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EP2292233
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EP About this file: EP2292233
| EP2292233 - Pharmaceutical uses of N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine [Right-click to bookmark this link] | Status | The application has been refused Status updated on 11.11.2016 Database last updated on 03.09.2024 | Most recent event Tooltip | 11.11.2016 | Refusal of application | published on 14.12.2016 [2016/50] | Applicant(s) | For all designated states OSI Pharmaceuticals, LLC 1 Astellas Way Northbrook, IL 60062 / US | [2016/42] |
| Former [2011/47] | For all designated states OSI Pharmaceuticals, LLC 1 Bioscience Park Drive Farmingdale, NY 11735 / US | ||
| Former [2011/10] | For all designated states OSI Pharmaceuticals, Inc. 420 Saw Mill River Road Ardsley, New York 10502 / US | Inventor(s) | 01 /
Connell, Richard, D. 23 Jeremy Drive East Lyme, CT 06333 / US | 02 /
Moyer, James, D 5 Jefferson Drive East Lyme, CT 06333 / US | 03 /
Morin, Michael, J 8 Goundry Drive Waterford, CT 06385 / US | 04 /
Kajiji, Shama, M 190 Mistuxet Avenue Mystic, CT 06355 / US | 05 /
Foster, Barbara, A 31 Rossie Street Mystic, CT 06355 / US | 06 /
Ferrante, Karen, J. 10 Adirondack Drive East Greenwich, RI 02818 / US | 07 /
Norris, Timothy 27 Friar Tuck Drive Gales Ferry, CT 06335 / US | 08 /
Raggon, Jeffrey, W 754 Pendleton Drive North Stonington, CT 06339 / US | 09 /
Silberman, Sandra, L 10 Heather Lane Randolph, NJ 07869 / US | [2011/10] | Representative(s) | Crump, Julian Richard John, et al Beresford Crump LLP 16 High Holborn London WC1V 6BX / GB | [N/P] |
| Former [2013/15] | Mintz Levin Cohn Ferris Glovsky and Popeo LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | ||
| Former [2011/10] | Haile, Alison Victoria, et al Mintz Levin, Cohn, Ferris, Glovsky and Popeo IP, LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | Application number, filing date | 10185615.1 | 09.11.2000 | [2011/10] | Priority number, date | US19990164907P | 11.11.1999 Original published format: US 164907 P | US20000193191P | 30.03.2000 Original published format: US 193191 P | US20000206420P | 23.05.2000 Original published format: US 206420 P | [2011/10] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2292233 | Date: | 09.03.2011 | Language: | EN | [2011/10] | Type: | A3 Search report | No.: | EP2292233 | Date: | 27.07.2011 | [2011/30] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 27.06.2011 | Classification | IPC: | A61K31/505, A61P35/00 | [2011/30] | CPC: |
A61K45/06 (EP,US);
C07D239/94 (EP,KR,US);
A61K31/517 (EP,KR,US);
A61P35/00 (EP);
A61P35/04 (EP);
A61P37/02 (EP);
A61P43/00 (EP);
A61P9/10 (EP);
C07D239/86 (KR);
C07D239/88 (KR)
(-)
| C-Set: |
A61K31/517, A61K2300/00 (EP,US)
|
| Former IPC [2011/10] | A61K31/505 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2011/10] | Extension states | AL | 26.01.2012 | LT | 26.01.2012 | LV | 26.01.2012 | MK | 26.01.2012 | RO | 26.01.2012 | SI | 26.01.2012 | Title | German: | Pharmazeutische Verwendungen von N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-chinazolinamin | [2011/10] | English: | Pharmaceutical uses of N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine | [2011/10] | French: | Utilisations pharmaceutiques de N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine | [2011/10] | Examination procedure | 26.01.2012 | Examination requested [2012/10] | 10.05.2012 | Amendment by applicant (claims and/or description) | 09.01.2013 | Despatch of a communication from the examining division (Time limit: M06) | 06.11.2013 | Reply to a communication from the examining division | 26.01.2015 | Despatch of a communication from the examining division (Time limit: M05) | 03.08.2015 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 13.10.2015 | Reply to a communication from the examining division | 10.11.2015 | Observations by third parties | 23.06.2016 | Cancellation of oral proceeding that was planned for 27.06.2016 | 27.06.2016 | Date of oral proceedings (cancelled) | 13.07.2016 | Despatch of communication that the application is refused, reason: substantive examination [2016/50] | 23.07.2016 | Application refused, date of legal effect [2016/50] | Parent application(s) Tooltip | EP00980346.1 / EP1233948 | EP09150479.5 / EP2168581 | Divisional application(s) | EP16177821.2 / EP3100730 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20000980346) is 25.02.2005 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 13.10.2015 | Request for further processing filed | 13.10.2015 | Full payment received (date of receipt of payment) Request granted | 27.10.2015 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the examination report | 06.11.2013 | Request for further processing filed | 06.11.2013 | Full payment received (date of receipt of payment) Request granted | 18.11.2013 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 10.05.2012 | Request for further processing filed | 10.05.2012 | Full payment received (date of receipt of payment) Request granted | 23.05.2012 | Decision despatched | Fees paid | Renewal fee | 01.10.2010 | Renewal fee patent year 03 | 01.10.2010 | Renewal fee patent year 04 | 01.10.2010 | Renewal fee patent year 05 | 01.10.2010 | Renewal fee patent year 06 | 01.10.2010 | Renewal fee patent year 07 | 01.10.2010 | Renewal fee patent year 08 | 01.10.2010 | Renewal fee patent year 09 | 01.10.2010 | Renewal fee patent year 10 | 01.10.2010 | Renewal fee patent year 11 | 25.01.2012 | Renewal fee patent year 12 | 26.11.2012 | Renewal fee patent year 13 | 27.11.2013 | Renewal fee patent year 14 | 26.11.2014 | Renewal fee patent year 15 | 30.11.2015 | Renewal fee patent year 16 | Penalty fee | Additional fee for renewal fee | 30.11.2011 | 12 M06 Fee paid on 25.01.2012 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]WO9630347 (PFIZER [US], et al) [X] 1-12 * page 18, line 16 - line 17; example 20; claim - * * page 19, paragraph 3 *; | [XDY]US5747498 (SCHNUR RODNEY CAUGHREN [US], et al) [XD] 1-12 * column 1; example 20 * * column 14, line 1 - column 15, line 10; claim - * * column 16, line 45 - line 51 * [Y] 10; | [XDY]WO9955683 (PFIZER PROD INC [US], et al) [XD] 1-12 * page 1 - page 2; claim - * [Y] 10; | [XP]EP1044969 (PFIZER PROD INC [US]) [XP] 1-12 * examples 4,7,9-11,13,16 * * page 2, line 5 - line 17 * * page 2, line 37 * * page 6, line 5 - line 6 *; | [XP] - NORRIS T ET AL, "Discovery of a new stable polymorph of 4-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)quinazolinium methanesulfonate using near-infrared spectroscopy to monitor form change kinetics", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 2, CHEMICAL SOCIETY. LETCHWORTH, GB, (2000), vol. 12, ISSN 1472-779X, pages 2498 - 2502, XP002261707 [XP] 1-12 * the whole document * DOI: http://dx.doi.org/10.1039/b003531i | [X] - POLLACK V A ET AL, "INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR-ASSOCIATED TYROSINE PHOSPHORYLATION IN HUMAN CARCINOMAS WITH CP-358,774: DYNAMICS OF RECEPTOR INHIBITION IN SITU AND ANTITUMOR EFFECTS IN ATHYMIC MICE", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND, US, (19991101), vol. 291, no. 2, ISSN 0022-3565, pages 739 - 748, XP001014737 [X] 1-12 * the whole document * | [X] - POLLACK V A ET AL, "THERAPY OF HUMAN CARCINOMAS IN ATHYMIC MICE BY INHIBITION OF EGF RECEPTOR-MEDIATED SIGNAL TRANSDUCTION WITH CP-358774: DYNAMICS OF RECEPTOR INHIBITION AND ANTI-TUMOR EFFECTS", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, (199703), vol. 38, ISSN 0197-016X, page 633, XP001014764 [X] 1-12 * abstract * | [X] - MOYER, JAMES D. ET AL, "Induction of apoptosis and cell cycle arrest by CP-358774, an inhibitor of epidermal growth factor receptor tyrosine kinase", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 128:43513, URL: STN, XP002261709 [X] 1-12 * abstract * | [A] - SMR COMMITEE, "Protein Kinases: Therapeutic Opportunities", THE NEWSLETTER FOR THE SOCIETY FOR MEDICINES RESEARCH, (199907), vol. 5, no. 2, pages 1 - 8, XP002261708 [A] 1-12 * page 5, column L, paragraph 2; examples 8,9 * | [Y] - KREIL A ET AL, "IN-VITRO-EVALUIERUNG POTENTIELL EFFEKTIVER GEMCITABINE-KOMBINATIONSTH ERAPIEN BEIM EXOKRINEN PANKREASKARZINOM//IN VITRO EVALUATION OF POTENTIALLY EFFECTIVE GEMCITABINE-COMBINATION REGIMENS FOR PANCREATIC ADENOCARCINOMA", ACTA MEDICA AUSTRIACA, HOLLINEK, VIENNA, AU, (19990101), vol. 26, no. 3, ISSN 0303-8173, pages 93 - 100, XP009044936 [Y] 10 * page 94; figures 1-5; table 4 * | Examination | US4853221 | - ANONYMOUS, "Non-small-cell lung carcinoma - Wikipedia, the free encyclopedia", (20140825), URL: http://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma, (20150120), XP055163283 | - ANONYMOUS, "OSI Pharmaceuticas Provides Update on Anti-Cancer Programs with Pfizer", (19991117), PR Newswire | - POLLACK V A ET AL, "INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR-ASSOCIATED TYROSINE PHOSPHORYLATION IN HUMAN CARCINOMAS WITH CP-358,774: DYNAMICS OF RECEPTOR INHIBITION IN SITU AND ANTITUMOR EFFECTS IN ATHYMIC MICE", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, US, (19990101), vol. 291, no. 2, ISSN 0022-3565, pages 739 - 748, XP001014737 | - YAN W ET AL, "Squamous cell carcinoma - Similarities and differences among anatomical sites", EMBASE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (2011), Database accession no. 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