EP2385839 - THERAPEUTIC COMPOSITIONS FOR TREATMENT OF CORNEAL DISORDERS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 02.10.2015 Database last updated on 19.07.2024 | Most recent event Tooltip | 22.06.2018 | Lapse of the patent in a contracting state New state(s): MK | published on 25.07.2018 [2018/30] | Applicant(s) | For all designated states THE SCHEPENS EYE RESEARCH INSTITUTE, INC. 20 Staniford Street Boston, MA 02114 / US | [2011/46] | Inventor(s) | 01 /
DANA, Reza 165 Pleasant Street Cambridge MA 02139 / US | 02 /
DASTJERDI, Mohammed 9408 Alhambra Street Prairie Village KS 66207 / US | 03 /
CHAUHAN, Sunil 85 Mt. Vernon Street Apt. 4 Somerville, MA 02145 / US | [2011/46] | Representative(s) | Lahrtz, Fritz, et al Patentanwälte Isenbruck Bösl Hörschler PartG mbB Prinzregentenstraße 68 81675 München / DE | [N/P] |
Former [2013/15] | Mintz Levin Cohn Ferris Glovsky and Popeo LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | ||
Former [2011/46] | Clarke, Victoria, et al Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP Alder Castle 10 Noble Street London EC2V 7JX / GB | Application number, filing date | 10700459.0 | 11.01.2010 | WO2010US20646 | Priority number, date | US20090143561P | 09.01.2009 Original published format: US 143561 P | [2011/46] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2010081091 | Date: | 15.07.2010 | Language: | EN | [2010/28] | Type: | A2 Application without search report | No.: | EP2385839 | Date: | 16.11.2011 | Language: | EN | The application published by WIPO in one of the EPO official languages on 15.07.2010 takes the place of the publication of the European patent application. | [2011/46] | Type: | B1 Patent specification | No.: | EP2385839 | Date: | 26.11.2014 | Language: | EN | [2014/48] | Search report(s) | International search report - published on: | EP | 18.11.2010 | Classification | IPC: | A61K38/17, C12N15/113, A61P27/02, A61K38/20, A61K9/00 | [2014/28] | CPC: |
A61K38/1709 (EP,US);
A61K38/1793 (EP,US);
A61K38/2006 (EP,US);
A61K9/0048 (EP,US);
A61P27/02 (EP);
A61P37/00 (EP);
| C-Set: |
A61K38/1709, A61K2300/00 (EP,US)
|
Former IPC [2011/46] | A61K38/17, C12N15/113, A61P27/02 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2014/48] | Extension states | AL | Not yet paid | BA | Not yet paid | RS | Not yet paid | Title | German: | THERAPEUTISCHE ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON HORNHAUTERKRANKUNGEN | [2011/46] | English: | THERAPEUTIC COMPOSITIONS FOR TREATMENT OF CORNEAL DISORDERS | [2011/46] | French: | COMPOSITIONS THÉRAPEUTIQUES POUR LE TRAITEMENT DE TROUBLES DE LA CORNÉE | [2011/46] | Entry into regional phase | 08.08.2011 | National basic fee paid | 08.08.2011 | Designation fee(s) paid | 08.08.2011 | Examination fee paid | Examination procedure | 08.08.2011 | Examination requested [2011/46] | 09.03.2012 | Amendment by applicant (claims and/or description) | 02.01.2013 | Despatch of a communication from the examining division (Time limit: M06) | 19.08.2013 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 18.10.2013 | Reply to a communication from the examining division | 28.05.2014 | Cancellation of oral proceeding that was planned for 03.06.2014 | 03.06.2014 | Date of oral proceedings (cancelled) | 08.07.2014 | Communication of intention to grant the patent | 16.10.2014 | Fee for grant paid | 16.10.2014 | Fee for publishing/printing paid | 16.10.2014 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 02.01.2013 | Opposition(s) | 27.08.2015 | No opposition filed within time limit [2015/45] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 18.10.2013 | Request for further processing filed | 18.10.2013 | Full payment received (date of receipt of payment) Request granted | 31.10.2013 | Decision despatched | Fees paid | Renewal fee | 25.01.2012 | Renewal fee patent year 03 | 25.01.2013 | Renewal fee patent year 04 | 27.01.2014 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 11.01.2010 | AT | 26.11.2014 | BG | 26.11.2014 | CY | 26.11.2014 | CZ | 26.11.2014 | DK | 26.11.2014 | EE | 26.11.2014 | ES | 26.11.2014 | FI | 26.11.2014 | HR | 26.11.2014 | IT | 26.11.2014 | LT | 26.11.2014 | LV | 26.11.2014 | MK | 26.11.2014 | NL | 26.11.2014 | PL | 26.11.2014 | RO | 26.11.2014 | SE | 26.11.2014 | SI | 26.11.2014 | SK | 26.11.2014 | SM | 26.11.2014 | TR | 26.11.2014 | NO | 26.02.2015 | GR | 27.02.2015 | IS | 26.03.2015 | PT | 26.03.2015 | [2018/30] |
Former [2017/38] | HU | 11.01.2010 | |
AT | 26.11.2014 | ||
BG | 26.11.2014 | ||
CY | 26.11.2014 | ||
CZ | 26.11.2014 | ||
DK | 26.11.2014 | ||
EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
HR | 26.11.2014 | ||
IT | 26.11.2014 | ||
LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
PL | 26.11.2014 | ||
RO | 26.11.2014 | ||
SE | 26.11.2014 | ||
SI | 26.11.2014 | ||
SK | 26.11.2014 | ||
SM | 26.11.2014 | ||
TR | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2016/12] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
CZ | 26.11.2014 | ||
DK | 26.11.2014 | ||
EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
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SI | 26.11.2014 | ||
SK | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2016/03] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
CZ | 26.11.2014 | ||
DK | 26.11.2014 | ||
EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
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LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
PL | 26.11.2014 | ||
RO | 26.11.2014 | ||
SE | 26.11.2014 | ||
SK | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/37] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
CZ | 26.11.2014 | ||
DK | 26.11.2014 | ||
EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
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LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
PL | 26.11.2014 | ||
RO | 26.11.2014 | ||
SE | 26.11.2014 | ||
SK | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/36] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
CZ | 26.11.2014 | ||
DK | 26.11.2014 | ||
EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
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SE | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/35] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
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EE | 26.11.2014 | ||
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
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LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
SE | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/26] | AT | 26.11.2014 | |
CY | 26.11.2014 | ||
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
HR | 26.11.2014 | ||
LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
SE | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/25] | AT | 26.11.2014 | |
ES | 26.11.2014 | ||
FI | 26.11.2014 | ||
HR | 26.11.2014 | ||
LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
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SE | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/24] | ES | 26.11.2014 | |
FI | 26.11.2014 | ||
HR | 26.11.2014 | ||
LT | 26.11.2014 | ||
LV | 26.11.2014 | ||
NL | 26.11.2014 | ||
SE | 26.11.2014 | ||
NO | 26.02.2015 | ||
GR | 27.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/23] | ES | 26.11.2014 | |
FI | 26.11.2014 | ||
LT | 26.11.2014 | ||
NL | 26.11.2014 | ||
NO | 26.02.2015 | ||
IS | 26.03.2015 | ||
PT | 26.03.2015 | ||
Former [2015/22] | LT | 26.11.2014 | |
NO | 26.02.2015 | ||
PT | 26.03.2015 | ||
Former [2015/21] | LT | 26.11.2014 | |
NO | 26.02.2015 | ||
Former [2015/20] | LT | 26.11.2014 | Cited in | International search | [XI]WO9822130 (SCHEPENS EYE RES INST [US], et al) [X] 1-17,20,21 * abstract * * page 19, line 32 - page 20, line 5 * [I] 18,19,22,33; | [XP]WO2009089036 (SCHEPENS EYE RES INST [US], et al) [XP] 1-22 * claims 33-41 * | [XI] - BISWAS PARTHA SARATHI ET AL, "Counteracting corneal immunoinflammatory lesion with interleukin-1 receptor antagonist protein", JOURNAL OF LEUKOCYTE BIOLOGY, (200410), vol. 76, no. 4, ISSN 0741-5400, pages 868 - 875, XP002582634 [X] 1-17,20,21 * abstract * [I] 18,19,22,33 | [XI] - BARRETT R ET AL, "Combined antibiotic and IL-1 receptor antagonist treatment decreases stromal inflammation after P. aeruginosa induced keratitis", IOVS, & ANNUAL MEETING OF THE ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY; FORT LAUDERDALE, FLORIDA, USA; APRIL 29-MAY 04, 2001, (20010315), vol. 42, no. 4, page S252, XP009133601 [X] 1-17,20,21 * abstract * [I] 18,19,22,33 | [XI] - YAMADA JUN ET AL, "Local suppression of IL-1 by receptor antagonist in the rat model of corneal alkali injury.", EXPERIMENTAL EYE RESEARCH FEB 2003 LNKD- PUBMED:12565803, (200302), vol. 76, no. 2, ISSN 0014-4835, pages 161 - 167, XP002582629 [X] 1-17,20,21 * abstract * [I] 18,19,22,33 DOI: http://dx.doi.org/10.1016/S0014-4835(02)00293-2 | [XI] - JIE YING ET AL, "Interleukin-1 receptor antagonist eye drops promoting high-risk corneal allografts survival in rats", CHINESE MEDICAL JOURNAL (ENGLISH EDITION), (200405), vol. 117, no. 5, ISSN 0366-6999, pages 711 - 716, XP009133597 [X] 1-17,20,21 * abstract * [I] 18,19,22,33 | by applicant | US2005033694 | US2001041792 | US6974682 | US2006094663 | US2005171337 | US2005105830 | US2001042304 | US6927044 | US2003026806 | US2004022718 | US2005023872 | US6623736 | US2003083301 | US2009136453 | US2008242634 | WO2009089036 | - YAMASAKI ET AL., STROKE, (1995), vol. 26, pages 676 - 681 | - BERNOIST ET AL., NATURE, (1981), vol. 290, page 304 | - YAMAMOTO ET AL., CELL, (1988), vol. 22, pages 787 - 797 | - WAGNER ET AL., PROC. NATL. ACAD. SCI. USA, (1981), vol. 78, page 1441 | - BRINSTER ET AL., NATURE, (1988), vol. 296, page 39 | - PONS ET AL., EUR. RESPIR. J., (2002), vol. 20, pages 458 - 463 | - AKEDA ET AL., SPINE, (2007), vol. 32, pages 635 - 642 | - DEKOSKY ET AL., ANN. NEUROL., (1996), vol. 39, pages 123 - 127 | - TEMPORIN ET AL., NEUROSCI LETT., (2008), vol. 440, no. 2, pages 130 - 3 | - RYOKE ET AL., BIOCHEM BIOPHYS RES COMMUN., (2000), vol. 267, no. 3, pages 715 - 8 | - GUCNARD ET AL., J NCUROSCI RCS., (1991), vol. 29, no. 3, pages 396 - 400 | - MüLLER ET AL., EXP EYE RES, (2003), vol. 76, pages 521 - 42 | - MüLLCR ET AL., INVEST OPHTHALMOL VIS SCI, (1996), vol. 37, pages 476 - 88 | - DARTT, DA, OCUL SURF, (2004), vol. 2, pages 76 - 91 | - BATTAT ET AL., OPHTHALMOLOGY, (2001), vol. 108, pages 1230 - 5 | - XU, CORNEA, (1996), vol. 15, pages 235 - 9 | - DINARELLO, C.A., BLOOD, (1996), vol. 15, pages 2095 - 2147 | - JIANG, Y. ET AL., ARTHRITIS RHEUM., (2000), vol. 43, pages 1001 - 1009 | - OKUSAWA, S. ET AL., J CLIN INVEST., (1988), vol. 81, pages 1162 - 1172 | - MCDEVITT, M.J. ET AL., J. PERIODONTOL., (2000), vol. 71, pages 156 - 163 | - AREND, W.P., ADV IMMUNOL., (1993), vol. 54, pages 167 - 223 | - FISHER, C.J., JAMA, (1994), vol. 271, pages 1836 - 1843 | - BRESNIHAN, B. ET AL., RHEUM DIS CLIN NORTH AM., (1998), vol. 24, no. 3, pages 615 - 628 | - DAYER, J.M., CURR OPIN RHCUMATOL., (2001), vol. 13, pages 170 - 176 | - EDWARDS, C.K., J CLIN RHCUMATOL., (2001), vol. 7, pages S17 - S24 | - REIFF, A., CURR RHEUMATOL REP., (2005), vol. 7, pages 434 - 40 | - ANTIN, J.H. ET AL., BLOOD, (1994), vol. 84, pages 1342 - 8 | - TEOH, S.C. ET AL., BR J OPTHALMOL., (2007), vol. 91, pages 263 - 4 | - CARON, J.P ET AL., ARTHRITIS RHEUM., (1996), vol. 39, pages 1535 - 44 | - HYNNINEN, M. ET AL., J CRIT CARE., (1999), vol. 14, pages 63 - 8 | - LARSEN, C.M. ET AL., N ENGL J. MED., (2007), vol. 356, pages 1517 - 26 | - YAMADA, J. ET AL., INVEST OPTHALMOL VIS SCI., (2000), vol. 41, pages 4203 - 8 | - KEANE-MYERS, A.M. ET AL., INVEST OPTHALMOL VIS SCI., (1999), vol. 40, pages 3041 - 6 | - YAMADA, J. ET AL., EXP EYE RES., (2003), vol. 76, pages 161 - 7 | - O'NCILL, L. A. J.; GREENE, C., JOURNAL OF LEUKOCYTE BIOLOGY., (1998), vol. 63, pages 650 - 657 | - FOULKS; BRON, OCUL SURF, (2003), pages 107 - 26 | WO2008US09776 |