Extract from the Register of European Patents

EP Citations: EP2368877

Cited inSearch
Type:Patent literature
Publication No.:JPH09124691  [I]
 (GREEN CROSS CORP et al.)
Type:Patent literature
Publication No.:US5371072  [I]
 (WEBB THOMAS R et al.)
Type:Patent literature
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Type:Patent literature
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Type:Patent literature
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Type:Patent literature
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 (BOEHRINGER INGELHEIM CA LTD et al.)
Type:Patent literature
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 (BOEHRINGER INGELHEIM CA LTD et al.)
Type:Patent literature
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 (VERTEX PHARMA et al.)
Type:Patent literature
Publication No.:WO9907734  [I]
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Cited inby applicant
Type:Patent literature
Publication No.:WO0009558  
Type:Patent literature
Publication No.:WO0009543  
Type:Patent literature
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Type:Patent literature
Publication No.:WO9907733  
Type:Patent literature
Publication No.:WO9907734  
Type:Patent literature
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Type:Patent literature
Publication No.:WO9846630  
Type:Patent literature
Publication No.:WO9817679  
Type:Patent literature
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Type:Patent literature
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Type:Patent literature
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Type:Non-patent literature
Publication information:  A. ALBERTI ET AL.: "Natural History of Hepatitis C", J. HEPATOLOGY, vol. 31, no. 1, 1999, pages 17 - 24
Type:Non-patent literature
Publication information:  M.J. ALTER: "Hepatitis C Virus Infection in the United States", J. HEPATOLOSV., vol. 31, no. 1, 1999, pages 88 - 91
Type:Non-patent literature
Publication information:  D. LAVANCHY: "Global Surveillance and Control of Hepatitis C", J. VIRAL HEPATITIS, vol. 6, 1999, pages 35 - 47
Type:Non-patent literature
Publication information:  Q.-L. CHOO ET AL.: "Genetic Organization and Diversity of the Hepatitis C Virus", PROC. NATL. ACAD. SCI. USA, vol. 88, 1991, pages 2451 - 2455
Type:Non-patent literature
Publication information:  N. KATO ET AL.: "Molecular Cloning of the Human Hepatitis C Virus Genome From Japanese Patients with Non-A, Non-B Hepatitis", PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 9524 - 9528
Type:Non-patent literature
Publication information:  A. TAKAMIZAWA ET AL.: "Structure and Organization of the Hepatitis C Virus Genome Isolated From Human Carriers", J. VIROL., vol. 65, 1991, pages 1105 - 1113
Type:Non-patent literature
Publication information:  R. BARTENSCHLAGER ET AL.: "Nonstructural Protein 3 of the Hepatitis C Virus Encodes a Serine-Type Proteinase Required for Cleavage at the NS3/4 and NS4/5 Junctions", J. VIROL., vol. 67, 1993, pages 3835 - 3844
Type:Non-patent literature
Publication information:  A. GRAKOUI ET AL.: "Characterization of the Hepatitis C Virus-Encoded Serine Proteinase: Determination of Proteinase-Dependent Polyprotein Cleavage Sites", J. VIROL., vol. 67, 1993, pages 2832 - 2843
Type:Non-patent literature
Publication information:  A. GRAKOUI ET AL.: "Expression and Identification of Hepatitis C Virus Polyprotein Cleavage Products", J. VIROL., vol. 67, 1993, pages 1385 - 1395
Type:Non-patent literature
Publication information:  L. TOMEI ET AL.: "NS3 is a serine protease required for processing of hepatitis C virus polyprotein", J. VIROL., vol. 67, 1993, pages 4017 - 4026
Type:Non-patent literature
Publication information:  C. LIN ET AL.: "Hepatitis C Virus NS3 Serine Proteinase: Trans-Cleavage Requirements and Processing Kinetics", J. VIROL., vol. 68, 1994, pages 8147 - 8157
Type:Non-patent literature
Publication information:  T.J. CHAMBERS ET AL.: "Evidence that the N-terminal Domain of Nonstructural Protein NS3 From Yellow Fever Virus is a Serine Protease Responsible for Site-Specific Cleavages in the Viral Polyprotein", PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 8898 - 8902
Type:Non-patent literature
Publication information:  C.M. RICE ET AL.: "Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3'-nontranslated region are essential for virus replication in vivo.", J. VIROL., vol. 74, no. 4, 2000, pages 2046 - 51
Type:Non-patent literature
Publication information:  M. LLINS-BRUNET ET AL., BIOORG. MED. CHEM. LETT., vol. 8, 1998, pages 1713 - 1718
Type:Non-patent literature
Publication information:  W. HAN ET AL., BIOORG. MED. CHEM. LETT., vol. 10, 2000, pages 711 - 713
Type:Non-patent literature
Publication information:  R. DUNSDON ET AL., BIOORG. MED. CHEM. LETT., vol. 10, 2000, pages 1571 - 1579
Type:Non-patent literature
Publication information:  M. LLINAS-BRUNET ET AL., BIOORG. MED. CHEM. LETT., vol. 10, 2000, pages 2267 - 2270
Type:Non-patent literature
Publication information:  S. LAPLANTE ET AL., BIOORG. MED. CHEM. LETT., vol. 10, 2000, pages 2271 - 2274
Type:Non-patent literature
Publication information:  M.A. WALKER: "Hepatitis C Virus: an Overview of Current Approaches and Progress", DDT, vol. 4, 1999, pages 518 - 529
Type:Non-patent literature
Publication information:  D. MORADPOUR ET AL.: "Current and Evolving Therapies for Hepatitis C", EUR. J. GASTROENTEROL. HEPATOL., vol. 11, 1999, pages 1199 - 1202
Type:Non-patent literature
Publication information:  H.L.A. JANSSEN ET AL.: "Suicide Associated with Alfa-Interferon Therapy for Chronic Viral Hepatitis", J. HEPATOL., vol. 21, 1994, pages 241 - 243
Type:Non-patent literature
Publication information:  P.F. RENAULT ET AL.: "Side effects of alpha interferon", SEMINARS IN LIVER DISEASE, vol. 9, 1989, pages 273 - 277
Type:Non-patent literature
Publication information:  0. WEILAND: "Interferon Therapy in Chronic Hepatitis C Virus Infection", FEMS MICROBIOL. REV., vol. 14, 1994, pages 279 - 288
Type:Non-patent literature
Publication information:  GRECO; PARK; RUSTOM: "Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-13-D-Arabinofuranosylcytosine", CANCER RESEARCFI, vol. 50, 1990, pages 5318 - 5327
Type:Non-patent literature
Publication information:  LIPINSKI: "Bioisosterism In Drug Design", ANNUAL REPORTS IN MEDICINAL CHEMISTRY, vol. 21, 1986, pages 283
Type:Non-patent literature
Publication information:  YUN: "Application Of Bioisosterism To New Drug Design", HWAHAK SEKYE, vol. 33, 1993, pages 576 - 579
Type:Non-patent literature
Publication information:  ZHAO, HUAXUE TONGBAO, BIOISOSTERIC REPLACEMENT AND DEVELOPMENT OF LEAD COMPOUNDS IN DRUG DESIGN, 1995, pages 34 - 38
Type:Non-patent literature
Publication information:  GRAHAM; THEOCHEM, THEORETICAL STUDIES APPLIED TO DRUG DESIGN:AB INITIO ELECTRONIC DISTRIBUTIONS IN BIOISOSTERES, vol. 343, 1995, pages 105 - 109
Type:Non-patent literature
Publication information:  T.W. GREEN; P.G.M.WUTS: "Protective Groups in Organic Chemistry", 1991, JOHN WILEY AND SONS
Type:Non-patent literature
Publication information:  T.W. GREENE; P.G.M. WUTS: "Protective Groups in Organic Synthesis, 2nd edition,", 1991, JOHN WILEY & SONS
Type:Non-patent literature
Publication information:  "Nomenclature of a-Amino Acids", BIOCHEMISTRY, vol. 14, no. 2, 1975
Type:Non-patent literature
Publication information:  T.W. GREEN; P.G.M. WUTS: "Protective Groups in Organic Chemistry", 1991, JOHN WILEY AND SONS
Type:Non-patent literature
Publication information:  "Encyclopedia of Pharmaceutical Technology", vol. 10, pages: 33
Type:Non-patent literature
Publication information:  GUILLENA, G. ET AL., J. ORG. CHEM., vol. 65, 2000, pages 7310 - 7322
Type:Non-patent literature
Publication information:  "Design of Prodrugs", 1985, ELSEVIER
Type:Non-patent literature
Publication information:  "Methods in Enzymology", vol. 42, 1985, ACADEMIC PRESS, pages: 309 - 396
Type:Non-patent literature
Publication information:  KROGSGAARD-LARSEN AND H. BANDAGED,: "A Textbook of Drug Design and Developement"
Type:Non-patent literature
Publication information:  DESIGN AND APPLICATIONS OF PRODRUGS, 1991, pages 113 - 191
Type:Non-patent literature
Publication information:  H. BUNDGARD, ADVANCED DRUG DELIVERY REVIEWS, vol. 8, 1992, pages 1 - 38
Type:Non-patent literature
Publication information:  J. PHARM. SCI., vol. 77, 1988, pages 285
Type:Non-patent literature
Publication information:  N. NAKEYA ET AL., CHEM. PHARM. BULL., vol. 32, 1984, pages 692
Type:Non-patent literature
Publication information:  T. HIGUCHI; V. STELLA: "A.C.S. Symposium Series, and Bioreversible Carriers in Drug Design", vol. 14, 1987, AMERICAN PHARMACEUTICAL ASSOCIATION AND PERGAMON PRESS
Type:Non-patent literature
Publication information:  S.M. BERGE ET AL.: "Pharmaceutical Salts", J. PHARM. SCI., vol. 66, 1977, pages 1 - 19