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Extract from the Register of European Patents

EP About this file: EP2292664

EP2292664 - Multispecific deimmunized CD3-binders [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  11.01.2019
Database last updated on 18.11.2024
FormerThe patent has been granted
Status updated on  26.09.2018
Most recent event   Tooltip24.06.2022Lapse of the patent in a contracting state
New state(s): HU		published on 27.07.2022  [2022/30]
Applicant(s)For all designated states
Amgen Research (Munich) GmbH
Staffelseestrasse 2
81477 München / DE
[2012/34]
Former [2011/10]For all designated states
Micromet AG
Staffelseestrasse 2
81477 München / DE
Inventor(s)01 / Lenkkeri-Schütz, Ulla
Alexander-Pachmann-Str. 31
85716 Unterschleißheim / DE
02 / Kohleisen, Birgit
Flemischweg 38
80689 München / DE
03 / Itin, Christian
Traubingerstr. 18
82340 Feldafing / DE
04 / Hofmeister, Robert
15 Three Ring Road
Scituate, MA 02066 / US
05 / Williams, Stephen
Balvenie House
Alford, Aberdeenshire AB33 8HJ / GB
06 / Hamilton, Anita A.
130 Kings Gate
Aberdeen, AB15 4EQ / GB
07 / Bäuerle, Patrick
Waldpromenade 18c
82131 Gauting / DE
08 / Carr, Francis J.
Birchlea The Holdings
Balmedie, Aberdeenshire, AB23 8XU / GB
 [2016/47]
Former [2011/10]01 / Lenkkeri-Schütz, Ulla
Alexander-Pachmann-Str. 31
85716 Unterschleißheim / DE
02 / Kohleisen, Birgit
Flemischweg 38
80689 München / DE
03 / Itin, Christian
Traubingerstr. 18
82340 Feldafing / DE
04 / Hofmeister, Robert
15 Three Ring Road
Scituate, MA 02066 / US
05 / Williams, Stephen
Balvenie House
Alford, Aberdeenshire AB33 8HJ / GB
06 / Hamilton, Anita A.
130 Kings Gate
Aberdeen, AB15 4EQ / GB
07 / Bäuerle, Patrick
Waldpromenade 18c
82131 Gauting / DE
08 / Carr, Francis J.
Birchlea The Holdings
Balmedie, Aberdeenshire, AB23 8XU / GB
Representative(s)Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
Ganghoferstraße 68 B
80339 München / DE
[N/P]
Former [2016/47]Schiweck, Weinzierl & Koch
European Patent Attorneys
Landsberger Straße 98
80339 München / DE
Former [2011/33]Schiweck, Weinzierl & Koch
European Patent Attorneys Landsberger Straße 98
80339 München / DE
Former [2011/10]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date10177720.915.10.2004
[2011/10]
Priority number, dateEP2003002358116.10.2003         Original published format: EP 03023581
[2011/10]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2292664
Date:09.03.2011
Language:EN
[2011/10]
Type: A3 Search report 
No.:EP2292664
Date:16.03.2011
[2011/11]
Type: B1 Patent specification 
No.:EP2292664
Date:23.11.2016
Language:EN
[2016/47]
Search report(s)(Supplementary) European search report - dispatched on:EP11.02.2011
ClassificationIPC:C07K16/28, A61K39/395, C12N15/13
[2011/10]
CPC:
A61P19/02 (EP); C07K16/2803 (EP,NO,US); C07K16/28 (KR);
C07K16/2896 (NO,US); A61P29/00 (EP); A61P31/04 (EP);
A61P31/12 (EP); A61P31/18 (EP); A61P33/00 (EP);
A61P35/00 (EP); A61P37/00 (EP); A61P37/02 (EP);
A61P37/06 (EP); A61P37/08 (EP); A61P39/00 (EP);
A61P43/00 (EP); C07K16/2809 (EP,NO,US); C07K16/30 (EP,US);
C12N15/11 (KR); C12N15/63 (KR); A61K2039/505 (EP,US);
C07K2317/24 (EP,US); C07K2317/31 (EP,US); C07K2317/567 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/47]
Former [2011/10]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Multispezifische, deimmunsierte CD3-bindende Moleküle[2011/10]
English:Multispecific deimmunized CD3-binders[2011/10]
French:Molécules des-immunisées liant le CD3 multispecifiques[2011/10]
Examination procedure15.09.2011Amendment by applicant (claims and/or description)
15.09.2011Examination requested  [2011/43]
14.11.2011Despatch of a communication from the examining division (Time limit: M04)
13.03.2012Reply to a communication from the examining division
29.11.2013Despatch of a communication from the examining division (Time limit: M04)
09.04.2014Reply to a communication from the examining division
26.08.2015Despatch of a communication from the examining division (Time limit: M06)
03.03.2016Reply to a communication from the examining division
08.04.2016Despatch of a communication from the examining division (Time limit: M01)
20.04.2016Reply to a communication from the examining division
11.05.2016Communication of intention to grant the patent
20.09.2016Fee for grant paid
20.09.2016Fee for publishing/printing paid
20.09.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP04790488.3  / EP1673398
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20040790488) is  22.01.2008
Opposition(s)Opponent(s)01  23.08.2017  29.08.2017  ADMISSIBLE
Janssen Biotech, Inc.
800/850 Ridgeview Drive
Horsham PA 19044-3607 / US
Opponent's representative
Goodfellow, Hugh Robin
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
 [2017/40]
02.10.2017Invitation to proprietor to file observations on the notice of opposition
14.03.2018Reply of patent proprietor to notice(s) of opposition
27.09.2018Despatch of communication that the patent will be revoked
07.10.2018Legal effect of revocation of patent [2019/07]
Fees paidRenewal fee
13.01.2011Renewal fee patent year 03
13.01.2011Renewal fee patent year 04
13.01.2011Renewal fee patent year 05
13.01.2011Renewal fee patent year 06
30.12.2010Renewal fee patent year 07
20.10.2011Renewal fee patent year 08
23.10.2012Renewal fee patent year 09
24.10.2013Renewal fee patent year 10
14.10.2014Renewal fee patent year 11
12.10.2015Renewal fee patent year 12
11.10.2016Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.10.2004
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
TR23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
IE15.10.2017
LU15.10.2017
[2022/30]
Former [2022/26]AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
TR23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
IE15.10.2017
LU15.10.2017
Former [2020/21]AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
IE15.10.2017
LU15.10.2017
Former [2018/45]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
IE15.10.2017
LU15.10.2017
Former [2018/36]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
LU15.10.2017
Former [2018/29]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/52]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/38]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
BG23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/37]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
IT23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
GR24.02.2017
PT23.03.2017
Former [2017/36]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
GR24.02.2017
PT23.03.2017
Former [2017/35]AT23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
GR24.02.2017
PT23.03.2017
Former [2017/31]AT23.11.2016
ES23.11.2016
FI23.11.2016
NL23.11.2016
PL23.11.2016
SE23.11.2016
GR24.02.2017
PT23.03.2017
Documents cited:Search[Y]EP0620276  (CELLTECH LTD [GB]) [Y] 1-38 * page 3, line 29 - line 45 * * page 4, line 49 - line 56 * * table 2 * * figure 5 * * SEQ ID NO:22 *;
 [YD]WO9954440  (DOERKEN BERND [DE], et al) [YD] 1-38 * abstract *;
 [A]WO02066514  (MERCK PATENT GMBH [DE], et al) [A] 1-38 * page 5, line 27 - page 6, line 31 * * page 65, line 1 - page 70, line 7 * * page 71, line 23 - line 32 * * page 72, line 18 - page 74, line 9 *;
 [A]US6491916  (BLUESTONE JEFFREY A [US], et al) [A] 1-38 * column 2, paragraph L * * column 3, line 66 - column 4, line 1 * * column 8, line 47 - column 9, line 21 *;
 [AP]US2004162411  (LANZAVECCHIA ANTONIO [CH]) [AP] 1-38* the whole document *;
 [A]  - MALETZ K ET AL, "Bispecific single-chain antibodies as effective tools for eliminating epithelial cancer cells from human stem cell preparations by redirected cell cytotoxicity", INTERNATIONAL JOURNAL OF CANCER, (20010801), vol. 93, no. 3, ISSN 0020-7136, pages 409 - 416, XP002301955 [A] 1-38 * page 409, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1002/ijc.1348
by applicantUS4361549
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 WO9420627
 WO9429469
 US5580859
 US5589466
 WO9700957
 US5736137
 WO9852976
 WO9925818
 WO9954440
 WO0005268
 WO0034317
 EP1025854
 WO0067795
 WO0147953
 WO0204021
 US2002006404
 WO0212899
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 US6407213
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 WO02069232
 WO02079415
 WO02080987
 WO03004648
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OppositionEP0620276
 WO9852976
 WO9954440
 WO02066514
 US6491916
    - MALETZ et al., "Bispecific single-chain antibodies as effective tools for eliminating epithelial cancer cells from human stem cell preparations by redirected cell cytotoxicity", International Journal of Cancer, (20010800), vol. 93, no. 3, pages 409 - 416, XP002301955

DOI:   http://dx.doi.org/10.1002/ijc.1348
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