EP2305824 - MULTIPLE INDUCIBLE GENE REGULATION SYSTEM [Right-click to bookmark this link] | |||
Former [2011/14] | Multiple inducible gene regulation system | ||
[2017/11] | Status | No opposition filed within time limit Status updated on 13.07.2018 Database last updated on 31.08.2024 | |
Former | The patent has been granted Status updated on 04.08.2017 | ||
Former | Grant of patent is intended Status updated on 27.07.2017 | ||
Former | Examination is in progress Status updated on 23.06.2017 | ||
Former | Grant of patent is intended Status updated on 12.02.2017 | Most recent event Tooltip | 29.05.2020 | Lapse of the patent in a contracting state New state(s): PT | published on 01.07.2020 [2020/27] | Applicant(s) | For all designated states Intrexon Corporation 1750 Kraft Drive, Suite 1400 Blacksburg, VA 24060 / US | [2017/35] |
Former [2017/17] | For all designated states Intrexon Corporation 1750 Kraft Drive, Suite 1400 Blacksburg, VA 26060 / US | ||
Former [2011/14] | For all designated states Intrexon Corporation 1872 Pratt Drive Suite 1400 Blacksburg, Virginia 24060 / US | Inventor(s) | 01 /
DHADIALLA, Tarlochan, Singh 108 Ridge Court Chalfont, PA 18914 / US | 02 /
CRESS, Dean, Ervin 104 Leslie Lane Sounderton, PA 18964 / US | 03 /
CARLSON, Glenn, Richard 305 Britt Road North Wales, PA 19454 / US | 04 /
HORMANN, Robert, Eugene 7413 Richards Road Melrose Park, PA 19027 / US | 05 /
PALLI, Subba, Reddy 832 Garfield Avenue Lansdale, PA 19446 / US | 06 /
KUDLA, Arthur, John 1820 Carles Court Charlottesville, VA 22911 / US | 07 /
HERZIG, Ronald, Phillip, Jr 212 Oak View Road Barboursville, VA 22923 / US | 08 /
PHILIP, Mohan 2565 Holly Knoll Lane Charlottesville, VA 22901 / US | [2017/36] |
Former [2011/14] | 01 /
Dhadialla, Tarlochan, Singh 108 Ridge Court Chalfont, PA 18914 / US | ||
02 /
Cress, Dean, Ervin 104 Leslie Lane Sounderton, PA 18964 / US | |||
03 /
Carlson, Glenn, Richard 305 Britt Road North Wales, PA 19454 / US | |||
04 /
Hormann, Robert, Eugene 7413 Richards Road Melrose Park, PA 19027 / US | |||
05 /
Palli, Subba, Reddy 832 Garfield Avenue Lansdale, PA 19446 / US | |||
06 /
Kudla, Arthur, John 1820 Carles Court Charlottesville, VA 22911 / US | |||
07 /
Herzig, Ronald, Phillip, Jr 212 Oak View Road Barboursville, VA 22923 / US | |||
08 /
Philip, Mohan 2565 Holly Knoll Lane Charlottesville, VA 22901 / US | Representative(s) | D Young & Co LLP 3 Noble Street London EC2V 7BQ / GB | [N/P] |
Former [2017/36] | D Young & Co LLP 120 Holborn London EC1N 2DY / GB | ||
Former [2011/14] | Harding, Charles Thomas D Young & Co LLP 120 Holborn London EC1N 2DY / GB | Application number, filing date | 10180377.3 | 28.09.2001 | [2011/14] | Priority number, date | US20000237446P | 03.10.2000 Original published format: US 237446 P | US20010965697 | 27.09.2001 Original published format: US 965697 | [2011/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2305824 | Date: | 06.04.2011 | Language: | EN | [2011/14] | Type: | B1 Patent specification | No.: | EP2305824 | Date: | 06.09.2017 | Language: | EN | [2017/36] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.02.2011 | Classification | IPC: | C12N15/86, C12N15/82, C07K14/705, C07K14/72, C12N15/10, A01K67/027 | [2011/14] | CPC: |
C12N15/635 (EP,US);
A61P1/00 (EP);
C07K14/721 (EP,US);
C12N15/70 (US);
C12N15/74 (US);
C12N15/80 (US);
C12N15/81 (US);
C12N15/8217 (EP,US);
C12N15/8238 (EP,US);
C12N15/8241 (US);
C12N15/85 (US);
C12N15/861 (US);
G01N33/6845 (US);
A01K2217/05 (EP,US);
A61K48/00 (US);
C07K2319/00 (EP,US)
(-)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2017/36] |
Former [2011/14] | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR | Title | German: | MEHRFACH-INDUZIERBARES GENREGULIERUNGSSYSTEM | [2017/11] | English: | MULTIPLE INDUCIBLE GENE REGULATION SYSTEM | [2017/11] | French: | SYSTÈME DE RÉGULATION DE PLUSIEURS GÈNES INDUCTIBLES | [2017/11] |
Former [2011/14] | Mehrfach-induzierbares Genregulierungssystem | ||
Former [2011/14] | Multiple inducible gene regulation system | ||
Former [2011/14] | Système de régulation de plusieurs gènes inductibles | Examination procedure | 04.10.2011 | Amendment by applicant (claims and/or description) | 04.10.2011 | Examination requested [2011/46] | 05.07.2012 | Despatch of a communication from the examining division (Time limit: M06) | 11.01.2013 | Reply to a communication from the examining division | 16.09.2013 | Despatch of a communication from the examining division (Time limit: M06) | 06.03.2014 | Reply to a communication from the examining division | 25.06.2014 | Despatch of a communication from the examining division (Time limit: M04) | 13.10.2014 | Reply to a communication from the examining division | 20.01.2015 | Despatch of a communication from the examining division (Time limit: M04) | 27.05.2015 | Reply to a communication from the examining division | 25.09.2015 | Despatch of a communication from the examining division (Time limit: M04) | 02.02.2016 | Reply to a communication from the examining division | 03.06.2016 | Despatch of a communication from the examining division (Time limit: M04) | 29.09.2016 | Reply to a communication from the examining division | 13.02.2017 | Communication of intention to grant the patent | 16.06.2017 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 16.06.2017 | Fee for grant paid | 16.06.2017 | Fee for publishing/printing paid | 26.07.2017 | Information about intention to grant a patent | 26.07.2017 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP01975606.3 / EP1334200 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20010975606) is 13.04.2006 | Opposition(s) | 07.06.2018 | No opposition filed within time limit [2018/33] | Fees paid | Renewal fee | 07.12.2010 | Renewal fee patent year 03 | 07.12.2010 | Renewal fee patent year 04 | 07.12.2010 | Renewal fee patent year 05 | 07.12.2010 | Renewal fee patent year 06 | 07.12.2010 | Renewal fee patent year 07 | 07.12.2010 | Renewal fee patent year 08 | 07.12.2010 | Renewal fee patent year 09 | 07.12.2010 | Renewal fee patent year 10 | 08.09.2011 | Renewal fee patent year 11 | 25.09.2012 | Renewal fee patent year 12 | 27.09.2013 | Renewal fee patent year 13 | 29.09.2014 | Renewal fee patent year 14 | 28.09.2015 | Renewal fee patent year 15 | 27.09.2016 | Renewal fee patent year 16 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 06.09.2017 | CY | 06.09.2017 | DK | 06.09.2017 | ES | 06.09.2017 | FI | 06.09.2017 | IT | 06.09.2017 | MC | 06.09.2017 | NL | 06.09.2017 | PT | 06.09.2017 | SE | 06.09.2017 | TR | 06.09.2017 | IE | 28.09.2017 | LU | 28.09.2017 | BE | 30.09.2017 | CH | 30.09.2017 | LI | 30.09.2017 | FR | 06.11.2017 | GB | 06.12.2017 | GR | 07.12.2017 | DE | 04.04.2018 | [2020/27] |
Former [2020/16] | AT | 06.09.2017 | |
CY | 06.09.2017 | ||
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
TR | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
FR | 06.11.2017 | ||
GB | 06.12.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2019/46] | AT | 06.09.2017 | |
CY | 06.09.2017 | ||
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
FR | 06.11.2017 | ||
GB | 06.12.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2018/50] | AT | 06.09.2017 | |
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
FR | 06.11.2017 | ||
GB | 06.12.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2018/49] | AT | 06.09.2017 | |
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
FR | 06.11.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2018/36] | AT | 06.09.2017 | |
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
BE | 30.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2018/33] | AT | 06.09.2017 | |
DK | 06.09.2017 | ||
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
MC | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
IE | 28.09.2017 | ||
LU | 28.09.2017 | ||
CH | 30.09.2017 | ||
LI | 30.09.2017 | ||
GR | 07.12.2017 | ||
DE | 04.04.2018 | ||
Former [2018/24] | AT | 06.09.2017 | |
ES | 06.09.2017 | ||
FI | 06.09.2017 | ||
IT | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
GR | 07.12.2017 | ||
Former [2018/15] | ES | 06.09.2017 | |
FI | 06.09.2017 | ||
NL | 06.09.2017 | ||
SE | 06.09.2017 | ||
GR | 07.12.2017 | ||
Former [2018/12] | ES | 06.09.2017 | |
FI | 06.09.2017 | ||
SE | 06.09.2017 | ||
GR | 07.12.2017 | ||
Former [2018/09] | FI | 06.09.2017 | |
SE | 06.09.2017 | ||
Former [2018/08] | FI | 06.09.2017 | Documents cited: | Search | [A]WO9627673 (CIBA GEIGY AG [CH]) [A] 1-15 * figure 3; example 21; table 7 *; | [X]WO9902683 (SALK INST FOR BIOLOGICAL STUDI [US], et al) [X] 1-15 * figures 1C,2E; examples 2,3,17 *; | [XP]WO0170816 (ROHM & HAAS [US], et al) [XP] 1-15* the whole document *; | [X] - MORADOPOUR DARIUS ET AL, "Independent regulation of two separate gene activities in a continuous human cell line.", BIOLOGICAL CHEMISTRY, (199808), vol. 379, no. 8-9, ISSN 1431-6730, pages 1189 - 1191, XP001070604 [X] 1-15 * figures 1,2 * | [A] - MARTINEZ A ET AL, "Creation of ecdysone receptor chimeras in plants for controlled regulation of gene expression.", MOLECULAR AND GENERAL GENETICS, (199904), vol. 261, no. 3, ISSN 0026-8925, pages 546 - 552, XP001069830 [A] 1-15 * figures 3,5 * DOI: http://dx.doi.org/10.1007/s004380050999 | [A] - KOTHAPALLI R ET AL, "CLONING AND DEVELOPMENTAL EXPRESSION OF THE ECDYSONE RECEPTOR GENE FROM THE SPRUCE BUDWORM, CHORISTONEURA FUMIFERANAN", DEVELOPMENTAL GENETICS, NEW-YORK, NY, US, (1995), vol. 17, no. 4, ISSN 0192-253X, pages 319 - 330, XP000577688 [A] 1-15 * figure 1 * DOI: http://dx.doi.org/10.1002/dvg.1020170405 | [A] - NO D ET AL, "ECDYSONE-INDUCIBLE GENE EXPRESSION IN MAMMALIAN CELLS AND TRANSGENIC MICE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (19960416), vol. 93, no. 8, ISSN 0027-8424, pages 3346 - 3351, XP002036328 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.93.8.3346 | by applicant | EP0234994 | CA2012311 | US4981784 | US4985461 | EP0461809 | US5117057 | US5225443 | US5283173 | US5378726 | WO9518863 | WO9521931 | US5459127 | WO9617823 | US5530028 | US5530021 | WO9625508 | US5580859 | US5589466 | WO9738117 | US5693622 | WO9902683 | US5880333 | WO9936520 | WO9958155 | US6013836 | US6265173 | - WUM ET AL., PROC. NATL. ACAD. SCI. USA, (1986), vol. 83, pages 5414 - 5418 | - AMHEITER ET AL., CELL, (1990), vol. 62, pages 51 - 61 | - FILMUS ET AL., NUCLEIC ACIDS RESEARCH, (1992), vol. 20, pages 27550 - 27560 | - SPENCER ET AL., SCIENCE, (1993), vol. 262, pages 1019 - 24 | - BELSHAW ET AL., PROC NATL ACAD SCI USA, (1996), vol. 93, pages 4604 - 7 | - KOELLE ET AL., CELL, (1991), vol. 67, pages 59 - 77 | - LAUDET ET AL., "A Unified Nomenclature System for the Nuclear Receptor Subfamily", CELL, (1999), vol. 97, doi:doi:10.1016/S0092-8674(00)80726-6, pages 161 - 163, XP002405278 DOI: http://dx.doi.org/10.1016/S0092-8674(00)80726-6 | - RIDDIFORD ET AL., VITAM HORM., (2000), vol. 60, pages 1 - 73 | - CHRISTOPHERSON ET AL., PNAS, (1992), vol. 89, no. 14, pages 6314 - 8 | - NO ET AL., PNAS, (1996), vol. 98, no. 8, pages 3346 - 51 | - SUHR ET AL., PNAS, (1998), vol. 95, pages 7999 - 8004 | - WU ET AL., J. BIOL. CHEM., (1992), vol. 267, pages 963 - 967 | - WU; WU, J. BIOL. CHEM., (1988), vol. 263, pages 14621 - 14624 | - FELGNER ET AL., PNAS, (1987), vol. 84, page 7413 | - MACKEY ET AL., PROC. NATL. ACAD. SCI. U.S.A., (1988), vol. 85, pages 8027 - 8031 | - ULMER ET AL., SCIENCE, (1993), vol. 259, pages 1745 - 1748 | - FEIGNER; RINGOLD, SCIENCE, (1989), vol. 337, pages 387 - 388 | - CURIEL ET AL., HUM. GENE THER., (1992), vol. 3, pages 147 - 154 | - WU; WU, J. BIOL. CHEM., (1987), vol. 262, pages 4429 - 4432 | - CHERBAS L., GENES DEV., (1991), vol. 5, pages 120 - 131 | - D'AVINO PP., MOL. CELL. ENDOCRINOL, (1995), vol. 113, pages 1 - 9 | - ANTONIEWSKI C., MOL. CELL BIOL., (1994), vol. 14, pages 4465 - 4474 | - REECK ET AL., CELL, (1987), vol. 50, page 667 | - ALTSCHUL, S. F. ET AL., J MOL. BIOL., (1993), vol. 215, pages 403 - 410 | - HIGGINS; SHARP, CABIOS, (1989), vol. 5, pages 151 - 153 | - ALTSCHUL ET AL., J. MOL. BIOL., (1990), vol. 215, pages 403 - 410 | - SADOWSKI ET AL., NATURE, (1988), vol. 335, pages 563 - 564 | - BRENT; PTASHNE, CELL, (1985), vol. 43, pages 729 - 736 | - YAO ET AL., NATURE, (1993), vol. 366, pages 476 - 479 | - YAO ET AL., CELL, (1992), vol. 71, pages 63 - 72 | - GLASS ET AL., CURR. OPIN. CELL BIOL., (1997), vol. 9, pages 222 - 232 | - HORWITZ ET AL., MOL ENDOCRINOL., (1996), vol. 10, pages 1167 - 1177 | - EVANS, SCIENCE, (1988), vol. 240, pages 889 - 895 | - KOTHAPALLI ET AL., DEV GENET, (1995), vol. 17, pages 319 - 30 | - MOUILLET ET AL., EUR. J. BIOCHEM., (1997), vol. 248, pages 856 - 863 | - FUJIWARA ET AL., INSECT BIOCHEM. MOLEC. BIOL., (1995), vol. 25, pages 845 - 856 | - MARTINEZ ET AL., INSECT BIOCHEM MOL BIOL., (1999), vol. 29, pages 915 - 30 | - IMHOF ET AL., INSECT BIOCHEM. MOLEC. BIOL., (1993), vol. 23, pages 115 - 124 | - SWEVERS ET AL., INSECT BIOCHEM. MOLEC. BIOL., (1995), vol. 25, pages 857 - 866 | - CHO ET AL., INSECT BIOCHEM. MOLEC. BIOL., (1995), vol. 25, pages 19 - 27 | - HANNAN; HILL, INSECT BIOCHEM. MOLEC. BIOL., (1997), vol. 27, pages 479 - 488 | - VERRAS ET AL., EUR J BIOCHEM., (1999), vol. 265, pages 798 - 808 | - SALEH ET AL., MOL CELL ENDOCRINOL., (1998), vol. 143, pages 91 - 9 | - CHUNG ET AL., MOL CELL ENDOCRINOL, (1998), vol. 139, pages 209 - 27 | - GUO ET AL., INSECT BIOCHEM. MOLEC. BIOL., (1997), vol. 27, pages 945 - 962 | - DHADIALLA ET AL., ANNU REV ENTOMOL, (1998), vol. 43, pages 545 - 69 | - CHANG, C. C. ET AL., NAT BIOTECHNOL, (1999), vol. 17, no. 8, pages 793 - 7 | - STEMMER, W. P., PROC NATL ACAD SCI USA, (1994), vol. 91, no. 22, pages 10747 - 51 | - MICHNICK, S. W.; ARNOLD, F. H., NAT BIOTECHNOL, (1999), vol. 17, no. 12, pages 1159 - 60 | - OSTERMEIER, M. ET AL., NATBIOTECHNOL, (1999), vol. 17, no. 12, pages 1205 - 9 | - HUTCHINSON, C. ET AL., J. BIOL. CHEM., (1978), vol. 253, page 6551 | - ZOLLER; SMITH, DNA, (1984), vol. 3, pages 479 - 488 | - OLIPHANT ET AL., GENE, (1986), vol. 44, page 177 | - HUTCHINSON ET AL., PROC. NATL. ACAD. SCI. U.S.A., (1986), vol. 83, page 710 | - "Using PCR to Engineer DNA", HIGUCHI, PCR Technology: Principles andApplications for DNA Amplification, STOCKTON PRESS, (1989), pages 61 - 70 | - D.N. GLOVER, DNA Cloning: A Practical Approach, (1985), vol. I, II | - TAYLOR ET AL., NUCLEIC ACIDS RES., (1985), vol. 13, pages 8749 - 8764 | - SAIKI RK. ET AL., SCIENCE, (1985), vol. 230, pages 1350 - 1354 | - MULLIS K.B.; FALOONA F.A., METH. ENZYM., (1987), vol. 155, pages 335 - 350 | - SANGER ET AL., PROC. NATL. ACAD. SCI. USA, (1977), vol. 74, pages 5463 - 5467 | WO1996EP00686 | WO2001US09050 | US20010294814 | US20010294819 | WO2001US19050 |