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Extract from the Register of European Patents

EP About this file: EP2348043

EP2348043 - APO-2 ligand variants and uses thereof [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.12.2013
Database last updated on 02.11.2024
Most recent event   Tooltip06.12.2013Application deemed to be withdrawnpublished on 08.01.2014  [2014/02]
Applicant(s)For all designated states
Genentech, Inc.
1 DNA Way
South San Francisco, CA 94080-4990 / US
[N/P]
Former [2011/30]For all designated states
Genentech, Inc.
1 DNA Way
South San Francisco CA 94080-4990 / US
Inventor(s)01 / Kelly, Robert F.
1029 San Felipe Avenue
San Bruno, CA CA 94066 / US
02 / Lindstrom, Stephanie H.
196 Rock Harbour Lane
Foster City, CA CA 94404 / US
 [2011/30]
Representative(s)Kiddle, Simon John, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2011/30]Kiddle, Simon John, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date10183325.901.10.2002
[2011/30]
Priority number, dateUS20010326622P02.10.2001         Original published format: US 326622 P
[2011/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2348043
Date:27.07.2011
Language:EN
[2011/30]
Search report(s)(Supplementary) European search report - dispatched on:EP21.06.2011
ClassificationIPC:C07K14/52, A61K38/19, C07H21/04, C12N15/63, C12N1/21, C12N1/11, C12N5/16, C12N15/12, C07K14/705
[2011/30]
CPC:
C07K14/70575 (EP,US); C07K14/525 (US); A61P19/02 (EP);
A61P25/00 (EP); A61P29/00 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P37/00 (EP);
A61P37/02 (EP); A61P37/06 (EP); A61P43/00 (EP);
A61P9/00 (EP); A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2011/30]
TitleGerman:APO-2-Ligandvarianten und Verwendungen dafür[2011/30]
English:APO-2 ligand variants and uses thereof[2011/30]
French:Variantes du ligand APO-2 et leurs utilisations[2011/30]
Examination procedure19.01.2012Examination requested  [2012/09]
22.05.2012Amendment by applicant (claims and/or description)
18.01.2013Despatch of a communication from the examining division (Time limit: M06)
30.07.2013Application deemed to be withdrawn, date of legal effect  [2014/02]
30.08.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2014/02]
Parent application(s)   TooltipEP02766436.6  / EP1501866
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20020766436) is  21.02.2008
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
22.05.2012Request for further processing filed
22.05.2012Full payment received (date of receipt of payment)
Request granted
12.06.2012Decision despatched
Fees paidRenewal fee
12.11.2010Renewal fee patent year 03
12.11.2010Renewal fee patent year 04
12.11.2010Renewal fee patent year 05
12.11.2010Renewal fee patent year 06
12.11.2010Renewal fee patent year 07
12.11.2010Renewal fee patent year 08
27.10.2010Renewal fee patent year 09
11.10.2011Renewal fee patent year 10
11.10.2012Renewal fee patent year 11
07.10.2013Renewal fee patent year 12
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]WO0100832  (GENENTECH INC [US]) [Y] 1-16 * pages 19, 22; claims 6, 13, 36; table I *;
 [Y]  - WILEY S R ET AL, "IDENTIFICATION AND CHARACTERIZATION OF A NEW MEMBER OF THE TNF FAMILY THAT INDUCES APOPTOSIS", IMMUNITY, CELL PRESS, US, (19951201), vol. 3, no. 6, ISSN 1074-7613, pages 673 - 682, XP000672297 [Y] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1016/1074-7613(95)90057-8
    [ ] - UniProt, (19961001), Database accession no. P50591, URL: EBI [ ] * abstract *
 [Y]  - PITTI R M ET AL, "INDUCTION OF APOPTOSIS BY APO-2 LIGAND, A NEW MEMBER OF THE TUMOR NECROSIS FACTOR CYTOKINE FAMILY", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19960531), vol. 271, no. 22, ISSN 0021-9258, pages 12687 - 12690, XP002031265 [Y] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.271.22.12687
 [A]  - VERONESE F M, "Peptide and protein PEGylation - a review of problems and solutions", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, (20010301), vol. 22, no. 5, ISSN 0142-9612, pages 405 - 417, XP004227886 [A] 1-16

DOI:   http://dx.doi.org/10.1016/S0142-9612(00)00193-9
 [A]  - FRANCIS G E ET AL, "PEGYLATION OF CYTOKINES AND OTHER THERAPEUTIC PROTEINS AND PEPTIDES: THE IMPORTANCE OF BIOLOGICAL OPTIMISATION OF COUPLING TECHNIQUES", INTERNATIONAL JOURNAL OF HEMATOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL, (199807), vol. 68, no. 1, ISSN 0925-5710, pages 1 - 18, XP000938448 [A] 1-16

DOI:   http://dx.doi.org/10.1016/S0925-5710(98)00039-5
 [T]  - KELLEY ROBERT F ET AL, "Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. 21 JAN 2005, (20050121), vol. 280, no. 3, ISSN 0021-9258, pages 2205 - 2212, XP002345722

DOI:   http://dx.doi.org/10.1074/jbc.M410660200
by applicantUS3773919
 US4179337
 EP0058481
 US4399216
 EP0117060
 EP0117058
 EP0133988
 US4657760
 EP0257956
 DD266710
 WO8905859
 US4935465
 WO9100358
 EP0417563
 WO9203478
 WO9217200
 US5166322
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 US5364934
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 WO9725428
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 EP0870827
 WO9846751
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 US5849535
 WO9858062
 WO9902653
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 WO9910484
 WO9911791
 WO9936535
 WO0100832
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 US6245901
 US6284236
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