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Extract from the Register of European Patents

EP About this file: EP2408735

EP2408735 - PROCESS FOR THE PREPARATION OF TRIIODINATED CARBOXYLIC AROMATIC DERIVATIVES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.04.2014
Database last updated on 15.07.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
Bracco Imaging S.p.A.
Via Egidio Folli 50
20134 Milano / IT
[N/P]
Former [2012/04]For all designated states
Bracco Imaging S.p.A
Via Egidio Folli 50
20134 Milano / IT
Inventor(s)01 / ANELLI, Pier Lucio
Bracco Imaging SpA - CRB
Via Ribes 5
Colleretto Giacosa
I-10010 Ivrea / IT
02 / BROCCHETTA, Marino
Via Oberdan
25
I-27100 Pavia / IT
03 / FRETTA, Roberta
Bracco Imaging SpA - CRB
Via Ribes 5
Colleretto Giacosa
I-10010 Ivrea / IT
04 / LATTUADA, Luciano
Bracco Imaging SpA - CRB
Via Ribes 5
Colleretto Giacosa
I-10010 Ivrea / IT
05 / MORTILLARO, Armando
Bracco Imaging SpA - CRB
Via Ribes 5
Colleretto Giacosa
I-10010 Ivrea / IT
 [2012/04]
Representative(s)Merli, Silvia
Bracco Imaging SpA
IP Department
Via Caduti di Marcinelle 13
20134 Milano / IT
[N/P]
Former [2012/04]Merli, Silvia
Intellectual Property Department Bracco Imaging SpA Via XXV Aprile 4
20097 San Donato Milanese (MI) / IT
Application number, filing date10708209.112.03.2010
WO2010EP53186
Priority number, dateEP2009015569520.03.2009         Original published format: EP 09155695
[2012/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010105983
Date:23.09.2010
Language:EN
[2010/38]
Type: A1 Application with search report 
No.:EP2408735
Date:25.01.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 23.09.2010 takes the place of the publication of the European patent application.
[2012/04]
Type: B1 Patent specification 
No.:EP2408735
Date:05.06.2013
Language:EN
[2013/23]
Search report(s)International search report - published on:EP23.09.2010
ClassificationIPC:C07C231/10, C07C231/02, C07C235/16, C07C237/46
[2012/50]
CPC:
C07C237/46 (EP,KR,US); C07C231/10 (EP,KR,US); C07C231/02 (EP,US);
C07C235/16 (KR); C07C235/68 (KR); Y02P20/55 (EP)
C-Set:
C07C231/02, C07C235/16 (EP,US);
C07C231/02, C07C237/46 (US,EP);
C07C231/10, C07C235/16 (US,EP);
C07C231/10, C07C237/46 (US,EP)
Former IPC [2012/04]C07C231/10, C07C235/16, C07C237/52
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/04]
Extension statesALNot yet paid
BANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON AROMATISCHEN TRIJODID-CARBOXYL- DERIVATEN[2012/50]
English:PROCESS FOR THE PREPARATION OF TRIIODINATED CARBOXYLIC AROMATIC DERIVATIVES[2012/04]
French:Procédé de préparation de dérivés aromatiques carboxyliques tri-iodés[2012/50]
Former [2012/04]VERFAHREN ZUR HERSTELLUNG VON DREIFACH IODIERTEN, AROMATISCHEN CARBONSÄUREDERIVATEN
Former [2012/04]PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS AROMATIQUES CARBOXYLIQUES TRIIODÉS
Entry into regional phase18.10.2011National basic fee paid 
18.10.2011Designation fee(s) paid 
18.10.2011Examination fee paid 
Examination procedure18.10.2011Amendment by applicant (claims and/or description)
18.10.2011Examination requested  [2012/04]
21.12.2012Communication of intention to grant the patent
17.04.2013Fee for grant paid
17.04.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.12.2012
Opposition(s)06.03.2014No opposition filed within time limit [2014/20]
Fees paidRenewal fee
26.03.2012Renewal fee patent year 03
27.03.2013Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.03.2010
BE05.06.2013
CY05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MC05.06.2013
MK05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
TR05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
[2018/30]
Former [2016/33]HU12.03.2010
BE05.06.2013
CY05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MC05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
TR05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2016/32]HU12.03.2010
BE05.06.2013
CY05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MC05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2016/31]BE05.06.2013
CY05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MC05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2016/27]BE05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MC05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2016/22]BE05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
SM05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2016/12]BE05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
MT05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2014/21]BE05.06.2013
CZ05.06.2013
DK05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2014/14]BE05.06.2013
CZ05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
NL05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2014/11]BE05.06.2013
CZ05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
PL05.06.2013
RO05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2014/10]BE05.06.2013
CZ05.06.2013
EE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
SE05.06.2013
SI05.06.2013
SK05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
IS05.10.2013
PT07.10.2013
Former [2014/08]BE05.06.2013
FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
SE05.06.2013
SI05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
PT07.10.2013
Former [2014/02]FI05.06.2013
HR05.06.2013
LT05.06.2013
LV05.06.2013
SE05.06.2013
SI05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
Former [2013/51]FI05.06.2013
HR05.06.2013
LT05.06.2013
SE05.06.2013
SI05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
Former [2013/50]FI05.06.2013
LT05.06.2013
SE05.06.2013
SI05.06.2013
BG05.09.2013
NO05.09.2013
GR06.09.2013
Former [2013/49]FI05.06.2013
LT05.06.2013
SE05.06.2013
SI05.06.2013
NO05.09.2013
GR06.09.2013
Former [2013/47]LT05.06.2013
NO05.09.2013
Cited inInternational search[AD]DE1085648  (LENTIA GMBH, et al) [AD] 1 * column 2, line 37 - column 3, line 58 *;
 [AD]WO9637459  (FRUCTAMINE SPA [IT], et al) [AD] 1-15 * page 3, line 3 - line 19; example 16; claim 12 *;
 [AD]WO0244132  (BRACCO IMAGING SPA [IT], et al) [AD] 1-15 * page 1 *;
 [AD]  - CHIDAMBARAM R ET AL, "Reaction of electron-deficient N-sulfinylanilines with chiral alpha-hydroxy acids: a new process for the synthesis of enantiomerically pure alpha-hydroxy amides", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, (20000805), vol. 41, no. 32, ISSN 0040-4039, pages 6017 - 6020, XP004243504 [AD] 1-15 * page 6019; table 1 *

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)01011-X
 [AD]  - "NEW FACILE SYNTHESIS OF ALPHA HYDROXYAMIDES INTERMOLECULAR AND INTRAMOLECULAR CATALYSIS IN THE REACTION OF ALPHA HYDROXYCARBOXYLIC ACIDS WITH N SULFINYLAMINES", TETRAHEDRON LETTERS, (1986), vol. 27, no. 17, ISSN 0040-4039, pages 1921 - 1924, XP002541119 [AD] 1-15 * Scheme I;; page 1921; table I *

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)84412-3
 [AD]  - HANESSIAN ET AL, "omega-Alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: A study of chain-length and stereochemical dependence", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, (20071012), vol. 17, no. 22, ISSN 0960-894X, pages 6261 - 6265, XP022297139 [AD] 1-15 * Schemes 1-3 *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2007.09.014
 [AD]  - R. CHIDAMBARAM, J. KANT, J. ZHU, J. LAJEUNESSE, P. SIRARD, P. ERMANN, P. SCHIERLING, P. LEE, D. KRONENTHAL, "A Practical Synthesis of the RARç Agonist, BMS-270394", ORGANIC PROCESS RESEARCH & DEVELOPMENT, (20020724), vol. 6, pages 632 - 636, XP002541120 [AD] 1-15 * Scheme 4;; pages 633-635 *

DOI:   http://dx.doi.org/10.1021/op0202134
 [A]  - ULRICH JAGER, MICHAEL SCHWAB UND WOLFGANG SUNDERMEYER, "Fluorsubstituierte l,2-Thiazetan-3-nn-l-oxide durch Reaktion von Bis(trifluormethyl)keten mit N-Sulfinylaminen", CHEM. BER., (1986), vol. 119, pages 1127 - 1132, XP002541121 [A] 1 * pages 1130-1; compound 2D *

DOI:   http://dx.doi.org/10.1002/cber.19861190404
by applicantDE1085648
 GB1472050
 WO9414478
 US5362905
 WO9637459
 WO9637460
 WO9637458
 WO9747590
 WO9824757
 WO9828259
 WO9958494
 WO0244132
    - BIOORG. MED. CHEM. LETT., (2006), vol. 16, pages 4784 - 4787
    - BIOORG. MED. CHEM. LETT., (2007), vol. 17, pages 6261 - 6265
    - TETRAHEDRON LETT., (2000), vol. 41, pages 6017 - 6020
    - TETRAHEDRON LETT., (1986), vol. 27, pages 1921 - 1924
    - PILLAI ET AL., J. ORG. CHEM., (1994), vol. 59, pages 1344 - 50
    - HARRIE J.M. ET AL., ORG. PROC. RES. DEV., (1999), vol. 3, pages 38 - 43
    - BULL., KOREAN CHEM. SOC., (1990), vol. 11, pages 494 - 496
    - CHIDAMBARAM ET AL., ORGANIC PROCESS RESEARCH & DEVELOPMENT, (2002), vol. 6, pages 632 - 636
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.