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Extract from the Register of European Patents

EP About this file: EP2471949

EP2471949 - Method for the identification by molecular techniques of genetic variants that encode no D antigen (D-) and altered C antigen (C+W) [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  31.10.2014
Database last updated on 12.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
[2013/50]
Former [2012/27]For all designated states
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio Vizcaya / ES
Inventor(s)01 / Ochoa, Jorge
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
02 / Lopez, Monica
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
03 / Tejedor, Diego
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
04 / Martinez, Antonio
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
05 / Simon, Laureano
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya
Edificio 504
48160 Derio, Vizcaya / ES
 [2013/50]
Former [2013/34]01 / Ochoa, Jorge
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
02 / Lopez, Monica
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
03 / Tejedor, Diego
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
04 / Martinez, Antonio
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
05 / Simon, Laureano
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
Former [2012/27]01 / Ochoa, Jorge
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
02 / Lopez, Monica
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
03 / Tejedor, Diego
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
04 / Martinez, Antonio
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
05 / Simon, Laureano
Progenika Biopharma, S.A.
Parque Tecnológico de Vizcaya, 801 A
48160 Derio, Vizcaya / ES
Representative(s)Casley, Christopher Stuart, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2013/52]Casley, Christopher Stuart, et al
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Former [2012/27]Casley, Christopher Stuart, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date10197481.431.12.2010
[2012/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2471949
Date:04.07.2012
Language:EN
[2012/27]
Type: B1 Patent specification 
No.:EP2471949
Date:25.12.2013
Language:EN
[2013/52]
Search report(s)(Supplementary) European search report - dispatched on:EP29.04.2011
ClassificationIPC:C12Q1/68
[2012/27]
CPC:
A61K35/14 (US); C12Q1/6881 (EP,US); C12Q2600/156 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/27]
TitleGerman:Verfahren zur Identifizierung durch Molekulartechniken von genetischen Varianten, die kein D-Antigen (D-) und das veränderte C-Antigen (C+W) codieren[2013/32]
English:Method for the identification by molecular techniques of genetic variants that encode no D antigen (D-) and altered C antigen (C+W)[2012/27]
French:Procédé pour l'identification par des techniques moléculaires de variantes génétiques ne codant pas d'antigène D (D-) et qui codent l'antigène C modifié (C+W)[2013/32]
Former [2012/27]Verfahren zur Identifizierung durch Molekulartechniken von genetischen Varianten, die kein D-Antighen (D-) und das veränderte C-Antigen (C+W) codieren
Former [2012/27]Procédé pour l'identification par des techniques moléculaires de variantes génétiques qui ne codent pas pour l'antigène D (D-) et l'antigène C modifié (C+W)
Examination procedure22.03.2012Examination requested  [2012/27]
14.05.2012Amendment by applicant (claims and/or description)
28.08.2012Despatch of a communication from the examining division (Time limit: M06)
06.03.2013Reply to a communication from the examining division
18.04.2013Despatch of a communication from the examining division (Time limit: M04)
19.06.2013Reply to a communication from the examining division
25.07.2013Communication of intention to grant the patent
06.11.2013Fee for grant paid
06.11.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  28.08.2012
Opposition(s)26.09.2014No opposition filed within time limit [2014/49]
Fees paidRenewal fee
20.12.2012Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.12.2010
AL25.12.2013
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
MT25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
TR25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
GR26.03.2014
IS25.04.2014
PT28.04.2014
[2018/46]
Former [2016/32]HU31.12.2010
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
MT25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
TR25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
GR26.03.2014
IS25.04.2014
PT28.04.2014
Former [2016/28]HU31.12.2010
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
MT25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
GR26.03.2014
IS25.04.2014
PT28.04.2014
Former [2015/41]HU31.12.2010
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
GR25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
MT25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2015/38]HU31.12.2010
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
GR25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2015/34]HU31.12.2010
AT25.12.2013
BE25.12.2013
BG25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
LU31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2015/33]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
MK25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2015/24]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SI25.12.2013
SK25.12.2013
SM25.12.2013
IE31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2014/50]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
PL25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SK25.12.2013
IE31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2014/48]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
DK25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SK25.12.2013
IE31.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2014/44]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
MC25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SK25.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2014/37]AT25.12.2013
BE25.12.2013
CY25.12.2013
CZ25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
RO25.12.2013
RS25.12.2013
SE25.12.2013
SK25.12.2013
NO25.03.2014
IS25.04.2014
PT28.04.2014
Former [2014/36]BE25.12.2013
EE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
RS25.12.2013
SE25.12.2013
NO25.03.2014
IS25.04.2014
Former [2014/34]BE25.12.2013
FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
RS25.12.2013
SE25.12.2013
NO25.03.2014
Former [2014/25]FI25.12.2013
HR25.12.2013
LT25.12.2013
LV25.12.2013
RS25.12.2013
SE25.12.2013
NO25.03.2014
Former [2014/24]FI25.12.2013
HR25.12.2013
LT25.12.2013
RS25.12.2013
SE25.12.2013
NO25.03.2014
Former [2014/23]FI25.12.2013
HR25.12.2013
LT25.12.2013
SE25.12.2013
NO25.03.2014
Former [2014/22]FI25.12.2013
LT25.12.2013
SE25.12.2013
NO25.03.2014
Former [2014/20]LT25.12.2013
NO25.03.2014
Documents cited:Search[X]WO2006075254  (PROGENIKA BIOPHARMA SA [ES], et al) [X] 1-15 * page 37, line 7 - page 38, line 16; examples 1,2; sequences 335,403,495-498,627-630 *;
 [Y]WO2006032897  (UNIV BRISTOL [GB], et al) [Y] 1-15 * claim 1 *;
 [Y]DE10049363  (ADNAGEN GMBH [DE]) [Y] 1-15 * paragraphs [0001] , [0009] , [0010] *;
 [E]WO2011003921  (PROGENIKA BIOPHARMA SA [ES], et al) [E] 1-6 * pages 24-26 * * page 6, line 1 - page 7, line 9 *
 [I]  - AVENT N D ET AL, "The bloodgen project of the European Union, 2003-2009", TRANSFUSION MEDICINE AND HEMOTHERAPY 2009 S. KARGER AG CHE LNKD- DOI:10.1159/000218192, (200906), vol. 36, no. 3, ISSN 1660-3796, pages 162 - 167, XP002633276 [I] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1159/000218192
 [XDI]  - WESTHOFF CONNIE M ET AL, "DIIIa and DIII Type 5 are encoded by the same allele and are associated with altered RHCE*ce alleles: clinical implications", TRANSFUSION (MALDEN), (201006), vol. 50, no. 6, ISSN 0041-1132, pages 1303 - 1311, XP002633277 [XD] 1-6 * page 1304, column 2, paragraph 5 - page 1305, column 1, paragraph 1; tables 1-3 * [I] 7-15

DOI:   http://dx.doi.org/10.1111/j.1537-2995.2009.02573.x
 [XDI]  - PHAM BACH-NGA ET AL, "Heterogeneous molecular background of the weak C, VS+, hr(B)-, Hr(B)- phenotype in black persons", TRANSFUSION (MALDEN), (200903), vol. 49, no. 3, ISSN 0041-1132, pages 495 - 504, XP002633278 [XD] 1-6 * abstract * [I] 7-15

DOI:   http://dx.doi.org/10.1111/j.1537-2995.2008.02005.x
 [Y]  - FAAS B H W ET AL, "Rh E/e genotyping by allele-specific primer amplification", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (19950101), vol. 85, no. 3, ISSN 0006-4971, pages 829 - 832, XP002614101 [Y] 1-15 * abstract *
 [Y]  - MAASKANT-VAN WIJK P A ET AL, "GENOTYPING OR RHD BY MULTIPLEX POLYMERASE CHAIN REACTIONS ANALYSIS OF SIX RHD-SPECIFIC EXONS", TRANSFUSION, AMERICAN ASSOCIATION OF BLOOD BANKS, BETHESDA, MD, US, (19981101), vol. 11, no. 38, doi:10.1046/J.1537-2995.1998.38111299056309.X, ISSN 0041-1132, pages 1015 - 1021, XP008005129 [Y] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1046/j.1537-2995.1998.38111299056309.x
by applicantWO2009000084
 WO2010000210
 WO2010000380
 WO2010000635
 WO2010000972
 WO2010002366
 WO2010002367
 WO2010003113
 WO2010003649
 WO2010003664
 WO2010003809
    - CONNIE M.; WESTHOFF, SUNITHA VEGE; CHRISTINE HALTER-HIPSKY; TRINA WHORLEY; KIM HUE-ROYE; CHRISTINE LOMAS-FRANCIS; MARION E., "Dllla and Dill Type 5 are encoded by the same allele and are associated with altered RHCE*ce alleles: clinical implications", REID. TRANSFUSION, (2010), vol. 50, pages 1303 - 1311
    - BACH-NGA PHAM; THIERRY PEYRARD; GENEVIEVE JUSZCZAK; ISABELLE DUBEAUX; DOMINIQUE GIEN; ANTOINE BLANCHER; JEAN-PIERRE CARTRON; PHILI, "Heterogeneous molecular background of the weak C, VS+, hrB-, HrB- phenotype in black persons", TRANSFUSION, (2009), vol. 49, pages 495 - 504
    - MARTINE G.H.M.; TAX, C.; ELLEN VAN DER SCHOOT; RENE' VAN DOORN; LOTTE DOUGLAS-BERGER; DICK J.; VAN RHENEN; PETRA A.; MAASKANT-VAN, "RHC and RHc genotyping in different ethnic groups", TRANSFUSION, (2002), vol. 42, pages 6234 - 644
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.