF PATHOLOGY, (200109), vol. 159, no. 3, ISSN 0002-9440, pages 1129 - 1135, XP002328021 [I] 1-10,15-17 * the whole document *
 [I]  - VAN RIJNSOEVER M ET AL, "Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands.", GUT, (200212), vol. 51, no. 6, ISSN 0017-5749, pages 797 - 802, XP002328020 [I] 1-10,15-17 * the whole document *

DOI:   http://dx.doi.org/10.1136/gut.51.6.797
 [T]  - LOFTON-DAY CATHERINE ET AL, "DNA methylation biomarkers for blood-based colorectal cancer screening", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, (20080201), vol. 54, no. 2, doi:10.1373/CLINCHEM.2007.095992, ISSN 0009-9147, pages 414 - 423, XP009107287 [T] * the whole document *

DOI:   http://dx.doi.org/10.1373/clinchem.2007.095992
by applicantUS5786146
 WO0026401
 WO9500669
 US6251594
 WO9928498
 WO9746705
 WO9515373
 US2003013091
 US6265171
 US6331393
    - LIPSHUTZ, R. J. ET AL., NATURE GENETICS, (1999), vol. 21, pages 20 - 24
    - BOWTELL, D. D. L., NATURE GENETICS, (1999), vol. 21, pages 25 - 32
    - SABBIONI ET AL., MOLECULAR DIAGNOSIS, (2003), vol. 7, pages 201 - 207
    - YOUNG J; BIDEN KG; SIMMS LA; HUGGARD P; KARAMATIC R; EYRE HJ; SUTHERLAND GR; HERATH N; BARKER M; ANDERSON GJ, "HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers", PROC NATL ACAD SCI USA, (2001), vol. 98, pages 265 - 270
    - GONZALGO ET AL., CANCER RESEARCH, (1997), vol. 57, pages 594 - 599
    - EADS ET AL., CANCER RES., (1999), vol. 59, pages 2302 - 2306
    - GONZALGO; JONES, NUCLEIC ACIDS RES., (1997), vol. 25, pages 2529 - 2531
    - HERMAN ET AL., PROC. NATL. ACAD. SCI. USA, (1996), vol. 93, pages 9821 - 9826
    - XIONG; LAIRD, NUCLEIC ACIDS RES., (1997), vol. 25, pages 2532 - 2534
    - TOYOTA ET AL., CANCER RES., (1999), vol. 59, pages 2307 - 12
    - OLEK A ET AL., "A modified and improved method for bisulfite based cytosine methylation analysis", NUCLEIC ACIDS RES., (1996), vol. 24, pages 5064 - 6
    - REIN, T. ET AL., NUCLEIC ACIDS RES., (1998), vol. 26, page 2255
    - ZESCHNIGK M, EUR J HUM GENET., (1997), vol. 5, pages 94 - 98
    - OLEK; WALTER, NAT GENET., (1997), vol. 17, pages 275 - 6
    - GONZALGO; JONES, NUCLEIC ACIDS RES., (1997), vol. 25, pages 2529 - 31
    - XIONG; LAIRD, NUCLEIC ACIDS RES., (1997), vol. 25, pages 2532 - 4
    - GRIGG; CLARK, BIOESSAYS, (1994), vol. 16, pages 431 - 6
    - ZESCHNIGK M, HUM MOL GENET., (1997), vol. 6, pages 387 - 95
    - FEIL R ET AL., NUCLEIC ACIDS RES., (1994), vol. 22, page 695
    - MARTIN V ET AL., GENE, (1995), vol. 157, pages 261 - 4
    - FROMMER ET AL., PROC. NATL. ACAD. SCI. USA, (1992), vol. 89, pages 1827 - 1831
    - SADRI; HORNSBY, NUCL. ACIDS RES., (1996), vol. 24, pages 5058 - 5059
    - BELYAVSKY ET AL., NUCL ACID RES, (1989), vol. 17, pages 2919 - 2932
    - KRUG; BERGER, Methods in Enzymology, ACADEMIC PRESS, (1987), vol. L52, pages 316 - 325
    - Basic and Clinical Immunology, APPLETON & L ANGE, (1991), pages 217 - 262
    - MILSTEIN; KOHLER, NATURE, (1975), vol. 256, pages 495 - 497
    - GULFRE; MILSTEIN, Methods in Enzymology: Immunochemical Techniques, ACADEMIC PRESS, (1981), vol. 73, pages 1 - 46
    - NATURE GENETICS SUPPLEMENT, (199901), vol. 21
    - YU, BIOTECHNIQUES, (1997), vol. 23, pages 714 - 720
    - KARAS; HILLENKAMP, ANAL CHEM., (1988), vol. 60, pages 2299 - 301
    - GUT; BECK, CURRENT INNOVATIONS AND FUTURE TRENDS, (1995), vol. 1, pages 147 - 57
    - GUT; BECK, NUCLEIC ACIDS RES., (1995), vol. 23, pages 1367 - 73
    - HEID ET AL., GENOME RES., (1996), vol. 6, pages 986 - 994
    - SANGER F. ET AL., PROC NATL ACAD SCI USA, (1977), vol. 74, pages 5463 - 5467
    - IRIZARRY RA; HOBBS B; COLLIN F; BEAZER-BARCLAY YD; ANTONELLIS KJ; SCHERF U; SPEED TP, "Exploration, normalization, and summaries of high density oligonucleotide array probe level data", BIOSTATISTICS, (200304), vol. 4, no. 2, pages 249 - 64
    - GAUTIER L; COPE L; BOLSTAD BM; IRIZARRY RA, "affy--analysis of Affymetrix GeneChip data at the probe level", BIOINFORMATICS, (20040212), vol. 20, no. 3, pages 307 - 150
 US20030898743
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.