| EP2338995 - Interfering RNA duplex having blunt-ends and 3'-modifications [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 14.12.2012 Database last updated on 11.04.2026 | Most recent event Tooltip | 14.12.2012 | Application deemed to be withdrawn | published on 16.01.2013 [2013/03] | Applicant(s) | For:BE
BG
CH
CY
CZ
DE
DK
EE
ES
FI
FR
GB
GR
HU
IE
IT
LI
LU
MC
NL
PL
PT
RO
SE
SI
SK
TR
Novartis AG Lichtstrasse 35 4056 Basel / CH | For:AT
Novartis Pharma GmbH Brunner Strasse 59 1230 Wien / AT | [2011/26] | Inventor(s) | 01 /
Weiler, Jan Kandelstrasse 4 79541, Lörrach-Haagen / DE | 02 /
Hall, Jonathan Ramstelweg 19 4143, Dornach / CH | 03 /
Bologna, Jean-Charles 10, rue du Grand-Pont 1950, Sion / CH | 04 /
Natt, François Jean-Charles Traugott Meyer-Strasse 5 4147, Aesch / CH | 05 /
Häner, Robert Scheuermattweg 23 3043, Uettligen / CH | [2011/26] | Representative(s) | Kassow, Anders Novartis Pharma AG Patent Department 4002 Basel / CH | [N/P] |
| Former [2011/26] | Kassow, Anders Novartis Pharma AG Patent Department 4002 Basel / CH | Application number, filing date | 10184568.3 | 27.08.2004 | [2011/26] | Priority number, date | US20030498514P | 28.08.2003 Original published format: US 498514 P | [2011/26] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2338995 | Date: | 29.06.2011 | Language: | EN | [2011/26] | Type: | A3 Search report | No.: | EP2338995 | Date: | 11.01.2012 | Language: | EN | [2012/02] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 08.12.2011 | Classification | IPC: | C12N15/11, A61K48/00 | [2011/26] | CPC: |
C12N15/111 (EP,US);
C12N15/11 (KR);
A61K48/00 (KR);
A61P31/00 (EP);
A61P31/04 (EP);
A61P31/12 (EP);
A61P35/00 (EP);
A61P43/00 (EP);
C12N2310/14 (EP,US);
C12N2310/311 (EP,US);
C12N2310/315 (EP,US);
C12N2310/321 (EP,US);
C12N2310/322 (EP,US);
C12N2310/332 (EP,US);
C12N2320/51 (EP,US);
C12N2330/30 (EP,US)
(-)
| C-Set: |
C12N2310/321, C12N2310/3525 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2011/26] | Extension states | HR | 11.07.2012 | LT | 11.07.2012 | LV | 11.07.2012 | Title | German: | Interfering RNA Duplex umfassend glatte Ende und 3'-Modifizierungen | [2011/26] | English: | Interfering RNA duplex having blunt-ends and 3'-modifications | [2011/26] | French: | Double hélice d'ARN d'interférence possédant des extrémités franches et des modifications en 3' | [2011/26] | Examination procedure | 11.07.2012 | Examination requested [2012/34] | 12.07.2012 | Application deemed to be withdrawn, date of legal effect [2013/03] | 21.08.2012 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time [2013/03] | Parent application(s) Tooltip | EP04764573.4 / EP1660657 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20040764573) is 19.01.2010 | Fees paid | Renewal fee | 31.01.2011 | Renewal fee patent year 03 | 31.01.2011 | Renewal fee patent year 04 | 31.01.2011 | Renewal fee patent year 05 | 31.01.2011 | Renewal fee patent year 06 | 31.01.2011 | Renewal fee patent year 07 | 11.08.2011 | Renewal fee patent year 08 | 10.08.2012 | Renewal fee patent year 09 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y] WO02096927 (RIBOZYME PHARM INC et al.) | [AP] EP1389637 (ATUGEN AG et al.) | [AP] WO2004015107 (ATUGEN AG et al.) | [AP] WO03070918 (RIBOZYME PHARM INC et al.) | [Y] WO2004092383 (SIRNA THERAPEUTICS INC et al.) | [A] WO2004090105 (DHARMACON INC et al.) | [Y] CZAUDERNA F ET AL: "Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 31, no. 11, 1 June 2003 (2003-06-01), pages 2705 - 2716, XP002270732, ISSN: 0305-1048 DOI: http://dx.doi.org/10.1093/nar/gkg393 | [A] HAMADA M ET AL: "EFFECTS OF RNA INTERFERENCE IN GENE EXPRESSION (RNAI) IN CULTURED MAMMALAIN CELLS OF MISMATCHES AND THE INTRODUCTION OF CHEMICAL MODIFICATIONS AT THE 3'-ENDS OF SIRNAS", ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, MARY ANN LIEBERT, INC., NEW YORK, US, vol. 12, no. 5, October 2002 (2002-10-01), pages 301 - 309, XP009006637, ISSN: 1087-2906 DOI: http://dx.doi.org/10.1089/108729002761381285 | [Y] SCHWARZ D S ET AL: "EVIDENCE THAT SIRNAS FUNCTION AS GUIDES, NOT PRIMERS, IN THE DROSOPHILA AND HUMAN RNAI PATHWAYS", MOLECULAR CELL, CELL PRESS, CAMBRIDGE, MA, US, vol. 10, no. 3, 1 September 2002 (2002-09-01), pages 537 - 548, XP009019083, ISSN: 1097-2765, DOI: 10.1016/S1097-2765(02)00651-2 DOI: http://dx.doi.org/10.1016/S1097-2765(02)00651-2 | by applicant | ELBASHIR ET AL., METHODS, vol. 26, 2002, pages 199 - 213 | GRIBSKOV; DEVEREUX: "Sequence Analysis Primer", 1991, STOCKTON PRESS | ELBASHIR S.M. ET AL., EMBO J., vol. 20, 2001, pages 6877 - 6888 | MARTIN ET AL., HELV. CHIM. ACTA, vol. 78, 1995, pages 486 - 504 | HEMMINGS ET AL., NAR, vol. 31, 2003, pages 2117 - 2126 | DORN ET AL., ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, vol. 11, 2001, pages 165 - 174 |