Extract from the Register of European Patents

EP About this file: EP2407553

EP2407553 - Gene Expression Markers for Colorectal Cancer Prognosis [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  12.06.2015
Database last updated on 28.02.2026
Most recent event   Tooltip12.06.2015Application deemed to be withdrawnpublished on 15.07.2015  [2015/29]
Applicant(s)For all designated states
Genomic Health, Inc.
301 Penobscot Drive
Redwood City, CA 94063 / US
For all designated states
NSABP Foundation, Inc.
Four Allegheny Center 5th Floor
Pittsburgh PA 15212 / US
[2012/03]
Inventor(s)01 / Cowens, Wayne
P.O. Box 1042
Tiburon, CA 94920 / US
02 / Baker, Joffre
1400 Avery Street
Montara, CA 94037 / US
03 / Hackett, James
2355 Richland Avenue
San Jose, CA 95125 / US
04 / Watson, Drew
1950 Noel Drive
Los Altos, CA 94024 / US
05 / Paik, Soonmyung
210 Timber Ridge Road
Pittsburgh, PA 15238 / US
06 / Clark, Kim
584 Monterey Terrace
Sunnyvale, CA 94089 / US
 [2012/03]
Representative(s)Ellis, Katherine Elizabeth Sleigh
Williams Powell
Staple Court
11 Staple Inn Buildings
London, WC1V 7QH / GB
[N/P]
Former [2012/03]Ellis, Katherine Elizabeth Sleigh
Williams Powell Staple Court 11 Staple Inn Buildings
London, WC1V 7QH / GB
Application number, filing date10194715.811.01.2007
[2012/03]
Priority number, dateUS20060758392P11.01.2006         Original published format: US 758392 P
US20060800277P12.05.2006         Original published format: US 800277 P
US20060810077P31.05.2006         Original published format: US 810077 P
[2012/03]
Previously filed application, dateWO2007US0099511.01.2007
[2012/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2407553
Date:18.01.2012
Language:EN
[2012/03]
Search report(s)(Supplementary) European search report - dispatched on:EP16.12.2011
ClassificationIPC:C12Q1/68, G01N33/574
[2012/03]
CPC:
C12Q1/6886 (EP,KR,US); G01N33/5753 (EP,US); G01N33/57535 (EP,KR,US);
G01N33/57557 (KR); C12Q2600/106 (EP,KR,US); C12Q2600/118 (EP,KR,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2012/03]
TitleGerman:Genexpressionsmarker zur Kolorektalkrebsprognose[2012/03]
English:Gene Expression Markers for Colorectal Cancer Prognosis[2012/03]
French:Marqueurs de l'expression génique pour le pronostic du cancer colorectal[2012/03]
Examination procedure13.12.2010Examination requested  [2012/03]
06.06.2012Amendment by applicant (claims and/or description)
04.07.2013Despatch of a communication from the examining division (Time limit: M06)
18.12.2013Reply to a communication from the examining division
25.07.2014Despatch of a communication from the examining division (Time limit: M06)
05.02.2015Application deemed to be withdrawn, date of legal effect  [2015/29]
27.02.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/29]
Parent application(s)   TooltipEP07717900.0  / EP1974058
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20070717900) is  17.12.2008
Fees paidRenewal fee
13.12.2010Renewal fee patent year 03
13.12.2010Renewal fee patent year 04
14.01.2011Renewal fee patent year 05
11.01.2012Renewal fee patent year 06
10.01.2013Renewal fee patent year 07
21.01.2014Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.01.201509   M06   Not yet paid
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Documents cited:Search[I]   ALAIN BARRIER ET AL: "Gene Expression Profiling of Nonneoplastic Mucosa May Predict Clinical Outcome of Colon Cancer Patients", DISEASES OF THE COLON & RECTUM, SPRINGER-VERLAG, NE, vol. 48, no. 12, 1 December 2005 (2005-12-01), pages 2238 - 2248, XP019368711, ISSN: 1530-0358
 [I]   ARANGO ET AL: "Gene-Expression Profiling Predicts Recurrence in Dukes' C Colorectal Cancer", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, US, vol. 129, no. 3, September 2005 (2005-09-01), pages 874 - 884, XP005314702, ISSN: 0016-5085

DOI:   http://dx.doi.org/10.1053/j.gastro.2005.06.066
 [I]   ROSATI GERARDO ET AL: "Thymidylate synthase expression, p53, bcl-2, Ki-67 and p27 in colorectal cancer: Relationships with tumor recurrence and survival", TUMOR BIOLOGY, KARGER, BASEL, CH, vol. 25, no. 5-6, 2004, pages 258 - 263, XP009087940, ISSN: 1010-4283

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 [I]   SARELA A I ET AL: "EXPRESSION OF THE ANTIAPOPTOSIS GENE, SURVIVIN, PREDICTS DEATH FROM RECURRENT COLORECTAL CARCINOMA", GUT, BRITISH MEDICAL ASSOCIATION, LONDON,, GB, vol. 46, no. 5, May 2000 (2000-05-01), pages 645 - 650, XP001098316, ISSN: 0017-5749

DOI:   http://dx.doi.org/10.1136/gut.46.5.645
 [I]   GLASGOW S C ET AL: "Predictive and prognostic genetic markers in colorectal cancer", SEMINARS IN COLON AND RECTAL SURGERY,, vol. 15, no. 3, 1 January 2005 (2005-01-01), pages 163 - 170, XP009154113, ISSN: 1043-1489

DOI:   http://dx.doi.org/10.1053/j.scrs.2005.02.002
 [I]   KAKISAKO K ET AL: "PROGNOSTIC SIGNIFICANCE OF C-MYC MRNA EXPRESSION ASSESSED BY SEMI-QUANTITATIVE RT-PCR IN PATIENTS WITH COLORECTAL CANCER", ONCOLOGY REPORTS, SPANDIDOS PUBLICATIONS, GR, vol. 5, no. 2, 1 March 1998 (1998-03-01), pages 441 - 445, XP008037557, ISSN: 1021-335X
 [I]   JYOTSNA M. BHATAVDEKAR ET AL: "Coexpression of Bcl-2, c-Myc, and p53 oncoproteins as prognostic discriminants in patients with colorectal carcinoma", DISEASES OF THE COLON & RECTUM, vol. 40, no. 7, 1 July 1997 (1997-07-01), pages 785 - 790, XP055013662, ISSN: 0012-3706, DOI: 10.1007/BF02055433

DOI:   http://dx.doi.org/10.1007/BF02055433
 [I]   JYOTSNA M. BHATAVDEKAR ET AL: "Molecular markers are predictors of recurrence and survival in patients with Dukes B and Dukes C colorectal adenocarcinoma", DISEASES OF THE COLON & RECTUM, vol. 44, no. 4, 1 April 2001 (2001-04-01), pages 523 - 533, XP055013663, ISSN: 0012-3706, DOI: 10.1007/BF02234324

DOI:   http://dx.doi.org/10.1007/BF02234324
 [T]   O'CONNELL MICHAEL J ET AL: "Relationship between tumor gene expression and recurrence in four independent studies of patients with stage II/III colon cancer treated with surgery alone or surgery plus adjuvant fluorouracil plus leucovorin.", JOURNAL OF CLINICAL ONCOLOGY : OFFICIAL JOURNAL OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY 1 SEP 2010 LNKD- PUBMED:20679606, vol. 28, no. 25, 1 September 2010 (2010-09-01), pages 3937 - 3944, XP009151492, ISSN: 1527-7755
 [T]   CLARK-LANGONE KIM M ET AL: "Translating tumor biology into personalized treatment planning: analytical performance characteristics of the Oncotype DX TM Colon Cancer Assay", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 10, no. 1, 23 December 2010 (2010-12-23), pages 691, XP021087208, ISSN: 1471-2407, DOI: 10.1186/1471-2407-10-691

DOI:   http://dx.doi.org/10.1186/1471-2407-10-691
Examination  EMMANOUIL PAPPOU ET AL: "The Role of Oncogenes in Gastrointestinal Cancer", GASTROINTEST CANCER RES, 1 January 2010 (2010-01-01), pages s2 - s15, XP055068397, Retrieved from the Internet [retrieved on 20130626]
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